Lactate determination in pleural and abdominal effusions: a quick diagnostic marker of exudate—a pilot study View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2018-09

AUTHORS

Giovanni Porta, Fabio G. Numis, Valerio Rosato, Antonio Pagano, Mario Masarone, Giorgio Bosso, Claudia Serra, Luca Rinaldi, Maria C. Fascione, Annalisa Amelia, Fiorella Paladino, Fernando Schiraldi

ABSTRACT

Pleural or abdominal effusions are frequent findings in ICU and Internal Medicine patients. Diagnostic gold standard to distinguish between transudate and exudate is represented by "Light's Criteria," but, unfortunately, the chemical-physical examination for their calculation is not a rapid test. Pursuing an acid-base assessment of the fluid by a blood-gas analyzer, an increase of lactate beyond the normal serum range is reported in the exudative effusions. The advantages of this test are that it is a very fast bed-side test, executable directly by the physician. The aim of this study is to evaluate whether the increase in lactate in pleural and abdominal effusions might be used as a criterion for the differential diagnosis of the nature of the fluid. Sixty-nine patients with pleural or abdominal effusions and clinical indication for thoracentesis or paracentesis were enrolled. Acid-base assessment with lactate, total protein, and LDH dosage on the serum, and acid-base assessment with lactate, total protein, and LDH dosage, cytology, and bacterial culture on the fluid were performed to each patient. Fluid-blood lactate difference (ΔLacFB) and fluid-blood lactate ratio (LacFB ratio) were calculated. A statistical analysis was carried out for fluid lactate (LacF), ΔLacFB, and LacFB ratio, performing ROC curves to find the cut-off values with best sensitivity (Sn) and specificity (Sp) predicting an exudate diagnosis: LacF: cut-off value: 2.4 mmol/L; AU-ROC 0.854 95% CI 0.756-0.952; Sn 0.77; Sp 0.84. ΔLacFB: cut-off value: 0.95 mmol/L; Au-ROC 0.876 95% CI 0.785-0.966; Sn 0.80; Sp 0.92. LacFB ratio: cut-off value: 2 mmol/L; Au-ROC 0.730 95% CI 0.609-0.851; Sn 0.74; Sp 0.65. Lactate dosage by blood-gas analyzer on pleural and abdominal effusions seems to be a promising tool to predict a diagnosis of exudate. More... »

PAGES

901-906

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11739-017-1757-y

DOI

http://dx.doi.org/10.1007/s11739-017-1757-y

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1092002795

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/28965174


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Ospedale Antonio Cardarelli", 
          "id": "https://www.grid.ac/institutes/grid.413172.2", 
          "name": [
            "Emergency Department, \u201cA. Cardarelli\u201d Hospital, Via Cardarelli 9, 80131, Naples, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Porta", 
        "givenName": "Giovanni", 
        "id": "sg:person.0744267626.57", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0744267626.57"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Emergency Department, \u201cSan Paolo\u201d Hospital, Naples, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Numis", 
        "givenName": "Fabio G.", 
        "id": "sg:person.016613064424.21", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016613064424.21"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Second University of Naples", 
          "id": "https://www.grid.ac/institutes/grid.9841.4", 
          "name": [
            "Internal Medicine and Hepatology Department, Second University of Naples, Naples, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rosato", 
        "givenName": "Valerio", 
        "id": "sg:person.01342415642.47", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01342415642.47"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Ospedale Antonio Cardarelli", 
          "id": "https://www.grid.ac/institutes/grid.413172.2", 
          "name": [
            "Emergency Department, \u201cA. Cardarelli\u201d Hospital, Via Cardarelli 9, 80131, Naples, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pagano", 
        "givenName": "Antonio", 
        "id": "sg:person.0701071407.40", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0701071407.40"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Salerno", 
          "id": "https://www.grid.ac/institutes/grid.11780.3f", 
          "name": [
            "Internal Medicine and Hepatology Unit, University of Salerno, Baronissi, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Masarone", 
        "givenName": "Mario", 
        "id": "sg:person.047374530.79", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.047374530.79"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Ospedale Antonio Cardarelli", 
          "id": "https://www.grid.ac/institutes/grid.413172.2", 
          "name": [
            "Emergency Department, \u201cA. Cardarelli\u201d Hospital, Via Cardarelli 9, 80131, Naples, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bosso", 
        "givenName": "Giorgio", 
        "id": "sg:person.011350513023.14", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011350513023.14"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Ospedale Antonio Cardarelli", 
          "id": "https://www.grid.ac/institutes/grid.413172.2", 
          "name": [
            "Emergency Department, \u201cA. Cardarelli\u201d Hospital, Via Cardarelli 9, 80131, Naples, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Serra", 
        "givenName": "Claudia", 
        "id": "sg:person.015441712043.98", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015441712043.98"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Second University of Naples", 
          "id": "https://www.grid.ac/institutes/grid.9841.4", 
          "name": [
            "Internal Medicine and Hepatology Department, Second University of Naples, Naples, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rinaldi", 
        "givenName": "Luca", 
        "id": "sg:person.0707665661.15", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0707665661.15"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Second University of Naples", 
          "id": "https://www.grid.ac/institutes/grid.9841.4", 
          "name": [
            "Internal Medicine and Hepatology Department, Second University of Naples, Naples, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fascione", 
        "givenName": "Maria C.", 
        "id": "sg:person.0724642714.36", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0724642714.36"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Second University of Naples", 
          "id": "https://www.grid.ac/institutes/grid.9841.4", 
          "name": [
            "Internal Medicine and Hepatology Department, Second University of Naples, Naples, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Amelia", 
        "givenName": "Annalisa", 
        "id": "sg:person.011777676161.16", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011777676161.16"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Ospedale Antonio Cardarelli", 
          "id": "https://www.grid.ac/institutes/grid.413172.2", 
          "name": [
            "Emergency Department, \u201cA. Cardarelli\u201d Hospital, Via Cardarelli 9, 80131, Naples, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Paladino", 
        "givenName": "Fiorella", 
        "id": "sg:person.01274324107.13", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01274324107.13"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Emergency Department, \u201cSan Paolo\u201d Hospital, Naples, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Schiraldi", 
        "givenName": "Fernando", 
        "id": "sg:person.01123750475.74", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01123750475.74"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1097/00005768-200004000-00011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002035239"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00005768-200004000-00011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002035239"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1172/jci110647", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003994047"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01645433", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004071461", 
          "https://doi.org/10.1007/bf01645433"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01645433", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004071461", 
          "https://doi.org/10.1007/bf01645433"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/shk.0b013e318167378f", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004099275"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/shk.0b013e318167378f", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004099275"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/shk.0b013e318167378f", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004099275"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1699-0463.1984.tb02799.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006410938"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1699-0463.1984.tb02799.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006410938"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/hep.1840010310", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007949479"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0736-4679(84)90005-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007998919"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00024382-200014010-00002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008420682"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00024382-200014010-00002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008420682"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jama.1973.03220300019004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012388812"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/ccm.0b013e31827e83af", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014463755"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/ccm.0b013e31827e83af", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014463755"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/pcc.0b013e3182196aa2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016428633"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/pcc.0b013e3182196aa2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016428633"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1164/ajrccm/139.3.663", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016902211"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000194303", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017272538"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/thx.58.suppl_2.ii8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021024807"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/thx.58.suppl_2.ii8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021024807"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/00365540110076732", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021625024"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/cc1509", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022962194", 
          "https://doi.org/10.1186/cc1509"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/archinte.1973.03650120060011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023198977"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nchembio.971", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024041597", 
          "https://doi.org/10.1038/nchembio.971"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0002-9343(84)90542-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025405416"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/archinte.1970.00310080075009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026079198"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1378/chest.92.2.296", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027084093"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1378/chest.70.3.328", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030301493"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmcp010731", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032329691"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000194067", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033392266"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02013087", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035761786", 
          "https://doi.org/10.1007/bf02013087"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02013087", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035761786", 
          "https://doi.org/10.1007/bf02013087"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1183/09031936.00.15116600", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037176466"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0016-5085(90)91300-u", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039027283"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/hep.1840040316", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040617752"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3109/00365548809117222", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040683049"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/1097-0142(196003/04)13:2<283::aid-cncr2820130212>3.0.co;2-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041517071"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1113/jphysiol.2009.178350", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042721678"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s12879-016-1818-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045931266", 
          "https://doi.org/10.1186/s12879-016-1818-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s12879-016-1818-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045931266", 
          "https://doi.org/10.1186/s12879-016-1818-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000194802", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046693191"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmra1309483", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048905821"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1164/arrd.1978.117.4.665", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049245797"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1378/chest.15-1703", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049375781"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000196392", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053668512"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/archinte.132.6.854", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1054106371"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/clinids/3.3.470", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059474567"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.7326/0003-4819-110-7-567", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1073693858"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.7326/0003-4819-76-6-985", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1073730041"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.7326/0003-4819-77-4-507", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1073730288"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075055698", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1076831901", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078158550", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078763664", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079032077", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079266830", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0749-0704(18)30516-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1079690558"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079878470", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081999592", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2018-09", 
    "datePublishedReg": "2018-09-01", 
    "description": "Pleural or abdominal effusions are frequent findings in ICU and Internal Medicine patients. Diagnostic gold standard to distinguish between transudate and exudate is represented by \"Light's Criteria,\" but, unfortunately, the chemical-physical examination for their calculation is not a rapid test. Pursuing an acid-base assessment of the fluid by a blood-gas analyzer, an increase of lactate beyond the normal serum range is reported in the exudative effusions. The advantages of this test are that it is a very fast bed-side test, executable directly by the physician. The aim of this study is to evaluate whether the increase in lactate in pleural and abdominal effusions might be used as a criterion for the differential diagnosis of the nature of the fluid. Sixty-nine patients with pleural or abdominal effusions and clinical indication for thoracentesis or paracentesis were enrolled. Acid-base assessment with lactate, total protein, and LDH dosage on the serum, and acid-base assessment with lactate, total protein, and LDH dosage, cytology, and bacterial culture on the fluid were performed to each patient. Fluid-blood lactate difference (\u0394LacFB) and fluid-blood lactate ratio (LacFB ratio) were calculated. A statistical analysis was carried out for fluid lactate (LacF), \u0394LacFB, and LacFB ratio, performing ROC curves to find the cut-off values with best sensitivity (Sn) and specificity (Sp) predicting an exudate diagnosis: LacF: cut-off value: 2.4\u00a0mmol/L; AU-ROC 0.854 95% CI 0.756-0.952; Sn 0.77; Sp 0.84. \u0394LacFB: cut-off value: 0.95\u00a0mmol/L; Au-ROC 0.876 95% CI 0.785-0.966; Sn 0.80; Sp 0.92. LacFB ratio: cut-off value: 2\u00a0mmol/L; Au-ROC 0.730 95% CI 0.609-0.851; Sn 0.74; Sp 0.65. Lactate dosage by blood-gas analyzer on pleural and abdominal effusions seems to be a promising tool to predict a diagnosis of exudate.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s11739-017-1757-y", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1295016", 
        "issn": [
          "1828-0447", 
          "1970-9366"
        ], 
        "name": "Internal and Emergency Medicine", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "6", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "13"
      }
    ], 
    "name": "Lactate determination in pleural and abdominal effusions: a quick diagnostic marker of exudate\u2014a pilot study", 
    "pagination": "901-906", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "44e040c893dc4af8f44b194080d5947d206a013edca2b5354cece9071bbe106e"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "28965174"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101263418"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s11739-017-1757-y"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1092002795"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s11739-017-1757-y", 
      "https://app.dimensions.ai/details/publication/pub.1092002795"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T21:48", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8687_00000570.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1007%2Fs11739-017-1757-y"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s11739-017-1757-y'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s11739-017-1757-y'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s11739-017-1757-y'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s11739-017-1757-y'


 

This table displays all metadata directly associated to this object as RDF triples.

306 TRIPLES      21 PREDICATES      80 URIs      21 LITERALS      9 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s11739-017-1757-y schema:about anzsrc-for:11
2 anzsrc-for:1103
3 schema:author N73c7374941d441c4b130634e9c0a933b
4 schema:citation sg:pub.10.1007/bf01645433
5 sg:pub.10.1007/bf02013087
6 sg:pub.10.1038/nchembio.971
7 sg:pub.10.1186/cc1509
8 sg:pub.10.1186/s12879-016-1818-2
9 https://app.dimensions.ai/details/publication/pub.1075055698
10 https://app.dimensions.ai/details/publication/pub.1076831901
11 https://app.dimensions.ai/details/publication/pub.1078158550
12 https://app.dimensions.ai/details/publication/pub.1078763664
13 https://app.dimensions.ai/details/publication/pub.1079032077
14 https://app.dimensions.ai/details/publication/pub.1079266830
15 https://app.dimensions.ai/details/publication/pub.1079878470
16 https://app.dimensions.ai/details/publication/pub.1081999592
17 https://doi.org/10.1001/archinte.132.6.854
18 https://doi.org/10.1001/archinte.1970.00310080075009
19 https://doi.org/10.1001/archinte.1973.03650120060011
20 https://doi.org/10.1001/jama.1973.03220300019004
21 https://doi.org/10.1002/1097-0142(196003/04)13:2<283::aid-cncr2820130212>3.0.co;2-2
22 https://doi.org/10.1002/hep.1840010310
23 https://doi.org/10.1002/hep.1840040316
24 https://doi.org/10.1016/0002-9343(84)90542-4
25 https://doi.org/10.1016/0016-5085(90)91300-u
26 https://doi.org/10.1016/0736-4679(84)90005-2
27 https://doi.org/10.1016/s0749-0704(18)30516-5
28 https://doi.org/10.1056/nejmcp010731
29 https://doi.org/10.1056/nejmra1309483
30 https://doi.org/10.1080/00365540110076732
31 https://doi.org/10.1093/clinids/3.3.470
32 https://doi.org/10.1097/00005768-200004000-00011
33 https://doi.org/10.1097/00024382-200014010-00002
34 https://doi.org/10.1097/ccm.0b013e31827e83af
35 https://doi.org/10.1097/pcc.0b013e3182196aa2
36 https://doi.org/10.1097/shk.0b013e318167378f
37 https://doi.org/10.1111/j.1699-0463.1984.tb02799.x
38 https://doi.org/10.1113/jphysiol.2009.178350
39 https://doi.org/10.1136/thx.58.suppl_2.ii8
40 https://doi.org/10.1159/000194067
41 https://doi.org/10.1159/000194303
42 https://doi.org/10.1159/000194802
43 https://doi.org/10.1159/000196392
44 https://doi.org/10.1164/ajrccm/139.3.663
45 https://doi.org/10.1164/arrd.1978.117.4.665
46 https://doi.org/10.1172/jci110647
47 https://doi.org/10.1183/09031936.00.15116600
48 https://doi.org/10.1378/chest.15-1703
49 https://doi.org/10.1378/chest.70.3.328
50 https://doi.org/10.1378/chest.92.2.296
51 https://doi.org/10.3109/00365548809117222
52 https://doi.org/10.7326/0003-4819-110-7-567
53 https://doi.org/10.7326/0003-4819-76-6-985
54 https://doi.org/10.7326/0003-4819-77-4-507
55 schema:datePublished 2018-09
56 schema:datePublishedReg 2018-09-01
57 schema:description Pleural or abdominal effusions are frequent findings in ICU and Internal Medicine patients. Diagnostic gold standard to distinguish between transudate and exudate is represented by "Light's Criteria," but, unfortunately, the chemical-physical examination for their calculation is not a rapid test. Pursuing an acid-base assessment of the fluid by a blood-gas analyzer, an increase of lactate beyond the normal serum range is reported in the exudative effusions. The advantages of this test are that it is a very fast bed-side test, executable directly by the physician. The aim of this study is to evaluate whether the increase in lactate in pleural and abdominal effusions might be used as a criterion for the differential diagnosis of the nature of the fluid. Sixty-nine patients with pleural or abdominal effusions and clinical indication for thoracentesis or paracentesis were enrolled. Acid-base assessment with lactate, total protein, and LDH dosage on the serum, and acid-base assessment with lactate, total protein, and LDH dosage, cytology, and bacterial culture on the fluid were performed to each patient. Fluid-blood lactate difference (ΔLacFB) and fluid-blood lactate ratio (LacFB ratio) were calculated. A statistical analysis was carried out for fluid lactate (LacF), ΔLacFB, and LacFB ratio, performing ROC curves to find the cut-off values with best sensitivity (Sn) and specificity (Sp) predicting an exudate diagnosis: LacF: cut-off value: 2.4 mmol/L; AU-ROC 0.854 95% CI 0.756-0.952; Sn 0.77; Sp 0.84. ΔLacFB: cut-off value: 0.95 mmol/L; Au-ROC 0.876 95% CI 0.785-0.966; Sn 0.80; Sp 0.92. LacFB ratio: cut-off value: 2 mmol/L; Au-ROC 0.730 95% CI 0.609-0.851; Sn 0.74; Sp 0.65. Lactate dosage by blood-gas analyzer on pleural and abdominal effusions seems to be a promising tool to predict a diagnosis of exudate.
58 schema:genre research_article
59 schema:inLanguage en
60 schema:isAccessibleForFree false
61 schema:isPartOf N19a089ff726b44ddba13d3bb61789207
62 N8b48e78d3ff044be92dc3603bce59108
63 sg:journal.1295016
64 schema:name Lactate determination in pleural and abdominal effusions: a quick diagnostic marker of exudate—a pilot study
65 schema:pagination 901-906
66 schema:productId N0ce0fe50e67542ee9d3700a4160e64e3
67 N1ffad87585194e9e96e82789ca42ff5c
68 N5249c2fc1d734ed6a19e341a232d083b
69 N7040b7713c2241b78b2df1d830bfe06a
70 N706a4a512fdd430f86e0c974d8c03d54
71 schema:sameAs https://app.dimensions.ai/details/publication/pub.1092002795
72 https://doi.org/10.1007/s11739-017-1757-y
73 schema:sdDatePublished 2019-04-10T21:48
74 schema:sdLicense https://scigraph.springernature.com/explorer/license/
75 schema:sdPublisher Nd95e48cae25949deaad81617e55731a1
76 schema:url https://link.springer.com/10.1007%2Fs11739-017-1757-y
77 sgo:license sg:explorer/license/
78 sgo:sdDataset articles
79 rdf:type schema:ScholarlyArticle
80 N02ac7ab424254e2d8f57801be970cea2 rdf:first sg:person.01342415642.47
81 rdf:rest N3fa52a3a07cb4823a0384585fb79b8d6
82 N0cd2616e673c46a8836aa24804877eed rdf:first sg:person.016613064424.21
83 rdf:rest N02ac7ab424254e2d8f57801be970cea2
84 N0ce0fe50e67542ee9d3700a4160e64e3 schema:name pubmed_id
85 schema:value 28965174
86 rdf:type schema:PropertyValue
87 N19a089ff726b44ddba13d3bb61789207 schema:issueNumber 6
88 rdf:type schema:PublicationIssue
89 N1ffad87585194e9e96e82789ca42ff5c schema:name nlm_unique_id
90 schema:value 101263418
91 rdf:type schema:PropertyValue
92 N358c04b9079b438bbaaa9a00a0a77bbd rdf:first sg:person.0724642714.36
93 rdf:rest Nddf1a8998a9643b0a2b0310b4a17809d
94 N3fa52a3a07cb4823a0384585fb79b8d6 rdf:first sg:person.0701071407.40
95 rdf:rest Nd83247358d934c07908a36a888c42313
96 N5249c2fc1d734ed6a19e341a232d083b schema:name readcube_id
97 schema:value 44e040c893dc4af8f44b194080d5947d206a013edca2b5354cece9071bbe106e
98 rdf:type schema:PropertyValue
99 N5d49b671d2c042b3965a36234c25a43b rdf:first sg:person.0707665661.15
100 rdf:rest N358c04b9079b438bbaaa9a00a0a77bbd
101 N6c0af2fd93da4893bed2099d147a2c05 rdf:first sg:person.01274324107.13
102 rdf:rest Nf83e80275c9e444cb7f0f10158e01461
103 N7040b7713c2241b78b2df1d830bfe06a schema:name dimensions_id
104 schema:value pub.1092002795
105 rdf:type schema:PropertyValue
106 N706a4a512fdd430f86e0c974d8c03d54 schema:name doi
107 schema:value 10.1007/s11739-017-1757-y
108 rdf:type schema:PropertyValue
109 N73c7374941d441c4b130634e9c0a933b rdf:first sg:person.0744267626.57
110 rdf:rest N0cd2616e673c46a8836aa24804877eed
111 N8b48e78d3ff044be92dc3603bce59108 schema:volumeNumber 13
112 rdf:type schema:PublicationVolume
113 Nc93d7d4dc12d4c57b3bce727a1ebafab rdf:first sg:person.011350513023.14
114 rdf:rest Ne381a87568814f93bcfded179de15cc4
115 Nd83247358d934c07908a36a888c42313 rdf:first sg:person.047374530.79
116 rdf:rest Nc93d7d4dc12d4c57b3bce727a1ebafab
117 Nd95e48cae25949deaad81617e55731a1 schema:name Springer Nature - SN SciGraph project
118 rdf:type schema:Organization
119 Nddf1a8998a9643b0a2b0310b4a17809d rdf:first sg:person.011777676161.16
120 rdf:rest N6c0af2fd93da4893bed2099d147a2c05
121 Ne381a87568814f93bcfded179de15cc4 rdf:first sg:person.015441712043.98
122 rdf:rest N5d49b671d2c042b3965a36234c25a43b
123 Ne5cdc1848efe4bb29cdc0f2939bf5d5f schema:name Emergency Department, “San Paolo” Hospital, Naples, Italy
124 rdf:type schema:Organization
125 Nf278930e9cce40608f392ac8695c1eb9 schema:name Emergency Department, “San Paolo” Hospital, Naples, Italy
126 rdf:type schema:Organization
127 Nf83e80275c9e444cb7f0f10158e01461 rdf:first sg:person.01123750475.74
128 rdf:rest rdf:nil
129 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
130 schema:name Medical and Health Sciences
131 rdf:type schema:DefinedTerm
132 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
133 schema:name Clinical Sciences
134 rdf:type schema:DefinedTerm
135 sg:journal.1295016 schema:issn 1828-0447
136 1970-9366
137 schema:name Internal and Emergency Medicine
138 rdf:type schema:Periodical
139 sg:person.01123750475.74 schema:affiliation Ne5cdc1848efe4bb29cdc0f2939bf5d5f
140 schema:familyName Schiraldi
141 schema:givenName Fernando
142 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01123750475.74
143 rdf:type schema:Person
144 sg:person.011350513023.14 schema:affiliation https://www.grid.ac/institutes/grid.413172.2
145 schema:familyName Bosso
146 schema:givenName Giorgio
147 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011350513023.14
148 rdf:type schema:Person
149 sg:person.011777676161.16 schema:affiliation https://www.grid.ac/institutes/grid.9841.4
150 schema:familyName Amelia
151 schema:givenName Annalisa
152 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011777676161.16
153 rdf:type schema:Person
154 sg:person.01274324107.13 schema:affiliation https://www.grid.ac/institutes/grid.413172.2
155 schema:familyName Paladino
156 schema:givenName Fiorella
157 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01274324107.13
158 rdf:type schema:Person
159 sg:person.01342415642.47 schema:affiliation https://www.grid.ac/institutes/grid.9841.4
160 schema:familyName Rosato
161 schema:givenName Valerio
162 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01342415642.47
163 rdf:type schema:Person
164 sg:person.015441712043.98 schema:affiliation https://www.grid.ac/institutes/grid.413172.2
165 schema:familyName Serra
166 schema:givenName Claudia
167 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015441712043.98
168 rdf:type schema:Person
169 sg:person.016613064424.21 schema:affiliation Nf278930e9cce40608f392ac8695c1eb9
170 schema:familyName Numis
171 schema:givenName Fabio G.
172 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016613064424.21
173 rdf:type schema:Person
174 sg:person.047374530.79 schema:affiliation https://www.grid.ac/institutes/grid.11780.3f
175 schema:familyName Masarone
176 schema:givenName Mario
177 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.047374530.79
178 rdf:type schema:Person
179 sg:person.0701071407.40 schema:affiliation https://www.grid.ac/institutes/grid.413172.2
180 schema:familyName Pagano
181 schema:givenName Antonio
182 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0701071407.40
183 rdf:type schema:Person
184 sg:person.0707665661.15 schema:affiliation https://www.grid.ac/institutes/grid.9841.4
185 schema:familyName Rinaldi
186 schema:givenName Luca
187 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0707665661.15
188 rdf:type schema:Person
189 sg:person.0724642714.36 schema:affiliation https://www.grid.ac/institutes/grid.9841.4
190 schema:familyName Fascione
191 schema:givenName Maria C.
192 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0724642714.36
193 rdf:type schema:Person
194 sg:person.0744267626.57 schema:affiliation https://www.grid.ac/institutes/grid.413172.2
195 schema:familyName Porta
196 schema:givenName Giovanni
197 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0744267626.57
198 rdf:type schema:Person
199 sg:pub.10.1007/bf01645433 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004071461
200 https://doi.org/10.1007/bf01645433
201 rdf:type schema:CreativeWork
202 sg:pub.10.1007/bf02013087 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035761786
203 https://doi.org/10.1007/bf02013087
204 rdf:type schema:CreativeWork
205 sg:pub.10.1038/nchembio.971 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024041597
206 https://doi.org/10.1038/nchembio.971
207 rdf:type schema:CreativeWork
208 sg:pub.10.1186/cc1509 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022962194
209 https://doi.org/10.1186/cc1509
210 rdf:type schema:CreativeWork
211 sg:pub.10.1186/s12879-016-1818-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045931266
212 https://doi.org/10.1186/s12879-016-1818-2
213 rdf:type schema:CreativeWork
214 https://app.dimensions.ai/details/publication/pub.1075055698 schema:CreativeWork
215 https://app.dimensions.ai/details/publication/pub.1076831901 schema:CreativeWork
216 https://app.dimensions.ai/details/publication/pub.1078158550 schema:CreativeWork
217 https://app.dimensions.ai/details/publication/pub.1078763664 schema:CreativeWork
218 https://app.dimensions.ai/details/publication/pub.1079032077 schema:CreativeWork
219 https://app.dimensions.ai/details/publication/pub.1079266830 schema:CreativeWork
220 https://app.dimensions.ai/details/publication/pub.1079878470 schema:CreativeWork
221 https://app.dimensions.ai/details/publication/pub.1081999592 schema:CreativeWork
222 https://doi.org/10.1001/archinte.132.6.854 schema:sameAs https://app.dimensions.ai/details/publication/pub.1054106371
223 rdf:type schema:CreativeWork
224 https://doi.org/10.1001/archinte.1970.00310080075009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026079198
225 rdf:type schema:CreativeWork
226 https://doi.org/10.1001/archinte.1973.03650120060011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023198977
227 rdf:type schema:CreativeWork
228 https://doi.org/10.1001/jama.1973.03220300019004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012388812
229 rdf:type schema:CreativeWork
230 https://doi.org/10.1002/1097-0142(196003/04)13:2<283::aid-cncr2820130212>3.0.co;2-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041517071
231 rdf:type schema:CreativeWork
232 https://doi.org/10.1002/hep.1840010310 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007949479
233 rdf:type schema:CreativeWork
234 https://doi.org/10.1002/hep.1840040316 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040617752
235 rdf:type schema:CreativeWork
236 https://doi.org/10.1016/0002-9343(84)90542-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025405416
237 rdf:type schema:CreativeWork
238 https://doi.org/10.1016/0016-5085(90)91300-u schema:sameAs https://app.dimensions.ai/details/publication/pub.1039027283
239 rdf:type schema:CreativeWork
240 https://doi.org/10.1016/0736-4679(84)90005-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007998919
241 rdf:type schema:CreativeWork
242 https://doi.org/10.1016/s0749-0704(18)30516-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1079690558
243 rdf:type schema:CreativeWork
244 https://doi.org/10.1056/nejmcp010731 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032329691
245 rdf:type schema:CreativeWork
246 https://doi.org/10.1056/nejmra1309483 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048905821
247 rdf:type schema:CreativeWork
248 https://doi.org/10.1080/00365540110076732 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021625024
249 rdf:type schema:CreativeWork
250 https://doi.org/10.1093/clinids/3.3.470 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059474567
251 rdf:type schema:CreativeWork
252 https://doi.org/10.1097/00005768-200004000-00011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002035239
253 rdf:type schema:CreativeWork
254 https://doi.org/10.1097/00024382-200014010-00002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008420682
255 rdf:type schema:CreativeWork
256 https://doi.org/10.1097/ccm.0b013e31827e83af schema:sameAs https://app.dimensions.ai/details/publication/pub.1014463755
257 rdf:type schema:CreativeWork
258 https://doi.org/10.1097/pcc.0b013e3182196aa2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016428633
259 rdf:type schema:CreativeWork
260 https://doi.org/10.1097/shk.0b013e318167378f schema:sameAs https://app.dimensions.ai/details/publication/pub.1004099275
261 rdf:type schema:CreativeWork
262 https://doi.org/10.1111/j.1699-0463.1984.tb02799.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1006410938
263 rdf:type schema:CreativeWork
264 https://doi.org/10.1113/jphysiol.2009.178350 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042721678
265 rdf:type schema:CreativeWork
266 https://doi.org/10.1136/thx.58.suppl_2.ii8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021024807
267 rdf:type schema:CreativeWork
268 https://doi.org/10.1159/000194067 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033392266
269 rdf:type schema:CreativeWork
270 https://doi.org/10.1159/000194303 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017272538
271 rdf:type schema:CreativeWork
272 https://doi.org/10.1159/000194802 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046693191
273 rdf:type schema:CreativeWork
274 https://doi.org/10.1159/000196392 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053668512
275 rdf:type schema:CreativeWork
276 https://doi.org/10.1164/ajrccm/139.3.663 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016902211
277 rdf:type schema:CreativeWork
278 https://doi.org/10.1164/arrd.1978.117.4.665 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049245797
279 rdf:type schema:CreativeWork
280 https://doi.org/10.1172/jci110647 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003994047
281 rdf:type schema:CreativeWork
282 https://doi.org/10.1183/09031936.00.15116600 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037176466
283 rdf:type schema:CreativeWork
284 https://doi.org/10.1378/chest.15-1703 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049375781
285 rdf:type schema:CreativeWork
286 https://doi.org/10.1378/chest.70.3.328 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030301493
287 rdf:type schema:CreativeWork
288 https://doi.org/10.1378/chest.92.2.296 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027084093
289 rdf:type schema:CreativeWork
290 https://doi.org/10.3109/00365548809117222 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040683049
291 rdf:type schema:CreativeWork
292 https://doi.org/10.7326/0003-4819-110-7-567 schema:sameAs https://app.dimensions.ai/details/publication/pub.1073693858
293 rdf:type schema:CreativeWork
294 https://doi.org/10.7326/0003-4819-76-6-985 schema:sameAs https://app.dimensions.ai/details/publication/pub.1073730041
295 rdf:type schema:CreativeWork
296 https://doi.org/10.7326/0003-4819-77-4-507 schema:sameAs https://app.dimensions.ai/details/publication/pub.1073730288
297 rdf:type schema:CreativeWork
298 https://www.grid.ac/institutes/grid.11780.3f schema:alternateName University of Salerno
299 schema:name Internal Medicine and Hepatology Unit, University of Salerno, Baronissi, Italy
300 rdf:type schema:Organization
301 https://www.grid.ac/institutes/grid.413172.2 schema:alternateName Ospedale Antonio Cardarelli
302 schema:name Emergency Department, “A. Cardarelli” Hospital, Via Cardarelli 9, 80131, Naples, Italy
303 rdf:type schema:Organization
304 https://www.grid.ac/institutes/grid.9841.4 schema:alternateName Second University of Naples
305 schema:name Internal Medicine and Hepatology Department, Second University of Naples, Naples, Italy
306 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...