Effects of Titanium Dioxide Nanoparticles Exposure on Human Health—a Review View Full Text


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Article Info

DATE

2019-04-13

AUTHORS

Ewa Baranowska-Wójcik, Dominik Szwajgier, Patryk Oleszczuk, Anna Winiarska-Mieczan

ABSTRACT

Recently, an increased interest in nanotechnology applications can be observed in various fields (medicine, materials science, pharmacy, environmental protection, agriculture etc.). Due to an increasing scope of applications, the exposure of humans to nanoparticles (NPs) is inevitable. A number of studies revealed that after inhalation or oral exposure, NPs accumulate in, among other places, the lungs, alimentary tract, liver, heart, spleen, kidneys and cardiac muscle. In addition, they disturb glucose and lipid homeostasis in mice and rats. In a wide group of nanoparticles currently used on an industrial scale, titanium dioxide nanoparticles—TiO2 NPs—are particularly popular. Due to their white colour, TiO2 NPs are commonly used as a food additive (E 171). The possible risk to health after consuming food containing nanoparticles has been poorly explored but it is supposed that the toxicity of nanoparticles depends on their size, morphology, rate of migration and amount consumed. Scientific databases inform that TiO2 NPs can induce inflammation due to oxidative stress. They can also have a genotoxic effect leading to, among others, apoptosis or chromosomal instability. This paper gives a review of previous studies concerning the effects of exposure to TiO2 NPs on a living organism (human, animal). This information is necessary in order to demonstrate potential toxicity of inorganic nanoparticles on human health. More... »

PAGES

118-129

References to SciGraph publications

  • 2015. Nanotechnologies in Food and Agriculture in NONE
  • 2010-12-21. Risks from accidental exposures to engineered nanoparticles and neurological health effects: A critical review in PARTICLE AND FIBRE TOXICOLOGY
  • 2014-12-09. Titanium dioxide nanoparticles promote arrhythmias via a direct interaction with rat cardiac tissue in PARTICLE AND FIBRE TOXICOLOGY
  • 2015-11-25. Nanotechnology: a future tool to improve quality and safety in meat industry in JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
  • 2013-04-15. Titanium dioxide nanoparticles: a review of current toxicological data in PARTICLE AND FIBRE TOXICOLOGY
  • 2015-01-31. A study of the uptake and biodistribution of nano-titanium dioxide using in vitro and in vivo models of oral intake in JOURNAL OF NANOPARTICLE RESEARCH
  • 2012-09-16. Size influences the cytotoxicity of poly (lactic-co-glycolic acid) (PLGA) and titanium dioxide (TiO2) nanoparticles in ARCHIVES OF TOXICOLOGY
  • 2010-04-27. P38-Nrf-2 Signaling Pathway of Oxidative Stress in Mice Caused by Nanoparticulate TiO2 in BIOLOGICAL TRACE ELEMENT RESEARCH
  • 2013-03-26. Comparative absorption, distribution, and excretion of titanium dioxide and zinc oxide nanoparticles after repeated oral administration in PARTICLE AND FIBRE TOXICOLOGY
  • 2014-05-11. Food grade titanium dioxide disrupts intestinal brush border microvilli in vitro independent of sedimentation in CELL BIOLOGY AND TOXICOLOGY
  • 2016-06-13. Is Neurotoxicity of Metallic Nanoparticles the Cascades of Oxidative Stress? in NANOSCALE RESEARCH LETTERS
  • 2014-07-03. Tissue distribution and elimination after oral and intravenous administration of different titanium dioxide nanoparticles in rats in PARTICLE AND FIBRE TOXICOLOGY
  • 2009-10. Apoptosis induced by titanium dioxide nanoparticles in cultured murine microglia N9 cells in CHINESE SCIENCE BULLETIN (CHINESE VERSION)
  • 2014-03-25. Titanium dioxide nanoparticle impact and translocation through ex vivo, in vivo and in vitro gut epithelia in PARTICLE AND FIBRE TOXICOLOGY
  • 2015-08-14. Toxicological effect of TiO2 nanoparticle-induced myocarditis in mice in NANOSCALE RESEARCH LETTERS
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s12011-019-01706-6

    DOI

    http://dx.doi.org/10.1007/s12011-019-01706-6

    DIMENSIONS

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    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/30982201


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