Ontology type: schema:ScholarlyArticle
2019-05
AUTHORSGargi Kothari, Piet Ost, Patrick Cheung, Pierre Blanchard, Alison C. Tree, Nicholas J. van As, Simon S. Lo, Drew Moghanaki, Andrew Loblaw, Shankar Siva
ABSTRACTPURPOSE OF REVIEW: Systemic therapy for patients with hormone-sensitive oligometastatic prostate cancer is non-curative and associated with toxicities. Meanwhile, this population presents unique clinical opportunities to improve outcomes, including the demonstrated benefits of radiotherapy to the primary tumor or oligometastatic sites. RECENT FINDINGS: Recently published randomized studies have demonstrated benefits with the addition of radiotherapy to the primary disease or metastatic lesions in patients with synchronous or metachronous disease. The introduction of novel PET imaging has improved the sensitivity and specificity for detecting metastatic disease and provides an opportunity to better select patients who will benefit from local therapy. The data presented in this review supports revisiting practice guidelines for patients with hormone-sensitive metastatic prostate cancer, particularly in relation to the role of radiotherapy to the primary tumor and sites of oligometastatic disease. Future trials will aim to further establish the role of metastasis-directed therapies in metachronous, synchronous, and castrate-resistant disease. More... »
PAGES43
http://scigraph.springernature.com/pub.10.1007/s11912-019-0791-5
DOIhttp://dx.doi.org/10.1007/s11912-019-0791-5
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PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/30919165
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JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s11912-019-0791-5'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s11912-019-0791-5'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s11912-019-0791-5'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s11912-019-0791-5'
This table displays all metadata directly associated to this object as RDF triples.
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98 URIs
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