Staged Revision for Knee Arthroplasty Infection: What Is the Role of Serologic Tests Before Reimplantation? View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2009-07

AUTHORS

Elie Ghanem, Khalid Azzam, Mark Seeley, Ashish Joshi, Javad Parvizi

ABSTRACT

Erythrocyte sedimentation rate and C-reactive protein are common preoperative diagnostic markers for prosthetic joint infection but their prognostic role before reimplantation has yet to be defined. We therefore determined the prognostic value of erythrocyte sedimentation rate and C-reactive protein performed before second-stage reimplantation for the treatment of infected total knee arthroplasty (TKA). We studied 109 patients who had undergone two-stage revision TKA for sepsis from 1999 to 2006. Receiver operating characteristic curves were constructed to determine the discriminatory value of erythrocyte sedimentation rate and C-reactive protein before reimplantation in predicting persistent infection. Twenty-three of the 109 patients (21%) required revision surgery for recurrence of prosthetic joint infection. The receiver operating characteristic areas under the curve suggested erythrocyte sedimentation rate and C-reactive protein poorly predicted persistent infection after TKA reimplantation. Cutoff values could not be obtained because of the high variance. We reached similar conclusions regarding the change in erythrocyte sedimentation rate and C-reactive protein levels from time of resection. More accurate diagnostic tools are needed to support clinical judgment in monitoring infection progress and thus deciding whether to proceed with TKA reimplantation. LEVEL OF EVIDENCE: Level II, therapeutic study. More... »

PAGES

1699-1705

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11999-009-0742-9

DOI

http://dx.doi.org/10.1007/s11999-009-0742-9

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1020427925

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/19241115


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Arthroplasty, Replacement, Knee", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Biomarkers", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Blood Sedimentation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "C-Reactive Protein", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Follow-Up Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Predictive Value of Tests", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Prognosis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Prosthesis-Related Infections", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "ROC Curve", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Recurrence", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Reoperation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Retrospective Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sensitivity and Specificity", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Thomas Jefferson University", 
          "id": "https://www.grid.ac/institutes/grid.265008.9", 
          "name": [
            "Rothman Institute of Orthopedics at Jefferson, Thomas Jefferson University, 925 Chestnut Street, 19107, Philadelphia, PA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ghanem", 
        "givenName": "Elie", 
        "id": "sg:person.01311370364.52", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01311370364.52"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Thomas Jefferson University", 
          "id": "https://www.grid.ac/institutes/grid.265008.9", 
          "name": [
            "Rothman Institute of Orthopedics at Jefferson, Thomas Jefferson University, 925 Chestnut Street, 19107, Philadelphia, PA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Azzam", 
        "givenName": "Khalid", 
        "id": "sg:person.0766260352.99", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0766260352.99"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Thomas Jefferson University", 
          "id": "https://www.grid.ac/institutes/grid.265008.9", 
          "name": [
            "Rothman Institute of Orthopedics at Jefferson, Thomas Jefferson University, 925 Chestnut Street, 19107, Philadelphia, PA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Seeley", 
        "givenName": "Mark", 
        "id": "sg:person.01113557312.13", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01113557312.13"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Thomas Jefferson University", 
          "id": "https://www.grid.ac/institutes/grid.265008.9", 
          "name": [
            "Rothman Institute of Orthopedics at Jefferson, Thomas Jefferson University, 925 Chestnut Street, 19107, Philadelphia, PA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Joshi", 
        "givenName": "Ashish", 
        "id": "sg:person.0707232342.18", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0707232342.18"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Thomas Jefferson University", 
          "id": "https://www.grid.ac/institutes/grid.265008.9", 
          "name": [
            "Rothman Institute of Orthopedics at Jefferson, Thomas Jefferson University, 925 Chestnut Street, 19107, Philadelphia, PA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Parvizi", 
        "givenName": "Javad", 
        "id": "sg:person.01357752371.70", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01357752371.70"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1056/nejmoa061588", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005008919"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0736-4679(97)00197-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010999213"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1302/0301-620x.86b5.14887", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017256548"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.blo.0000147713.64235.73", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017486238"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.blo.0000147713.64235.73", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017486238"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.blo.0000147713.64235.73", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017486238"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1302/0301-620x.89b1.17485", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021659852"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm198701293160509", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023363589"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0883-5403(98)90071-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024769941"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/374554", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025185899"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1385/ir:30:3:261", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029591810", 
          "https://doi.org/10.1385/ir:30:3:261"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.blo.0000218727.14097.d5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041765029"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.blo.0000218727.14097.d5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041765029"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.amjmed.2004.06.022", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043739815"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.arth.2006.01.028", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048540176"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00003086-198404000-00015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060160620"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00003086-198404000-00015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060160620"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00003086-198404000-00015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060160620"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00003086-198404000-00015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060160620"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00003086-199610000-00016", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060166566"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00003086-199610000-00016", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060166566"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00003086-199610000-00016", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060166566"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00003086-199610000-00016", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060166566"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00003086-199712000-00003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060167117"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00003086-199712000-00003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060167117"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00003086-199712000-00003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060167117"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2106/00004623-198365080-00008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068888305"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2106/00004623-199604000-00005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068892334"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2106/00004623-200011000-00006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068894068"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2106/00004623-200707000-00001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068897883"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2106/jbjs.d.02602", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068899467"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2106/jbjs.d.02602", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068899467"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2106/jbjs.d.02602", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068899467"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2106/jbjs.f.00609", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068900155"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2106/jbjs.f.00609", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068900155"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2106/jbjs.f.00609", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068900155"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074808514", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077510585", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/blo.0b013e318157eb1e", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1077510585"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/blo.0b013e318157eb1e", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1077510585"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/blo.0b013e318157eb1e", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1077510585"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0272-2712(18)30408-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1082752492"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1302/0301-620x.78b3.0780431", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1082888034"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2009-07", 
    "datePublishedReg": "2009-07-01", 
    "description": "Erythrocyte sedimentation rate and C-reactive protein are common preoperative diagnostic markers for prosthetic joint infection but their prognostic role before reimplantation has yet to be defined. We therefore determined the prognostic value of erythrocyte sedimentation rate and C-reactive protein performed before second-stage reimplantation for the treatment of infected total knee arthroplasty (TKA). We studied 109 patients who had undergone two-stage revision TKA for sepsis from 1999 to 2006. Receiver operating characteristic curves were constructed to determine the discriminatory value of erythrocyte sedimentation rate and C-reactive protein before reimplantation in predicting persistent infection. Twenty-three of the 109 patients (21%) required revision surgery for recurrence of prosthetic joint infection. The receiver operating characteristic areas under the curve suggested erythrocyte sedimentation rate and C-reactive protein poorly predicted persistent infection after TKA reimplantation. Cutoff values could not be obtained because of the high variance. We reached similar conclusions regarding the change in erythrocyte sedimentation rate and C-reactive protein levels from time of resection. More accurate diagnostic tools are needed to support clinical judgment in monitoring infection progress and thus deciding whether to proceed with TKA reimplantation.\nLEVEL OF EVIDENCE: Level II, therapeutic study.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s11999-009-0742-9", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1007212", 
        "issn": [
          "0009-921X", 
          "1528-1132"
        ], 
        "name": "Clinical Orthopaedics and Related Research\u00ae", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "7", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "467"
      }
    ], 
    "name": "Staged Revision for Knee Arthroplasty Infection: What Is the Role of Serologic Tests Before Reimplantation?", 
    "pagination": "1699-1705", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "6155976ac654ad8ff5c0b6242d7bc2a3f7f1adb560187a7a7211371178d83d58"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "19241115"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "0075674"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s11999-009-0742-9"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1020427925"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s11999-009-0742-9", 
      "https://app.dimensions.ai/details/publication/pub.1020427925"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T14:12", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8660_00000521.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007%2Fs11999-009-0742-9"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s11999-009-0742-9'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s11999-009-0742-9'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s11999-009-0742-9'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s11999-009-0742-9'


 

This table displays all metadata directly associated to this object as RDF triples.

242 TRIPLES      21 PREDICATES      72 URIs      38 LITERALS      26 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s11999-009-0742-9 schema:about N0d050e53e5a64a038d6bb10c0685260f
2 N1ba6c17dfea7462291877828f36ba029
3 N2366bb91843a423c8aa4f1b4e3546d21
4 N4fcb2f00c49c4ccca2195d68ccdcced4
5 N5279b5ca67ee4ec0bd105ad219d55967
6 N616140f5bea946e58b19629d2bf68256
7 N6c737c524ff54e7bbc51f6f92a0f5be9
8 N7ba9cbd23ae84ccb97e0c3e263f8caa7
9 Naa8d53ea48b54d68ae90ac774781cfdf
10 Nb5a7700467d949b1be7182711923ab94
11 Nc35be40154164e099d47bf4dcbc71e91
12 Ncba249d9173348d2a62a7a030b407b97
13 Nd0a87ca885fa4fa3a0fcbf2b50cb510a
14 Nd17cb4bede2843f3b29a35a13410a050
15 Ne343db3010b94d47bd10df046cf9b295
16 Ne769c92fd72241f9bdc33ade976f5cbf
17 Nea5ec6a3c0ef41458f416a7105f09544
18 anzsrc-for:11
19 anzsrc-for:1103
20 schema:author Nef7dbc617d764b89af17f3d42d4695de
21 schema:citation sg:pub.10.1385/ir:30:3:261
22 https://app.dimensions.ai/details/publication/pub.1074808514
23 https://app.dimensions.ai/details/publication/pub.1077510585
24 https://doi.org/10.1016/j.amjmed.2004.06.022
25 https://doi.org/10.1016/j.arth.2006.01.028
26 https://doi.org/10.1016/s0272-2712(18)30408-6
27 https://doi.org/10.1016/s0736-4679(97)00197-2
28 https://doi.org/10.1016/s0883-5403(98)90071-7
29 https://doi.org/10.1056/nejm198701293160509
30 https://doi.org/10.1056/nejmoa061588
31 https://doi.org/10.1086/374554
32 https://doi.org/10.1097/00003086-198404000-00015
33 https://doi.org/10.1097/00003086-199610000-00016
34 https://doi.org/10.1097/00003086-199712000-00003
35 https://doi.org/10.1097/01.blo.0000147713.64235.73
36 https://doi.org/10.1097/01.blo.0000218727.14097.d5
37 https://doi.org/10.1097/blo.0b013e318157eb1e
38 https://doi.org/10.1302/0301-620x.78b3.0780431
39 https://doi.org/10.1302/0301-620x.86b5.14887
40 https://doi.org/10.1302/0301-620x.89b1.17485
41 https://doi.org/10.2106/00004623-198365080-00008
42 https://doi.org/10.2106/00004623-199604000-00005
43 https://doi.org/10.2106/00004623-200011000-00006
44 https://doi.org/10.2106/00004623-200707000-00001
45 https://doi.org/10.2106/jbjs.d.02602
46 https://doi.org/10.2106/jbjs.f.00609
47 schema:datePublished 2009-07
48 schema:datePublishedReg 2009-07-01
49 schema:description Erythrocyte sedimentation rate and C-reactive protein are common preoperative diagnostic markers for prosthetic joint infection but their prognostic role before reimplantation has yet to be defined. We therefore determined the prognostic value of erythrocyte sedimentation rate and C-reactive protein performed before second-stage reimplantation for the treatment of infected total knee arthroplasty (TKA). We studied 109 patients who had undergone two-stage revision TKA for sepsis from 1999 to 2006. Receiver operating characteristic curves were constructed to determine the discriminatory value of erythrocyte sedimentation rate and C-reactive protein before reimplantation in predicting persistent infection. Twenty-three of the 109 patients (21%) required revision surgery for recurrence of prosthetic joint infection. The receiver operating characteristic areas under the curve suggested erythrocyte sedimentation rate and C-reactive protein poorly predicted persistent infection after TKA reimplantation. Cutoff values could not be obtained because of the high variance. We reached similar conclusions regarding the change in erythrocyte sedimentation rate and C-reactive protein levels from time of resection. More accurate diagnostic tools are needed to support clinical judgment in monitoring infection progress and thus deciding whether to proceed with TKA reimplantation. LEVEL OF EVIDENCE: Level II, therapeutic study.
50 schema:genre research_article
51 schema:inLanguage en
52 schema:isAccessibleForFree true
53 schema:isPartOf N5e7fdef9fc5641fab183caa2b9b9a374
54 Ndb247c288b6741d193b545ec60828e57
55 sg:journal.1007212
56 schema:name Staged Revision for Knee Arthroplasty Infection: What Is the Role of Serologic Tests Before Reimplantation?
57 schema:pagination 1699-1705
58 schema:productId N4124ff009cc84198b40facfc4a9d12d2
59 Nd1a5e7d0de9a4742866e8910f884ef68
60 Nd2f900fe49384b5eaa0c12a8897b8dbc
61 Nd812146dbe164a9bab98406dc7366b94
62 Nda5e507043b24e1a81fe66cf64613921
63 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020427925
64 https://doi.org/10.1007/s11999-009-0742-9
65 schema:sdDatePublished 2019-04-10T14:12
66 schema:sdLicense https://scigraph.springernature.com/explorer/license/
67 schema:sdPublisher N5aebc503688b406baa8f0975807a422f
68 schema:url http://link.springer.com/10.1007%2Fs11999-009-0742-9
69 sgo:license sg:explorer/license/
70 sgo:sdDataset articles
71 rdf:type schema:ScholarlyArticle
72 N0d050e53e5a64a038d6bb10c0685260f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
73 schema:name Blood Sedimentation
74 rdf:type schema:DefinedTerm
75 N1ba6c17dfea7462291877828f36ba029 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
76 schema:name Aged
77 rdf:type schema:DefinedTerm
78 N2366bb91843a423c8aa4f1b4e3546d21 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
79 schema:name Retrospective Studies
80 rdf:type schema:DefinedTerm
81 N4124ff009cc84198b40facfc4a9d12d2 schema:name readcube_id
82 schema:value 6155976ac654ad8ff5c0b6242d7bc2a3f7f1adb560187a7a7211371178d83d58
83 rdf:type schema:PropertyValue
84 N44f3f7f51a284669bb7e4ae2cca8f80a rdf:first sg:person.01113557312.13
85 rdf:rest N551495d3219b44f6bc88a8b6631c9301
86 N47a83e93d37c4506bcd299c4bb189bd7 rdf:first sg:person.01357752371.70
87 rdf:rest rdf:nil
88 N4fcb2f00c49c4ccca2195d68ccdcced4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
89 schema:name Predictive Value of Tests
90 rdf:type schema:DefinedTerm
91 N5279b5ca67ee4ec0bd105ad219d55967 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
92 schema:name Humans
93 rdf:type schema:DefinedTerm
94 N551495d3219b44f6bc88a8b6631c9301 rdf:first sg:person.0707232342.18
95 rdf:rest N47a83e93d37c4506bcd299c4bb189bd7
96 N5aebc503688b406baa8f0975807a422f schema:name Springer Nature - SN SciGraph project
97 rdf:type schema:Organization
98 N5e7fdef9fc5641fab183caa2b9b9a374 schema:issueNumber 7
99 rdf:type schema:PublicationIssue
100 N616140f5bea946e58b19629d2bf68256 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
101 schema:name C-Reactive Protein
102 rdf:type schema:DefinedTerm
103 N6c737c524ff54e7bbc51f6f92a0f5be9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
104 schema:name Prosthesis-Related Infections
105 rdf:type schema:DefinedTerm
106 N7ba9cbd23ae84ccb97e0c3e263f8caa7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
107 schema:name ROC Curve
108 rdf:type schema:DefinedTerm
109 Naa8d53ea48b54d68ae90ac774781cfdf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
110 schema:name Reoperation
111 rdf:type schema:DefinedTerm
112 Nb5a7700467d949b1be7182711923ab94 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
113 schema:name Arthroplasty, Replacement, Knee
114 rdf:type schema:DefinedTerm
115 Nc35be40154164e099d47bf4dcbc71e91 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
116 schema:name Female
117 rdf:type schema:DefinedTerm
118 Ncba249d9173348d2a62a7a030b407b97 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
119 schema:name Recurrence
120 rdf:type schema:DefinedTerm
121 Nd0a87ca885fa4fa3a0fcbf2b50cb510a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
122 schema:name Follow-Up Studies
123 rdf:type schema:DefinedTerm
124 Nd17cb4bede2843f3b29a35a13410a050 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
125 schema:name Male
126 rdf:type schema:DefinedTerm
127 Nd1a5e7d0de9a4742866e8910f884ef68 schema:name dimensions_id
128 schema:value pub.1020427925
129 rdf:type schema:PropertyValue
130 Nd2f900fe49384b5eaa0c12a8897b8dbc schema:name doi
131 schema:value 10.1007/s11999-009-0742-9
132 rdf:type schema:PropertyValue
133 Nd812146dbe164a9bab98406dc7366b94 schema:name pubmed_id
134 schema:value 19241115
135 rdf:type schema:PropertyValue
136 Nda5e507043b24e1a81fe66cf64613921 schema:name nlm_unique_id
137 schema:value 0075674
138 rdf:type schema:PropertyValue
139 Ndb247c288b6741d193b545ec60828e57 schema:volumeNumber 467
140 rdf:type schema:PublicationVolume
141 Ne343db3010b94d47bd10df046cf9b295 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
142 schema:name Sensitivity and Specificity
143 rdf:type schema:DefinedTerm
144 Ne6710e237fef4a588213d2e31dd96a2d rdf:first sg:person.0766260352.99
145 rdf:rest N44f3f7f51a284669bb7e4ae2cca8f80a
146 Ne769c92fd72241f9bdc33ade976f5cbf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
147 schema:name Biomarkers
148 rdf:type schema:DefinedTerm
149 Nea5ec6a3c0ef41458f416a7105f09544 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
150 schema:name Prognosis
151 rdf:type schema:DefinedTerm
152 Nef7dbc617d764b89af17f3d42d4695de rdf:first sg:person.01311370364.52
153 rdf:rest Ne6710e237fef4a588213d2e31dd96a2d
154 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
155 schema:name Medical and Health Sciences
156 rdf:type schema:DefinedTerm
157 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
158 schema:name Clinical Sciences
159 rdf:type schema:DefinedTerm
160 sg:journal.1007212 schema:issn 0009-921X
161 1528-1132
162 schema:name Clinical Orthopaedics and Related Research®
163 rdf:type schema:Periodical
164 sg:person.01113557312.13 schema:affiliation https://www.grid.ac/institutes/grid.265008.9
165 schema:familyName Seeley
166 schema:givenName Mark
167 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01113557312.13
168 rdf:type schema:Person
169 sg:person.01311370364.52 schema:affiliation https://www.grid.ac/institutes/grid.265008.9
170 schema:familyName Ghanem
171 schema:givenName Elie
172 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01311370364.52
173 rdf:type schema:Person
174 sg:person.01357752371.70 schema:affiliation https://www.grid.ac/institutes/grid.265008.9
175 schema:familyName Parvizi
176 schema:givenName Javad
177 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01357752371.70
178 rdf:type schema:Person
179 sg:person.0707232342.18 schema:affiliation https://www.grid.ac/institutes/grid.265008.9
180 schema:familyName Joshi
181 schema:givenName Ashish
182 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0707232342.18
183 rdf:type schema:Person
184 sg:person.0766260352.99 schema:affiliation https://www.grid.ac/institutes/grid.265008.9
185 schema:familyName Azzam
186 schema:givenName Khalid
187 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0766260352.99
188 rdf:type schema:Person
189 sg:pub.10.1385/ir:30:3:261 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029591810
190 https://doi.org/10.1385/ir:30:3:261
191 rdf:type schema:CreativeWork
192 https://app.dimensions.ai/details/publication/pub.1074808514 schema:CreativeWork
193 https://app.dimensions.ai/details/publication/pub.1077510585 schema:CreativeWork
194 https://doi.org/10.1016/j.amjmed.2004.06.022 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043739815
195 rdf:type schema:CreativeWork
196 https://doi.org/10.1016/j.arth.2006.01.028 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048540176
197 rdf:type schema:CreativeWork
198 https://doi.org/10.1016/s0272-2712(18)30408-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1082752492
199 rdf:type schema:CreativeWork
200 https://doi.org/10.1016/s0736-4679(97)00197-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010999213
201 rdf:type schema:CreativeWork
202 https://doi.org/10.1016/s0883-5403(98)90071-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024769941
203 rdf:type schema:CreativeWork
204 https://doi.org/10.1056/nejm198701293160509 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023363589
205 rdf:type schema:CreativeWork
206 https://doi.org/10.1056/nejmoa061588 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005008919
207 rdf:type schema:CreativeWork
208 https://doi.org/10.1086/374554 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025185899
209 rdf:type schema:CreativeWork
210 https://doi.org/10.1097/00003086-198404000-00015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060160620
211 rdf:type schema:CreativeWork
212 https://doi.org/10.1097/00003086-199610000-00016 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060166566
213 rdf:type schema:CreativeWork
214 https://doi.org/10.1097/00003086-199712000-00003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060167117
215 rdf:type schema:CreativeWork
216 https://doi.org/10.1097/01.blo.0000147713.64235.73 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017486238
217 rdf:type schema:CreativeWork
218 https://doi.org/10.1097/01.blo.0000218727.14097.d5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041765029
219 rdf:type schema:CreativeWork
220 https://doi.org/10.1097/blo.0b013e318157eb1e schema:sameAs https://app.dimensions.ai/details/publication/pub.1077510585
221 rdf:type schema:CreativeWork
222 https://doi.org/10.1302/0301-620x.78b3.0780431 schema:sameAs https://app.dimensions.ai/details/publication/pub.1082888034
223 rdf:type schema:CreativeWork
224 https://doi.org/10.1302/0301-620x.86b5.14887 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017256548
225 rdf:type schema:CreativeWork
226 https://doi.org/10.1302/0301-620x.89b1.17485 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021659852
227 rdf:type schema:CreativeWork
228 https://doi.org/10.2106/00004623-198365080-00008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1068888305
229 rdf:type schema:CreativeWork
230 https://doi.org/10.2106/00004623-199604000-00005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1068892334
231 rdf:type schema:CreativeWork
232 https://doi.org/10.2106/00004623-200011000-00006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1068894068
233 rdf:type schema:CreativeWork
234 https://doi.org/10.2106/00004623-200707000-00001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1068897883
235 rdf:type schema:CreativeWork
236 https://doi.org/10.2106/jbjs.d.02602 schema:sameAs https://app.dimensions.ai/details/publication/pub.1068899467
237 rdf:type schema:CreativeWork
238 https://doi.org/10.2106/jbjs.f.00609 schema:sameAs https://app.dimensions.ai/details/publication/pub.1068900155
239 rdf:type schema:CreativeWork
240 https://www.grid.ac/institutes/grid.265008.9 schema:alternateName Thomas Jefferson University
241 schema:name Rothman Institute of Orthopedics at Jefferson, Thomas Jefferson University, 925 Chestnut Street, 19107, Philadelphia, PA, USA
242 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...