Evolving Immunotherapy Approaches for Renal Cell Carcinoma View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2016-09

AUTHORS

Susanna A. Curtis, Justine V. Cohen, Harriet M. Kluger

ABSTRACT

Metastatic renal cell carcinoma (mRCC) continues to be associated with high rates of morbidity and mortality. Renal cell carcinoma (RCC) is typically resistant to cytotoxic chemotherapy, and while targeted therapies have activity and prolong progression-free and overall survival, responses are usually not durable. Modulating the immune system with cytokine therapy, vaccine therapy, cell therapy, and checkpoint inhibitors offers hope of prolonged survival. Standard and emerging immune therapy approaches and combinations of immune therapies and other modalities are reviewed. More... »

PAGES

57

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11912-016-0542-9

DOI

http://dx.doi.org/10.1007/s11912-016-0542-9

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1048484343

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/27475806


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