The Multidisciplinary Management of Osteosarcoma View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2009-02-24

AUTHORS

Noah Federman, Nicholas Bernthal, Fritz C. Eilber, William D. Tap

ABSTRACT

Opinion statementPatients with suspected or confirmed osteosarcoma should be evaluated and treated at a comprehensive cancer center within a multidisciplinary sarcoma program that includes pediatric, medical and radiation oncologists, orthopedic and surgical oncologists, musculoskeletal pathologists, and radiologists. Successful treatment involves proper diagnosis, neoadjuvant and adjuvant multi-agent chemotherapy, and aggressive surgery with an emphasis toward limb-preserving procedures. Treatment of osteosarcoma should be undertaken within the framework of large cooperative group clinical trials for children, adolescents, and adults. Patients treated with osteosarcoma should be followed closely both for recurrence of disease and for development of late effects of the treatment of their cancer. The treatment of metastatic, recurrent and/or refractory disease is more controversial. Despite advances in systemic treatment, surgical technique, and supportive care, the overall outcome is still poor. More... »

PAGES

82-93

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11864-009-0087-3

DOI

http://dx.doi.org/10.1007/s11864-009-0087-3

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1012746388

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/19238553


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