Advances in RNA Interference Technology and Its Impact on Nutritional Improvement, Disease and Insect Control in Plants View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2013-03

AUTHORS

Rajan Katoch, Neelam Thakur

ABSTRACT

This review highlights the advances in the knowledge of RNA interference (RNAi) and discusses recent progress on the functionality of different components RNAi machinery operating in the organisms. The silencing of genes by RNA interference has become the technology of choice for investigation of gene functions in different organisms. The refinement in the knowledge of the endogenous RNAi pathways in plants along with the development of new strategies and applications for the improvement of nutritional value of important agricultural crops through suppression of genes in different plants have opened new vistas for nutritional security. The improvement in the nutritional status of the plants and reduction in the level of toxins or antinutrients was desired for long, but the available technology was not completely successful in achieving the tissue specific regulation of some genes. In the recent years, a number of economically important crop plants have been tested successfully for improving plant nutritional value through metabolic engineering using RNAi. The implications of this technology for crop improvement programs, including nutritional enrichment, reduction of antinutrients, disease, and insect control have been successfully tested in variety of crops with commercial considerations. The enhancement of the nutraceutical traits for the desired health benefits in common crop plants through manipulation of gene expression has been elaborated in this article. The tremendous potential with RNAi technology is expected to revolutionize the modern agriculture for meeting the growing challenges is discussed. More... »

PAGES

1579-1605

References to SciGraph publications

  • 1997-02. Plants combat infection by gene silencing in NATURE
  • 2005-07. Fruit-specific RNAi-mediated suppression of DET1 enhances carotenoid and flavonoid content in tomatoes in NATURE BIOTECHNOLOGY
  • 2001-05. Overexpression of petunia chalcone isomerase in tomato results in fruit containing increased levels of flavonols in NATURE BIOTECHNOLOGY
  • 1991-10. Sequence of three members and expression of a new major subfamily of glutelin genes from rice in PLANT MOLECULAR BIOLOGY
  • 2007-11. Specialization and evolution of endogenous small RNA pathways in NATURE REVIEWS GENETICS
  • 2003-11. Structure and nucleic-acid binding of the Drosophila Argonaute 2 PAZ domain in NATURE
  • 2000-03. An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells in NATURE
  • 2008-02. Insect resistance to Bt crops: evidence versus theory in NATURE BIOTECHNOLOGY
  • 2007-05. The effects of spacer sequences on silencing efficiency of plant RNAi vectors in PLANT CELL REPORTS
  • 2010-04. Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model in NATURE BIOTECHNOLOGY
  • 2004-05. Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain in NATURE
  • 2003-02. RNAi targeting of DNA virus in plants in NATURE BIOTECHNOLOGY
  • 2004-01. Transforming petals into sepaloid organs in Arabidopsis and oilseed rape: implementation of the hairpin RNA-mediated gene silencing technology in an organ-specific manner in PLANTA
  • 2009-01-22. A three-dimensional view of the molecular machinery of RNA interference in NATURE
  • 1997-01. Engineering resistance against tomato yellow leaf curl virus (TYLCV) using antisense RNA in PLANT MOLECULAR BIOLOGY
  • 2005-02. Different effects on ACC oxidase gene silencing triggered by RNA interference in transgenic tomato in PLANT CELL REPORTS
  • 1998-10. Specific interference by ingested dsRNA in NATURE
  • 2004-09. Mechanisms of gene silencing by double-stranded RNA in NATURE
  • 1998-02. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans in NATURE
  • 2005-03. Structural insights into mRNA recognition from a PIWI domain–siRNA guide complex in NATURE
  • 2007-11. Silencing a cotton bollworm P450 monooxygenase gene by plant-mediated RNAi impairs larval tolerance of gossypol in NATURE BIOTECHNOLOGY
  • 2007-11. Control of coleopteran insect pests through RNA interference in NATURE BIOTECHNOLOGY
  • 1990-10. Induction of male sterility in plants by a chimaeric ribonuclease gene in NATURE
  • 2003-09. The nuclear RNase III Drosha initiates microRNA processing in NATURE
  • 2004-06. Engineering plants with increased levels of the antioxidant chlorogenic acid in NATURE BIOTECHNOLOGY
  • 2003-09. Testing the efficiency of dsRNAi constructs in vivo: A transient expression assay based on two fluorescent proteins in MOLECULAR BIOLOGY REPORTS
  • 1997-10. Systemic signalling in gene silencing in NATURE
  • 2000-10. Phytochromes and light signal perception by plants—an emerging synthesis in NATURE
  • 2007-09. RNAi and microRNA: breakthrough technologies for the improvement of plant nutritional value and metabolic engineering in METABOLOMICS
  • 2004-06. Nucleic acid 3′-end recognition by the Argonaute2 PAZ domain in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2004-04. Application of RNAi to confirm theobromine as the major intermediate for caffeine biosynthesis in coffee plants with potential for construction of decaffeinated varieties in PLANT MOLECULAR BIOLOGY
  • 2003-12. Crude extracts of bacterially expressed dsRNA can be used to protect plants against virus infections in BMC BIOTECHNOLOGY
  • 2003-12. Disruption of vitellogenin gene function in adult honeybees by intra-abdominal injection of double-stranded RNA in BMC BIOTECHNOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s12010-012-0046-5

    DOI

    http://dx.doi.org/10.1007/s12010-012-0046-5

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1031079976

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/23322250


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Genetics", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Biological Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Crops, Agricultural", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Gene Expression Regulation, Plant", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Insect Control", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Metabolic Engineering", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Nutritive Value", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Plant Proteins", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Plants", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Plants, Genetically Modified", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "RNA Interference", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Purdue University", 
              "id": "https://www.grid.ac/institutes/grid.169077.e", 
              "name": [
                "Biochemistry Laboratory, Department of Crop Improvement, College of Agriculture, CSK Himachal Pradesh Krishi Vishvavidyalaya, 176062, Palampur, India", 
                "Department of Entomology, Purdue University, 47907, West Lafayette, IN, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Katoch", 
            "givenName": "Rajan", 
            "id": "sg:person.010373015235.05", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010373015235.05"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Punjab Agricultural University", 
              "id": "https://www.grid.ac/institutes/grid.412577.2", 
              "name": [
                "Department of Biosciences, Punjab Agricultural University, 141004, Ludhiana, India"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Thakur", 
            "givenName": "Neelam", 
            "id": "sg:person.01337170554.58", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01337170554.58"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "https://doi.org/10.1101/gad.862301", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000961502"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt0203-131b", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001112654", 
              "https://doi.org/10.1038/nbt0203-131b"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt0203-131b", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001112654", 
              "https://doi.org/10.1038/nbt0203-131b"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00425-003-1117-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001560219", 
              "https://doi.org/10.1007/s00425-003-1117-1"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1745-7270.2006.00124.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004108342"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0168-1702(02)00353-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004127356"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0168-1702(02)00353-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004127356"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00299-006-0277-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004233953", 
              "https://doi.org/10.1007/s00299-006-0277-4"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00299-006-0277-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004233953", 
              "https://doi.org/10.1007/s00299-006-0277-4"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00299-006-0277-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004233953", 
              "https://doi.org/10.1007/s00299-006-0277-4"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/emboj/20.23.6877", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004775429"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0958-1669(00)00192-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005602147"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1098/rstb.2008.0168", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006247079"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.0509770102", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006641044"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1023/a:1024945920331", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006645207", 
              "https://doi.org/10.1023/a:1024945920331"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1365-2583.2010.01054.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006858786"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ibmb.2008.10.011", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007660317"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1006/jmbi.1993.1084", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007778756"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature01957", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007929702", 
              "https://doi.org/10.1038/nature01957"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature01957", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007929702", 
              "https://doi.org/10.1038/nature01957"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s1360-1385(01)02055-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008001256"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00037068", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008140582", 
              "https://doi.org/10.1007/bf00037068"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00037068", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008140582", 
              "https://doi.org/10.1007/bf00037068"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.tplants.2008.05.004", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008424940"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s11103-004-0393-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008770391", 
              "https://doi.org/10.1007/s11103-004-0393-x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1432-0436.2004.07202005.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009278115"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/pcp/pch048", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009291521"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.cell.2005.06.023", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009711015"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1080/00218839.2006.11101307", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010004387"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nsmb777", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010191056", 
              "https://doi.org/10.1038/nsmb777"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nsmb777", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010191056", 
              "https://doi.org/10.1038/nsmb777"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.0605389103", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011149301"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.sbi.2006.12.002", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012392121"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1105/tpc.2.12.1201", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013352558"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1101/gad.1026102", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014003859"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0092-8674(04)00258-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014311702"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1105/tpc.2.4.279", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014921424"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1101/gad.1187904", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015033164"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1104/pp.108.123273", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015037401"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00299-004-0887-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015503478", 
              "https://doi.org/10.1007/s00299-004-0887-7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00299-004-0887-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015503478", 
              "https://doi.org/10.1007/s00299-004-0887-7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.tibtech.2008.04.004", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015574559"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1105/tpc.003061", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016138027"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1365-313x.2005.02492.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016891838"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1365-313x.2005.02492.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016891838"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.1121638", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016990355"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1105/tpc.2.4.291", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017136927"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1472-6750-3-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018235747", 
              "https://doi.org/10.1186/1472-6750-3-1"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt1108", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018379429", 
              "https://doi.org/10.1038/nbt1108"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt1108", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018379429", 
              "https://doi.org/10.1038/nbt1108"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/35888", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018713804", 
              "https://doi.org/10.1038/35888"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/35888", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018713804", 
              "https://doi.org/10.1038/35888"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0092-8674(01)00576-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019924014"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.cell.2004.12.035", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020132624"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1467-7652.2005.00132.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020593219"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1467-7652.2005.00132.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020593219"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0092-8674(01)00547-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021383396"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1472-6750-3-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021968571", 
              "https://doi.org/10.1186/1472-6750-3-3"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature02123", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022420805", 
              "https://doi.org/10.1038/nature02123"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature02123", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022420805", 
              "https://doi.org/10.1038/nature02123"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature07755", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022586447", 
              "https://doi.org/10.1038/nature07755"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/35036500", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023274001", 
              "https://doi.org/10.1038/35036500"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/35036500", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023274001", 
              "https://doi.org/10.1038/35036500"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/27579", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023285321", 
              "https://doi.org/10.1038/27579"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/27579", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023285321", 
              "https://doi.org/10.1038/27579"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1365-2583.2008.00839.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024029729"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.cub.2004.03.008", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024046661"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1101/gad.1184404", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024436325"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.molbiopara.2006.03.013", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024524349"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt1352", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024932300", 
              "https://doi.org/10.1038/nbt1352"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.1618", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024956742", 
              "https://doi.org/10.1038/nbt.1618"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.276.5318.1558", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026996734"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jinsphys.2009.10.004", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027064062"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1101/gad.13.2.139", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027672773"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0092-8674(95)90082-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027894939"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1365-2583.2006.00656.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029197400"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.0510737103", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029264411"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1462-5822.2004.00399.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029359043"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1023/a:1005715805000", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030365779", 
              "https://doi.org/10.1023/a:1005715805000"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.241276898", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030499083"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0002-8223(95)00307-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030758850"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0002-8223(95)00307-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030758850"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0092-8674(04)00045-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031254572"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1006/dbio.2001.0563", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031500525"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1365-313x.1993.tb00177.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032255182"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0092-8674(02)00908-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032329761"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.febslet.2005.09.073", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032650684"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.febslet.2005.09.073", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032650684"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1365-2583.2010.01038.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032990653"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1242/dev.005629", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034172747"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.cell.2005.08.044", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034393359"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.95.23.13959", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034675476"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jinsphys.2008.04.019", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034959000"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/88150", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035031775", 
              "https://doi.org/10.1038/88150"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/88150", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035031775", 
              "https://doi.org/10.1038/88150"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1038/sj.emboj.7600385", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035197644"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1038/sj.emboj.7600488", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036230339"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0378-1119(00)00579-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037171219"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.peptides.2010.11.008", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037453304"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/39215", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037604014", 
              "https://doi.org/10.1038/39215"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/39215", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037604014", 
              "https://doi.org/10.1038/39215"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1101/gad.1370605", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037794461"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/emboj/cdf582", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038040167"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt966", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038342275", 
              "https://doi.org/10.1038/nbt966"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt966", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038342275", 
              "https://doi.org/10.1038/nbt966"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1046/j.1364-3703.2000.00038.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038911620"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature03462", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039130147", 
              "https://doi.org/10.1038/nature03462"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature03462", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039130147", 
              "https://doi.org/10.1038/nature03462"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1673/031.008.3001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039421981"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1038/oby.2006.82", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039535278"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1104/pp.001933", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039755302"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1105/tpc.5.12.1749", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039783008"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.0604698103", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040654936"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/385781a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044522927", 
              "https://doi.org/10.1038/385781a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.c200523200", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044612015"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.tibtech.2009.08.005", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044797628"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jinsphys.2008.12.005", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045019974"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.0611282104", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045090842"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.cell.2005.04.024", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045308565"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.cell.2005.04.024", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045308565"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s11306-007-0073-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045796393", 
              "https://doi.org/10.1007/s11306-007-0073-3"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2503/jjshs.60.409", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046656989"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1105/tpc.107.055517", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046729411"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1105/tpc.011452", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046916637"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt1359", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047100289", 
              "https://doi.org/10.1038/nbt1359"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrg2179", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047493400", 
              "https://doi.org/10.1038/nrg2179"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.cell.2004.06.017", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047794235"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1046/j.1365-313x.2001.01105.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047855591"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0168-9525(98)01510-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048320773"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1365-2583.2010.01049.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048636642"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature02873", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049891178", 
              "https://doi.org/10.1038/nature02873"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature02873", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049891178", 
              "https://doi.org/10.1038/nature02873"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature02519", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050357990", 
              "https://doi.org/10.1038/nature02519"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature02519", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050357990", 
              "https://doi.org/10.1038/nature02519"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1046/j.1365-313x.2001.01125.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050821868"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0305-0491(95)02037-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051365752"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt1382", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051437891", 
              "https://doi.org/10.1038/nbt1382"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jinsphys.2010.11.006", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051469627"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0092-8674(03)00801-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052068963"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1101/gad.1064703", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052230676"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/347737a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052448203", 
              "https://doi.org/10.1038/347737a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/35005107", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053082190", 
              "https://doi.org/10.1038/35005107"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/35005107", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053082190", 
              "https://doi.org/10.1038/35005107"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1099/vir.0.79944-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060400361"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.1068836", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1062445853"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.1073827", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1062446723"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.1102514", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1062450977"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/annotation/e8ca8d86-aa97-4951-8359-f8943c1dd935", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1065269703"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.14411/eje.2008.108", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1067295185"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/jn/130.8.2006", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1074676345"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1076570281", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1076809111", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1077163368", 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2013-03", 
        "datePublishedReg": "2013-03-01", 
        "description": "This review highlights the advances in the knowledge of RNA interference (RNAi) and discusses recent progress on the functionality of different components RNAi machinery operating in the organisms. The silencing of genes by RNA interference has become the technology of choice for investigation of gene functions in different organisms. The refinement in the knowledge of the endogenous RNAi pathways in plants along with the development of new strategies and applications for the improvement of nutritional value of important agricultural crops through suppression of genes in different plants have opened new vistas for nutritional security. The improvement in the nutritional status of the plants and reduction in the level of toxins or antinutrients was desired for long, but the available technology was not completely successful in achieving the tissue specific regulation of some genes. In the recent years, a number of economically important crop plants have been tested successfully for improving plant nutritional value through metabolic engineering using RNAi. The implications of this technology for crop improvement programs, including nutritional enrichment, reduction of antinutrients, disease, and insect control have been successfully tested in variety of crops with commercial considerations. The enhancement of the nutraceutical traits for the desired health benefits in common crop plants through manipulation of gene expression has been elaborated in this article. The tremendous potential with RNAi technology is expected to revolutionize the modern agriculture for meeting the growing challenges is discussed.", 
        "genre": "research_article", 
        "id": "sg:pub.10.1007/s12010-012-0046-5", 
        "inLanguage": [
          "en"
        ], 
        "isAccessibleForFree": false, 
        "isPartOf": [
          {
            "id": "sg:journal.1086169", 
            "issn": [
              "0273-2289", 
              "1559-0291"
            ], 
            "name": "Applied Biochemistry and Biotechnology", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "5", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "169"
          }
        ], 
        "name": "Advances in RNA Interference Technology and Its Impact on Nutritional Improvement, Disease and Insect Control in Plants", 
        "pagination": "1579-1605", 
        "productId": [
          {
            "name": "readcube_id", 
            "type": "PropertyValue", 
            "value": [
              "9410076754736b7ee3d79a1edcbfcc0544060fe39d502f2b4a03bfa65448112c"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "23322250"
            ]
          }, 
          {
            "name": "nlm_unique_id", 
            "type": "PropertyValue", 
            "value": [
              "8208561"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1007/s12010-012-0046-5"
            ]
          }, 
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1031079976"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1007/s12010-012-0046-5", 
          "https://app.dimensions.ai/details/publication/pub.1031079976"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2019-04-11T02:08", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8700_00000522.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "http://link.springer.com/10.1007%2Fs12010-012-0046-5"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s12010-012-0046-5'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s12010-012-0046-5'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s12010-012-0046-5'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s12010-012-0046-5'


     

    This table displays all metadata directly associated to this object as RDF triples.

    530 TRIPLES      21 PREDICATES      166 URIs      30 LITERALS      18 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1007/s12010-012-0046-5 schema:about N13f18ac0b8304df3af720fe1d6b605f2
    2 N1b639b09ec7849e0bf9e7688e756d4cf
    3 N43477119d4a049c6a53b10164e281544
    4 N48c157961fd34d0b856f3fab35eb8d9b
    5 N7a835987819641dabf4fce0fcdc87496
    6 N87dcbdb073b94a8caf6275176596c8ff
    7 N97cdc1901fa24e2d990c6eae694f9001
    8 Na7aaa3e596a043a094c502f0026bfbaa
    9 Nb63a778d986b41afbd1ebcc5383da3dc
    10 anzsrc-for:06
    11 anzsrc-for:0604
    12 schema:author Nbe484c6e2f40461bb1b8dddb753645bd
    13 schema:citation sg:pub.10.1007/bf00037068
    14 sg:pub.10.1007/s00299-004-0887-7
    15 sg:pub.10.1007/s00299-006-0277-4
    16 sg:pub.10.1007/s00425-003-1117-1
    17 sg:pub.10.1007/s11103-004-0393-x
    18 sg:pub.10.1007/s11306-007-0073-3
    19 sg:pub.10.1023/a:1005715805000
    20 sg:pub.10.1023/a:1024945920331
    21 sg:pub.10.1038/27579
    22 sg:pub.10.1038/347737a0
    23 sg:pub.10.1038/35005107
    24 sg:pub.10.1038/35036500
    25 sg:pub.10.1038/35888
    26 sg:pub.10.1038/385781a0
    27 sg:pub.10.1038/39215
    28 sg:pub.10.1038/88150
    29 sg:pub.10.1038/nature01957
    30 sg:pub.10.1038/nature02123
    31 sg:pub.10.1038/nature02519
    32 sg:pub.10.1038/nature02873
    33 sg:pub.10.1038/nature03462
    34 sg:pub.10.1038/nature07755
    35 sg:pub.10.1038/nbt.1618
    36 sg:pub.10.1038/nbt0203-131b
    37 sg:pub.10.1038/nbt1108
    38 sg:pub.10.1038/nbt1352
    39 sg:pub.10.1038/nbt1359
    40 sg:pub.10.1038/nbt1382
    41 sg:pub.10.1038/nbt966
    42 sg:pub.10.1038/nrg2179
    43 sg:pub.10.1038/nsmb777
    44 sg:pub.10.1186/1472-6750-3-1
    45 sg:pub.10.1186/1472-6750-3-3
    46 https://app.dimensions.ai/details/publication/pub.1076570281
    47 https://app.dimensions.ai/details/publication/pub.1076809111
    48 https://app.dimensions.ai/details/publication/pub.1077163368
    49 https://doi.org/10.1006/dbio.2001.0563
    50 https://doi.org/10.1006/jmbi.1993.1084
    51 https://doi.org/10.1016/0092-8674(95)90082-9
    52 https://doi.org/10.1016/0305-0491(95)02037-3
    53 https://doi.org/10.1016/j.cell.2004.06.017
    54 https://doi.org/10.1016/j.cell.2004.12.035
    55 https://doi.org/10.1016/j.cell.2005.04.024
    56 https://doi.org/10.1016/j.cell.2005.06.023
    57 https://doi.org/10.1016/j.cell.2005.08.044
    58 https://doi.org/10.1016/j.cub.2004.03.008
    59 https://doi.org/10.1016/j.febslet.2005.09.073
    60 https://doi.org/10.1016/j.ibmb.2008.10.011
    61 https://doi.org/10.1016/j.jinsphys.2008.04.019
    62 https://doi.org/10.1016/j.jinsphys.2008.12.005
    63 https://doi.org/10.1016/j.jinsphys.2009.10.004
    64 https://doi.org/10.1016/j.jinsphys.2010.11.006
    65 https://doi.org/10.1016/j.molbiopara.2006.03.013
    66 https://doi.org/10.1016/j.peptides.2010.11.008
    67 https://doi.org/10.1016/j.sbi.2006.12.002
    68 https://doi.org/10.1016/j.tibtech.2008.04.004
    69 https://doi.org/10.1016/j.tibtech.2009.08.005
    70 https://doi.org/10.1016/j.tplants.2008.05.004
    71 https://doi.org/10.1016/s0002-8223(95)00307-x
    72 https://doi.org/10.1016/s0092-8674(01)00547-5
    73 https://doi.org/10.1016/s0092-8674(01)00576-1
    74 https://doi.org/10.1016/s0092-8674(02)00908-x
    75 https://doi.org/10.1016/s0092-8674(03)00801-8
    76 https://doi.org/10.1016/s0092-8674(04)00045-5
    77 https://doi.org/10.1016/s0092-8674(04)00258-2
    78 https://doi.org/10.1016/s0168-1702(02)00353-2
    79 https://doi.org/10.1016/s0168-9525(98)01510-8
    80 https://doi.org/10.1016/s0378-1119(00)00579-5
    81 https://doi.org/10.1016/s0958-1669(00)00192-0
    82 https://doi.org/10.1016/s1360-1385(01)02055-6
    83 https://doi.org/10.1038/oby.2006.82
    84 https://doi.org/10.1038/sj.emboj.7600385
    85 https://doi.org/10.1038/sj.emboj.7600488
    86 https://doi.org/10.1046/j.1364-3703.2000.00038.x
    87 https://doi.org/10.1046/j.1365-313x.2001.01105.x
    88 https://doi.org/10.1046/j.1365-313x.2001.01125.x
    89 https://doi.org/10.1073/pnas.0509770102
    90 https://doi.org/10.1073/pnas.0510737103
    91 https://doi.org/10.1073/pnas.0604698103
    92 https://doi.org/10.1073/pnas.0605389103
    93 https://doi.org/10.1073/pnas.0611282104
    94 https://doi.org/10.1073/pnas.241276898
    95 https://doi.org/10.1073/pnas.95.23.13959
    96 https://doi.org/10.1074/jbc.c200523200
    97 https://doi.org/10.1080/00218839.2006.11101307
    98 https://doi.org/10.1093/emboj/20.23.6877
    99 https://doi.org/10.1093/emboj/cdf582
    100 https://doi.org/10.1093/jn/130.8.2006
    101 https://doi.org/10.1093/pcp/pch048
    102 https://doi.org/10.1098/rstb.2008.0168
    103 https://doi.org/10.1099/vir.0.79944-0
    104 https://doi.org/10.1101/gad.1026102
    105 https://doi.org/10.1101/gad.1064703
    106 https://doi.org/10.1101/gad.1184404
    107 https://doi.org/10.1101/gad.1187904
    108 https://doi.org/10.1101/gad.13.2.139
    109 https://doi.org/10.1101/gad.1370605
    110 https://doi.org/10.1101/gad.862301
    111 https://doi.org/10.1104/pp.001933
    112 https://doi.org/10.1104/pp.108.123273
    113 https://doi.org/10.1105/tpc.003061
    114 https://doi.org/10.1105/tpc.011452
    115 https://doi.org/10.1105/tpc.107.055517
    116 https://doi.org/10.1105/tpc.2.12.1201
    117 https://doi.org/10.1105/tpc.2.4.279
    118 https://doi.org/10.1105/tpc.2.4.291
    119 https://doi.org/10.1105/tpc.5.12.1749
    120 https://doi.org/10.1111/j.1365-2583.2006.00656.x
    121 https://doi.org/10.1111/j.1365-2583.2008.00839.x
    122 https://doi.org/10.1111/j.1365-2583.2010.01038.x
    123 https://doi.org/10.1111/j.1365-2583.2010.01049.x
    124 https://doi.org/10.1111/j.1365-2583.2010.01054.x
    125 https://doi.org/10.1111/j.1365-313x.1993.tb00177.x
    126 https://doi.org/10.1111/j.1365-313x.2005.02492.x
    127 https://doi.org/10.1111/j.1432-0436.2004.07202005.x
    128 https://doi.org/10.1111/j.1462-5822.2004.00399.x
    129 https://doi.org/10.1111/j.1467-7652.2005.00132.x
    130 https://doi.org/10.1111/j.1745-7270.2006.00124.x
    131 https://doi.org/10.1126/science.1068836
    132 https://doi.org/10.1126/science.1073827
    133 https://doi.org/10.1126/science.1102514
    134 https://doi.org/10.1126/science.1121638
    135 https://doi.org/10.1126/science.276.5318.1558
    136 https://doi.org/10.1242/dev.005629
    137 https://doi.org/10.1371/annotation/e8ca8d86-aa97-4951-8359-f8943c1dd935
    138 https://doi.org/10.14411/eje.2008.108
    139 https://doi.org/10.1673/031.008.3001
    140 https://doi.org/10.2503/jjshs.60.409
    141 schema:datePublished 2013-03
    142 schema:datePublishedReg 2013-03-01
    143 schema:description This review highlights the advances in the knowledge of RNA interference (RNAi) and discusses recent progress on the functionality of different components RNAi machinery operating in the organisms. The silencing of genes by RNA interference has become the technology of choice for investigation of gene functions in different organisms. The refinement in the knowledge of the endogenous RNAi pathways in plants along with the development of new strategies and applications for the improvement of nutritional value of important agricultural crops through suppression of genes in different plants have opened new vistas for nutritional security. The improvement in the nutritional status of the plants and reduction in the level of toxins or antinutrients was desired for long, but the available technology was not completely successful in achieving the tissue specific regulation of some genes. In the recent years, a number of economically important crop plants have been tested successfully for improving plant nutritional value through metabolic engineering using RNAi. The implications of this technology for crop improvement programs, including nutritional enrichment, reduction of antinutrients, disease, and insect control have been successfully tested in variety of crops with commercial considerations. The enhancement of the nutraceutical traits for the desired health benefits in common crop plants through manipulation of gene expression has been elaborated in this article. The tremendous potential with RNAi technology is expected to revolutionize the modern agriculture for meeting the growing challenges is discussed.
    144 schema:genre research_article
    145 schema:inLanguage en
    146 schema:isAccessibleForFree false
    147 schema:isPartOf N10157e68e9ca42f49048e2493227b1f2
    148 N505c90bfc89a407dbb0d4f8fdae746da
    149 sg:journal.1086169
    150 schema:name Advances in RNA Interference Technology and Its Impact on Nutritional Improvement, Disease and Insect Control in Plants
    151 schema:pagination 1579-1605
    152 schema:productId N0400cff5925a4db7acd62ff3e7cd8df3
    153 N6bce224cce4845e2a07c4751a4d542e3
    154 N82939a5ae8e04b8cafd74109bcd05a84
    155 Na5f6868473da4ff39651bcfad466c0b2
    156 Nb3bea098e6ac447882030aa16efa6ed1
    157 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031079976
    158 https://doi.org/10.1007/s12010-012-0046-5
    159 schema:sdDatePublished 2019-04-11T02:08
    160 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    161 schema:sdPublisher N13a9d8c8c5ce4ddb9430c16e3ebbec14
    162 schema:url http://link.springer.com/10.1007%2Fs12010-012-0046-5
    163 sgo:license sg:explorer/license/
    164 sgo:sdDataset articles
    165 rdf:type schema:ScholarlyArticle
    166 N0400cff5925a4db7acd62ff3e7cd8df3 schema:name readcube_id
    167 schema:value 9410076754736b7ee3d79a1edcbfcc0544060fe39d502f2b4a03bfa65448112c
    168 rdf:type schema:PropertyValue
    169 N10157e68e9ca42f49048e2493227b1f2 schema:issueNumber 5
    170 rdf:type schema:PublicationIssue
    171 N13a9d8c8c5ce4ddb9430c16e3ebbec14 schema:name Springer Nature - SN SciGraph project
    172 rdf:type schema:Organization
    173 N13f18ac0b8304df3af720fe1d6b605f2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    174 schema:name Nutritive Value
    175 rdf:type schema:DefinedTerm
    176 N1b639b09ec7849e0bf9e7688e756d4cf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    177 schema:name Crops, Agricultural
    178 rdf:type schema:DefinedTerm
    179 N43477119d4a049c6a53b10164e281544 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    180 schema:name Gene Expression Regulation, Plant
    181 rdf:type schema:DefinedTerm
    182 N48c157961fd34d0b856f3fab35eb8d9b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    183 schema:name Plants, Genetically Modified
    184 rdf:type schema:DefinedTerm
    185 N505c90bfc89a407dbb0d4f8fdae746da schema:volumeNumber 169
    186 rdf:type schema:PublicationVolume
    187 N6bce224cce4845e2a07c4751a4d542e3 schema:name dimensions_id
    188 schema:value pub.1031079976
    189 rdf:type schema:PropertyValue
    190 N7a835987819641dabf4fce0fcdc87496 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    191 schema:name RNA Interference
    192 rdf:type schema:DefinedTerm
    193 N82939a5ae8e04b8cafd74109bcd05a84 schema:name doi
    194 schema:value 10.1007/s12010-012-0046-5
    195 rdf:type schema:PropertyValue
    196 N8366efd62377438c9bc0df6abc831034 rdf:first sg:person.01337170554.58
    197 rdf:rest rdf:nil
    198 N87dcbdb073b94a8caf6275176596c8ff schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    199 schema:name Plants
    200 rdf:type schema:DefinedTerm
    201 N97cdc1901fa24e2d990c6eae694f9001 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    202 schema:name Metabolic Engineering
    203 rdf:type schema:DefinedTerm
    204 Na5f6868473da4ff39651bcfad466c0b2 schema:name nlm_unique_id
    205 schema:value 8208561
    206 rdf:type schema:PropertyValue
    207 Na7aaa3e596a043a094c502f0026bfbaa schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    208 schema:name Insect Control
    209 rdf:type schema:DefinedTerm
    210 Nb3bea098e6ac447882030aa16efa6ed1 schema:name pubmed_id
    211 schema:value 23322250
    212 rdf:type schema:PropertyValue
    213 Nb63a778d986b41afbd1ebcc5383da3dc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    214 schema:name Plant Proteins
    215 rdf:type schema:DefinedTerm
    216 Nbe484c6e2f40461bb1b8dddb753645bd rdf:first sg:person.010373015235.05
    217 rdf:rest N8366efd62377438c9bc0df6abc831034
    218 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
    219 schema:name Biological Sciences
    220 rdf:type schema:DefinedTerm
    221 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
    222 schema:name Genetics
    223 rdf:type schema:DefinedTerm
    224 sg:journal.1086169 schema:issn 0273-2289
    225 1559-0291
    226 schema:name Applied Biochemistry and Biotechnology
    227 rdf:type schema:Periodical
    228 sg:person.010373015235.05 schema:affiliation https://www.grid.ac/institutes/grid.169077.e
    229 schema:familyName Katoch
    230 schema:givenName Rajan
    231 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010373015235.05
    232 rdf:type schema:Person
    233 sg:person.01337170554.58 schema:affiliation https://www.grid.ac/institutes/grid.412577.2
    234 schema:familyName Thakur
    235 schema:givenName Neelam
    236 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01337170554.58
    237 rdf:type schema:Person
    238 sg:pub.10.1007/bf00037068 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008140582
    239 https://doi.org/10.1007/bf00037068
    240 rdf:type schema:CreativeWork
    241 sg:pub.10.1007/s00299-004-0887-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015503478
    242 https://doi.org/10.1007/s00299-004-0887-7
    243 rdf:type schema:CreativeWork
    244 sg:pub.10.1007/s00299-006-0277-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004233953
    245 https://doi.org/10.1007/s00299-006-0277-4
    246 rdf:type schema:CreativeWork
    247 sg:pub.10.1007/s00425-003-1117-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001560219
    248 https://doi.org/10.1007/s00425-003-1117-1
    249 rdf:type schema:CreativeWork
    250 sg:pub.10.1007/s11103-004-0393-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1008770391
    251 https://doi.org/10.1007/s11103-004-0393-x
    252 rdf:type schema:CreativeWork
    253 sg:pub.10.1007/s11306-007-0073-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045796393
    254 https://doi.org/10.1007/s11306-007-0073-3
    255 rdf:type schema:CreativeWork
    256 sg:pub.10.1023/a:1005715805000 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030365779
    257 https://doi.org/10.1023/a:1005715805000
    258 rdf:type schema:CreativeWork
    259 sg:pub.10.1023/a:1024945920331 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006645207
    260 https://doi.org/10.1023/a:1024945920331
    261 rdf:type schema:CreativeWork
    262 sg:pub.10.1038/27579 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023285321
    263 https://doi.org/10.1038/27579
    264 rdf:type schema:CreativeWork
    265 sg:pub.10.1038/347737a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052448203
    266 https://doi.org/10.1038/347737a0
    267 rdf:type schema:CreativeWork
    268 sg:pub.10.1038/35005107 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053082190
    269 https://doi.org/10.1038/35005107
    270 rdf:type schema:CreativeWork
    271 sg:pub.10.1038/35036500 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023274001
    272 https://doi.org/10.1038/35036500
    273 rdf:type schema:CreativeWork
    274 sg:pub.10.1038/35888 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018713804
    275 https://doi.org/10.1038/35888
    276 rdf:type schema:CreativeWork
    277 sg:pub.10.1038/385781a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044522927
    278 https://doi.org/10.1038/385781a0
    279 rdf:type schema:CreativeWork
    280 sg:pub.10.1038/39215 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037604014
    281 https://doi.org/10.1038/39215
    282 rdf:type schema:CreativeWork
    283 sg:pub.10.1038/88150 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035031775
    284 https://doi.org/10.1038/88150
    285 rdf:type schema:CreativeWork
    286 sg:pub.10.1038/nature01957 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007929702
    287 https://doi.org/10.1038/nature01957
    288 rdf:type schema:CreativeWork
    289 sg:pub.10.1038/nature02123 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022420805
    290 https://doi.org/10.1038/nature02123
    291 rdf:type schema:CreativeWork
    292 sg:pub.10.1038/nature02519 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050357990
    293 https://doi.org/10.1038/nature02519
    294 rdf:type schema:CreativeWork
    295 sg:pub.10.1038/nature02873 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049891178
    296 https://doi.org/10.1038/nature02873
    297 rdf:type schema:CreativeWork
    298 sg:pub.10.1038/nature03462 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039130147
    299 https://doi.org/10.1038/nature03462
    300 rdf:type schema:CreativeWork
    301 sg:pub.10.1038/nature07755 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022586447
    302 https://doi.org/10.1038/nature07755
    303 rdf:type schema:CreativeWork
    304 sg:pub.10.1038/nbt.1618 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024956742
    305 https://doi.org/10.1038/nbt.1618
    306 rdf:type schema:CreativeWork
    307 sg:pub.10.1038/nbt0203-131b schema:sameAs https://app.dimensions.ai/details/publication/pub.1001112654
    308 https://doi.org/10.1038/nbt0203-131b
    309 rdf:type schema:CreativeWork
    310 sg:pub.10.1038/nbt1108 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018379429
    311 https://doi.org/10.1038/nbt1108
    312 rdf:type schema:CreativeWork
    313 sg:pub.10.1038/nbt1352 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024932300
    314 https://doi.org/10.1038/nbt1352
    315 rdf:type schema:CreativeWork
    316 sg:pub.10.1038/nbt1359 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047100289
    317 https://doi.org/10.1038/nbt1359
    318 rdf:type schema:CreativeWork
    319 sg:pub.10.1038/nbt1382 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051437891
    320 https://doi.org/10.1038/nbt1382
    321 rdf:type schema:CreativeWork
    322 sg:pub.10.1038/nbt966 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038342275
    323 https://doi.org/10.1038/nbt966
    324 rdf:type schema:CreativeWork
    325 sg:pub.10.1038/nrg2179 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047493400
    326 https://doi.org/10.1038/nrg2179
    327 rdf:type schema:CreativeWork
    328 sg:pub.10.1038/nsmb777 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010191056
    329 https://doi.org/10.1038/nsmb777
    330 rdf:type schema:CreativeWork
    331 sg:pub.10.1186/1472-6750-3-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018235747
    332 https://doi.org/10.1186/1472-6750-3-1
    333 rdf:type schema:CreativeWork
    334 sg:pub.10.1186/1472-6750-3-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021968571
    335 https://doi.org/10.1186/1472-6750-3-3
    336 rdf:type schema:CreativeWork
    337 https://app.dimensions.ai/details/publication/pub.1076570281 schema:CreativeWork
    338 https://app.dimensions.ai/details/publication/pub.1076809111 schema:CreativeWork
    339 https://app.dimensions.ai/details/publication/pub.1077163368 schema:CreativeWork
    340 https://doi.org/10.1006/dbio.2001.0563 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031500525
    341 rdf:type schema:CreativeWork
    342 https://doi.org/10.1006/jmbi.1993.1084 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007778756
    343 rdf:type schema:CreativeWork
    344 https://doi.org/10.1016/0092-8674(95)90082-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027894939
    345 rdf:type schema:CreativeWork
    346 https://doi.org/10.1016/0305-0491(95)02037-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051365752
    347 rdf:type schema:CreativeWork
    348 https://doi.org/10.1016/j.cell.2004.06.017 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047794235
    349 rdf:type schema:CreativeWork
    350 https://doi.org/10.1016/j.cell.2004.12.035 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020132624
    351 rdf:type schema:CreativeWork
    352 https://doi.org/10.1016/j.cell.2005.04.024 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045308565
    353 rdf:type schema:CreativeWork
    354 https://doi.org/10.1016/j.cell.2005.06.023 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009711015
    355 rdf:type schema:CreativeWork
    356 https://doi.org/10.1016/j.cell.2005.08.044 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034393359
    357 rdf:type schema:CreativeWork
    358 https://doi.org/10.1016/j.cub.2004.03.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024046661
    359 rdf:type schema:CreativeWork
    360 https://doi.org/10.1016/j.febslet.2005.09.073 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032650684
    361 rdf:type schema:CreativeWork
    362 https://doi.org/10.1016/j.ibmb.2008.10.011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007660317
    363 rdf:type schema:CreativeWork
    364 https://doi.org/10.1016/j.jinsphys.2008.04.019 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034959000
    365 rdf:type schema:CreativeWork
    366 https://doi.org/10.1016/j.jinsphys.2008.12.005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045019974
    367 rdf:type schema:CreativeWork
    368 https://doi.org/10.1016/j.jinsphys.2009.10.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027064062
    369 rdf:type schema:CreativeWork
    370 https://doi.org/10.1016/j.jinsphys.2010.11.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051469627
    371 rdf:type schema:CreativeWork
    372 https://doi.org/10.1016/j.molbiopara.2006.03.013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024524349
    373 rdf:type schema:CreativeWork
    374 https://doi.org/10.1016/j.peptides.2010.11.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037453304
    375 rdf:type schema:CreativeWork
    376 https://doi.org/10.1016/j.sbi.2006.12.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012392121
    377 rdf:type schema:CreativeWork
    378 https://doi.org/10.1016/j.tibtech.2008.04.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015574559
    379 rdf:type schema:CreativeWork
    380 https://doi.org/10.1016/j.tibtech.2009.08.005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044797628
    381 rdf:type schema:CreativeWork
    382 https://doi.org/10.1016/j.tplants.2008.05.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008424940
    383 rdf:type schema:CreativeWork
    384 https://doi.org/10.1016/s0002-8223(95)00307-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1030758850
    385 rdf:type schema:CreativeWork
    386 https://doi.org/10.1016/s0092-8674(01)00547-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021383396
    387 rdf:type schema:CreativeWork
    388 https://doi.org/10.1016/s0092-8674(01)00576-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019924014
    389 rdf:type schema:CreativeWork
    390 https://doi.org/10.1016/s0092-8674(02)00908-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1032329761
    391 rdf:type schema:CreativeWork
    392 https://doi.org/10.1016/s0092-8674(03)00801-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052068963
    393 rdf:type schema:CreativeWork
    394 https://doi.org/10.1016/s0092-8674(04)00045-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031254572
    395 rdf:type schema:CreativeWork
    396 https://doi.org/10.1016/s0092-8674(04)00258-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014311702
    397 rdf:type schema:CreativeWork
    398 https://doi.org/10.1016/s0168-1702(02)00353-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004127356
    399 rdf:type schema:CreativeWork
    400 https://doi.org/10.1016/s0168-9525(98)01510-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048320773
    401 rdf:type schema:CreativeWork
    402 https://doi.org/10.1016/s0378-1119(00)00579-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037171219
    403 rdf:type schema:CreativeWork
    404 https://doi.org/10.1016/s0958-1669(00)00192-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005602147
    405 rdf:type schema:CreativeWork
    406 https://doi.org/10.1016/s1360-1385(01)02055-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008001256
    407 rdf:type schema:CreativeWork
    408 https://doi.org/10.1038/oby.2006.82 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039535278
    409 rdf:type schema:CreativeWork
    410 https://doi.org/10.1038/sj.emboj.7600385 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035197644
    411 rdf:type schema:CreativeWork
    412 https://doi.org/10.1038/sj.emboj.7600488 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036230339
    413 rdf:type schema:CreativeWork
    414 https://doi.org/10.1046/j.1364-3703.2000.00038.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1038911620
    415 rdf:type schema:CreativeWork
    416 https://doi.org/10.1046/j.1365-313x.2001.01105.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1047855591
    417 rdf:type schema:CreativeWork
    418 https://doi.org/10.1046/j.1365-313x.2001.01125.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1050821868
    419 rdf:type schema:CreativeWork
    420 https://doi.org/10.1073/pnas.0509770102 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006641044
    421 rdf:type schema:CreativeWork
    422 https://doi.org/10.1073/pnas.0510737103 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029264411
    423 rdf:type schema:CreativeWork
    424 https://doi.org/10.1073/pnas.0604698103 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040654936
    425 rdf:type schema:CreativeWork
    426 https://doi.org/10.1073/pnas.0605389103 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011149301
    427 rdf:type schema:CreativeWork
    428 https://doi.org/10.1073/pnas.0611282104 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045090842
    429 rdf:type schema:CreativeWork
    430 https://doi.org/10.1073/pnas.241276898 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030499083
    431 rdf:type schema:CreativeWork
    432 https://doi.org/10.1073/pnas.95.23.13959 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034675476
    433 rdf:type schema:CreativeWork
    434 https://doi.org/10.1074/jbc.c200523200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044612015
    435 rdf:type schema:CreativeWork
    436 https://doi.org/10.1080/00218839.2006.11101307 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010004387
    437 rdf:type schema:CreativeWork
    438 https://doi.org/10.1093/emboj/20.23.6877 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004775429
    439 rdf:type schema:CreativeWork
    440 https://doi.org/10.1093/emboj/cdf582 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038040167
    441 rdf:type schema:CreativeWork
    442 https://doi.org/10.1093/jn/130.8.2006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1074676345
    443 rdf:type schema:CreativeWork
    444 https://doi.org/10.1093/pcp/pch048 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009291521
    445 rdf:type schema:CreativeWork
    446 https://doi.org/10.1098/rstb.2008.0168 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006247079
    447 rdf:type schema:CreativeWork
    448 https://doi.org/10.1099/vir.0.79944-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060400361
    449 rdf:type schema:CreativeWork
    450 https://doi.org/10.1101/gad.1026102 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014003859
    451 rdf:type schema:CreativeWork
    452 https://doi.org/10.1101/gad.1064703 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052230676
    453 rdf:type schema:CreativeWork
    454 https://doi.org/10.1101/gad.1184404 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024436325
    455 rdf:type schema:CreativeWork
    456 https://doi.org/10.1101/gad.1187904 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015033164
    457 rdf:type schema:CreativeWork
    458 https://doi.org/10.1101/gad.13.2.139 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027672773
    459 rdf:type schema:CreativeWork
    460 https://doi.org/10.1101/gad.1370605 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037794461
    461 rdf:type schema:CreativeWork
    462 https://doi.org/10.1101/gad.862301 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000961502
    463 rdf:type schema:CreativeWork
    464 https://doi.org/10.1104/pp.001933 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039755302
    465 rdf:type schema:CreativeWork
    466 https://doi.org/10.1104/pp.108.123273 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015037401
    467 rdf:type schema:CreativeWork
    468 https://doi.org/10.1105/tpc.003061 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016138027
    469 rdf:type schema:CreativeWork
    470 https://doi.org/10.1105/tpc.011452 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046916637
    471 rdf:type schema:CreativeWork
    472 https://doi.org/10.1105/tpc.107.055517 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046729411
    473 rdf:type schema:CreativeWork
    474 https://doi.org/10.1105/tpc.2.12.1201 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013352558
    475 rdf:type schema:CreativeWork
    476 https://doi.org/10.1105/tpc.2.4.279 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014921424
    477 rdf:type schema:CreativeWork
    478 https://doi.org/10.1105/tpc.2.4.291 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017136927
    479 rdf:type schema:CreativeWork
    480 https://doi.org/10.1105/tpc.5.12.1749 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039783008
    481 rdf:type schema:CreativeWork
    482 https://doi.org/10.1111/j.1365-2583.2006.00656.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1029197400
    483 rdf:type schema:CreativeWork
    484 https://doi.org/10.1111/j.1365-2583.2008.00839.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1024029729
    485 rdf:type schema:CreativeWork
    486 https://doi.org/10.1111/j.1365-2583.2010.01038.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1032990653
    487 rdf:type schema:CreativeWork
    488 https://doi.org/10.1111/j.1365-2583.2010.01049.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1048636642
    489 rdf:type schema:CreativeWork
    490 https://doi.org/10.1111/j.1365-2583.2010.01054.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1006858786
    491 rdf:type schema:CreativeWork
    492 https://doi.org/10.1111/j.1365-313x.1993.tb00177.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1032255182
    493 rdf:type schema:CreativeWork
    494 https://doi.org/10.1111/j.1365-313x.2005.02492.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1016891838
    495 rdf:type schema:CreativeWork
    496 https://doi.org/10.1111/j.1432-0436.2004.07202005.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1009278115
    497 rdf:type schema:CreativeWork
    498 https://doi.org/10.1111/j.1462-5822.2004.00399.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1029359043
    499 rdf:type schema:CreativeWork
    500 https://doi.org/10.1111/j.1467-7652.2005.00132.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1020593219
    501 rdf:type schema:CreativeWork
    502 https://doi.org/10.1111/j.1745-7270.2006.00124.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1004108342
    503 rdf:type schema:CreativeWork
    504 https://doi.org/10.1126/science.1068836 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062445853
    505 rdf:type schema:CreativeWork
    506 https://doi.org/10.1126/science.1073827 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062446723
    507 rdf:type schema:CreativeWork
    508 https://doi.org/10.1126/science.1102514 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062450977
    509 rdf:type schema:CreativeWork
    510 https://doi.org/10.1126/science.1121638 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016990355
    511 rdf:type schema:CreativeWork
    512 https://doi.org/10.1126/science.276.5318.1558 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026996734
    513 rdf:type schema:CreativeWork
    514 https://doi.org/10.1242/dev.005629 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034172747
    515 rdf:type schema:CreativeWork
    516 https://doi.org/10.1371/annotation/e8ca8d86-aa97-4951-8359-f8943c1dd935 schema:sameAs https://app.dimensions.ai/details/publication/pub.1065269703
    517 rdf:type schema:CreativeWork
    518 https://doi.org/10.14411/eje.2008.108 schema:sameAs https://app.dimensions.ai/details/publication/pub.1067295185
    519 rdf:type schema:CreativeWork
    520 https://doi.org/10.1673/031.008.3001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039421981
    521 rdf:type schema:CreativeWork
    522 https://doi.org/10.2503/jjshs.60.409 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046656989
    523 rdf:type schema:CreativeWork
    524 https://www.grid.ac/institutes/grid.169077.e schema:alternateName Purdue University
    525 schema:name Biochemistry Laboratory, Department of Crop Improvement, College of Agriculture, CSK Himachal Pradesh Krishi Vishvavidyalaya, 176062, Palampur, India
    526 Department of Entomology, Purdue University, 47907, West Lafayette, IN, USA
    527 rdf:type schema:Organization
    528 https://www.grid.ac/institutes/grid.412577.2 schema:alternateName Punjab Agricultural University
    529 schema:name Department of Biosciences, Punjab Agricultural University, 141004, Ludhiana, India
    530 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...