Nocardia Infections of the Face and Neck View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2011-01-29

AUTHORS

Alexander C. Outhred, Matthew R. Watts, Sharon C-A. Chen, Tania C. Sorrell

ABSTRACT

Involvement of the soft tissues of the face and neck by Nocardia spp. is uncommon. We review the epidemiology, clinical features, diagnosis, and management of such infections in the setting of primary cutaneous nocardiosis and disseminated disease. Although immune compromise is an important risk factor for these infections, they also occur in healthy individuals. Infection may arise through direct inoculation following injury or by hematogenous spread from a primary site, usually the lung. The rare variant of lymphocutaneous disease—cervicofacial nocardiosis—typically affects children, but can occur in adults. The diagnosis is made by conventional microscopy and culture, but radiological imaging is useful to delineate disease extent, and molecular methods are increasingly assisting the diagnosis by providing rapid detection and identification of the pathogen. Sulfonamides remain the preferred treatment for many cases and are an important component of the therapeutic armamentarium. Other therapeutic options include minocycline, the carbapenems, and linezolid. More... »

PAGES

132-140

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11908-011-0165-0

DOI

http://dx.doi.org/10.1007/s11908-011-0165-0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1042108536

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/21365376


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