Cutaneous and Mucosal Manifestations of Sjögren’s Syndrome View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2017-12

AUTHORS

Elena Generali, Antonio Costanzo, Carlo Mainetti, Carlo Selmi

ABSTRACT

Sjögren's syndrome is currently considered an "autoimmune epithelitis," as exocrine glands, especially salivary and lacrimal, are progressively destructed by an immune-mediated process associated with specific serum autoantibodies and local lymphocyte infiltrate. Xerostomia remains a key complain in patients with Sjögren's syndrome but should be evaluated also for other causes such as xerogenic medications, followed by radiation and chemotherapy for head and neck cancers, hormone disorders, infections, or other connective tissue diseases. Further, xerophtalmia (also known as dry eye) frequently associated with keratoconjunctivitis sicca cumulatively affects approximately 10-30% of the general population with increasing incidence with age and is more frequently secondary to non-autoimmune diseases. On the other hand, numerous patients with Sjögren's syndrome manifest signs of systemic dryness involving the nose, the trachea, the vagina, and the skin, suggesting that other glands are also affected beyond the exocrine epithelia. Skin involvement in Sjögren's syndrome is relatively common, and various manifestations may be present, in particular xeroderma, eyelid dermatitis, annular erythema, and cutaneous vasculitis. Additional skin non-vasculitic manifestations include livedo reticularis which may occur in the absence of vasculitis, and localized nodular cutaneous amyloidosis possibly representing lymphoproliferative diseases related to Sjögren's syndrome. The treatment of skin and mucosal manifestations in Sjögren's syndrome is similar regardless of the cause, starting from patient education to avoid alcohol and tobacco smoking and to pursue dental hygiene. In conclusion, a strict collaboration between the dermatologist and the rheumatologist is essential in the adequate management of Sjögren's syndrome skin and mucosal manifestations. More... »

PAGES

357-370

References to SciGraph publications

  • 2005-02. Epithelial cells as phagocytes: apoptotic epithelial cells are engulfed by mammary alveolar epithelial cells and repress inflammatory mediator release in CELL DEATH & DIFFERENTIATION
  • 2017-05. Criteria sets for primary Sjogren’s syndrome are not adequate for those presenting with extraglandular organ involvements as their dominant clinical features in RHEUMATOLOGY INTERNATIONAL
  • 2017-12. Is hydroxychloroquine effective in treating primary Sjogren’s syndrome: a systematic review and meta-analysis in BMC MUSCULOSKELETAL DISORDERS
  • 2015-12. Current Approach to Dry Eye Disease in CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY
  • 2016-12. Epidemiology of Sjögren’s Syndrome—from an Oral Perspective in CURRENT ORAL HEALTH REPORTS
  • 2015-06. The Coexistence of Sjögren's Syndrome and Primary Biliary Cirrhosis: A Comprehensive Review in CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY
  • 2015-12. Ocular Involvement in Systemic Autoimmune Diseases in CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY
  • 2017-10. Lymphocytes as Biomarkers of Therapeutic Response in Rheumatic Autoimmune Diseases, Is It a Realistic Goal? in CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY
  • 1983-05. Cutaneous Manifestations of Primary Sjögren's Syndrome: A Reflection of Vasculitis and Association with Anti-RO(SSA) Antibodies in JOURNAL OF INVESTIGATIVE DERMATOLOGY
  • 2014-12. The role and treatment of inflammation in dry eye disease in INTERNATIONAL OPHTHALMOLOGY
  • 2005-05. Association Between Circulating Levels of the Novel TNF Family Members APRIL and BAFF and Lymphoid Organization in Primary Sjögren’s Syndrome in JOURNAL OF CLINICAL IMMUNOLOGY
  • 2015-12. The Differential Diagnosis of Dry Eyes, Dry Mouth, and Parotidomegaly: A Comprehensive Review in CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s12016-017-8639-y

    DOI

    http://dx.doi.org/10.1007/s12016-017-8639-y

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1091477820

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/28871434


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1107", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Immunology", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Medical and Health Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Autoimmunity", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Eye", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Humans", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Lacrimal Apparatus", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Mucous Membrane", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Salivary Glands", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Sjogren's Syndrome", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Skin", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Xerophthalmia", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Xerostomia", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Humanitas Research Hospital", 
              "id": "https://www.grid.ac/institutes/grid.417728.f", 
              "name": [
                "Division of Rheumatology and Clinical Immunology, Humanitas Research Hospital, Via A. Manzoni 56, 20089 Rozzano, Milan, Italy"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Generali", 
            "givenName": "Elena", 
            "id": "sg:person.01304066345.44", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01304066345.44"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Humanitas University", 
              "id": "https://www.grid.ac/institutes/grid.452490.e", 
              "name": [
                "Division of Dermatology, Humanitas Research Hospital, Rozzano, Milan, Italy", 
                "Humanitas University, Rozzano, Milan, Italy"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Costanzo", 
            "givenName": "Antonio", 
            "id": "sg:person.0577065706.51", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0577065706.51"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Dermatologia Ente Ospedaliero Cantonale, Ospedale Regionale Bellinzona, Bellinzona, Switzerland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Mainetti", 
            "givenName": "Carlo", 
            "id": "sg:person.0671637357.98", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0671637357.98"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Milan", 
              "id": "https://www.grid.ac/institutes/grid.4708.b", 
              "name": [
                "Division of Rheumatology and Clinical Immunology, Humanitas Research Hospital, Via A. Manzoni 56, 20089 Rozzano, Milan, Italy", 
                "BIOMETRA Department, University of Milan, Milan, Italy"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Selmi", 
            "givenName": "Carlo", 
            "id": "sg:person.014502337657.50", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014502337657.50"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "https://doi.org/10.1136/annrheumdis-2012-202293", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000692092"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1001/jama.2010.1014", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000708748"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1136/annrheumdis-2013-204634", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001386042"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1001/archinte.159.2.174", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002065381"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1046/j.1365-3083.2002.01072_79.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002766787"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1136/ard.2010.143743", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003044413"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/meg.0b013e328350f95b", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003701903"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/meg.0b013e328350f95b", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003701903"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/meg.0b013e328350f95b", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003701903"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jaut.2012.05.007", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003873056"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jaut.2015.12.002", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005433524"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jaut.2012.05.011", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005643229"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jaut.2014.02.008", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006860379"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.12659/msm.891364", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009874382"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jaut.2015.04.004", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010482815"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s12016-014-8431-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010571127", 
              "https://doi.org/10.1007/s12016-014-8431-1"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s12016-014-8438-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011097646", 
              "https://doi.org/10.1007/s12016-014-8438-7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0168-8278(92)90024-j", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011124957"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.autrev.2015.04.009", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011375166"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.autrev.2012.10.018", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013965358"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.coms.2013.09.009", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013978796"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1136/annrheumdis-2013-204653", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014615010"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1365-4362.1994.tb04044.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014647157"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10875-005-4091-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015517839", 
              "https://doi.org/10.1007/s10875-005-4091-5"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10875-005-4091-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015517839", 
              "https://doi.org/10.1007/s10875-005-4091-5"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1001/jama.2014.7682", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015665530"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1155/2014/781683", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016670821"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.semarthrit.2006.08.007", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018327898"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/icu.0000000000000171", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018856037"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/icu.0000000000000171", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018856037"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jtos.2014.12.006", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019088483"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jaut.2016.08.001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019595176"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3109/14397595.2016.1158773", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019743011"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jaut.2015.07.002", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020885685"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s12016-015-8471-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021313466", 
              "https://doi.org/10.1007/s12016-015-8471-1"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/0961203314546023", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021874706"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/0961203314546023", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021874706"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/0961203314546023", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021874706"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0140-6736(10)61965-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021943408"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/1346-8138.13300", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022395776"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0002-9394(00)00378-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022954709"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1136/annrheumdis-2016-210571", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025350289"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jaut.2013.02.001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026028355"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/acr.23173", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027854834"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s12016-015-8518-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027945230", 
              "https://doi.org/10.1007/s12016-015-8518-3"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1136/annrheumdis-2013-204584", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029187178"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/hep.1840200418", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033672945"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jaut.2011.11.005", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034310267"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jaut.2012.05.014", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034348979"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jaut.2012.05.008", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034420864"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.clindermatol.2013.05.035", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034758741"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jaut.2014.02.006", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034775606"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1346-8138.2002.tb00244.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034937877"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1365-2133.1995.tb02744.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034938520"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jaut.2016.06.008", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035217368"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/icu.0000000000000169", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035355899"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/icu.0000000000000169", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035355899"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1046/j.1365-2796.1996.482818000.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035368957"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.4137/oed.s16067", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035413063"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jaut.2014.08.004", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035553454"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1399-0039.1975.tb00653.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036512099"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1136/ard.58.7.423", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036972720"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jdermsci.2005.01.017", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036991619"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/bor.0000000000000346", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037436780"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/bor.0000000000000346", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037436780"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/14651858.cd008934.pub2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037886831"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jaut.2016.05.013", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038292562"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1136/ard.2010.144782", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039692445"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jaut.2015.11.002", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041200918"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jaut.2014.11.006", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042473013"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1006/clin.1998.4556", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045249735"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s40496-016-0112-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045895847", 
              "https://doi.org/10.1007/s40496-016-0112-0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s40496-016-0112-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045895847", 
              "https://doi.org/10.1007/s40496-016-0112-0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.autrev.2014.01.027", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045928496"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/art.39859", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045962772"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/art.27314", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046500491"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/art.27314", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046500491"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.rdc.2008.08.009", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046995997"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/art.23617", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047231352"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.cdd.4401517", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047825929", 
              "https://doi.org/10.1038/sj.cdd.4401517"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.cdd.4401517", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047825929", 
              "https://doi.org/10.1038/sj.cdd.4401517"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/01.md.0000119465.24818.98", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048073376"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/01.md.0000119465.24818.98", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048073376"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10792-014-9969-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048729233", 
              "https://doi.org/10.1007/s10792-014-9969-x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jaut.2016.03.003", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049371453"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jaut.2013.12.010", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050838477"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1111/1523-1747.ep12552002", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050953418", 
              "https://doi.org/10.1111/1523-1747.ep12552002"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jaut.2013.10.002", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052101986"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/iop.0000000000000723", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052472065"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/iop.0000000000000723", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052472065"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.berh.2016.04.003", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052673281"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.autrev.2016.03.004", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052809981"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.autrev.2010.05.006", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053016005"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jaut.2012.05.019", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053047344"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jaut.2013.11.001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053089725"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/cei.12869", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053610192"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1159/000446780", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053629849"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1155/2017/4768408", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053825457"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/rheumatology/kev200", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060012565"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/rheumatology/kev257", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060012595"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/rheumatology/kew194", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060012791"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/0009922807301945", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1063560937"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/0009922807301945", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1063560937"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/1759720x10363246", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064077445"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/1759720x10363246", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064077445"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2310/7750.2010.09033", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1070717883"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2310/7750.2010.09033", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1070717883"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.5114/pdia.2016.57764", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1072591086"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.7326/m13-1085", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1073742114"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1074856162", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1076794683", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1076806337", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1078982518", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1080532564", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1082499155", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1082996629", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1083131958", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1083266596", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/art.40093", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1084008856"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00296-017-3691-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1084020660", 
              "https://doi.org/10.1007/s00296-017-3691-8"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00296-017-3691-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1084020660", 
              "https://doi.org/10.1007/s00296-017-3691-8"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jaut.2017.02.005", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1084085155"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jaut.2017.03.008", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1084085165"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.7150/ijms.17718", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1084480859"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.clim.2017.03.017", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1084524685"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jaut.2017.03.012", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1084527589"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.clim.2017.04.005", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1084861590"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.clim.2017.04.018", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1085118565"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jaut.2017.05.001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1085150428"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s12891-017-1543-z", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1085378630", 
              "https://doi.org/10.1186/s12891-017-1543-z"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s12891-017-1543-z", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1085378630", 
              "https://doi.org/10.1186/s12891-017-1543-z"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2147/ppa.s132751", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1085395343"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3899/jrheum.161465", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1085468057"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s12016-017-8614-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1085711808", 
              "https://doi.org/10.1007/s12016-017-8614-7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s12016-017-8614-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1085711808", 
              "https://doi.org/10.1007/s12016-017-8614-7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jaut.2017.06.001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1086043153"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3390/jcm6070065", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1090351073"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.autrev.2017.07.012", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1090579393"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2017-12", 
        "datePublishedReg": "2017-12-01", 
        "description": "Sj\u00f6gren's syndrome is currently considered an \"autoimmune epithelitis,\" as exocrine glands, especially salivary and lacrimal, are progressively destructed by an immune-mediated process associated with specific serum autoantibodies and local lymphocyte infiltrate. Xerostomia remains a key complain in patients with Sj\u00f6gren's syndrome but should be evaluated also for other causes such as xerogenic medications, followed by radiation and chemotherapy for head and neck cancers, hormone disorders, infections, or other connective tissue diseases. Further, xerophtalmia (also known as dry eye) frequently associated with keratoconjunctivitis sicca cumulatively affects approximately 10-30% of the general population with increasing incidence with age and is more frequently secondary to non-autoimmune diseases. On the other hand, numerous patients with Sj\u00f6gren's syndrome manifest signs of systemic dryness involving the nose, the trachea, the vagina, and the skin, suggesting that other glands are also affected beyond the exocrine epithelia. Skin involvement in Sj\u00f6gren's syndrome is relatively common, and various manifestations may be present, in particular xeroderma, eyelid dermatitis, annular erythema, and cutaneous vasculitis. Additional skin non-vasculitic manifestations include livedo reticularis which may occur in the absence of vasculitis, and localized nodular cutaneous amyloidosis possibly representing lymphoproliferative diseases related to Sj\u00f6gren's syndrome. The treatment of skin and mucosal manifestations in Sj\u00f6gren's syndrome is similar regardless of the cause, starting from patient education to avoid alcohol and tobacco smoking and to pursue dental hygiene. In conclusion, a strict collaboration between the dermatologist and the rheumatologist is essential in the adequate management of Sj\u00f6gren's syndrome skin and mucosal manifestations.", 
        "genre": "research_article", 
        "id": "sg:pub.10.1007/s12016-017-8639-y", 
        "inLanguage": [
          "en"
        ], 
        "isAccessibleForFree": false, 
        "isPartOf": [
          {
            "id": "sg:journal.1094155", 
            "issn": [
              "1080-0549", 
              "1559-0267"
            ], 
            "name": "Clinical Reviews in Allergy & Immunology", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "3", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "53"
          }
        ], 
        "name": "Cutaneous and Mucosal Manifestations of Sj\u00f6gren\u2019s Syndrome", 
        "pagination": "357-370", 
        "productId": [
          {
            "name": "readcube_id", 
            "type": "PropertyValue", 
            "value": [
              "6c18c97fcd68e5e7c1127abc3ae3627823a5c6494a082974b99cf55591f5e2d6"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "28871434"
            ]
          }, 
          {
            "name": "nlm_unique_id", 
            "type": "PropertyValue", 
            "value": [
              "9504368"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1007/s12016-017-8639-y"
            ]
          }, 
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1091477820"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1007/s12016-017-8639-y", 
          "https://app.dimensions.ai/details/publication/pub.1091477820"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2019-04-11T09:55", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000347_0000000347/records_89801_00000003.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://link.springer.com/10.1007%2Fs12016-017-8639-y"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s12016-017-8639-y'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s12016-017-8639-y'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s12016-017-8639-y'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s12016-017-8639-y'


     

    This table displays all metadata directly associated to this object as RDF triples.

    500 TRIPLES      21 PREDICATES      158 URIs      31 LITERALS      19 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1007/s12016-017-8639-y schema:about N0c4ac87901744ac9b6be4746969a0e69
    2 N13617a916d7d407992901071220cf0b4
    3 N24ac30229a964239a1e53ad3baf9c33a
    4 N24ee1c3d932c464da610c3410718fa4b
    5 N3ab4bb1e99ea4c55b08ca7fb0703cc0b
    6 N7ff8825b79b14b3b9b30850200a4197a
    7 Na173e73f3d744e50ba6e08add51c42e2
    8 Nc188fe37a9d34ac289e3e4d7ef185554
    9 Necc022434ad546d696ed9d932cd68022
    10 Nef9e19e0150a472a971ccd3d842613d2
    11 anzsrc-for:11
    12 anzsrc-for:1107
    13 schema:author N07c4d1d8177945ddab19d38539cf878f
    14 schema:citation sg:pub.10.1007/s00296-017-3691-8
    15 sg:pub.10.1007/s10792-014-9969-x
    16 sg:pub.10.1007/s10875-005-4091-5
    17 sg:pub.10.1007/s12016-014-8431-1
    18 sg:pub.10.1007/s12016-014-8438-7
    19 sg:pub.10.1007/s12016-015-8471-1
    20 sg:pub.10.1007/s12016-015-8518-3
    21 sg:pub.10.1007/s12016-017-8614-7
    22 sg:pub.10.1007/s40496-016-0112-0
    23 sg:pub.10.1038/sj.cdd.4401517
    24 sg:pub.10.1111/1523-1747.ep12552002
    25 sg:pub.10.1186/s12891-017-1543-z
    26 https://app.dimensions.ai/details/publication/pub.1074856162
    27 https://app.dimensions.ai/details/publication/pub.1076794683
    28 https://app.dimensions.ai/details/publication/pub.1076806337
    29 https://app.dimensions.ai/details/publication/pub.1078982518
    30 https://app.dimensions.ai/details/publication/pub.1080532564
    31 https://app.dimensions.ai/details/publication/pub.1082499155
    32 https://app.dimensions.ai/details/publication/pub.1082996629
    33 https://app.dimensions.ai/details/publication/pub.1083131958
    34 https://app.dimensions.ai/details/publication/pub.1083266596
    35 https://doi.org/10.1001/archinte.159.2.174
    36 https://doi.org/10.1001/jama.2010.1014
    37 https://doi.org/10.1001/jama.2014.7682
    38 https://doi.org/10.1002/14651858.cd008934.pub2
    39 https://doi.org/10.1002/acr.23173
    40 https://doi.org/10.1002/art.23617
    41 https://doi.org/10.1002/art.27314
    42 https://doi.org/10.1002/art.39859
    43 https://doi.org/10.1002/art.40093
    44 https://doi.org/10.1002/hep.1840200418
    45 https://doi.org/10.1006/clin.1998.4556
    46 https://doi.org/10.1016/0168-8278(92)90024-j
    47 https://doi.org/10.1016/j.autrev.2010.05.006
    48 https://doi.org/10.1016/j.autrev.2012.10.018
    49 https://doi.org/10.1016/j.autrev.2014.01.027
    50 https://doi.org/10.1016/j.autrev.2015.04.009
    51 https://doi.org/10.1016/j.autrev.2016.03.004
    52 https://doi.org/10.1016/j.autrev.2017.07.012
    53 https://doi.org/10.1016/j.berh.2016.04.003
    54 https://doi.org/10.1016/j.clim.2017.03.017
    55 https://doi.org/10.1016/j.clim.2017.04.005
    56 https://doi.org/10.1016/j.clim.2017.04.018
    57 https://doi.org/10.1016/j.clindermatol.2013.05.035
    58 https://doi.org/10.1016/j.coms.2013.09.009
    59 https://doi.org/10.1016/j.jaut.2011.11.005
    60 https://doi.org/10.1016/j.jaut.2012.05.007
    61 https://doi.org/10.1016/j.jaut.2012.05.008
    62 https://doi.org/10.1016/j.jaut.2012.05.011
    63 https://doi.org/10.1016/j.jaut.2012.05.014
    64 https://doi.org/10.1016/j.jaut.2012.05.019
    65 https://doi.org/10.1016/j.jaut.2013.02.001
    66 https://doi.org/10.1016/j.jaut.2013.10.002
    67 https://doi.org/10.1016/j.jaut.2013.11.001
    68 https://doi.org/10.1016/j.jaut.2013.12.010
    69 https://doi.org/10.1016/j.jaut.2014.02.006
    70 https://doi.org/10.1016/j.jaut.2014.02.008
    71 https://doi.org/10.1016/j.jaut.2014.08.004
    72 https://doi.org/10.1016/j.jaut.2014.11.006
    73 https://doi.org/10.1016/j.jaut.2015.04.004
    74 https://doi.org/10.1016/j.jaut.2015.07.002
    75 https://doi.org/10.1016/j.jaut.2015.11.002
    76 https://doi.org/10.1016/j.jaut.2015.12.002
    77 https://doi.org/10.1016/j.jaut.2016.03.003
    78 https://doi.org/10.1016/j.jaut.2016.05.013
    79 https://doi.org/10.1016/j.jaut.2016.06.008
    80 https://doi.org/10.1016/j.jaut.2016.08.001
    81 https://doi.org/10.1016/j.jaut.2017.02.005
    82 https://doi.org/10.1016/j.jaut.2017.03.008
    83 https://doi.org/10.1016/j.jaut.2017.03.012
    84 https://doi.org/10.1016/j.jaut.2017.05.001
    85 https://doi.org/10.1016/j.jaut.2017.06.001
    86 https://doi.org/10.1016/j.jdermsci.2005.01.017
    87 https://doi.org/10.1016/j.jtos.2014.12.006
    88 https://doi.org/10.1016/j.rdc.2008.08.009
    89 https://doi.org/10.1016/j.semarthrit.2006.08.007
    90 https://doi.org/10.1016/s0002-9394(00)00378-0
    91 https://doi.org/10.1016/s0140-6736(10)61965-4
    92 https://doi.org/10.1046/j.1365-2796.1996.482818000.x
    93 https://doi.org/10.1046/j.1365-3083.2002.01072_79.x
    94 https://doi.org/10.1093/rheumatology/kev200
    95 https://doi.org/10.1093/rheumatology/kev257
    96 https://doi.org/10.1093/rheumatology/kew194
    97 https://doi.org/10.1097/01.md.0000119465.24818.98
    98 https://doi.org/10.1097/bor.0000000000000346
    99 https://doi.org/10.1097/icu.0000000000000169
    100 https://doi.org/10.1097/icu.0000000000000171
    101 https://doi.org/10.1097/iop.0000000000000723
    102 https://doi.org/10.1097/meg.0b013e328350f95b
    103 https://doi.org/10.1111/1346-8138.13300
    104 https://doi.org/10.1111/cei.12869
    105 https://doi.org/10.1111/j.1346-8138.2002.tb00244.x
    106 https://doi.org/10.1111/j.1365-2133.1995.tb02744.x
    107 https://doi.org/10.1111/j.1365-4362.1994.tb04044.x
    108 https://doi.org/10.1111/j.1399-0039.1975.tb00653.x
    109 https://doi.org/10.1136/annrheumdis-2012-202293
    110 https://doi.org/10.1136/annrheumdis-2013-204584
    111 https://doi.org/10.1136/annrheumdis-2013-204634
    112 https://doi.org/10.1136/annrheumdis-2013-204653
    113 https://doi.org/10.1136/annrheumdis-2016-210571
    114 https://doi.org/10.1136/ard.2010.143743
    115 https://doi.org/10.1136/ard.2010.144782
    116 https://doi.org/10.1136/ard.58.7.423
    117 https://doi.org/10.1155/2014/781683
    118 https://doi.org/10.1155/2017/4768408
    119 https://doi.org/10.1159/000446780
    120 https://doi.org/10.1177/0009922807301945
    121 https://doi.org/10.1177/0961203314546023
    122 https://doi.org/10.1177/1759720x10363246
    123 https://doi.org/10.12659/msm.891364
    124 https://doi.org/10.2147/ppa.s132751
    125 https://doi.org/10.2310/7750.2010.09033
    126 https://doi.org/10.3109/14397595.2016.1158773
    127 https://doi.org/10.3390/jcm6070065
    128 https://doi.org/10.3899/jrheum.161465
    129 https://doi.org/10.4137/oed.s16067
    130 https://doi.org/10.5114/pdia.2016.57764
    131 https://doi.org/10.7150/ijms.17718
    132 https://doi.org/10.7326/m13-1085
    133 schema:datePublished 2017-12
    134 schema:datePublishedReg 2017-12-01
    135 schema:description Sjögren's syndrome is currently considered an "autoimmune epithelitis," as exocrine glands, especially salivary and lacrimal, are progressively destructed by an immune-mediated process associated with specific serum autoantibodies and local lymphocyte infiltrate. Xerostomia remains a key complain in patients with Sjögren's syndrome but should be evaluated also for other causes such as xerogenic medications, followed by radiation and chemotherapy for head and neck cancers, hormone disorders, infections, or other connective tissue diseases. Further, xerophtalmia (also known as dry eye) frequently associated with keratoconjunctivitis sicca cumulatively affects approximately 10-30% of the general population with increasing incidence with age and is more frequently secondary to non-autoimmune diseases. On the other hand, numerous patients with Sjögren's syndrome manifest signs of systemic dryness involving the nose, the trachea, the vagina, and the skin, suggesting that other glands are also affected beyond the exocrine epithelia. Skin involvement in Sjögren's syndrome is relatively common, and various manifestations may be present, in particular xeroderma, eyelid dermatitis, annular erythema, and cutaneous vasculitis. Additional skin non-vasculitic manifestations include livedo reticularis which may occur in the absence of vasculitis, and localized nodular cutaneous amyloidosis possibly representing lymphoproliferative diseases related to Sjögren's syndrome. The treatment of skin and mucosal manifestations in Sjögren's syndrome is similar regardless of the cause, starting from patient education to avoid alcohol and tobacco smoking and to pursue dental hygiene. In conclusion, a strict collaboration between the dermatologist and the rheumatologist is essential in the adequate management of Sjögren's syndrome skin and mucosal manifestations.
    136 schema:genre research_article
    137 schema:inLanguage en
    138 schema:isAccessibleForFree false
    139 schema:isPartOf N97bdce9a24fd43ebb026630370434b99
    140 N9da08a9dbf4144d08f53e2b75ed43fdb
    141 sg:journal.1094155
    142 schema:name Cutaneous and Mucosal Manifestations of Sjögren’s Syndrome
    143 schema:pagination 357-370
    144 schema:productId N3ef8771f94664df2a33378e2f29b8750
    145 N4ff5dd8328884b6da9f9faf4d514b93f
    146 N6893ce8326224518ba3e11e76127a32a
    147 N6fde78fbb6304829ac34432799fb1658
    148 Nd928827f583742e5a1536ac05f21ea21
    149 schema:sameAs https://app.dimensions.ai/details/publication/pub.1091477820
    150 https://doi.org/10.1007/s12016-017-8639-y
    151 schema:sdDatePublished 2019-04-11T09:55
    152 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    153 schema:sdPublisher Nd0d54a5bdb4d4e98b2535545585b75b9
    154 schema:url https://link.springer.com/10.1007%2Fs12016-017-8639-y
    155 sgo:license sg:explorer/license/
    156 sgo:sdDataset articles
    157 rdf:type schema:ScholarlyArticle
    158 N07c4d1d8177945ddab19d38539cf878f rdf:first sg:person.01304066345.44
    159 rdf:rest N11b5d845d72342d18f8fa586d7b174f9
    160 N0c4ac87901744ac9b6be4746969a0e69 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    161 schema:name Xerophthalmia
    162 rdf:type schema:DefinedTerm
    163 N11b5d845d72342d18f8fa586d7b174f9 rdf:first sg:person.0577065706.51
    164 rdf:rest N34a0a6b3edc24d43976347de4d0ae6dd
    165 N13617a916d7d407992901071220cf0b4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    166 schema:name Autoimmunity
    167 rdf:type schema:DefinedTerm
    168 N24ac30229a964239a1e53ad3baf9c33a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    169 schema:name Lacrimal Apparatus
    170 rdf:type schema:DefinedTerm
    171 N24ee1c3d932c464da610c3410718fa4b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    172 schema:name Salivary Glands
    173 rdf:type schema:DefinedTerm
    174 N254f9751f5044eca992cf8a756355002 rdf:first sg:person.014502337657.50
    175 rdf:rest rdf:nil
    176 N34a0a6b3edc24d43976347de4d0ae6dd rdf:first sg:person.0671637357.98
    177 rdf:rest N254f9751f5044eca992cf8a756355002
    178 N3ab4bb1e99ea4c55b08ca7fb0703cc0b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    179 schema:name Humans
    180 rdf:type schema:DefinedTerm
    181 N3ef8771f94664df2a33378e2f29b8750 schema:name pubmed_id
    182 schema:value 28871434
    183 rdf:type schema:PropertyValue
    184 N4ff5dd8328884b6da9f9faf4d514b93f schema:name dimensions_id
    185 schema:value pub.1091477820
    186 rdf:type schema:PropertyValue
    187 N6893ce8326224518ba3e11e76127a32a schema:name doi
    188 schema:value 10.1007/s12016-017-8639-y
    189 rdf:type schema:PropertyValue
    190 N6fde78fbb6304829ac34432799fb1658 schema:name nlm_unique_id
    191 schema:value 9504368
    192 rdf:type schema:PropertyValue
    193 N7ff8825b79b14b3b9b30850200a4197a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    194 schema:name Mucous Membrane
    195 rdf:type schema:DefinedTerm
    196 N97bdce9a24fd43ebb026630370434b99 schema:volumeNumber 53
    197 rdf:type schema:PublicationVolume
    198 N9da08a9dbf4144d08f53e2b75ed43fdb schema:issueNumber 3
    199 rdf:type schema:PublicationIssue
    200 Na173e73f3d744e50ba6e08add51c42e2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    201 schema:name Eye
    202 rdf:type schema:DefinedTerm
    203 Nc188fe37a9d34ac289e3e4d7ef185554 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    204 schema:name Xerostomia
    205 rdf:type schema:DefinedTerm
    206 Nd0d54a5bdb4d4e98b2535545585b75b9 schema:name Springer Nature - SN SciGraph project
    207 rdf:type schema:Organization
    208 Nd928827f583742e5a1536ac05f21ea21 schema:name readcube_id
    209 schema:value 6c18c97fcd68e5e7c1127abc3ae3627823a5c6494a082974b99cf55591f5e2d6
    210 rdf:type schema:PropertyValue
    211 Ndaafc919dfea476992a338f57f7f863f schema:name Dermatologia Ente Ospedaliero Cantonale, Ospedale Regionale Bellinzona, Bellinzona, Switzerland
    212 rdf:type schema:Organization
    213 Necc022434ad546d696ed9d932cd68022 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    214 schema:name Sjogren's Syndrome
    215 rdf:type schema:DefinedTerm
    216 Nef9e19e0150a472a971ccd3d842613d2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    217 schema:name Skin
    218 rdf:type schema:DefinedTerm
    219 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
    220 schema:name Medical and Health Sciences
    221 rdf:type schema:DefinedTerm
    222 anzsrc-for:1107 schema:inDefinedTermSet anzsrc-for:
    223 schema:name Immunology
    224 rdf:type schema:DefinedTerm
    225 sg:journal.1094155 schema:issn 1080-0549
    226 1559-0267
    227 schema:name Clinical Reviews in Allergy & Immunology
    228 rdf:type schema:Periodical
    229 sg:person.01304066345.44 schema:affiliation https://www.grid.ac/institutes/grid.417728.f
    230 schema:familyName Generali
    231 schema:givenName Elena
    232 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01304066345.44
    233 rdf:type schema:Person
    234 sg:person.014502337657.50 schema:affiliation https://www.grid.ac/institutes/grid.4708.b
    235 schema:familyName Selmi
    236 schema:givenName Carlo
    237 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014502337657.50
    238 rdf:type schema:Person
    239 sg:person.0577065706.51 schema:affiliation https://www.grid.ac/institutes/grid.452490.e
    240 schema:familyName Costanzo
    241 schema:givenName Antonio
    242 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0577065706.51
    243 rdf:type schema:Person
    244 sg:person.0671637357.98 schema:affiliation Ndaafc919dfea476992a338f57f7f863f
    245 schema:familyName Mainetti
    246 schema:givenName Carlo
    247 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0671637357.98
    248 rdf:type schema:Person
    249 sg:pub.10.1007/s00296-017-3691-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084020660
    250 https://doi.org/10.1007/s00296-017-3691-8
    251 rdf:type schema:CreativeWork
    252 sg:pub.10.1007/s10792-014-9969-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1048729233
    253 https://doi.org/10.1007/s10792-014-9969-x
    254 rdf:type schema:CreativeWork
    255 sg:pub.10.1007/s10875-005-4091-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015517839
    256 https://doi.org/10.1007/s10875-005-4091-5
    257 rdf:type schema:CreativeWork
    258 sg:pub.10.1007/s12016-014-8431-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010571127
    259 https://doi.org/10.1007/s12016-014-8431-1
    260 rdf:type schema:CreativeWork
    261 sg:pub.10.1007/s12016-014-8438-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011097646
    262 https://doi.org/10.1007/s12016-014-8438-7
    263 rdf:type schema:CreativeWork
    264 sg:pub.10.1007/s12016-015-8471-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021313466
    265 https://doi.org/10.1007/s12016-015-8471-1
    266 rdf:type schema:CreativeWork
    267 sg:pub.10.1007/s12016-015-8518-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027945230
    268 https://doi.org/10.1007/s12016-015-8518-3
    269 rdf:type schema:CreativeWork
    270 sg:pub.10.1007/s12016-017-8614-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1085711808
    271 https://doi.org/10.1007/s12016-017-8614-7
    272 rdf:type schema:CreativeWork
    273 sg:pub.10.1007/s40496-016-0112-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045895847
    274 https://doi.org/10.1007/s40496-016-0112-0
    275 rdf:type schema:CreativeWork
    276 sg:pub.10.1038/sj.cdd.4401517 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047825929
    277 https://doi.org/10.1038/sj.cdd.4401517
    278 rdf:type schema:CreativeWork
    279 sg:pub.10.1111/1523-1747.ep12552002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050953418
    280 https://doi.org/10.1111/1523-1747.ep12552002
    281 rdf:type schema:CreativeWork
    282 sg:pub.10.1186/s12891-017-1543-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1085378630
    283 https://doi.org/10.1186/s12891-017-1543-z
    284 rdf:type schema:CreativeWork
    285 https://app.dimensions.ai/details/publication/pub.1074856162 schema:CreativeWork
    286 https://app.dimensions.ai/details/publication/pub.1076794683 schema:CreativeWork
    287 https://app.dimensions.ai/details/publication/pub.1076806337 schema:CreativeWork
    288 https://app.dimensions.ai/details/publication/pub.1078982518 schema:CreativeWork
    289 https://app.dimensions.ai/details/publication/pub.1080532564 schema:CreativeWork
    290 https://app.dimensions.ai/details/publication/pub.1082499155 schema:CreativeWork
    291 https://app.dimensions.ai/details/publication/pub.1082996629 schema:CreativeWork
    292 https://app.dimensions.ai/details/publication/pub.1083131958 schema:CreativeWork
    293 https://app.dimensions.ai/details/publication/pub.1083266596 schema:CreativeWork
    294 https://doi.org/10.1001/archinte.159.2.174 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002065381
    295 rdf:type schema:CreativeWork
    296 https://doi.org/10.1001/jama.2010.1014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000708748
    297 rdf:type schema:CreativeWork
    298 https://doi.org/10.1001/jama.2014.7682 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015665530
    299 rdf:type schema:CreativeWork
    300 https://doi.org/10.1002/14651858.cd008934.pub2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037886831
    301 rdf:type schema:CreativeWork
    302 https://doi.org/10.1002/acr.23173 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027854834
    303 rdf:type schema:CreativeWork
    304 https://doi.org/10.1002/art.23617 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047231352
    305 rdf:type schema:CreativeWork
    306 https://doi.org/10.1002/art.27314 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046500491
    307 rdf:type schema:CreativeWork
    308 https://doi.org/10.1002/art.39859 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045962772
    309 rdf:type schema:CreativeWork
    310 https://doi.org/10.1002/art.40093 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084008856
    311 rdf:type schema:CreativeWork
    312 https://doi.org/10.1002/hep.1840200418 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033672945
    313 rdf:type schema:CreativeWork
    314 https://doi.org/10.1006/clin.1998.4556 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045249735
    315 rdf:type schema:CreativeWork
    316 https://doi.org/10.1016/0168-8278(92)90024-j schema:sameAs https://app.dimensions.ai/details/publication/pub.1011124957
    317 rdf:type schema:CreativeWork
    318 https://doi.org/10.1016/j.autrev.2010.05.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053016005
    319 rdf:type schema:CreativeWork
    320 https://doi.org/10.1016/j.autrev.2012.10.018 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013965358
    321 rdf:type schema:CreativeWork
    322 https://doi.org/10.1016/j.autrev.2014.01.027 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045928496
    323 rdf:type schema:CreativeWork
    324 https://doi.org/10.1016/j.autrev.2015.04.009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011375166
    325 rdf:type schema:CreativeWork
    326 https://doi.org/10.1016/j.autrev.2016.03.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052809981
    327 rdf:type schema:CreativeWork
    328 https://doi.org/10.1016/j.autrev.2017.07.012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1090579393
    329 rdf:type schema:CreativeWork
    330 https://doi.org/10.1016/j.berh.2016.04.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052673281
    331 rdf:type schema:CreativeWork
    332 https://doi.org/10.1016/j.clim.2017.03.017 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084524685
    333 rdf:type schema:CreativeWork
    334 https://doi.org/10.1016/j.clim.2017.04.005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084861590
    335 rdf:type schema:CreativeWork
    336 https://doi.org/10.1016/j.clim.2017.04.018 schema:sameAs https://app.dimensions.ai/details/publication/pub.1085118565
    337 rdf:type schema:CreativeWork
    338 https://doi.org/10.1016/j.clindermatol.2013.05.035 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034758741
    339 rdf:type schema:CreativeWork
    340 https://doi.org/10.1016/j.coms.2013.09.009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013978796
    341 rdf:type schema:CreativeWork
    342 https://doi.org/10.1016/j.jaut.2011.11.005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034310267
    343 rdf:type schema:CreativeWork
    344 https://doi.org/10.1016/j.jaut.2012.05.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003873056
    345 rdf:type schema:CreativeWork
    346 https://doi.org/10.1016/j.jaut.2012.05.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034420864
    347 rdf:type schema:CreativeWork
    348 https://doi.org/10.1016/j.jaut.2012.05.011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005643229
    349 rdf:type schema:CreativeWork
    350 https://doi.org/10.1016/j.jaut.2012.05.014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034348979
    351 rdf:type schema:CreativeWork
    352 https://doi.org/10.1016/j.jaut.2012.05.019 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053047344
    353 rdf:type schema:CreativeWork
    354 https://doi.org/10.1016/j.jaut.2013.02.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026028355
    355 rdf:type schema:CreativeWork
    356 https://doi.org/10.1016/j.jaut.2013.10.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052101986
    357 rdf:type schema:CreativeWork
    358 https://doi.org/10.1016/j.jaut.2013.11.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053089725
    359 rdf:type schema:CreativeWork
    360 https://doi.org/10.1016/j.jaut.2013.12.010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050838477
    361 rdf:type schema:CreativeWork
    362 https://doi.org/10.1016/j.jaut.2014.02.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034775606
    363 rdf:type schema:CreativeWork
    364 https://doi.org/10.1016/j.jaut.2014.02.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006860379
    365 rdf:type schema:CreativeWork
    366 https://doi.org/10.1016/j.jaut.2014.08.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035553454
    367 rdf:type schema:CreativeWork
    368 https://doi.org/10.1016/j.jaut.2014.11.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042473013
    369 rdf:type schema:CreativeWork
    370 https://doi.org/10.1016/j.jaut.2015.04.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010482815
    371 rdf:type schema:CreativeWork
    372 https://doi.org/10.1016/j.jaut.2015.07.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020885685
    373 rdf:type schema:CreativeWork
    374 https://doi.org/10.1016/j.jaut.2015.11.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041200918
    375 rdf:type schema:CreativeWork
    376 https://doi.org/10.1016/j.jaut.2015.12.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005433524
    377 rdf:type schema:CreativeWork
    378 https://doi.org/10.1016/j.jaut.2016.03.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049371453
    379 rdf:type schema:CreativeWork
    380 https://doi.org/10.1016/j.jaut.2016.05.013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038292562
    381 rdf:type schema:CreativeWork
    382 https://doi.org/10.1016/j.jaut.2016.06.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035217368
    383 rdf:type schema:CreativeWork
    384 https://doi.org/10.1016/j.jaut.2016.08.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019595176
    385 rdf:type schema:CreativeWork
    386 https://doi.org/10.1016/j.jaut.2017.02.005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084085155
    387 rdf:type schema:CreativeWork
    388 https://doi.org/10.1016/j.jaut.2017.03.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084085165
    389 rdf:type schema:CreativeWork
    390 https://doi.org/10.1016/j.jaut.2017.03.012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084527589
    391 rdf:type schema:CreativeWork
    392 https://doi.org/10.1016/j.jaut.2017.05.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1085150428
    393 rdf:type schema:CreativeWork
    394 https://doi.org/10.1016/j.jaut.2017.06.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1086043153
    395 rdf:type schema:CreativeWork
    396 https://doi.org/10.1016/j.jdermsci.2005.01.017 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036991619
    397 rdf:type schema:CreativeWork
    398 https://doi.org/10.1016/j.jtos.2014.12.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019088483
    399 rdf:type schema:CreativeWork
    400 https://doi.org/10.1016/j.rdc.2008.08.009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046995997
    401 rdf:type schema:CreativeWork
    402 https://doi.org/10.1016/j.semarthrit.2006.08.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018327898
    403 rdf:type schema:CreativeWork
    404 https://doi.org/10.1016/s0002-9394(00)00378-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022954709
    405 rdf:type schema:CreativeWork
    406 https://doi.org/10.1016/s0140-6736(10)61965-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021943408
    407 rdf:type schema:CreativeWork
    408 https://doi.org/10.1046/j.1365-2796.1996.482818000.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1035368957
    409 rdf:type schema:CreativeWork
    410 https://doi.org/10.1046/j.1365-3083.2002.01072_79.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1002766787
    411 rdf:type schema:CreativeWork
    412 https://doi.org/10.1093/rheumatology/kev200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060012565
    413 rdf:type schema:CreativeWork
    414 https://doi.org/10.1093/rheumatology/kev257 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060012595
    415 rdf:type schema:CreativeWork
    416 https://doi.org/10.1093/rheumatology/kew194 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060012791
    417 rdf:type schema:CreativeWork
    418 https://doi.org/10.1097/01.md.0000119465.24818.98 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048073376
    419 rdf:type schema:CreativeWork
    420 https://doi.org/10.1097/bor.0000000000000346 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037436780
    421 rdf:type schema:CreativeWork
    422 https://doi.org/10.1097/icu.0000000000000169 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035355899
    423 rdf:type schema:CreativeWork
    424 https://doi.org/10.1097/icu.0000000000000171 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018856037
    425 rdf:type schema:CreativeWork
    426 https://doi.org/10.1097/iop.0000000000000723 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052472065
    427 rdf:type schema:CreativeWork
    428 https://doi.org/10.1097/meg.0b013e328350f95b schema:sameAs https://app.dimensions.ai/details/publication/pub.1003701903
    429 rdf:type schema:CreativeWork
    430 https://doi.org/10.1111/1346-8138.13300 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022395776
    431 rdf:type schema:CreativeWork
    432 https://doi.org/10.1111/cei.12869 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053610192
    433 rdf:type schema:CreativeWork
    434 https://doi.org/10.1111/j.1346-8138.2002.tb00244.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1034937877
    435 rdf:type schema:CreativeWork
    436 https://doi.org/10.1111/j.1365-2133.1995.tb02744.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1034938520
    437 rdf:type schema:CreativeWork
    438 https://doi.org/10.1111/j.1365-4362.1994.tb04044.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1014647157
    439 rdf:type schema:CreativeWork
    440 https://doi.org/10.1111/j.1399-0039.1975.tb00653.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1036512099
    441 rdf:type schema:CreativeWork
    442 https://doi.org/10.1136/annrheumdis-2012-202293 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000692092
    443 rdf:type schema:CreativeWork
    444 https://doi.org/10.1136/annrheumdis-2013-204584 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029187178
    445 rdf:type schema:CreativeWork
    446 https://doi.org/10.1136/annrheumdis-2013-204634 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001386042
    447 rdf:type schema:CreativeWork
    448 https://doi.org/10.1136/annrheumdis-2013-204653 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014615010
    449 rdf:type schema:CreativeWork
    450 https://doi.org/10.1136/annrheumdis-2016-210571 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025350289
    451 rdf:type schema:CreativeWork
    452 https://doi.org/10.1136/ard.2010.143743 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003044413
    453 rdf:type schema:CreativeWork
    454 https://doi.org/10.1136/ard.2010.144782 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039692445
    455 rdf:type schema:CreativeWork
    456 https://doi.org/10.1136/ard.58.7.423 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036972720
    457 rdf:type schema:CreativeWork
    458 https://doi.org/10.1155/2014/781683 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016670821
    459 rdf:type schema:CreativeWork
    460 https://doi.org/10.1155/2017/4768408 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053825457
    461 rdf:type schema:CreativeWork
    462 https://doi.org/10.1159/000446780 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053629849
    463 rdf:type schema:CreativeWork
    464 https://doi.org/10.1177/0009922807301945 schema:sameAs https://app.dimensions.ai/details/publication/pub.1063560937
    465 rdf:type schema:CreativeWork
    466 https://doi.org/10.1177/0961203314546023 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021874706
    467 rdf:type schema:CreativeWork
    468 https://doi.org/10.1177/1759720x10363246 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064077445
    469 rdf:type schema:CreativeWork
    470 https://doi.org/10.12659/msm.891364 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009874382
    471 rdf:type schema:CreativeWork
    472 https://doi.org/10.2147/ppa.s132751 schema:sameAs https://app.dimensions.ai/details/publication/pub.1085395343
    473 rdf:type schema:CreativeWork
    474 https://doi.org/10.2310/7750.2010.09033 schema:sameAs https://app.dimensions.ai/details/publication/pub.1070717883
    475 rdf:type schema:CreativeWork
    476 https://doi.org/10.3109/14397595.2016.1158773 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019743011
    477 rdf:type schema:CreativeWork
    478 https://doi.org/10.3390/jcm6070065 schema:sameAs https://app.dimensions.ai/details/publication/pub.1090351073
    479 rdf:type schema:CreativeWork
    480 https://doi.org/10.3899/jrheum.161465 schema:sameAs https://app.dimensions.ai/details/publication/pub.1085468057
    481 rdf:type schema:CreativeWork
    482 https://doi.org/10.4137/oed.s16067 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035413063
    483 rdf:type schema:CreativeWork
    484 https://doi.org/10.5114/pdia.2016.57764 schema:sameAs https://app.dimensions.ai/details/publication/pub.1072591086
    485 rdf:type schema:CreativeWork
    486 https://doi.org/10.7150/ijms.17718 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084480859
    487 rdf:type schema:CreativeWork
    488 https://doi.org/10.7326/m13-1085 schema:sameAs https://app.dimensions.ai/details/publication/pub.1073742114
    489 rdf:type schema:CreativeWork
    490 https://www.grid.ac/institutes/grid.417728.f schema:alternateName Humanitas Research Hospital
    491 schema:name Division of Rheumatology and Clinical Immunology, Humanitas Research Hospital, Via A. Manzoni 56, 20089 Rozzano, Milan, Italy
    492 rdf:type schema:Organization
    493 https://www.grid.ac/institutes/grid.452490.e schema:alternateName Humanitas University
    494 schema:name Division of Dermatology, Humanitas Research Hospital, Rozzano, Milan, Italy
    495 Humanitas University, Rozzano, Milan, Italy
    496 rdf:type schema:Organization
    497 https://www.grid.ac/institutes/grid.4708.b schema:alternateName University of Milan
    498 schema:name BIOMETRA Department, University of Milan, Milan, Italy
    499 Division of Rheumatology and Clinical Immunology, Humanitas Research Hospital, Via A. Manzoni 56, 20089 Rozzano, Milan, Italy
    500 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...