JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/09", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Engineering", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0904", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Chemical Engineering", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Pharmaceutics, Faculty of Pharmacy, Bahauddin Zakariya University, P.O.Box: 60800, Multan, Pakistan", 
          "id": "http://www.grid.ac/institutes/grid.411501.0", 
          "name": [
            "Department of Pharmaceutics, Faculty of Pharmacy, Bahauddin Zakariya University, P.O.Box: 60800, Multan, Pakistan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Akhtar", 
        "givenName": "Muhammad Faheem", 
        "id": "sg:person.0757622353.40", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0757622353.40"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Pharmaceutics, Faculty of Pharmacy, Bahauddin Zakariya University, P.O.Box: 60800, Multan, Pakistan", 
          "id": "http://www.grid.ac/institutes/grid.411501.0", 
          "name": [
            "Department of Pharmaceutics, Faculty of Pharmacy, Bahauddin Zakariya University, P.O.Box: 60800, Multan, Pakistan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ashraf", 
        "givenName": "Hira", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Bahauddin Zakariya University Multan, Bahauddin, Pakistan", 
          "id": "http://www.grid.ac/institutes/grid.411501.0", 
          "name": [
            "Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Bahauddin Zakariya University Multan, Bahauddin, Pakistan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Uzair", 
        "givenName": "Muhammad", 
        "id": "sg:person.012456105615.43", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012456105615.43"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Center for Synthetic Biology, College of Chemical and Biological Engineering, Hangzhou, China", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Center for Synthetic Biology, College of Chemical and Biological Engineering, Hangzhou, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ahmad", 
        "givenName": "Shabbir", 
        "id": "sg:person.014755477331.12", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014755477331.12"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Faculty of Pharmacy, GOVT. College University, Faisalabad, Pakistan", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Faculty of Pharmacy, GOVT. College University, Faisalabad, Pakistan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rasul", 
        "givenName": "Akhtar", 
        "id": "sg:person.01032376613.45", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01032376613.45"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Faculty of Pharmacy, GOVT. College University, Faisalabad, Pakistan", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Faculty of Pharmacy, GOVT. College University, Faisalabad, Pakistan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Abbas", 
        "givenName": "Ghulam", 
        "id": "sg:person.013205642411.68", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013205642411.68"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Faculty of Pharmacy, GOVT. College University, Faisalabad, Pakistan", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Faculty of Pharmacy, GOVT. College University, Faisalabad, Pakistan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shah", 
        "givenName": "Shahid", 
        "id": "sg:person.010510267713.86", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010510267713.86"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Pharmaceutics, Faculty of Pharmacy, Bahauddin Zakariya University, P.O.Box: 60800, Multan, Pakistan", 
          "id": "http://www.grid.ac/institutes/grid.411501.0", 
          "name": [
            "Department of Pharmaceutics, Faculty of Pharmacy, Bahauddin Zakariya University, P.O.Box: 60800, Multan, Pakistan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hanif", 
        "givenName": "Muhammad", 
        "id": "sg:person.015244306020.19", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015244306020.19"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/s11998-019-00290-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1123790725", 
          "https://doi.org/10.1007/s11998-019-00290-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1208/pt0803053", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039364911", 
          "https://doi.org/10.1208/pt0803053"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1023/a:1015800606298", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027556191", 
          "https://doi.org/10.1023/a:1015800606298"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1208/s12248-015-9723-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011773335", 
          "https://doi.org/10.1208/s12248-015-9723-y"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2021-10-19", 
    "datePublishedReg": "2021-10-19", 
    "description": "The present study aimed to design and evaluate controlled porosity osmotic pump (CPOP) tablets of enalapril maleate (ENP) being used for the treatment of hypertension. D-optimal response surface design was used, considering cellulose acetate and osmotic agents (lactose and fructose) as variables while physicochemical parameters of tablets were taken as responses. The asymmetric, leachable membrane of cellulose acetate on ENP tablets was applied and an increase in the thickness of core tablets from 5 \u00b1 0.01 to 5.4 \u00b1 0.17 mm was observed. The average weight of all CPOP formulations ranged from 376.7 \u00b1 0.4 to 389.1 \u00b1 0.3 mg and hardness was 6.2 \u00b1 0.02 to 6.32 \u00b1 0.06 Kg/cm2. The friability of all formulations was less than 1%. 89.53 \u00b1 1.05% of ENP release was observed in phosphate buffer pH 6.8 after 12 h. Due to the smallest AIC (Akaike information criteria) and the greatest r2 values, zero-order release kinetics model with non-Fickian diffusion behavior was observed in all proposed formulations. f1 (difference factor) values were 1.28 \u00b1 0.06 to 12.64 \u00b1 0.41% and f2 (similarity factor) values were 59.75 \u00b1 0.24 to 94.03 \u00b1 1.36% in the same dissolution medium. pH-independent behavior was observed in pH-responsive study. Dissolution efficiency (DE) ranged from 51.49 \u00b1 0.23 to 53.52 \u00b1 0.52% and mean dissolution time (MDT) values ranged from 5.27 \u00b1 0.05 to 5.59 \u00b1 0.23 h. No interaction between the ingredients was found in FTIR analysis. The optimized formulation with improved drug release property was found stable in the accelerated stability study of six months. CPOP tablets of ENP can be considered as an effective substitute for immediate-release tablets to control hypertension in chronic conditions.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/s11998-021-00536-3", 
    "inLanguage": "en", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1412839", 
        "issn": [
          "1945-9645", 
          "1742-0261"
        ], 
        "name": "Journal of Coatings Technology and Research", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "2", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "19"
      }
    ], 
    "keywords": [
      "zero-order release kinetics model", 
      "non-Fickian diffusion behavior", 
      "optimal response surface design", 
      "porosity osmotic pump tablets", 
      "dissolution efficiency", 
      "response surface design", 
      "drug release properties", 
      "Kg/cm2", 
      "release kinetic models", 
      "osmotic pump tablets", 
      "surface design", 
      "ENP release", 
      "diffusion behavior", 
      "CPOP tablets", 
      "kinetic model", 
      "sustained release effect", 
      "release properties", 
      "FTIR analysis", 
      "release effect", 
      "core tablet", 
      "phosphate buffer pH 6.8", 
      "mean dissolution time values", 
      "dissolution medium", 
      "buffer pH 6.8", 
      "stability studies", 
      "accelerated stability studies", 
      "formulation", 
      "hardness", 
      "R2 values", 
      "greater R2 value", 
      "cm2", 
      "cellulose", 
      "thickness", 
      "independent behavior", 
      "unique approach", 
      "behavior", 
      "immediate release tablets", 
      "pH 6.8", 
      "time values", 
      "efficiency", 
      "design", 
      "properties", 
      "effective substitute", 
      "values", 
      "pump technique", 
      "parameters", 
      "friability", 
      "osmotic agent", 
      "technique", 
      "conditions", 
      "substitute", 
      "physicochemical parameters", 
      "tablets", 
      "model", 
      "ingredients", 
      "enalapril maleate", 
      "increase", 
      "approach", 
      "effect", 
      "membrane", 
      "medium", 
      "study", 
      "analysis", 
      "release", 
      "present study", 
      "interaction", 
      "development", 
      "enalapril tablets", 
      "variables", 
      "response", 
      "weight", 
      "AIC", 
      "agents", 
      "treatment", 
      "F1 value", 
      "maleate", 
      "average weight", 
      "F2 values", 
      "months", 
      "smallest AIC", 
      "treatment of hypertension", 
      "chronic conditions", 
      "hypertension"
    ], 
    "name": "Development of leachable enalapril tablets by controlled porosity osmotic pump technique; a unique approach to enhance its sustained release effect", 
    "pagination": "497-507", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1142010051"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s11998-021-00536-3"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s11998-021-00536-3", 
      "https://app.dimensions.ai/details/publication/pub.1142010051"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-05-20T07:39", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220519/entities/gbq_results/article/article_911.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/s11998-021-00536-3"
  }
]

Download the RDF metadata as:  json-ld nt turtle xml License info

This table displays all metadata directly associated to this object as RDF triples.

212 TRIPLES      22 PREDICATES      112 URIs      100 LITERALS      6 BLANK NODES