Obese Diabetic Patients are at Substantial Risk for Deep Infection after Primary TKA View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2009-06

AUTHORS

Michelle M. Dowsey, Peter F. M. Choong

ABSTRACT

We conducted a prospective study of 1214 consecutive primary TKAs to compare the deep prosthetic infection rate between obese and nonobese patients during the first 12 months after surgery. We also sought to determine whether patient or surgical variables such as comorbidities, age, gender, blood transfusion, use of surgical drains, and antibiotic-impregnated cement were predictors of subsequent prosthetic infection after primary TKA. The overall prosthetic infection rate was 1.5% (n = 18). The odds for a deep prosthetic infection were greater in patients with morbid obesity (odds ratio [OR], 8.96; 95% confidence interval, 1.59-50.63) and diabetes (OR, 6.87; 95% confidence interval, 2.42-19.56). Men were more likely to have a prosthetic infection develop than women (OR, 5.93; 95% confidence interval, 1.95-18.04) and the prosthetic infection rate was lower (OR, 0.24; 95% confidence interval, 0.06-0.95) in patients when a surgical drain was used. There were no prosthetic infections in patients with diabetes who were not obese. This compares with 11 prosthetic infections in patients who were obese and diabetic and four prosthetic infections in patients who were obese but not diabetic. Morbid obesity and obesity combined with diabetes are risk factors for periprosthetic infection after TKA. LEVEL OF EVIDENCE: Level II, prognostic study. See the Guidelines for Authors for a complete description of levels of evidence. More... »

PAGES

1577-1581

References to SciGraph publications

  • 2008-01. Obesity is a Major Risk Factor for Prosthetic Infection after Primary Hip Arthroplasty in CLINICAL ORTHOPAEDICS AND RELATED RESEARCH®
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s11999-008-0551-6

    DOI

    http://dx.doi.org/10.1007/s11999-008-0551-6

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1037154340

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/18841430


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Clinical Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Medical and Health Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Age Factors", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Aged", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Arthroplasty, Replacement, Knee", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Blood Transfusion", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Bone Cements", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Chi-Square Distribution", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Confidence Intervals", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Diabetes Mellitus", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Drainage", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Female", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Humans", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Male", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Obesity", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Odds Ratio", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Prospective Studies", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Prosthesis-Related Infections", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Retrospective Studies", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Risk Factors", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Sex Factors", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "University of Melbourne", 
              "id": "https://www.grid.ac/institutes/grid.1008.9", 
              "name": [
                "Department of Orthopaedics, St Vincent\u2019s Hospital Melbourne, Fitzroy, PO Box 2900, 3065, Melbourne, VIC, Australia", 
                "Department of Surgery, Melbourne University, Melbourne, Australia"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Dowsey", 
            "givenName": "Michelle M.", 
            "id": "sg:person.0602320707.29", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0602320707.29"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Melbourne", 
              "id": "https://www.grid.ac/institutes/grid.1008.9", 
              "name": [
                "Department of Orthopaedics, St Vincent\u2019s Hospital Melbourne, Fitzroy, PO Box 2900, 3065, Melbourne, VIC, Australia", 
                "Department of Surgery, Melbourne University, Melbourne, Australia"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Choong", 
            "givenName": "Peter F. M.", 
            "id": "sg:person.010622362137.43", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010622362137.43"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "https://doi.org/10.1016/s0140-6736(03)13640-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000237247"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0140-6736(03)13640-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000237247"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1302/0301-620x.88b3.16488", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000570360"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s1098-3597(07)80018-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001260468"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.arth.2005.04.023", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001622200"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.arth.2005.04.023", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001622200"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00129334-200410000-00013", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003807433"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00129334-200410000-00013", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003807433"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00129334-200410000-00013", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003807433"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.mcna.2007.06.002", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006658220"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.arth.2006.09.002", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007946942"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/014860719802200277", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010371941"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0753-3322(00)88855-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016998947"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1054/arth.2001.19159", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023153132"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1086/501620", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027071356"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1445-2197.2008.04554.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034178896"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.arth.2007.05.052", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036828800"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s11999-007-0016-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046073620", 
              "https://doi.org/10.1007/s11999-007-0016-3"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s11999-007-0016-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046073620", 
              "https://doi.org/10.1007/s11999-007-0016-3"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1007/s11999-007-0016-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046073620"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/01.blo.0000156479.97488.a2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047406746"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/01.blo.0000156479.97488.a2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047406746"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/01.blo.0000156479.97488.a2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047406746"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00003086-199011000-00023", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060163901"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00003086-199011000-00023", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060163901"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00003086-199011000-00023", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060163901"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00003086-200111000-00003", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060168938"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00003086-200111000-00003", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060168938"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00003086-200111000-00003", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060168938"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2106/00004623-199401000-00005", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1068891631"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2106/00004623-199812000-00006", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1068893233"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2106/00004623-200406000-00005", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1068896244"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2106/00004623-200701000-00005", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1068897628"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2106/jbjs.f.00163", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1068900006"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2106/jbjs.f.00163", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1068900006"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2106/jbjs.f.00163", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1068900006"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1074252988", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.5694/j.1326-5377.1999.tb126882.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1074252988"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.5694/j.1326-5377.1999.tb126882.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1074252988"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.5694/j.1326-5377.1999.tb126882.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1074252988"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1074364313", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1075052364", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1083065505", 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2009-06", 
        "datePublishedReg": "2009-06-01", 
        "description": "We conducted a prospective study of 1214 consecutive primary TKAs to compare the deep prosthetic infection rate between obese and nonobese patients during the first 12 months after surgery. We also sought to determine whether patient or surgical variables such as comorbidities, age, gender, blood transfusion, use of surgical drains, and antibiotic-impregnated cement were predictors of subsequent prosthetic infection after primary TKA. The overall prosthetic infection rate was 1.5% (n = 18). The odds for a deep prosthetic infection were greater in patients with morbid obesity (odds ratio [OR], 8.96; 95% confidence interval, 1.59-50.63) and diabetes (OR, 6.87; 95% confidence interval, 2.42-19.56). Men were more likely to have a prosthetic infection develop than women (OR, 5.93; 95% confidence interval, 1.95-18.04) and the prosthetic infection rate was lower (OR, 0.24; 95% confidence interval, 0.06-0.95) in patients when a surgical drain was used. There were no prosthetic infections in patients with diabetes who were not obese. This compares with 11 prosthetic infections in patients who were obese and diabetic and four prosthetic infections in patients who were obese but not diabetic. Morbid obesity and obesity combined with diabetes are risk factors for periprosthetic infection after TKA.\nLEVEL OF EVIDENCE: Level II, prognostic study. See the Guidelines for Authors for a complete description of levels of evidence.", 
        "genre": "research_article", 
        "id": "sg:pub.10.1007/s11999-008-0551-6", 
        "inLanguage": [
          "en"
        ], 
        "isAccessibleForFree": true, 
        "isPartOf": [
          {
            "id": "sg:journal.1007212", 
            "issn": [
              "0009-921X", 
              "1528-1132"
            ], 
            "name": "Clinical Orthopaedics and Related Research\u00ae", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "6", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "467"
          }
        ], 
        "name": "Obese Diabetic Patients are at Substantial Risk for Deep Infection after Primary TKA", 
        "pagination": "1577-1581", 
        "productId": [
          {
            "name": "readcube_id", 
            "type": "PropertyValue", 
            "value": [
              "b0fd9d5758cb36e6a7353b58e87a3571093d6f5749443ee3694904a16f03831f"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "18841430"
            ]
          }, 
          {
            "name": "nlm_unique_id", 
            "type": "PropertyValue", 
            "value": [
              "0075674"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1007/s11999-008-0551-6"
            ]
          }, 
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1037154340"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1007/s11999-008-0551-6", 
          "https://app.dimensions.ai/details/publication/pub.1037154340"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2019-04-10T17:34", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8672_00000523.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "http://link.springer.com/10.1007%2Fs11999-008-0551-6"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s11999-008-0551-6'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s11999-008-0551-6'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s11999-008-0551-6'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s11999-008-0551-6'


     

    This table displays all metadata directly associated to this object as RDF triples.

    234 TRIPLES      21 PREDICATES      76 URIs      40 LITERALS      28 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1007/s11999-008-0551-6 schema:about N008ff92b43ed4fe5a9353817af2e492c
    2 N0edd087e4fae4b98a06e6f543e5406c8
    3 N1a854234416d464099c943e583162377
    4 N301bc470f9324781a2fb0470cb032693
    5 N399e52149c1c441493f8c9c3309a67c0
    6 N42c42d32e1e543b7a754208d5bf22f16
    7 N4f1036345efd4ae0bc92871ff8bf3d2d
    8 N5987cfb65f9b41deb64f120341aec24d
    9 N5d40e7fbce9f4b96a9c53e98969d9d13
    10 N61f7068abfb24152b672ad1ed729ffff
    11 N679982141f724e42ae3c12238b8179d8
    12 N6ce1e534eb614896a9f49258c3eaf3bb
    13 N735dedb74f88461c9a61f4c225e57dc9
    14 N85805857d500427b96120bf0678d894b
    15 N8d5cb87eafb44a52be854065f15e05a2
    16 N9e7090fb927847508f249b6357d9f506
    17 Naae6144786974ddba27d96e06a3dace2
    18 Nabf17349bbd442f0940a5f56cc21c049
    19 Nc383ffbaecdb46d5b31ac4c1a3e12988
    20 anzsrc-for:11
    21 anzsrc-for:1103
    22 schema:author Nb79d5baa2c4e4467b53e8a53b6e959f4
    23 schema:citation sg:pub.10.1007/s11999-007-0016-3
    24 https://app.dimensions.ai/details/publication/pub.1074252988
    25 https://app.dimensions.ai/details/publication/pub.1074364313
    26 https://app.dimensions.ai/details/publication/pub.1075052364
    27 https://app.dimensions.ai/details/publication/pub.1083065505
    28 https://doi.org/10.1007/s11999-007-0016-3
    29 https://doi.org/10.1016/j.arth.2005.04.023
    30 https://doi.org/10.1016/j.arth.2006.09.002
    31 https://doi.org/10.1016/j.arth.2007.05.052
    32 https://doi.org/10.1016/j.mcna.2007.06.002
    33 https://doi.org/10.1016/s0140-6736(03)13640-9
    34 https://doi.org/10.1016/s0753-3322(00)88855-1
    35 https://doi.org/10.1016/s1098-3597(07)80018-4
    36 https://doi.org/10.1054/arth.2001.19159
    37 https://doi.org/10.1086/501620
    38 https://doi.org/10.1097/00003086-199011000-00023
    39 https://doi.org/10.1097/00003086-200111000-00003
    40 https://doi.org/10.1097/00129334-200410000-00013
    41 https://doi.org/10.1097/01.blo.0000156479.97488.a2
    42 https://doi.org/10.1111/j.1445-2197.2008.04554.x
    43 https://doi.org/10.1177/014860719802200277
    44 https://doi.org/10.1302/0301-620x.88b3.16488
    45 https://doi.org/10.2106/00004623-199401000-00005
    46 https://doi.org/10.2106/00004623-199812000-00006
    47 https://doi.org/10.2106/00004623-200406000-00005
    48 https://doi.org/10.2106/00004623-200701000-00005
    49 https://doi.org/10.2106/jbjs.f.00163
    50 https://doi.org/10.5694/j.1326-5377.1999.tb126882.x
    51 schema:datePublished 2009-06
    52 schema:datePublishedReg 2009-06-01
    53 schema:description We conducted a prospective study of 1214 consecutive primary TKAs to compare the deep prosthetic infection rate between obese and nonobese patients during the first 12 months after surgery. We also sought to determine whether patient or surgical variables such as comorbidities, age, gender, blood transfusion, use of surgical drains, and antibiotic-impregnated cement were predictors of subsequent prosthetic infection after primary TKA. The overall prosthetic infection rate was 1.5% (n = 18). The odds for a deep prosthetic infection were greater in patients with morbid obesity (odds ratio [OR], 8.96; 95% confidence interval, 1.59-50.63) and diabetes (OR, 6.87; 95% confidence interval, 2.42-19.56). Men were more likely to have a prosthetic infection develop than women (OR, 5.93; 95% confidence interval, 1.95-18.04) and the prosthetic infection rate was lower (OR, 0.24; 95% confidence interval, 0.06-0.95) in patients when a surgical drain was used. There were no prosthetic infections in patients with diabetes who were not obese. This compares with 11 prosthetic infections in patients who were obese and diabetic and four prosthetic infections in patients who were obese but not diabetic. Morbid obesity and obesity combined with diabetes are risk factors for periprosthetic infection after TKA. LEVEL OF EVIDENCE: Level II, prognostic study. See the Guidelines for Authors for a complete description of levels of evidence.
    54 schema:genre research_article
    55 schema:inLanguage en
    56 schema:isAccessibleForFree true
    57 schema:isPartOf Nadd947861e4f491e8f20152893b4a4f5
    58 Ne9e34580103a45ecaba4ac74b51358af
    59 sg:journal.1007212
    60 schema:name Obese Diabetic Patients are at Substantial Risk for Deep Infection after Primary TKA
    61 schema:pagination 1577-1581
    62 schema:productId N5671f29de0454369adc9fd4932f9039a
    63 N61a686e92f544a6eb987d6514f417ed3
    64 N8e9bc91165974727a1dee51c40e3f693
    65 Nbfd320b2b0a74fe9872483aa088bee05
    66 Ne5d81d8217d54cc6b9b35726733e45da
    67 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037154340
    68 https://doi.org/10.1007/s11999-008-0551-6
    69 schema:sdDatePublished 2019-04-10T17:34
    70 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    71 schema:sdPublisher Ndcbb79e6ec9d4deb8221ba82e5d49e25
    72 schema:url http://link.springer.com/10.1007%2Fs11999-008-0551-6
    73 sgo:license sg:explorer/license/
    74 sgo:sdDataset articles
    75 rdf:type schema:ScholarlyArticle
    76 N008ff92b43ed4fe5a9353817af2e492c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    77 schema:name Age Factors
    78 rdf:type schema:DefinedTerm
    79 N0edd087e4fae4b98a06e6f543e5406c8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    80 schema:name Blood Transfusion
    81 rdf:type schema:DefinedTerm
    82 N189fcaaa880f4caa9aba8c9295ddabd3 rdf:first sg:person.010622362137.43
    83 rdf:rest rdf:nil
    84 N1a854234416d464099c943e583162377 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    85 schema:name Bone Cements
    86 rdf:type schema:DefinedTerm
    87 N301bc470f9324781a2fb0470cb032693 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    88 schema:name Odds Ratio
    89 rdf:type schema:DefinedTerm
    90 N399e52149c1c441493f8c9c3309a67c0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    91 schema:name Confidence Intervals
    92 rdf:type schema:DefinedTerm
    93 N42c42d32e1e543b7a754208d5bf22f16 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    94 schema:name Humans
    95 rdf:type schema:DefinedTerm
    96 N4f1036345efd4ae0bc92871ff8bf3d2d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    97 schema:name Female
    98 rdf:type schema:DefinedTerm
    99 N5671f29de0454369adc9fd4932f9039a schema:name nlm_unique_id
    100 schema:value 0075674
    101 rdf:type schema:PropertyValue
    102 N5987cfb65f9b41deb64f120341aec24d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    103 schema:name Diabetes Mellitus
    104 rdf:type schema:DefinedTerm
    105 N5d40e7fbce9f4b96a9c53e98969d9d13 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    106 schema:name Prospective Studies
    107 rdf:type schema:DefinedTerm
    108 N61a686e92f544a6eb987d6514f417ed3 schema:name readcube_id
    109 schema:value b0fd9d5758cb36e6a7353b58e87a3571093d6f5749443ee3694904a16f03831f
    110 rdf:type schema:PropertyValue
    111 N61f7068abfb24152b672ad1ed729ffff schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    112 schema:name Male
    113 rdf:type schema:DefinedTerm
    114 N679982141f724e42ae3c12238b8179d8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    115 schema:name Prosthesis-Related Infections
    116 rdf:type schema:DefinedTerm
    117 N6ce1e534eb614896a9f49258c3eaf3bb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    118 schema:name Obesity
    119 rdf:type schema:DefinedTerm
    120 N735dedb74f88461c9a61f4c225e57dc9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    121 schema:name Arthroplasty, Replacement, Knee
    122 rdf:type schema:DefinedTerm
    123 N85805857d500427b96120bf0678d894b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    124 schema:name Drainage
    125 rdf:type schema:DefinedTerm
    126 N8d5cb87eafb44a52be854065f15e05a2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    127 schema:name Aged
    128 rdf:type schema:DefinedTerm
    129 N8e9bc91165974727a1dee51c40e3f693 schema:name pubmed_id
    130 schema:value 18841430
    131 rdf:type schema:PropertyValue
    132 N9e7090fb927847508f249b6357d9f506 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    133 schema:name Chi-Square Distribution
    134 rdf:type schema:DefinedTerm
    135 Naae6144786974ddba27d96e06a3dace2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    136 schema:name Risk Factors
    137 rdf:type schema:DefinedTerm
    138 Nabf17349bbd442f0940a5f56cc21c049 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    139 schema:name Retrospective Studies
    140 rdf:type schema:DefinedTerm
    141 Nadd947861e4f491e8f20152893b4a4f5 schema:issueNumber 6
    142 rdf:type schema:PublicationIssue
    143 Nb79d5baa2c4e4467b53e8a53b6e959f4 rdf:first sg:person.0602320707.29
    144 rdf:rest N189fcaaa880f4caa9aba8c9295ddabd3
    145 Nbfd320b2b0a74fe9872483aa088bee05 schema:name doi
    146 schema:value 10.1007/s11999-008-0551-6
    147 rdf:type schema:PropertyValue
    148 Nc383ffbaecdb46d5b31ac4c1a3e12988 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    149 schema:name Sex Factors
    150 rdf:type schema:DefinedTerm
    151 Ndcbb79e6ec9d4deb8221ba82e5d49e25 schema:name Springer Nature - SN SciGraph project
    152 rdf:type schema:Organization
    153 Ne5d81d8217d54cc6b9b35726733e45da schema:name dimensions_id
    154 schema:value pub.1037154340
    155 rdf:type schema:PropertyValue
    156 Ne9e34580103a45ecaba4ac74b51358af schema:volumeNumber 467
    157 rdf:type schema:PublicationVolume
    158 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
    159 schema:name Medical and Health Sciences
    160 rdf:type schema:DefinedTerm
    161 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
    162 schema:name Clinical Sciences
    163 rdf:type schema:DefinedTerm
    164 sg:journal.1007212 schema:issn 0009-921X
    165 1528-1132
    166 schema:name Clinical Orthopaedics and Related Research®
    167 rdf:type schema:Periodical
    168 sg:person.010622362137.43 schema:affiliation https://www.grid.ac/institutes/grid.1008.9
    169 schema:familyName Choong
    170 schema:givenName Peter F. M.
    171 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010622362137.43
    172 rdf:type schema:Person
    173 sg:person.0602320707.29 schema:affiliation https://www.grid.ac/institutes/grid.1008.9
    174 schema:familyName Dowsey
    175 schema:givenName Michelle M.
    176 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0602320707.29
    177 rdf:type schema:Person
    178 sg:pub.10.1007/s11999-007-0016-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046073620
    179 https://doi.org/10.1007/s11999-007-0016-3
    180 rdf:type schema:CreativeWork
    181 https://app.dimensions.ai/details/publication/pub.1074252988 schema:CreativeWork
    182 https://app.dimensions.ai/details/publication/pub.1074364313 schema:CreativeWork
    183 https://app.dimensions.ai/details/publication/pub.1075052364 schema:CreativeWork
    184 https://app.dimensions.ai/details/publication/pub.1083065505 schema:CreativeWork
    185 https://doi.org/10.1007/s11999-007-0016-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046073620
    186 rdf:type schema:CreativeWork
    187 https://doi.org/10.1016/j.arth.2005.04.023 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001622200
    188 rdf:type schema:CreativeWork
    189 https://doi.org/10.1016/j.arth.2006.09.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007946942
    190 rdf:type schema:CreativeWork
    191 https://doi.org/10.1016/j.arth.2007.05.052 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036828800
    192 rdf:type schema:CreativeWork
    193 https://doi.org/10.1016/j.mcna.2007.06.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006658220
    194 rdf:type schema:CreativeWork
    195 https://doi.org/10.1016/s0140-6736(03)13640-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000237247
    196 rdf:type schema:CreativeWork
    197 https://doi.org/10.1016/s0753-3322(00)88855-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016998947
    198 rdf:type schema:CreativeWork
    199 https://doi.org/10.1016/s1098-3597(07)80018-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001260468
    200 rdf:type schema:CreativeWork
    201 https://doi.org/10.1054/arth.2001.19159 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023153132
    202 rdf:type schema:CreativeWork
    203 https://doi.org/10.1086/501620 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027071356
    204 rdf:type schema:CreativeWork
    205 https://doi.org/10.1097/00003086-199011000-00023 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060163901
    206 rdf:type schema:CreativeWork
    207 https://doi.org/10.1097/00003086-200111000-00003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060168938
    208 rdf:type schema:CreativeWork
    209 https://doi.org/10.1097/00129334-200410000-00013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003807433
    210 rdf:type schema:CreativeWork
    211 https://doi.org/10.1097/01.blo.0000156479.97488.a2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047406746
    212 rdf:type schema:CreativeWork
    213 https://doi.org/10.1111/j.1445-2197.2008.04554.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1034178896
    214 rdf:type schema:CreativeWork
    215 https://doi.org/10.1177/014860719802200277 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010371941
    216 rdf:type schema:CreativeWork
    217 https://doi.org/10.1302/0301-620x.88b3.16488 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000570360
    218 rdf:type schema:CreativeWork
    219 https://doi.org/10.2106/00004623-199401000-00005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1068891631
    220 rdf:type schema:CreativeWork
    221 https://doi.org/10.2106/00004623-199812000-00006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1068893233
    222 rdf:type schema:CreativeWork
    223 https://doi.org/10.2106/00004623-200406000-00005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1068896244
    224 rdf:type schema:CreativeWork
    225 https://doi.org/10.2106/00004623-200701000-00005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1068897628
    226 rdf:type schema:CreativeWork
    227 https://doi.org/10.2106/jbjs.f.00163 schema:sameAs https://app.dimensions.ai/details/publication/pub.1068900006
    228 rdf:type schema:CreativeWork
    229 https://doi.org/10.5694/j.1326-5377.1999.tb126882.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1074252988
    230 rdf:type schema:CreativeWork
    231 https://www.grid.ac/institutes/grid.1008.9 schema:alternateName University of Melbourne
    232 schema:name Department of Orthopaedics, St Vincent’s Hospital Melbourne, Fitzroy, PO Box 2900, 3065, Melbourne, VIC, Australia
    233 Department of Surgery, Melbourne University, Melbourne, Australia
    234 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...