Correlation of Trace Elemental Profiles in Blood Samples of Indian Patients with Leukoplakia and Oral Submucous Fibrosis View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2011-06-30

AUTHORS

J. G. Ray, Ranjan Ghosh, Debarati Mallick, Niharika Swain, Premdeep Gandhi, S. S. Ram, S. Selvaraj, A. Rathore, Sudarshan Mathummal, Anindita Chakraborty

ABSTRACT

In order to ascertain possible correlation between alterations in trace elemental profile and the progression or regression of two most common potentially malignant disorders affecting oral cavity, namely oral submucous fibrosis and leukoplakia, blood from 60 patients from each group of patients as well from 30 healthy individuals was analyzed for elemental profiling employing EDXRF technique. Out of the 16 detected elements (K, Si, Ca, V, Cr, Ni, Mn, Fe, Cu, Zn, Se, Br, Rb, Sr, Co, and Pb), Mn, Fe, Zn, Br, and Co showed remarkable alteration in their profile in both leukoplakia and oral submucous fibrosis patients with respect to the normal healthy individuals. While Zn, Br, and Fe reflected similar changes—showing gross depletion in both the diseased groups, Mn and Co depicted inverse pattern of alterations in their concentrations in the two types of precancerous disorders when compared to the control subjects. More... »

PAGES

295-305

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s12011-011-9091-0

DOI

http://dx.doi.org/10.1007/s12011-011-9091-0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1008457163

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/21717219


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