Current Use and Promise of Urinary Markers for Urothelial Cancer View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2018-12

AUTHORS

William Tabayoyong, Ashish M. Kamat

ABSTRACT

PURPOSE OF REVIEW: We summarize the current literature regarding the available urinary biomarkers for the detection and surveillance of bladder cancer. RECENT FINDINGS: Four urinary biomarkers have FDA approval for the detection of bladder cancer; however, they have not supplanted cystoscopy and urine cytology as the gold standard. Recent technological advances in next-generation sequencing have allowed the field of urinary biomarker research to move beyond protein biomarkers and now include genomic, transcriptomic, and epigenetic panels. The search for a noninvasive, inexpensive urinary biomarker for the detection of bladder cancer that can replace cystoscopy and cytology continues. There are several promising genomic, transcriptomic, and epigenetic marker panels in development; however, these new tests require further prospective validation before widespread clinical implementation. More... »

PAGES

96

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11934-018-0857-1

DOI

http://dx.doi.org/10.1007/s11934-018-0857-1

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1107669208

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30328534


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