ROSE-AHF and Lessons Learned View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2014-06-26

AUTHORS

Amit K. Jain, Horng H. Chen

ABSTRACT

Nesiritide and dopamine have been recognized for some time as potential renal adjunct therapies in the management of patients with acute heart failure (AHF). Several studies have yielded conflicting evidence of the efficacy of both medications in enhancing the renal function of patients with AHF. The Renal Optimization Strategies Evaluation (ROSE) study was a multicenter double-blind placebo controlled trial designed to assess the potential renoprotective effects of low-dose nesiritide and dopamine in AHF patients with renal dysfunction. This article will focus on previous research, summary of results, and lessons learned from the ROSE-AHF trial as well as future directions for clinical research and applications. More... »

PAGES

260-265

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11897-014-0208-6

DOI

http://dx.doi.org/10.1007/s11897-014-0208-6

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1043129398

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/24966060


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