Roles for transforming growth factor-α and transforming growth factor-ß in colorectal cancer View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2006-03

AUTHORS

Robert J. Coffey, R. Daniel Beauchamp

ABSTRACT

This review cites some of the notable advances in the last several years in our understanding of the roles of transforming growth factor (TGF)-α and TGF-ß in neoplasia in general and colorectal cancer in particular. We have chosen to concentrate on advances that have been made in the treatment of colorectal cancer by pharmacologic blockade of the epidermal growth factor receptor axis and new insights into TGF-ß signaling in colorectal cancer. More... »

PAGES

72-77

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11888-006-0005-z

DOI

http://dx.doi.org/10.1007/s11888-006-0005-z

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1005700788


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