Methodological Lessons from Clinical Trials and the Future of Microbicide Research View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2013-03

AUTHORS

Ariane van der Straten, Elizabeth T. Montgomery, Miriam Hartmann, Alexandra Minnis

ABSTRACT

Interpretation of microbicide trial results has been compromised by challenges to accurate measurement of product adherence and sexual risk behaviors. This article provides an evaluation of the methods used to measure adherence and other sensitive behaviors relevant to assessment of product safety and effectiveness in recently completed trials of vaginal and rectal microbicides. We review the strengths and limitations of existing and novel behavioral measurement strategies and provide recommendations for future trial design with the goal of facilitating the development and identification of safe and effective microbicides for HIV prevention. More... »

PAGES

89-102

References to SciGraph publications

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s11904-012-0141-9

    DOI

    http://dx.doi.org/10.1007/s11904-012-0141-9

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1019842792

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/23184582


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