Implementation Science of Pre-exposure Prophylaxis: Preparing for Public Use View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2010-09-07

AUTHORS

Kristen Underhill, Don Operario, Matthew J. Mimiaga, Margie R. Skeer, Kenneth H. Mayer

ABSTRACT

As efficacy trials of antiretroviral pre-exposure prophylaxis (PrEP) continue, a growing literature has begun anticipating the potential challenges of implementing PrEP for HIV prevention. These efforts coincide with a shift toward combination interventions for preventing HIV, which integrate biomedical, behavioral, and structural components. The optimal implementation of PrEP would exemplify this combination model, incorporating not only PrEP drugs, but also HIV testing, safety screening, behavioral interventions addressing adherence and risk behavior, and long-term monitoring. Efforts to plan for PrEP implementation therefore present an opportunity to advance the science of implementation and delivery in HIV prevention, in order to better address the challenges of scaling up combination approaches. We review the published and unpublished literature on PrEP implementation, organizing themes into five categories: scientific groundwork, regulatory and policy groundwork, stakeholder and infrastructure groundwork, delivery, and long-term monitoring. The lessons from PrEP planning can benefit the scale-up of future combination interventions. More... »

PAGES

210-219

References to SciGraph publications

  • 2009-10-14. Home testing for HIV infection in resource-limited settings in CURRENT HIV/AIDS REPORTS
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s11904-010-0062-4

    DOI

    http://dx.doi.org/10.1007/s11904-010-0062-4

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1028396408

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/20820971


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