Radioiodine-remnant ablation in low-risk differentiated thyroid cancer: pros View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2015-09

AUTHORS

Kenneth B. Ain

ABSTRACT

Differentiated thyroid carcinomas are typically treated with total thyroidectomy as initial therapy. Subsequent radioactive iodine (RAI) ablation destroys post-surgical thyroid remnants, can additionally provide adjuvant therapy of residual and metastatic thyroid cancers, and enhances the sensitivity and specificity of further diagnostic studies. There is current controversy regarding whether a large number of patients, broadly considered to have "low-risk" disease, should be provided RAI ablation. This is consequent to over-reliance on short-term studies, under-appreciation of the value of RAI remnant ablation, and inflation of the side effects of RAI therapy. A balanced assessment of all of these issues provides justification to utilize post-surgical radioiodine ablation, even in cases that are considered low risk on the basis of surgical findings. More... »

PAGES

61-66

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s12020-015-0668-9

DOI

http://dx.doi.org/10.1007/s12020-015-0668-9

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1027861444

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/26109472


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1102", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Cardiorespiratory Medicine and Haematology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Iodine Radioisotopes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neoplasm, Residual", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Thyroid Neoplasms", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Lexington VA Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.413837.a", 
          "name": [
            "Thyroid Oncology Program, Markey Cancer Center, University of Kentucky, 800 Rose Street, 40536, Lexington, KY, USA", 
            "Thyroid Cancer Research Laboratory, Veterans Affairs Medical Center, Lexington, KY, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ain", 
        "givenName": "Kenneth B.", 
        "id": "sg:person.01125651276.60", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01125651276.60"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/j.ecl.2008.02.007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001831490"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10654-014-9971-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004882245", 
          "https://doi.org/10.1007/s10654-014-9971-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0360-3016(85)90126-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005115134"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.clon.2010.05.004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005584603"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.0272-4332.2004.00433.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006009888"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.0272-4332.2004.00433.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006009888"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/thy.2014.0162", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007997021"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cll.2004.01.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009966218"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/archsurg.141.5.489", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011670604"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000204465", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012167905"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/jnci/dji140", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013363968"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/jnci/dji140", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013363968"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/ta.0b013e3181848caa", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016432658"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/ta.0b013e3181848caa", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016432658"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.amjmed.2009.08.006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017765770"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/thy.2009.0110", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018764357"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2217/ije.14.24", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019443110"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrendo.2011.142", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021894967", 
          "https://doi.org/10.1038/nrendo.2011.142"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2265.2012.04342.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024695976"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.canlet.2013.09.018", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025557391"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1667/rr13849.1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027176828"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/1-4020-8107-3_20", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030092559", 
          "https://doi.org/10.1007/1-4020-8107-3_20"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10620-009-1009-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032607189", 
          "https://doi.org/10.1007/s10620-009-1009-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10620-009-1009-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032607189", 
          "https://doi.org/10.1007/s10620-009-1009-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.1365-2265.2002.t01-1-01545.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032611536"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-1-4419-0857-5_1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036124131", 
          "https://doi.org/10.1007/978-1-4419-0857-5_1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-1-4419-0857-5_1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036124131", 
          "https://doi.org/10.1007/978-1-4419-0857-5_1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.surg.2012.02.015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036450307"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0002-9343(94)90321-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036476235"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jso.23345", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039761838"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jama.287.5.622", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045570425"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0167-8140(89)90006-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049870733"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0167-8140(89)90006-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049870733"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2265.2008.03222.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050098322"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/annonc/mdu225", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051908923"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3349/ymj.2009.50.6.744", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052278552"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1530/erc-14-0286", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052526496"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa1209288", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053356019"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1677/erc.1.01320", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053545082"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1677/erc.1.01320", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053545082"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/606060", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1058810527"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/105072503321582060", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059204488"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/thy.2008.0392", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059320438"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/thy.2009.1611", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059320748"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/thy.2011.0522", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059321320"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/thy.2012.0043", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059321414"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/thy.2012.0043", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059321414"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/thy.2012.0422", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059321528"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/thy.2012.0422", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059321528"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/thy.2013.0011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059321655"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/thy.2013.0011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059321655"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1207/s15324796abm3101_8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064220551", 
          "https://doi.org/10.1207/s15324796abm3101_8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1207/s15324796abm3101_8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064220551", 
          "https://doi.org/10.1207/s15324796abm3101_8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/jc.2004-0739", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064287859"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/jc.2004-0920", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064287910"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/jc.2005-1322", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064288644"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/jc.2005-2838", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064289036"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/jc.2008-1931", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064290978"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/jc.2012-3630", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064293962"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/jc.2014-1631", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064295105"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/jc.84.7.2449", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064300883"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/jcem.78.3.8126134", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064318598"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/jcem.84.11.6115", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064322264"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/jcem.86.4.7407", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064324318"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2015-09", 
    "datePublishedReg": "2015-09-01", 
    "description": "Differentiated thyroid carcinomas are typically treated with total thyroidectomy as initial therapy. Subsequent radioactive iodine (RAI) ablation destroys post-surgical thyroid remnants, can additionally provide adjuvant therapy of residual and metastatic thyroid cancers, and enhances the sensitivity and specificity of further diagnostic studies. There is current controversy regarding whether a large number of patients, broadly considered to have \"low-risk\" disease, should be provided RAI ablation. This is consequent to over-reliance on short-term studies, under-appreciation of the value of RAI remnant ablation, and inflation of the side effects of RAI therapy. A balanced assessment of all of these issues provides justification to utilize post-surgical radioiodine ablation, even in cases that are considered low risk on the basis of surgical findings. ", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s12020-015-0668-9", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1112251", 
        "issn": [
          "1355-008X", 
          "1559-0100"
        ], 
        "name": "Endocrine", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "50"
      }
    ], 
    "name": "Radioiodine-remnant ablation in low-risk differentiated thyroid cancer: pros", 
    "pagination": "61-66", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "84b91a07e7a2640ab9d245804bee5a492651e4efb2c991e2e3a5c1d49e0918e8"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "26109472"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "9434444"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s12020-015-0668-9"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1027861444"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s12020-015-0668-9", 
      "https://app.dimensions.ai/details/publication/pub.1027861444"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T02:08", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8700_00000522.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007%2Fs12020-015-0668-9"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s12020-015-0668-9'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s12020-015-0668-9'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s12020-015-0668-9'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s12020-015-0668-9'


 

This table displays all metadata directly associated to this object as RDF triples.

251 TRIPLES      21 PREDICATES      86 URIs      25 LITERALS      13 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s12020-015-0668-9 schema:about N2440305e81c64ebf868b0c2ce674f2c2
2 N5240bbecc5bb480b9e4074e1b9561ebd
3 N8187459331cb48b3a87d8f77f40687ab
4 Nf4b163622c194cc7a3f2f8fe65a41cb5
5 anzsrc-for:11
6 anzsrc-for:1102
7 schema:author N9f7ee0bd89454564b7cc4babfb056423
8 schema:citation sg:pub.10.1007/1-4020-8107-3_20
9 sg:pub.10.1007/978-1-4419-0857-5_1
10 sg:pub.10.1007/s10620-009-1009-8
11 sg:pub.10.1007/s10654-014-9971-7
12 sg:pub.10.1038/nrendo.2011.142
13 sg:pub.10.1207/s15324796abm3101_8
14 https://doi.org/10.1001/archsurg.141.5.489
15 https://doi.org/10.1001/jama.287.5.622
16 https://doi.org/10.1002/jso.23345
17 https://doi.org/10.1016/0002-9343(94)90321-2
18 https://doi.org/10.1016/0167-8140(89)90006-6
19 https://doi.org/10.1016/0360-3016(85)90126-9
20 https://doi.org/10.1016/j.amjmed.2009.08.006
21 https://doi.org/10.1016/j.canlet.2013.09.018
22 https://doi.org/10.1016/j.cll.2004.01.001
23 https://doi.org/10.1016/j.clon.2010.05.004
24 https://doi.org/10.1016/j.ecl.2008.02.007
25 https://doi.org/10.1016/j.surg.2012.02.015
26 https://doi.org/10.1046/j.1365-2265.2002.t01-1-01545.x
27 https://doi.org/10.1056/nejmoa1209288
28 https://doi.org/10.1086/606060
29 https://doi.org/10.1089/105072503321582060
30 https://doi.org/10.1089/thy.2008.0392
31 https://doi.org/10.1089/thy.2009.0110
32 https://doi.org/10.1089/thy.2009.1611
33 https://doi.org/10.1089/thy.2011.0522
34 https://doi.org/10.1089/thy.2012.0043
35 https://doi.org/10.1089/thy.2012.0422
36 https://doi.org/10.1089/thy.2013.0011
37 https://doi.org/10.1089/thy.2014.0162
38 https://doi.org/10.1093/annonc/mdu225
39 https://doi.org/10.1093/jnci/dji140
40 https://doi.org/10.1097/ta.0b013e3181848caa
41 https://doi.org/10.1111/j.0272-4332.2004.00433.x
42 https://doi.org/10.1111/j.1365-2265.2008.03222.x
43 https://doi.org/10.1111/j.1365-2265.2012.04342.x
44 https://doi.org/10.1159/000204465
45 https://doi.org/10.1210/jc.2004-0739
46 https://doi.org/10.1210/jc.2004-0920
47 https://doi.org/10.1210/jc.2005-1322
48 https://doi.org/10.1210/jc.2005-2838
49 https://doi.org/10.1210/jc.2008-1931
50 https://doi.org/10.1210/jc.2012-3630
51 https://doi.org/10.1210/jc.2014-1631
52 https://doi.org/10.1210/jc.84.7.2449
53 https://doi.org/10.1210/jcem.78.3.8126134
54 https://doi.org/10.1210/jcem.84.11.6115
55 https://doi.org/10.1210/jcem.86.4.7407
56 https://doi.org/10.1530/erc-14-0286
57 https://doi.org/10.1667/rr13849.1
58 https://doi.org/10.1677/erc.1.01320
59 https://doi.org/10.2217/ije.14.24
60 https://doi.org/10.3349/ymj.2009.50.6.744
61 schema:datePublished 2015-09
62 schema:datePublishedReg 2015-09-01
63 schema:description Differentiated thyroid carcinomas are typically treated with total thyroidectomy as initial therapy. Subsequent radioactive iodine (RAI) ablation destroys post-surgical thyroid remnants, can additionally provide adjuvant therapy of residual and metastatic thyroid cancers, and enhances the sensitivity and specificity of further diagnostic studies. There is current controversy regarding whether a large number of patients, broadly considered to have "low-risk" disease, should be provided RAI ablation. This is consequent to over-reliance on short-term studies, under-appreciation of the value of RAI remnant ablation, and inflation of the side effects of RAI therapy. A balanced assessment of all of these issues provides justification to utilize post-surgical radioiodine ablation, even in cases that are considered low risk on the basis of surgical findings.
64 schema:genre research_article
65 schema:inLanguage en
66 schema:isAccessibleForFree false
67 schema:isPartOf N4446cf2cfb2046bca73c630a98fb7b71
68 N485665ba74914263bebcedff9383ecc3
69 sg:journal.1112251
70 schema:name Radioiodine-remnant ablation in low-risk differentiated thyroid cancer: pros
71 schema:pagination 61-66
72 schema:productId N0722f75664d54785b74e9656c04cf9ec
73 N0f88e44951314b379571bc26d9886f70
74 N13ca2054481c45ba88c9982e6e87e64f
75 N2b91f9b544b54aeb9f878c66c81a2e95
76 Nea332bc04a56444f88f56ca89b44454a
77 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027861444
78 https://doi.org/10.1007/s12020-015-0668-9
79 schema:sdDatePublished 2019-04-11T02:08
80 schema:sdLicense https://scigraph.springernature.com/explorer/license/
81 schema:sdPublisher N6a245065bd414b859dfa519f7d2b73c6
82 schema:url http://link.springer.com/10.1007%2Fs12020-015-0668-9
83 sgo:license sg:explorer/license/
84 sgo:sdDataset articles
85 rdf:type schema:ScholarlyArticle
86 N0722f75664d54785b74e9656c04cf9ec schema:name dimensions_id
87 schema:value pub.1027861444
88 rdf:type schema:PropertyValue
89 N0f88e44951314b379571bc26d9886f70 schema:name nlm_unique_id
90 schema:value 9434444
91 rdf:type schema:PropertyValue
92 N13ca2054481c45ba88c9982e6e87e64f schema:name pubmed_id
93 schema:value 26109472
94 rdf:type schema:PropertyValue
95 N2440305e81c64ebf868b0c2ce674f2c2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
96 schema:name Humans
97 rdf:type schema:DefinedTerm
98 N2b91f9b544b54aeb9f878c66c81a2e95 schema:name readcube_id
99 schema:value 84b91a07e7a2640ab9d245804bee5a492651e4efb2c991e2e3a5c1d49e0918e8
100 rdf:type schema:PropertyValue
101 N4446cf2cfb2046bca73c630a98fb7b71 schema:volumeNumber 50
102 rdf:type schema:PublicationVolume
103 N485665ba74914263bebcedff9383ecc3 schema:issueNumber 1
104 rdf:type schema:PublicationIssue
105 N5240bbecc5bb480b9e4074e1b9561ebd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
106 schema:name Neoplasm, Residual
107 rdf:type schema:DefinedTerm
108 N6a245065bd414b859dfa519f7d2b73c6 schema:name Springer Nature - SN SciGraph project
109 rdf:type schema:Organization
110 N8187459331cb48b3a87d8f77f40687ab schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
111 schema:name Iodine Radioisotopes
112 rdf:type schema:DefinedTerm
113 N9f7ee0bd89454564b7cc4babfb056423 rdf:first sg:person.01125651276.60
114 rdf:rest rdf:nil
115 Nea332bc04a56444f88f56ca89b44454a schema:name doi
116 schema:value 10.1007/s12020-015-0668-9
117 rdf:type schema:PropertyValue
118 Nf4b163622c194cc7a3f2f8fe65a41cb5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
119 schema:name Thyroid Neoplasms
120 rdf:type schema:DefinedTerm
121 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
122 schema:name Medical and Health Sciences
123 rdf:type schema:DefinedTerm
124 anzsrc-for:1102 schema:inDefinedTermSet anzsrc-for:
125 schema:name Cardiorespiratory Medicine and Haematology
126 rdf:type schema:DefinedTerm
127 sg:journal.1112251 schema:issn 1355-008X
128 1559-0100
129 schema:name Endocrine
130 rdf:type schema:Periodical
131 sg:person.01125651276.60 schema:affiliation https://www.grid.ac/institutes/grid.413837.a
132 schema:familyName Ain
133 schema:givenName Kenneth B.
134 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01125651276.60
135 rdf:type schema:Person
136 sg:pub.10.1007/1-4020-8107-3_20 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030092559
137 https://doi.org/10.1007/1-4020-8107-3_20
138 rdf:type schema:CreativeWork
139 sg:pub.10.1007/978-1-4419-0857-5_1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036124131
140 https://doi.org/10.1007/978-1-4419-0857-5_1
141 rdf:type schema:CreativeWork
142 sg:pub.10.1007/s10620-009-1009-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032607189
143 https://doi.org/10.1007/s10620-009-1009-8
144 rdf:type schema:CreativeWork
145 sg:pub.10.1007/s10654-014-9971-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004882245
146 https://doi.org/10.1007/s10654-014-9971-7
147 rdf:type schema:CreativeWork
148 sg:pub.10.1038/nrendo.2011.142 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021894967
149 https://doi.org/10.1038/nrendo.2011.142
150 rdf:type schema:CreativeWork
151 sg:pub.10.1207/s15324796abm3101_8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064220551
152 https://doi.org/10.1207/s15324796abm3101_8
153 rdf:type schema:CreativeWork
154 https://doi.org/10.1001/archsurg.141.5.489 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011670604
155 rdf:type schema:CreativeWork
156 https://doi.org/10.1001/jama.287.5.622 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045570425
157 rdf:type schema:CreativeWork
158 https://doi.org/10.1002/jso.23345 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039761838
159 rdf:type schema:CreativeWork
160 https://doi.org/10.1016/0002-9343(94)90321-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036476235
161 rdf:type schema:CreativeWork
162 https://doi.org/10.1016/0167-8140(89)90006-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049870733
163 rdf:type schema:CreativeWork
164 https://doi.org/10.1016/0360-3016(85)90126-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005115134
165 rdf:type schema:CreativeWork
166 https://doi.org/10.1016/j.amjmed.2009.08.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017765770
167 rdf:type schema:CreativeWork
168 https://doi.org/10.1016/j.canlet.2013.09.018 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025557391
169 rdf:type schema:CreativeWork
170 https://doi.org/10.1016/j.cll.2004.01.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009966218
171 rdf:type schema:CreativeWork
172 https://doi.org/10.1016/j.clon.2010.05.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005584603
173 rdf:type schema:CreativeWork
174 https://doi.org/10.1016/j.ecl.2008.02.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001831490
175 rdf:type schema:CreativeWork
176 https://doi.org/10.1016/j.surg.2012.02.015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036450307
177 rdf:type schema:CreativeWork
178 https://doi.org/10.1046/j.1365-2265.2002.t01-1-01545.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1032611536
179 rdf:type schema:CreativeWork
180 https://doi.org/10.1056/nejmoa1209288 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053356019
181 rdf:type schema:CreativeWork
182 https://doi.org/10.1086/606060 schema:sameAs https://app.dimensions.ai/details/publication/pub.1058810527
183 rdf:type schema:CreativeWork
184 https://doi.org/10.1089/105072503321582060 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059204488
185 rdf:type schema:CreativeWork
186 https://doi.org/10.1089/thy.2008.0392 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059320438
187 rdf:type schema:CreativeWork
188 https://doi.org/10.1089/thy.2009.0110 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018764357
189 rdf:type schema:CreativeWork
190 https://doi.org/10.1089/thy.2009.1611 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059320748
191 rdf:type schema:CreativeWork
192 https://doi.org/10.1089/thy.2011.0522 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059321320
193 rdf:type schema:CreativeWork
194 https://doi.org/10.1089/thy.2012.0043 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059321414
195 rdf:type schema:CreativeWork
196 https://doi.org/10.1089/thy.2012.0422 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059321528
197 rdf:type schema:CreativeWork
198 https://doi.org/10.1089/thy.2013.0011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059321655
199 rdf:type schema:CreativeWork
200 https://doi.org/10.1089/thy.2014.0162 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007997021
201 rdf:type schema:CreativeWork
202 https://doi.org/10.1093/annonc/mdu225 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051908923
203 rdf:type schema:CreativeWork
204 https://doi.org/10.1093/jnci/dji140 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013363968
205 rdf:type schema:CreativeWork
206 https://doi.org/10.1097/ta.0b013e3181848caa schema:sameAs https://app.dimensions.ai/details/publication/pub.1016432658
207 rdf:type schema:CreativeWork
208 https://doi.org/10.1111/j.0272-4332.2004.00433.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1006009888
209 rdf:type schema:CreativeWork
210 https://doi.org/10.1111/j.1365-2265.2008.03222.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1050098322
211 rdf:type schema:CreativeWork
212 https://doi.org/10.1111/j.1365-2265.2012.04342.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1024695976
213 rdf:type schema:CreativeWork
214 https://doi.org/10.1159/000204465 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012167905
215 rdf:type schema:CreativeWork
216 https://doi.org/10.1210/jc.2004-0739 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064287859
217 rdf:type schema:CreativeWork
218 https://doi.org/10.1210/jc.2004-0920 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064287910
219 rdf:type schema:CreativeWork
220 https://doi.org/10.1210/jc.2005-1322 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064288644
221 rdf:type schema:CreativeWork
222 https://doi.org/10.1210/jc.2005-2838 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064289036
223 rdf:type schema:CreativeWork
224 https://doi.org/10.1210/jc.2008-1931 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064290978
225 rdf:type schema:CreativeWork
226 https://doi.org/10.1210/jc.2012-3630 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064293962
227 rdf:type schema:CreativeWork
228 https://doi.org/10.1210/jc.2014-1631 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064295105
229 rdf:type schema:CreativeWork
230 https://doi.org/10.1210/jc.84.7.2449 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064300883
231 rdf:type schema:CreativeWork
232 https://doi.org/10.1210/jcem.78.3.8126134 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064318598
233 rdf:type schema:CreativeWork
234 https://doi.org/10.1210/jcem.84.11.6115 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064322264
235 rdf:type schema:CreativeWork
236 https://doi.org/10.1210/jcem.86.4.7407 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064324318
237 rdf:type schema:CreativeWork
238 https://doi.org/10.1530/erc-14-0286 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052526496
239 rdf:type schema:CreativeWork
240 https://doi.org/10.1667/rr13849.1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027176828
241 rdf:type schema:CreativeWork
242 https://doi.org/10.1677/erc.1.01320 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053545082
243 rdf:type schema:CreativeWork
244 https://doi.org/10.2217/ije.14.24 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019443110
245 rdf:type schema:CreativeWork
246 https://doi.org/10.3349/ymj.2009.50.6.744 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052278552
247 rdf:type schema:CreativeWork
248 https://www.grid.ac/institutes/grid.413837.a schema:alternateName Lexington VA Medical Center
249 schema:name Thyroid Cancer Research Laboratory, Veterans Affairs Medical Center, Lexington, KY, USA
250 Thyroid Oncology Program, Markey Cancer Center, University of Kentucky, 800 Rose Street, 40536, Lexington, KY, USA
251 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...