Polypropylene mesh and systemic side effects in inguinal hernia repair: current evidence View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-03-27

AUTHORS

Cillian Clancy, Patrick Jordan, Paul F. Ridgway

ABSTRACT

INTRODUCTION: Increasing awareness and regulatory body attention is directed towards the insertion of synthetic material for a variety of surgical procedures. This review aims to assess current evidence regarding systemic and auto-immune effects of polypropylene mesh insertion in hernia repair. METHODS: The electronic literature on systemic and auto-immune effects associated with mesh insertion was examined. RESULTS: Foreign body reaction following mesh implantation initiates an acute inflammatory cellular response. Involved markers such as IL-1, IL-6, IL-10 and fibrinogen are increased in circulation in the presence of mesh but return to normal at 7 days post operatively. Oxidative degradation of implanted mesh is likely, but no evidence exists to support systemic absorption or resulting disease effects. Variable cytokine production in healthy hosts leading to unpredictable or overwhelming response to implanted biomaterial warrants further investigation. Clinical studies show no associated long-term systemic effects with mesh. CONCLUSION: To date, there remains no evidence to link polypropylene mesh and systemic or auto-immune symptoms. Based on current evidence, the use of polypropylene mesh is supported. More... »

PAGES

1-8

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11845-019-02008-5

DOI

http://dx.doi.org/10.1007/s11845-019-02008-5

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1113005800

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30915679


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Trinity College Dublin", 
          "id": "https://www.grid.ac/institutes/grid.8217.c", 
          "name": [
            "Department of Surgery, Tallaght University Hospital, Dublin, Ireland", 
            "Department of Surgery, Trinity College Dublin, Dublin, Ireland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Clancy", 
        "givenName": "Cillian", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Trinity College Dublin", 
          "id": "https://www.grid.ac/institutes/grid.8217.c", 
          "name": [
            "Department of Surgery, Tallaght University Hospital, Dublin, Ireland", 
            "Department of Surgery, Trinity College Dublin, Dublin, Ireland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Jordan", 
        "givenName": "Patrick", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Trinity College Dublin", 
          "id": "https://www.grid.ac/institutes/grid.8217.c", 
          "name": [
            "Department of Surgery, Tallaght University Hospital, Dublin, Ireland", 
            "Department of Surgery, Trinity College Dublin, Dublin, Ireland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ridgway", 
        "givenName": "Paul F.", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/j.biomaterials.2015.09.015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000182918"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10029-007-0277-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003884485", 
          "https://doi.org/10.1007/s10029-007-0277-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10029-007-0277-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003884485", 
          "https://doi.org/10.1007/s10029-007-0277-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ijscr.2016.07.042", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006332968"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000658-200203000-00003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006643122"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000658-200203000-00003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006643122"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jbm.820100611", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006984411"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/aog.0b013e3181f39b20", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008680136"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/aog.0b013e3181f39b20", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008680136"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/ije/dyq164", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011439220"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00192-009-1021-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012191861", 
          "https://doi.org/10.1007/s00192-009-1021-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00192-009-1021-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012191861", 
          "https://doi.org/10.1007/s00192-009-1021-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1155/2015/583570", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014409467"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jbm.b.30764", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016344560"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0142-9612(00)00089-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018608054"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ijc.23932", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020089242"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1258/shorts.2010.010071", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020147967"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/cyto.1996.0155", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021763136"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1072-7515(01)00941-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021843507"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00192-016-3131-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026791592", 
          "https://doi.org/10.1007/s00192-016-3131-4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00192-016-3131-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026791592", 
          "https://doi.org/10.1007/s00192-016-3131-4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ajog.2016.12.021", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026823605"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/11024159950189726", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028335887"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10029-009-0529-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029229807", 
          "https://doi.org/10.1007/s10029-009-0529-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10029-009-0529-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029229807", 
          "https://doi.org/10.1007/s10029-009-0529-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0002-9610(00)00445-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032333966"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/84209", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034992744", 
          "https://doi.org/10.1038/84209"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/84209", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034992744", 
          "https://doi.org/10.1038/84209"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10029-012-0928-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035397218", 
          "https://doi.org/10.1007/s10029-012-0928-z"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10029-011-0798-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035502122", 
          "https://doi.org/10.1007/s10029-011-0798-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jbm.b.33502", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035712984"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s001040050007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038248241", 
          "https://doi.org/10.1007/s001040050007"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1515/cclm.2000.040", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039599006"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00268-005-7967-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039981259", 
          "https://doi.org/10.1007/s00268-005-7967-x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00268-005-7967-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039981259", 
          "https://doi.org/10.1007/s00268-005-7967-x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.smim.2007.11.004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041601862"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00024382-200014030-00011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044525266"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00024382-200014030-00011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044525266"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jhsa.2015.03.004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047326410"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/14651858.cd001543.pub4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049014619"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/bjs.4023", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051008112"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/110241599750007504", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052199487"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/mcc.0000000000000213", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053713722"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/mcc.0000000000000213", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053713722"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4240/wjgs.v7.i10.226", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1072397994"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082832940", 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10029-017-1591-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083862462", 
          "https://doi.org/10.1007/s10029-017-1591-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10029-017-1591-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083862462", 
          "https://doi.org/10.1007/s10029-017-1591-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/1553350617697849", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084247554"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/1553350617697849", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084247554"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-1-84882-136-1_25", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1089622324", 
          "https://doi.org/10.1007/978-1-84882-136-1_25"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-1-84882-136-1_25", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1089622324", 
          "https://doi.org/10.1007/978-1-84882-136-1_25"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3390/membranes7030047", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1091286413"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00423-017-1618-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1091308686", 
          "https://doi.org/10.1007/s00423-017-1618-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/prs.0000000000003711", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1091979885"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/prs.0000000000003711", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1091979885"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/prs.0000000000003711", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1091979885"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jamcollsurg.2017.10.020", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1092636970"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10029-018-1734-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1100551692", 
          "https://doi.org/10.1007/s10029-018-1734-z"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10029-018-1734-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1100551692", 
          "https://doi.org/10.1007/s10029-018-1734-z"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.surg.2017.12.017", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1101409709"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2019-03-27", 
    "datePublishedReg": "2019-03-27", 
    "description": "INTRODUCTION: Increasing awareness and regulatory body attention is directed towards the insertion of synthetic material for a variety of surgical procedures. This review aims to assess current evidence regarding systemic and auto-immune effects of polypropylene mesh insertion in hernia repair.\nMETHODS: The electronic literature on systemic and auto-immune effects associated with mesh insertion was examined.\nRESULTS: Foreign body reaction following mesh implantation initiates an acute inflammatory cellular response. Involved markers such as IL-1, IL-6, IL-10 and fibrinogen are increased in circulation in the presence of mesh but return to normal at 7\u00a0days post operatively. Oxidative degradation of implanted mesh is likely, but no evidence exists to support systemic absorption or resulting disease effects. Variable cytokine production in healthy hosts leading to unpredictable or overwhelming response to implanted biomaterial warrants further investigation. Clinical studies show no associated long-term systemic effects with mesh.\nCONCLUSION: To date, there remains no evidence to link polypropylene mesh and systemic or auto-immune symptoms. Based on current evidence, the use of polypropylene mesh is supported.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s11845-019-02008-5", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1037510", 
        "issn": [
          "0021-1265", 
          "1863-4362"
        ], 
        "name": "Irish Journal of Medical Science", 
        "type": "Periodical"
      }
    ], 
    "name": "Polypropylene mesh and systemic side effects in inguinal hernia repair: current evidence", 
    "pagination": "1-8", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "47e5bb34fefc945409cffdaa5f9e84b560bc96de74aded7c900e0772451b301f"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30915679"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "7806864"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s11845-019-02008-5"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1113005800"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s11845-019-02008-5", 
      "https://app.dimensions.ai/details/publication/pub.1113005800"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T13:12", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000367_0000000367/records_88255_00000001.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1007%2Fs11845-019-02008-5"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s11845-019-02008-5'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s11845-019-02008-5'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s11845-019-02008-5'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s11845-019-02008-5'


 

This table displays all metadata directly associated to this object as RDF triples.

222 TRIPLES      21 PREDICATES      71 URIs      18 LITERALS      7 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s11845-019-02008-5 schema:about anzsrc-for:11
2 anzsrc-for:1103
3 schema:author Nda78fa0bdcde41089db121aa2df20819
4 schema:citation sg:pub.10.1007/978-1-84882-136-1_25
5 sg:pub.10.1007/s001040050007
6 sg:pub.10.1007/s00192-009-1021-8
7 sg:pub.10.1007/s00192-016-3131-4
8 sg:pub.10.1007/s00268-005-7967-x
9 sg:pub.10.1007/s00423-017-1618-1
10 sg:pub.10.1007/s10029-007-0277-5
11 sg:pub.10.1007/s10029-009-0529-7
12 sg:pub.10.1007/s10029-011-0798-9
13 sg:pub.10.1007/s10029-012-0928-z
14 sg:pub.10.1007/s10029-017-1591-1
15 sg:pub.10.1007/s10029-018-1734-z
16 sg:pub.10.1038/84209
17 https://app.dimensions.ai/details/publication/pub.1082832940
18 https://doi.org/10.1002/14651858.cd001543.pub4
19 https://doi.org/10.1002/bjs.4023
20 https://doi.org/10.1002/ijc.23932
21 https://doi.org/10.1002/jbm.820100611
22 https://doi.org/10.1002/jbm.b.30764
23 https://doi.org/10.1002/jbm.b.33502
24 https://doi.org/10.1006/cyto.1996.0155
25 https://doi.org/10.1016/j.ajog.2016.12.021
26 https://doi.org/10.1016/j.biomaterials.2015.09.015
27 https://doi.org/10.1016/j.ijscr.2016.07.042
28 https://doi.org/10.1016/j.jamcollsurg.2017.10.020
29 https://doi.org/10.1016/j.jhsa.2015.03.004
30 https://doi.org/10.1016/j.smim.2007.11.004
31 https://doi.org/10.1016/j.surg.2017.12.017
32 https://doi.org/10.1016/s0002-9610(00)00445-1
33 https://doi.org/10.1016/s0142-9612(00)00089-2
34 https://doi.org/10.1016/s1072-7515(01)00941-3
35 https://doi.org/10.1080/11024159950189726
36 https://doi.org/10.1080/110241599750007504
37 https://doi.org/10.1093/ije/dyq164
38 https://doi.org/10.1097/00000658-200203000-00003
39 https://doi.org/10.1097/00024382-200014030-00011
40 https://doi.org/10.1097/aog.0b013e3181f39b20
41 https://doi.org/10.1097/mcc.0000000000000213
42 https://doi.org/10.1097/prs.0000000000003711
43 https://doi.org/10.1155/2015/583570
44 https://doi.org/10.1177/1553350617697849
45 https://doi.org/10.1258/shorts.2010.010071
46 https://doi.org/10.1515/cclm.2000.040
47 https://doi.org/10.3390/membranes7030047
48 https://doi.org/10.4240/wjgs.v7.i10.226
49 schema:datePublished 2019-03-27
50 schema:datePublishedReg 2019-03-27
51 schema:description INTRODUCTION: Increasing awareness and regulatory body attention is directed towards the insertion of synthetic material for a variety of surgical procedures. This review aims to assess current evidence regarding systemic and auto-immune effects of polypropylene mesh insertion in hernia repair. METHODS: The electronic literature on systemic and auto-immune effects associated with mesh insertion was examined. RESULTS: Foreign body reaction following mesh implantation initiates an acute inflammatory cellular response. Involved markers such as IL-1, IL-6, IL-10 and fibrinogen are increased in circulation in the presence of mesh but return to normal at 7 days post operatively. Oxidative degradation of implanted mesh is likely, but no evidence exists to support systemic absorption or resulting disease effects. Variable cytokine production in healthy hosts leading to unpredictable or overwhelming response to implanted biomaterial warrants further investigation. Clinical studies show no associated long-term systemic effects with mesh. CONCLUSION: To date, there remains no evidence to link polypropylene mesh and systemic or auto-immune symptoms. Based on current evidence, the use of polypropylene mesh is supported.
52 schema:genre research_article
53 schema:inLanguage en
54 schema:isAccessibleForFree false
55 schema:isPartOf sg:journal.1037510
56 schema:name Polypropylene mesh and systemic side effects in inguinal hernia repair: current evidence
57 schema:pagination 1-8
58 schema:productId N5f311c0e220a4468a375b64dbe472c4a
59 N609117c76da54830b52aa3aff539d878
60 N84a634d0928a482283ec30c739467227
61 Ncc6fb54f58444989bbe37fa3fbe3192f
62 Nd57cc7af3088482fa2a403ad75c10304
63 schema:sameAs https://app.dimensions.ai/details/publication/pub.1113005800
64 https://doi.org/10.1007/s11845-019-02008-5
65 schema:sdDatePublished 2019-04-11T13:12
66 schema:sdLicense https://scigraph.springernature.com/explorer/license/
67 schema:sdPublisher N905d09cf70a845dfbc1e533f91c2dcb6
68 schema:url https://link.springer.com/10.1007%2Fs11845-019-02008-5
69 sgo:license sg:explorer/license/
70 sgo:sdDataset articles
71 rdf:type schema:ScholarlyArticle
72 N1743414d5daa498dbc6fbdc184fd5e24 schema:affiliation https://www.grid.ac/institutes/grid.8217.c
73 schema:familyName Jordan
74 schema:givenName Patrick
75 rdf:type schema:Person
76 N5f311c0e220a4468a375b64dbe472c4a schema:name readcube_id
77 schema:value 47e5bb34fefc945409cffdaa5f9e84b560bc96de74aded7c900e0772451b301f
78 rdf:type schema:PropertyValue
79 N609117c76da54830b52aa3aff539d878 schema:name doi
80 schema:value 10.1007/s11845-019-02008-5
81 rdf:type schema:PropertyValue
82 N6d3f3a2f3d6944fda80f17c4cdef4394 rdf:first N1743414d5daa498dbc6fbdc184fd5e24
83 rdf:rest Nee774e64935e4c58a5fcaec397fd7472
84 N6f710f9d00924c3e973d0a58a9232403 schema:affiliation https://www.grid.ac/institutes/grid.8217.c
85 schema:familyName Ridgway
86 schema:givenName Paul F.
87 rdf:type schema:Person
88 N84a634d0928a482283ec30c739467227 schema:name pubmed_id
89 schema:value 30915679
90 rdf:type schema:PropertyValue
91 N85b5d2129a58477fbf5f68b4996ca95f schema:affiliation https://www.grid.ac/institutes/grid.8217.c
92 schema:familyName Clancy
93 schema:givenName Cillian
94 rdf:type schema:Person
95 N905d09cf70a845dfbc1e533f91c2dcb6 schema:name Springer Nature - SN SciGraph project
96 rdf:type schema:Organization
97 Ncc6fb54f58444989bbe37fa3fbe3192f schema:name nlm_unique_id
98 schema:value 7806864
99 rdf:type schema:PropertyValue
100 Nd57cc7af3088482fa2a403ad75c10304 schema:name dimensions_id
101 schema:value pub.1113005800
102 rdf:type schema:PropertyValue
103 Nda78fa0bdcde41089db121aa2df20819 rdf:first N85b5d2129a58477fbf5f68b4996ca95f
104 rdf:rest N6d3f3a2f3d6944fda80f17c4cdef4394
105 Nee774e64935e4c58a5fcaec397fd7472 rdf:first N6f710f9d00924c3e973d0a58a9232403
106 rdf:rest rdf:nil
107 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
108 schema:name Medical and Health Sciences
109 rdf:type schema:DefinedTerm
110 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
111 schema:name Clinical Sciences
112 rdf:type schema:DefinedTerm
113 sg:journal.1037510 schema:issn 0021-1265
114 1863-4362
115 schema:name Irish Journal of Medical Science
116 rdf:type schema:Periodical
117 sg:pub.10.1007/978-1-84882-136-1_25 schema:sameAs https://app.dimensions.ai/details/publication/pub.1089622324
118 https://doi.org/10.1007/978-1-84882-136-1_25
119 rdf:type schema:CreativeWork
120 sg:pub.10.1007/s001040050007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038248241
121 https://doi.org/10.1007/s001040050007
122 rdf:type schema:CreativeWork
123 sg:pub.10.1007/s00192-009-1021-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012191861
124 https://doi.org/10.1007/s00192-009-1021-8
125 rdf:type schema:CreativeWork
126 sg:pub.10.1007/s00192-016-3131-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026791592
127 https://doi.org/10.1007/s00192-016-3131-4
128 rdf:type schema:CreativeWork
129 sg:pub.10.1007/s00268-005-7967-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1039981259
130 https://doi.org/10.1007/s00268-005-7967-x
131 rdf:type schema:CreativeWork
132 sg:pub.10.1007/s00423-017-1618-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1091308686
133 https://doi.org/10.1007/s00423-017-1618-1
134 rdf:type schema:CreativeWork
135 sg:pub.10.1007/s10029-007-0277-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003884485
136 https://doi.org/10.1007/s10029-007-0277-5
137 rdf:type schema:CreativeWork
138 sg:pub.10.1007/s10029-009-0529-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029229807
139 https://doi.org/10.1007/s10029-009-0529-7
140 rdf:type schema:CreativeWork
141 sg:pub.10.1007/s10029-011-0798-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035502122
142 https://doi.org/10.1007/s10029-011-0798-9
143 rdf:type schema:CreativeWork
144 sg:pub.10.1007/s10029-012-0928-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1035397218
145 https://doi.org/10.1007/s10029-012-0928-z
146 rdf:type schema:CreativeWork
147 sg:pub.10.1007/s10029-017-1591-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083862462
148 https://doi.org/10.1007/s10029-017-1591-1
149 rdf:type schema:CreativeWork
150 sg:pub.10.1007/s10029-018-1734-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1100551692
151 https://doi.org/10.1007/s10029-018-1734-z
152 rdf:type schema:CreativeWork
153 sg:pub.10.1038/84209 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034992744
154 https://doi.org/10.1038/84209
155 rdf:type schema:CreativeWork
156 https://app.dimensions.ai/details/publication/pub.1082832940 schema:CreativeWork
157 https://doi.org/10.1002/14651858.cd001543.pub4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049014619
158 rdf:type schema:CreativeWork
159 https://doi.org/10.1002/bjs.4023 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051008112
160 rdf:type schema:CreativeWork
161 https://doi.org/10.1002/ijc.23932 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020089242
162 rdf:type schema:CreativeWork
163 https://doi.org/10.1002/jbm.820100611 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006984411
164 rdf:type schema:CreativeWork
165 https://doi.org/10.1002/jbm.b.30764 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016344560
166 rdf:type schema:CreativeWork
167 https://doi.org/10.1002/jbm.b.33502 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035712984
168 rdf:type schema:CreativeWork
169 https://doi.org/10.1006/cyto.1996.0155 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021763136
170 rdf:type schema:CreativeWork
171 https://doi.org/10.1016/j.ajog.2016.12.021 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026823605
172 rdf:type schema:CreativeWork
173 https://doi.org/10.1016/j.biomaterials.2015.09.015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000182918
174 rdf:type schema:CreativeWork
175 https://doi.org/10.1016/j.ijscr.2016.07.042 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006332968
176 rdf:type schema:CreativeWork
177 https://doi.org/10.1016/j.jamcollsurg.2017.10.020 schema:sameAs https://app.dimensions.ai/details/publication/pub.1092636970
178 rdf:type schema:CreativeWork
179 https://doi.org/10.1016/j.jhsa.2015.03.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047326410
180 rdf:type schema:CreativeWork
181 https://doi.org/10.1016/j.smim.2007.11.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041601862
182 rdf:type schema:CreativeWork
183 https://doi.org/10.1016/j.surg.2017.12.017 schema:sameAs https://app.dimensions.ai/details/publication/pub.1101409709
184 rdf:type schema:CreativeWork
185 https://doi.org/10.1016/s0002-9610(00)00445-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032333966
186 rdf:type schema:CreativeWork
187 https://doi.org/10.1016/s0142-9612(00)00089-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018608054
188 rdf:type schema:CreativeWork
189 https://doi.org/10.1016/s1072-7515(01)00941-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021843507
190 rdf:type schema:CreativeWork
191 https://doi.org/10.1080/11024159950189726 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028335887
192 rdf:type schema:CreativeWork
193 https://doi.org/10.1080/110241599750007504 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052199487
194 rdf:type schema:CreativeWork
195 https://doi.org/10.1093/ije/dyq164 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011439220
196 rdf:type schema:CreativeWork
197 https://doi.org/10.1097/00000658-200203000-00003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006643122
198 rdf:type schema:CreativeWork
199 https://doi.org/10.1097/00024382-200014030-00011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044525266
200 rdf:type schema:CreativeWork
201 https://doi.org/10.1097/aog.0b013e3181f39b20 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008680136
202 rdf:type schema:CreativeWork
203 https://doi.org/10.1097/mcc.0000000000000213 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053713722
204 rdf:type schema:CreativeWork
205 https://doi.org/10.1097/prs.0000000000003711 schema:sameAs https://app.dimensions.ai/details/publication/pub.1091979885
206 rdf:type schema:CreativeWork
207 https://doi.org/10.1155/2015/583570 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014409467
208 rdf:type schema:CreativeWork
209 https://doi.org/10.1177/1553350617697849 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084247554
210 rdf:type schema:CreativeWork
211 https://doi.org/10.1258/shorts.2010.010071 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020147967
212 rdf:type schema:CreativeWork
213 https://doi.org/10.1515/cclm.2000.040 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039599006
214 rdf:type schema:CreativeWork
215 https://doi.org/10.3390/membranes7030047 schema:sameAs https://app.dimensions.ai/details/publication/pub.1091286413
216 rdf:type schema:CreativeWork
217 https://doi.org/10.4240/wjgs.v7.i10.226 schema:sameAs https://app.dimensions.ai/details/publication/pub.1072397994
218 rdf:type schema:CreativeWork
219 https://www.grid.ac/institutes/grid.8217.c schema:alternateName Trinity College Dublin
220 schema:name Department of Surgery, Tallaght University Hospital, Dublin, Ireland
221 Department of Surgery, Trinity College Dublin, Dublin, Ireland
222 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...