Is There a Need for “Triple Therapy”? Role of Anticoagulation with Dual Antiplatelet Therapy in Acute Coronary Syndromes (ATLAS Study ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2013-10

AUTHORS

William L. Patrick, Charmaine Patel, Raviteja Guddeti, Aarti Narayan, Michael Maddaleni, Shankar Kumar, Kalsang Dolma, Vishnu Vardhan Serla, Maheep Sangha, Aditya Govindavarjhulla, Prashanth Saddala, Priyamvada Singh, Rim Halaby, C. Michael Gibson

ABSTRACT

In the past two decades there has been a succession of advances in the development of anticoagulant and antiplatelet therapies to be used in the treatment of ACS. Despite optimal dual antiplatelet therapy, nearly 10-12 % of patients still face a risk of death or myocardial infarction one year following PCI. This large residual risk provides the impetus for the development of more effective strategies. Dual pathway regimens that combine antiplatelets (aspirin and a thienopyridine), along with an anticoagulant such as rivaroxaban may prove to be a therapeutic option in patients with ACS. More... »

PAGES

411

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11886-013-0411-1

DOI

http://dx.doi.org/10.1007/s11886-013-0411-1

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1040710977

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/24022544


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Acute Coronary Syndrome", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Anticoagulants", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Blood Coagulation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Clinical Trials, Phase III as Topic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Dose-Response Relationship, Drug", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Drug Therapy, Combination", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Platelet Aggregation Inhibitors", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Randomized Controlled Trials as Topic", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "name": [
            "PERFUSE Study Group, Beth Israel Deaconess Medical Center, Cardiovascular Division, Department of Medicine, Harvard Medical School, 185 Pilgrim Road, Farr 319, 02215, Boston, MA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Patrick", 
        "givenName": "William L.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "PERFUSE Study Group, Beth Israel Deaconess Medical Center, Cardiovascular Division, Department of Medicine, Harvard Medical School, 185 Pilgrim Road, Farr 319, 02215, Boston, MA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Patel", 
        "givenName": "Charmaine", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "PERFUSE Study Group, Beth Israel Deaconess Medical Center, Cardiovascular Division, Department of Medicine, Harvard Medical School, 185 Pilgrim Road, Farr 319, 02215, Boston, MA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Guddeti", 
        "givenName": "Raviteja", 
        "id": "sg:person.0736166000.49", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0736166000.49"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "PERFUSE Study Group, Beth Israel Deaconess Medical Center, Cardiovascular Division, Department of Medicine, Harvard Medical School, 185 Pilgrim Road, Farr 319, 02215, Boston, MA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Narayan", 
        "givenName": "Aarti", 
        "id": "sg:person.0626206341.76", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0626206341.76"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "PERFUSE Study Group, Beth Israel Deaconess Medical Center, Cardiovascular Division, Department of Medicine, Harvard Medical School, 185 Pilgrim Road, Farr 319, 02215, Boston, MA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Maddaleni", 
        "givenName": "Michael", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "PERFUSE Study Group, Beth Israel Deaconess Medical Center, Cardiovascular Division, Department of Medicine, Harvard Medical School, 185 Pilgrim Road, Farr 319, 02215, Boston, MA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kumar", 
        "givenName": "Shankar", 
        "id": "sg:person.0742434741.28", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0742434741.28"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "PERFUSE Study Group, Beth Israel Deaconess Medical Center, Cardiovascular Division, Department of Medicine, Harvard Medical School, 185 Pilgrim Road, Farr 319, 02215, Boston, MA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Dolma", 
        "givenName": "Kalsang", 
        "id": "sg:person.01010550141.55", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01010550141.55"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "PERFUSE Study Group, Beth Israel Deaconess Medical Center, Cardiovascular Division, Department of Medicine, Harvard Medical School, 185 Pilgrim Road, Farr 319, 02215, Boston, MA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Serla", 
        "givenName": "Vishnu Vardhan", 
        "id": "sg:person.01056663341.91", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01056663341.91"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "PERFUSE Study Group, Beth Israel Deaconess Medical Center, Cardiovascular Division, Department of Medicine, Harvard Medical School, 185 Pilgrim Road, Farr 319, 02215, Boston, MA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sangha", 
        "givenName": "Maheep", 
        "id": "sg:person.01124776541.50", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01124776541.50"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "PERFUSE Study Group, Beth Israel Deaconess Medical Center, Cardiovascular Division, Department of Medicine, Harvard Medical School, 185 Pilgrim Road, Farr 319, 02215, Boston, MA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Govindavarjhulla", 
        "givenName": "Aditya", 
        "id": "sg:person.01073026366.33", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01073026366.33"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "PERFUSE Study Group, Beth Israel Deaconess Medical Center, Cardiovascular Division, Department of Medicine, Harvard Medical School, 185 Pilgrim Road, Farr 319, 02215, Boston, MA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Saddala", 
        "givenName": "Prashanth", 
        "id": "sg:person.01241225141.32", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01241225141.32"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "PERFUSE Study Group, Beth Israel Deaconess Medical Center, Cardiovascular Division, Department of Medicine, Harvard Medical School, 185 Pilgrim Road, Farr 319, 02215, Boston, MA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Singh", 
        "givenName": "Priyamvada", 
        "id": "sg:person.01354305747.27", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01354305747.27"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "PERFUSE Study Group, Beth Israel Deaconess Medical Center, Cardiovascular Division, Department of Medicine, Harvard Medical School, 185 Pilgrim Road, Farr 319, 02215, Boston, MA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Halaby", 
        "givenName": "Rim", 
        "id": "sg:person.01355453541.35", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01355453541.35"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "PERFUSE Study Group, Beth Israel Deaconess Medical Center, Cardiovascular Division, Department of Medicine, Harvard Medical School, 185 Pilgrim Road, Farr 319, 02215, Boston, MA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gibson", 
        "givenName": "C. Michael", 
        "id": "sg:person.0750215673.07", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0750215673.07"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1056/nejmoa0706482", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000755110"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/jth.12033", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001359155"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.str.0000199147.30016.74", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008700595"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.str.0000199147.30016.74", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008700595"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(09)60738-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010582076"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa1105819", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010719405"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1538-7836.2007.02799.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012207029"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1538-7836.2007.02799.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012207029"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0735-1097(96)00020-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016273427"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2005-03-1108", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017166487"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.108.832139", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022174377"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(12)61269-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024204479"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(09)60441-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024369135"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.cir.90.1.61", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024985429"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa1112277", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026163141"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.2165/00002018-199921040-00007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027017342", 
          "https://doi.org/10.2165/00002018-199921040-00007"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa050522", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028133368"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/bmj.316.7141.1337", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033767778"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circoutcomes.111.964395", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037073109"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circoutcomes.111.964395", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037073109"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa0904327", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038668813"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(96)09457-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038962422"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa010746", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042739677"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.cir.0000072771.11429.83", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044350994"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/bmj.324.7329.71", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046678775"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm199408253310802", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048330344"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm199105303242206", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048753262"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.7326/0003-4819-143-4-200508160-00005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1073708294"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077369428", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1080009208", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2013-10", 
    "datePublishedReg": "2013-10-01", 
    "description": "In the past two decades there has been a succession of advances in the development of anticoagulant and antiplatelet therapies to be used in the treatment of ACS. Despite optimal dual antiplatelet therapy, nearly 10-12\u00a0% of patients still face a risk of death or myocardial infarction one year following PCI. This large residual risk provides the impetus for the development of more effective strategies. Dual pathway regimens that combine antiplatelets (aspirin and a thienopyridine), along with an anticoagulant such as rivaroxaban may prove to be a therapeutic option in patients with ACS. ", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s11886-013-0411-1", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1021175", 
        "issn": [
          "1523-3782", 
          "1534-3170"
        ], 
        "name": "Current Cardiology Reports", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "10", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "15"
      }
    ], 
    "name": "Is There a Need for \u201cTriple Therapy\u201d? Role of Anticoagulation with Dual Antiplatelet Therapy in Acute Coronary Syndromes (ATLAS Study & TRAP Study)", 
    "pagination": "411", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "c1ee0634ab8a6af95662df0b7dab08253ad0594d4270db2db09f2333d5199acb"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "24022544"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "100888969"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s11886-013-0411-1"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1040710977"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s11886-013-0411-1", 
      "https://app.dimensions.ai/details/publication/pub.1040710977"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T17:34", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8672_00000523.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007%2Fs11886-013-0411-1"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s11886-013-0411-1'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s11886-013-0411-1'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s11886-013-0411-1'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s11886-013-0411-1'


 

This table displays all metadata directly associated to this object as RDF triples.

298 TRIPLES      21 PREDICATES      65 URIs      30 LITERALS      18 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s11886-013-0411-1 schema:about N1aff4279a81945b4a6f17eaf05dd8f2d
2 N23c160e512fa4634aa7169bd98fbaa58
3 N3e61416942bb475387ba0ae0073fb229
4 N7405b804dbd54e3db60aff8a92fe71fe
5 Ncc68107bdbb24da9942459ee90a1e6a2
6 Nd561c91d1c4c477c82a7ed5505b8163a
7 Ne4f7989176704113ac6de63f0f5498ba
8 Nf98225b648eb4a23a6cd6c5118b16f8c
9 Nfaf378bb8e964c42951ac824ae48de02
10 anzsrc-for:11
11 anzsrc-for:1103
12 schema:author Nf19efa3380964414ba04f8b2cbd85acf
13 schema:citation sg:pub.10.2165/00002018-199921040-00007
14 https://app.dimensions.ai/details/publication/pub.1077369428
15 https://app.dimensions.ai/details/publication/pub.1080009208
16 https://doi.org/10.1016/0735-1097(96)00020-4
17 https://doi.org/10.1016/s0140-6736(09)60441-4
18 https://doi.org/10.1016/s0140-6736(09)60738-8
19 https://doi.org/10.1016/s0140-6736(12)61269-0
20 https://doi.org/10.1016/s0140-6736(96)09457-3
21 https://doi.org/10.1056/nejm199105303242206
22 https://doi.org/10.1056/nejm199408253310802
23 https://doi.org/10.1056/nejmoa010746
24 https://doi.org/10.1056/nejmoa050522
25 https://doi.org/10.1056/nejmoa0706482
26 https://doi.org/10.1056/nejmoa0904327
27 https://doi.org/10.1056/nejmoa1105819
28 https://doi.org/10.1056/nejmoa1112277
29 https://doi.org/10.1111/j.1538-7836.2007.02799.x
30 https://doi.org/10.1111/jth.12033
31 https://doi.org/10.1136/bmj.316.7141.1337
32 https://doi.org/10.1136/bmj.324.7329.71
33 https://doi.org/10.1161/01.cir.0000072771.11429.83
34 https://doi.org/10.1161/01.cir.90.1.61
35 https://doi.org/10.1161/01.str.0000199147.30016.74
36 https://doi.org/10.1161/circoutcomes.111.964395
37 https://doi.org/10.1161/circulationaha.108.832139
38 https://doi.org/10.1182/blood-2005-03-1108
39 https://doi.org/10.7326/0003-4819-143-4-200508160-00005
40 schema:datePublished 2013-10
41 schema:datePublishedReg 2013-10-01
42 schema:description In the past two decades there has been a succession of advances in the development of anticoagulant and antiplatelet therapies to be used in the treatment of ACS. Despite optimal dual antiplatelet therapy, nearly 10-12 % of patients still face a risk of death or myocardial infarction one year following PCI. This large residual risk provides the impetus for the development of more effective strategies. Dual pathway regimens that combine antiplatelets (aspirin and a thienopyridine), along with an anticoagulant such as rivaroxaban may prove to be a therapeutic option in patients with ACS.
43 schema:genre research_article
44 schema:inLanguage en
45 schema:isAccessibleForFree false
46 schema:isPartOf N599252da5b3a4fe6a6f5e5c358315cc0
47 N6f517f813afc4cffb19c4bc88a7454ee
48 sg:journal.1021175
49 schema:name Is There a Need for “Triple Therapy”? Role of Anticoagulation with Dual Antiplatelet Therapy in Acute Coronary Syndromes (ATLAS Study & TRAP Study)
50 schema:pagination 411
51 schema:productId N31cf518e390a4dbb83ec2a1a0a37d4b8
52 N898b044c53484cc3a6cdf7890434234e
53 Nb7713e52f01047d3900365d66fa999e4
54 Nda3aa46d36eb4bcab3f30fc23009dd44
55 Nf85071a750a840b18f39b0e7bb08651f
56 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040710977
57 https://doi.org/10.1007/s11886-013-0411-1
58 schema:sdDatePublished 2019-04-10T17:34
59 schema:sdLicense https://scigraph.springernature.com/explorer/license/
60 schema:sdPublisher N18d32fbb66cd4797ace4124cad0a3584
61 schema:url http://link.springer.com/10.1007%2Fs11886-013-0411-1
62 sgo:license sg:explorer/license/
63 sgo:sdDataset articles
64 rdf:type schema:ScholarlyArticle
65 N04ae16c32b5141b59b2e479d8687e4d1 schema:name PERFUSE Study Group, Beth Israel Deaconess Medical Center, Cardiovascular Division, Department of Medicine, Harvard Medical School, 185 Pilgrim Road, Farr 319, 02215, Boston, MA, USA
66 rdf:type schema:Organization
67 N071c3ae1c3844481b53bc45fb354ea95 rdf:first sg:person.0750215673.07
68 rdf:rest rdf:nil
69 N09be550c4a0a4a3f8472eb984869a17b schema:name PERFUSE Study Group, Beth Israel Deaconess Medical Center, Cardiovascular Division, Department of Medicine, Harvard Medical School, 185 Pilgrim Road, Farr 319, 02215, Boston, MA, USA
70 rdf:type schema:Organization
71 N0ccbba0a03414fdd8afff4497f9e20cd rdf:first sg:person.01124776541.50
72 rdf:rest N4c2281b0f7cd41eca13bb122807aa31a
73 N18d32fbb66cd4797ace4124cad0a3584 schema:name Springer Nature - SN SciGraph project
74 rdf:type schema:Organization
75 N1aff4279a81945b4a6f17eaf05dd8f2d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
76 schema:name Randomized Controlled Trials as Topic
77 rdf:type schema:DefinedTerm
78 N1d8e1b24096a4e2ba51efb98bf9a9ad9 schema:name PERFUSE Study Group, Beth Israel Deaconess Medical Center, Cardiovascular Division, Department of Medicine, Harvard Medical School, 185 Pilgrim Road, Farr 319, 02215, Boston, MA, USA
79 rdf:type schema:Organization
80 N23c160e512fa4634aa7169bd98fbaa58 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
81 schema:name Drug Therapy, Combination
82 rdf:type schema:DefinedTerm
83 N25f0d26a58c6470aaa6dfc502972e4b0 schema:name PERFUSE Study Group, Beth Israel Deaconess Medical Center, Cardiovascular Division, Department of Medicine, Harvard Medical School, 185 Pilgrim Road, Farr 319, 02215, Boston, MA, USA
84 rdf:type schema:Organization
85 N2677b87ec5764d91bcf017e2db7179bd rdf:first sg:person.0742434741.28
86 rdf:rest Nf271398b70de4641a76f9426d96ac4e4
87 N31cf518e390a4dbb83ec2a1a0a37d4b8 schema:name nlm_unique_id
88 schema:value 100888969
89 rdf:type schema:PropertyValue
90 N35807811b9ee4430a5c556d0111c6e86 schema:affiliation N09be550c4a0a4a3f8472eb984869a17b
91 schema:familyName Patrick
92 schema:givenName William L.
93 rdf:type schema:Person
94 N3e61416942bb475387ba0ae0073fb229 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
95 schema:name Platelet Aggregation Inhibitors
96 rdf:type schema:DefinedTerm
97 N42b4876fe0f84f4fbe8244d0ce7e103a schema:name PERFUSE Study Group, Beth Israel Deaconess Medical Center, Cardiovascular Division, Department of Medicine, Harvard Medical School, 185 Pilgrim Road, Farr 319, 02215, Boston, MA, USA
98 rdf:type schema:Organization
99 N46d1178239924ab6b5808b490c58597b rdf:first sg:person.01241225141.32
100 rdf:rest Ne33762a9b43b472e9f9a6a5cd3749f63
101 N4c2281b0f7cd41eca13bb122807aa31a rdf:first sg:person.01073026366.33
102 rdf:rest N46d1178239924ab6b5808b490c58597b
103 N599252da5b3a4fe6a6f5e5c358315cc0 schema:issueNumber 10
104 rdf:type schema:PublicationIssue
105 N5b4292fb7a804559bc0229fe48f25ddb schema:name PERFUSE Study Group, Beth Israel Deaconess Medical Center, Cardiovascular Division, Department of Medicine, Harvard Medical School, 185 Pilgrim Road, Farr 319, 02215, Boston, MA, USA
106 rdf:type schema:Organization
107 N6f517f813afc4cffb19c4bc88a7454ee schema:volumeNumber 15
108 rdf:type schema:PublicationVolume
109 N7007170943784ddf8cf42e4cd7042f8b rdf:first sg:person.01056663341.91
110 rdf:rest N0ccbba0a03414fdd8afff4497f9e20cd
111 N712e657a735f4e9e95a35ad133bbc252 schema:affiliation N7cc350644b1a4889a3aee8abbe91f737
112 schema:familyName Patel
113 schema:givenName Charmaine
114 rdf:type schema:Person
115 N7405b804dbd54e3db60aff8a92fe71fe schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
116 schema:name Dose-Response Relationship, Drug
117 rdf:type schema:DefinedTerm
118 N7564a8210be3487ca9694c22c35789e8 rdf:first sg:person.0736166000.49
119 rdf:rest N8bdbb1413cf64c8d95243129cdcdaea8
120 N7cc350644b1a4889a3aee8abbe91f737 schema:name PERFUSE Study Group, Beth Israel Deaconess Medical Center, Cardiovascular Division, Department of Medicine, Harvard Medical School, 185 Pilgrim Road, Farr 319, 02215, Boston, MA, USA
121 rdf:type schema:Organization
122 N898b044c53484cc3a6cdf7890434234e schema:name dimensions_id
123 schema:value pub.1040710977
124 rdf:type schema:PropertyValue
125 N8bdbb1413cf64c8d95243129cdcdaea8 rdf:first sg:person.0626206341.76
126 rdf:rest Nf9a0d3b174824e3eac6c03d4a7db1f0e
127 N93cb7a252ad347459d486d7f7efdb242 schema:name PERFUSE Study Group, Beth Israel Deaconess Medical Center, Cardiovascular Division, Department of Medicine, Harvard Medical School, 185 Pilgrim Road, Farr 319, 02215, Boston, MA, USA
128 rdf:type schema:Organization
129 Na07a6b11d30949f89682445e27d347c8 schema:name PERFUSE Study Group, Beth Israel Deaconess Medical Center, Cardiovascular Division, Department of Medicine, Harvard Medical School, 185 Pilgrim Road, Farr 319, 02215, Boston, MA, USA
130 rdf:type schema:Organization
131 Nb7713e52f01047d3900365d66fa999e4 schema:name readcube_id
132 schema:value c1ee0634ab8a6af95662df0b7dab08253ad0594d4270db2db09f2333d5199acb
133 rdf:type schema:PropertyValue
134 Nbaac79e9504c484097833d950c8ef244 rdf:first sg:person.01355453541.35
135 rdf:rest N071c3ae1c3844481b53bc45fb354ea95
136 Nc052329aa6e14b3ea4f3b723308eb185 schema:affiliation N25f0d26a58c6470aaa6dfc502972e4b0
137 schema:familyName Maddaleni
138 schema:givenName Michael
139 rdf:type schema:Person
140 Ncc68107bdbb24da9942459ee90a1e6a2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
141 schema:name Humans
142 rdf:type schema:DefinedTerm
143 Nd2642870bc724732a305329d3329d83b schema:name PERFUSE Study Group, Beth Israel Deaconess Medical Center, Cardiovascular Division, Department of Medicine, Harvard Medical School, 185 Pilgrim Road, Farr 319, 02215, Boston, MA, USA
144 rdf:type schema:Organization
145 Nd561c91d1c4c477c82a7ed5505b8163a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
146 schema:name Acute Coronary Syndrome
147 rdf:type schema:DefinedTerm
148 Nd593b6255c024dbd9fc8875db8becb83 rdf:first N712e657a735f4e9e95a35ad133bbc252
149 rdf:rest N7564a8210be3487ca9694c22c35789e8
150 Nda3aa46d36eb4bcab3f30fc23009dd44 schema:name pubmed_id
151 schema:value 24022544
152 rdf:type schema:PropertyValue
153 Nda8c9565c36b45959b09ec51f2e1c2be schema:name PERFUSE Study Group, Beth Israel Deaconess Medical Center, Cardiovascular Division, Department of Medicine, Harvard Medical School, 185 Pilgrim Road, Farr 319, 02215, Boston, MA, USA
154 rdf:type schema:Organization
155 Ne33762a9b43b472e9f9a6a5cd3749f63 rdf:first sg:person.01354305747.27
156 rdf:rest Nbaac79e9504c484097833d950c8ef244
157 Ne4dede81fbe3414daf09ba7fec2f5ac0 schema:name PERFUSE Study Group, Beth Israel Deaconess Medical Center, Cardiovascular Division, Department of Medicine, Harvard Medical School, 185 Pilgrim Road, Farr 319, 02215, Boston, MA, USA
158 rdf:type schema:Organization
159 Ne4f7989176704113ac6de63f0f5498ba schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
160 schema:name Blood Coagulation
161 rdf:type schema:DefinedTerm
162 Ne53eeb31bf8c4924acc18c75cc619ce1 schema:name PERFUSE Study Group, Beth Israel Deaconess Medical Center, Cardiovascular Division, Department of Medicine, Harvard Medical School, 185 Pilgrim Road, Farr 319, 02215, Boston, MA, USA
163 rdf:type schema:Organization
164 Nf19efa3380964414ba04f8b2cbd85acf rdf:first N35807811b9ee4430a5c556d0111c6e86
165 rdf:rest Nd593b6255c024dbd9fc8875db8becb83
166 Nf271398b70de4641a76f9426d96ac4e4 rdf:first sg:person.01010550141.55
167 rdf:rest N7007170943784ddf8cf42e4cd7042f8b
168 Nf4bdfcd3ca4d4366a2ca08b0a6d31315 schema:name PERFUSE Study Group, Beth Israel Deaconess Medical Center, Cardiovascular Division, Department of Medicine, Harvard Medical School, 185 Pilgrim Road, Farr 319, 02215, Boston, MA, USA
169 rdf:type schema:Organization
170 Nf85071a750a840b18f39b0e7bb08651f schema:name doi
171 schema:value 10.1007/s11886-013-0411-1
172 rdf:type schema:PropertyValue
173 Nf98225b648eb4a23a6cd6c5118b16f8c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
174 schema:name Clinical Trials, Phase III as Topic
175 rdf:type schema:DefinedTerm
176 Nf9a0d3b174824e3eac6c03d4a7db1f0e rdf:first Nc052329aa6e14b3ea4f3b723308eb185
177 rdf:rest N2677b87ec5764d91bcf017e2db7179bd
178 Nfaf378bb8e964c42951ac824ae48de02 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
179 schema:name Anticoagulants
180 rdf:type schema:DefinedTerm
181 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
182 schema:name Medical and Health Sciences
183 rdf:type schema:DefinedTerm
184 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
185 schema:name Clinical Sciences
186 rdf:type schema:DefinedTerm
187 sg:journal.1021175 schema:issn 1523-3782
188 1534-3170
189 schema:name Current Cardiology Reports
190 rdf:type schema:Periodical
191 sg:person.01010550141.55 schema:affiliation N93cb7a252ad347459d486d7f7efdb242
192 schema:familyName Dolma
193 schema:givenName Kalsang
194 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01010550141.55
195 rdf:type schema:Person
196 sg:person.01056663341.91 schema:affiliation Na07a6b11d30949f89682445e27d347c8
197 schema:familyName Serla
198 schema:givenName Vishnu Vardhan
199 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01056663341.91
200 rdf:type schema:Person
201 sg:person.01073026366.33 schema:affiliation Nda8c9565c36b45959b09ec51f2e1c2be
202 schema:familyName Govindavarjhulla
203 schema:givenName Aditya
204 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01073026366.33
205 rdf:type schema:Person
206 sg:person.01124776541.50 schema:affiliation Nf4bdfcd3ca4d4366a2ca08b0a6d31315
207 schema:familyName Sangha
208 schema:givenName Maheep
209 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01124776541.50
210 rdf:type schema:Person
211 sg:person.01241225141.32 schema:affiliation Ne4dede81fbe3414daf09ba7fec2f5ac0
212 schema:familyName Saddala
213 schema:givenName Prashanth
214 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01241225141.32
215 rdf:type schema:Person
216 sg:person.01354305747.27 schema:affiliation N1d8e1b24096a4e2ba51efb98bf9a9ad9
217 schema:familyName Singh
218 schema:givenName Priyamvada
219 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01354305747.27
220 rdf:type schema:Person
221 sg:person.01355453541.35 schema:affiliation Ne53eeb31bf8c4924acc18c75cc619ce1
222 schema:familyName Halaby
223 schema:givenName Rim
224 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01355453541.35
225 rdf:type schema:Person
226 sg:person.0626206341.76 schema:affiliation N5b4292fb7a804559bc0229fe48f25ddb
227 schema:familyName Narayan
228 schema:givenName Aarti
229 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0626206341.76
230 rdf:type schema:Person
231 sg:person.0736166000.49 schema:affiliation Nd2642870bc724732a305329d3329d83b
232 schema:familyName Guddeti
233 schema:givenName Raviteja
234 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0736166000.49
235 rdf:type schema:Person
236 sg:person.0742434741.28 schema:affiliation N04ae16c32b5141b59b2e479d8687e4d1
237 schema:familyName Kumar
238 schema:givenName Shankar
239 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0742434741.28
240 rdf:type schema:Person
241 sg:person.0750215673.07 schema:affiliation N42b4876fe0f84f4fbe8244d0ce7e103a
242 schema:familyName Gibson
243 schema:givenName C. Michael
244 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0750215673.07
245 rdf:type schema:Person
246 sg:pub.10.2165/00002018-199921040-00007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027017342
247 https://doi.org/10.2165/00002018-199921040-00007
248 rdf:type schema:CreativeWork
249 https://app.dimensions.ai/details/publication/pub.1077369428 schema:CreativeWork
250 https://app.dimensions.ai/details/publication/pub.1080009208 schema:CreativeWork
251 https://doi.org/10.1016/0735-1097(96)00020-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016273427
252 rdf:type schema:CreativeWork
253 https://doi.org/10.1016/s0140-6736(09)60441-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024369135
254 rdf:type schema:CreativeWork
255 https://doi.org/10.1016/s0140-6736(09)60738-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010582076
256 rdf:type schema:CreativeWork
257 https://doi.org/10.1016/s0140-6736(12)61269-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024204479
258 rdf:type schema:CreativeWork
259 https://doi.org/10.1016/s0140-6736(96)09457-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038962422
260 rdf:type schema:CreativeWork
261 https://doi.org/10.1056/nejm199105303242206 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048753262
262 rdf:type schema:CreativeWork
263 https://doi.org/10.1056/nejm199408253310802 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048330344
264 rdf:type schema:CreativeWork
265 https://doi.org/10.1056/nejmoa010746 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042739677
266 rdf:type schema:CreativeWork
267 https://doi.org/10.1056/nejmoa050522 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028133368
268 rdf:type schema:CreativeWork
269 https://doi.org/10.1056/nejmoa0706482 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000755110
270 rdf:type schema:CreativeWork
271 https://doi.org/10.1056/nejmoa0904327 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038668813
272 rdf:type schema:CreativeWork
273 https://doi.org/10.1056/nejmoa1105819 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010719405
274 rdf:type schema:CreativeWork
275 https://doi.org/10.1056/nejmoa1112277 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026163141
276 rdf:type schema:CreativeWork
277 https://doi.org/10.1111/j.1538-7836.2007.02799.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1012207029
278 rdf:type schema:CreativeWork
279 https://doi.org/10.1111/jth.12033 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001359155
280 rdf:type schema:CreativeWork
281 https://doi.org/10.1136/bmj.316.7141.1337 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033767778
282 rdf:type schema:CreativeWork
283 https://doi.org/10.1136/bmj.324.7329.71 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046678775
284 rdf:type schema:CreativeWork
285 https://doi.org/10.1161/01.cir.0000072771.11429.83 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044350994
286 rdf:type schema:CreativeWork
287 https://doi.org/10.1161/01.cir.90.1.61 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024985429
288 rdf:type schema:CreativeWork
289 https://doi.org/10.1161/01.str.0000199147.30016.74 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008700595
290 rdf:type schema:CreativeWork
291 https://doi.org/10.1161/circoutcomes.111.964395 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037073109
292 rdf:type schema:CreativeWork
293 https://doi.org/10.1161/circulationaha.108.832139 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022174377
294 rdf:type schema:CreativeWork
295 https://doi.org/10.1182/blood-2005-03-1108 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017166487
296 rdf:type schema:CreativeWork
297 https://doi.org/10.7326/0003-4819-143-4-200508160-00005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1073708294
298 rdf:type schema:CreativeWork
 




Preview window. Press ESC to close (or click here)


...