Dépression et cancer : le mythe à l’épreuve de l’épidémiologie View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2010-03

AUTHORS

C. Lemogne, S.-M. Consoli

ABSTRACT

Trois méta-analyses récentes, portant sur de larges études prospectives, concluent à une association faiblement significative entre dépression, notamment chronique, et développement d’un cancer. Cette association concerne aussi bien l’incidence du cancer chez des sujets a priori sains que la mortalité en cas de cancer déclaré. Dans les deux cas, l’association est statistiquement significative, mais la significativité clinique, mesurée par la taille de l’effet, est faible. Les mécanismes expliquant ces associations impliquent probablement certains facteurs confondants, c’est-à-dire augmentant à la fois le risque de dépression et de cancer (ou péjorant son pronostic) sans lien direct entre les deux, ainsi que des médiateurs comportementaux et biologiques, c’est-à-dire des corrélats de la dépression ayant une influence péjorative secondaire sur le risque ou le pronostic du cancer. D’autres études sont nécessaires pour préciser les implications cliniques de ces associations. More... »

PAGES

22-27

Journal

TITLE

Psycho-Oncologie

ISSUE

1

VOLUME

4

Author Affiliations

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11839-010-0242-x

DOI

http://dx.doi.org/10.1007/s11839-010-0242-x

DIMENSIONS

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