Angiotensin II-mediated signal transduction pathways View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2002-03

AUTHORS

Yuji Saito, Bradford C. Berk

ABSTRACT

The renin-angiotensin system is one of the major cardiovascular systems that controls blood volume, peripheral vascular tone, and blood pressure. Recent studies indicate important roles for angiotensin II in inflammation, atherosclerosis, and congestive heart failure as well. It is gradually becoming clear that angiotensin II exerts effects on the cardiovascular system through several unique mechanisms, including the availability of two different angiotensin II receptors, recruitment of protein tyrosine kinase activity, and receptor tyrosine kinase transactivation. This review discusess the diverse mechanisms of angiotensin II-mediated signal transduction pathways and the various effects of angiotensin II on the cardiovascular system. More... »

PAGES

167-171

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11906-002-0042-1

DOI

http://dx.doi.org/10.1007/s11906-002-0042-1

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1048394544

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/11884273


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