Ontology type: schema:ScholarlyArticle
2018-12
AUTHORSFerran Rius, Enric Sánchez, Àngels Betriu, Juan Antonio Baena-Fustegueras, Andree Yeramian, Teresa Vidal, Marta Hernández, Carolina López-Cano, Marta Bueno, Liliana Gutiérrez-Carrasquilla, Ferran Herrerías, Mari Cruz de la Fuente, Elvira Fernández, Albert Lecube
ABSTRACTINTRODUCTION/PURPOSE: Adventitial vasa vasorum (VV) expansion to the avascular intima precedes an increase in carotid intima-media thickness. However, factors involved in the development of the atherosclerotic process and its reversibility remain unclear. We aimed to evaluate the VV signal in both morbid obesity and after bariatric surgery (BS). MATERIALS/METHODS: We conducted a case-control study to examine the VV signal in the carotid of 40 morbidly obese patients and 40 non-obese controls. The effect of BS was evaluated in 33 patients. Contrast-enhanced carotid ultrasound was used to assess the VV signal. RESULTS: The mean VV density was higher in obese than in non-obese subjects (0.739 ± 0.117 vs. 0.570 ± 0.111, p < 0.001). The VV signal positively correlated with BMI (p < 0.001) and waist circumference (p = 0.001) but was not related to cIMT. The stepwise multivariate regression analysis revealed that waist circumference (beta = 0.507, p < 0.001) together with fasting plasma glucose (beta = 0.229, p = 0.024) were independently associated with the VV signal (R2 = 0.382). Before BS, the median VV signal correlated with soluble intercellular adhesion molecule 1 (p = 0.022). After a 12-month follow-up, a 12.0% decrease in VV (0.731 ± 0.126 vs. 0.643 ± 0.115, p = 0.003) was observed. In the univariate analysis, the decrease in VV was associated with the baseline VV density (p < 0.001), baseline systolic blood pressure (p = 0.019) and a decrease in sICAM (p = 0.005). However, only baseline systolic pressure (beta = 0.417, p = 0.024) independently predicted the absolute change in VV signal (R2 = 0.174). CONCLUSIONS: Morbidly obesity is associated with increased VV density. In addition, BS appears to reduce the earlier expansion of the adventitial vasa vasorum. More... »
PAGES3935-3942
http://scigraph.springernature.com/pub.10.1007/s11695-018-3410-x
DOIhttp://dx.doi.org/10.1007/s11695-018-3410-x
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1105734398
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/30030728
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Clinical Sciences",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Medical and Health Sciences",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"name": [
"Endocrinology and Nutrition Department, University Hospital Arnau de Vilanova, Obesity, Diabetes and Metabolism Research Group (ODIM), IRBLleida, University of Lleida, Av. Rovira Roure 80, 25198, Lleida, Spain"
],
"type": "Organization"
},
"familyName": "Rius",
"givenName": "Ferran",
"id": "sg:person.01127466300.87",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01127466300.87"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"Endocrinology and Nutrition Department, University Hospital Arnau de Vilanova, Obesity, Diabetes and Metabolism Research Group (ODIM), IRBLleida, University of Lleida, Av. Rovira Roure 80, 25198, Lleida, Spain"
],
"type": "Organization"
},
"familyName": "S\u00e1nchez",
"givenName": "Enric",
"id": "sg:person.015011376301.82",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015011376301.82"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"Unit for the Detection and the Treatment of Atherothrombotic Diseases (UDETMAV&R), University Hospital Arnau de Vilanova, Vascular and Renal Translational Research Group, IRBLleida, University of Lleida, Lleida, Spain"
],
"type": "Organization"
},
"familyName": "Betriu",
"givenName": "\u00c0ngels",
"id": "sg:person.012665430624.17",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012665430624.17"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"Gastrointestinal Surgery Department, University Hospital Arnau de Vilanova, IRBLleida, University of Lleida, Lleida, Spain"
],
"type": "Organization"
},
"familyName": "Baena-Fustegueras",
"givenName": "Juan Antonio",
"id": "sg:person.01062671123.99",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01062671123.99"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"Endocrinology and Nutrition Department, University Hospital Arnau de Vilanova, Obesity, Diabetes and Metabolism Research Group (ODIM), IRBLleida, University of Lleida, Av. Rovira Roure 80, 25198, Lleida, Spain"
],
"type": "Organization"
},
"familyName": "Yeramian",
"givenName": "Andree",
"id": "sg:person.01072106301.07",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01072106301.07"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"Unit for the Detection and the Treatment of Atherothrombotic Diseases (UDETMAV&R), University Hospital Arnau de Vilanova, Vascular and Renal Translational Research Group, IRBLleida, University of Lleida, Lleida, Spain"
],
"type": "Organization"
},
"familyName": "Vidal",
"givenName": "Teresa",
"id": "sg:person.01335474311.08",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01335474311.08"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"Endocrinology and Nutrition Department, University Hospital Arnau de Vilanova, Obesity, Diabetes and Metabolism Research Group (ODIM), IRBLleida, University of Lleida, Av. Rovira Roure 80, 25198, Lleida, Spain"
],
"type": "Organization"
},
"familyName": "Hern\u00e1ndez",
"givenName": "Marta",
"id": "sg:person.01254641732.59",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01254641732.59"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"Endocrinology and Nutrition Department, University Hospital Arnau de Vilanova, Obesity, Diabetes and Metabolism Research Group (ODIM), IRBLleida, University of Lleida, Av. Rovira Roure 80, 25198, Lleida, Spain"
],
"type": "Organization"
},
"familyName": "L\u00f3pez-Cano",
"givenName": "Carolina",
"id": "sg:person.013025743421.83",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013025743421.83"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"Endocrinology and Nutrition Department, University Hospital Arnau de Vilanova, Obesity, Diabetes and Metabolism Research Group (ODIM), IRBLleida, University of Lleida, Av. Rovira Roure 80, 25198, Lleida, Spain"
],
"type": "Organization"
},
"familyName": "Bueno",
"givenName": "Marta",
"id": "sg:person.014227077411.73",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014227077411.73"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"Endocrinology and Nutrition Department, University Hospital Arnau de Vilanova, Obesity, Diabetes and Metabolism Research Group (ODIM), IRBLleida, University of Lleida, Av. Rovira Roure 80, 25198, Lleida, Spain"
],
"type": "Organization"
},
"familyName": "Guti\u00e9rrez-Carrasquilla",
"givenName": "Liliana",
"id": "sg:person.011366450376.49",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011366450376.49"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"Gastrointestinal Surgery Department, University Hospital Arnau de Vilanova, IRBLleida, University of Lleida, Lleida, Spain"
],
"type": "Organization"
},
"familyName": "Herrer\u00edas",
"givenName": "Ferran",
"type": "Person"
},
{
"affiliation": {
"name": [
"Gastrointestinal Surgery Department, University Hospital Arnau de Vilanova, IRBLleida, University of Lleida, Lleida, Spain"
],
"type": "Organization"
},
"familyName": "de la Fuente",
"givenName": "Mari Cruz",
"type": "Person"
},
{
"affiliation": {
"name": [
"Unit for the Detection and the Treatment of Atherothrombotic Diseases (UDETMAV&R), University Hospital Arnau de Vilanova, Vascular and Renal Translational Research Group, IRBLleida, University of Lleida, Lleida, Spain"
],
"type": "Organization"
},
"familyName": "Fern\u00e1ndez",
"givenName": "Elvira",
"id": "sg:person.0606403360.16",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0606403360.16"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Instituto de Salud Carlos III",
"id": "https://www.grid.ac/institutes/grid.413448.e",
"name": [
"Endocrinology and Nutrition Department, University Hospital Arnau de Vilanova, Obesity, Diabetes and Metabolism Research Group (ODIM), IRBLleida, University of Lleida, Av. Rovira Roure 80, 25198, Lleida, Spain",
"Centro de Investigaci\u00f3n en Red en Diabetes y Enfermedades Metab\u00f3licas Asociadas (CIBERDEM), Instituto de Salud Carlos III (ISCIII), Madrid, Spain"
],
"type": "Organization"
},
"familyName": "Lecube",
"givenName": "Albert",
"id": "sg:person.01177117523.37",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01177117523.37"
],
"type": "Person"
}
],
"citation": [
{
"id": "https://doi.org/10.1016/j.cjca.2014.12.008",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1000391045"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0140-6736(16)30054-x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1004704916"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/1060028014529260",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1008222064"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/1060028014529260",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1008222064"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1515/hmbci-2014-0009",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1008781171"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1001/jama.2011.1914",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1011013383"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/path.1711710311",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1012098349"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/path.1711710311",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1012098349"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.tcm.2015.07.006",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1014303620"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.atherosclerosis.2013.02.011",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1017683084"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/ijo.2015.187",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1017852207",
"https://doi.org/10.1038/ijo.2015.187"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s11883-008-0068-1",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1018871371",
"https://doi.org/10.1007/s11883-008-0068-1"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.jacc.2006.02.068",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1020702589"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s11695-012-0862-2",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1021795331",
"https://doi.org/10.1007/s11695-012-0862-2"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1056/nejmsr043743",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1021872967"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/echo.12646",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1024458454"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1467-789x.2010.00831.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1025484916"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/eji.1830221009",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1027926163"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0140-6736(09)60318-4",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1028703720"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0021-9150(03)00097-2",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1028793372"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0021-9150(03)00097-2",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1028793372"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s11695-016-2279-9",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1031717791",
"https://doi.org/10.1007/s11695-016-2279-9"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s11695-016-2279-9",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1031717791",
"https://doi.org/10.1007/s11695-016-2279-9"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1161/01.cir.0000025636.03561.ee",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1032057406"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1161/01.cir.0000146787.16297.e8",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1032191092"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/oby.20357",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1033920751"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0140-6736(07)61602-x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1036200026"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1186/s12947-015-0014-7",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1037448954",
"https://doi.org/10.1186/s12947-015-0014-7"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1186/s12947-015-0014-7",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1037448954",
"https://doi.org/10.1186/s12947-015-0014-7"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.cmet.2013.03.008",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1038120471"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1056/nejmoa066254",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1040668492"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.5853/jos.2013.15.1.38",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1042812223"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.drudis.2016.05.017",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1046971087"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.atherosclerosis.2015.05.024",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1047930603"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1161/circulationaha.104.513085",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1052789814"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1155/2017/3795142",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1053048352"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.2174/1381612811319320007",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1069169144"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/ajcn/55.2.615s",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1077378984"
],
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1078521914",
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1152/ajpcell.00158.2016",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1091248091"
],
"type": "CreativeWork"
}
],
"datePublished": "2018-12",
"datePublishedReg": "2018-12-01",
"description": "INTRODUCTION/PURPOSE: Adventitial vasa vasorum (VV) expansion to the avascular intima precedes an increase in carotid intima-media thickness. However, factors involved in the development of the atherosclerotic process and its reversibility remain unclear. We aimed to evaluate the VV signal in both morbid obesity and after bariatric surgery (BS).\nMATERIALS/METHODS: We conducted a case-control study to examine the VV signal in the carotid of 40 morbidly obese patients and 40 non-obese controls. The effect of BS was evaluated in 33 patients. Contrast-enhanced carotid ultrasound was used to assess the VV signal.\nRESULTS: The mean VV density was higher in obese than in non-obese subjects (0.739\u2009\u00b1\u20090.117 vs. 0.570\u2009\u00b1\u20090.111, p\u2009<\u20090.001). The VV signal positively correlated with BMI (p\u2009<\u20090.001) and waist circumference (p\u2009=\u20090.001) but was not related to cIMT. The stepwise multivariate regression analysis revealed that waist circumference (beta\u2009=\u20090.507, p\u2009<\u20090.001) together with fasting plasma glucose (beta\u2009=\u20090.229, p\u2009=\u20090.024) were independently associated with the VV signal (R2\u2009=\u20090.382). Before BS, the median VV signal correlated with soluble intercellular adhesion molecule 1 (p\u2009=\u20090.022). After a 12-month follow-up, a 12.0% decrease in VV (0.731\u2009\u00b1\u20090.126 vs. 0.643\u2009\u00b1\u20090.115, p\u2009=\u20090.003) was observed. In the univariate analysis, the decrease in VV was associated with the baseline VV density (p\u2009<\u20090.001), baseline systolic blood pressure (p\u2009=\u20090.019) and a decrease in sICAM (p\u2009=\u20090.005). However, only baseline systolic pressure (beta\u2009=\u20090.417, p\u2009=\u20090.024) independently predicted the absolute change in VV signal (R2\u2009=\u20090.174).\nCONCLUSIONS: Morbidly obesity is associated with increased VV density. In addition, BS appears to reduce the earlier expansion of the adventitial vasa vasorum.",
"genre": "research_article",
"id": "sg:pub.10.1007/s11695-018-3410-x",
"inLanguage": [
"en"
],
"isAccessibleForFree": false,
"isPartOf": [
{
"id": "sg:journal.1101268",
"issn": [
"0960-8923",
"1708-0428"
],
"name": "Obesity Surgery",
"type": "Periodical"
},
{
"issueNumber": "12",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "28"
}
],
"name": "Influence of Morbid Obesity and Bariatric Surgery Impact on the Carotid Adventitial Vasa Vasorum Signal",
"pagination": "3935-3942",
"productId": [
{
"name": "readcube_id",
"type": "PropertyValue",
"value": [
"43e4664a4619872b0bcdede26e8ae29c26468c3e3f1ac82780ed652d68d5a926"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"30030728"
]
},
{
"name": "nlm_unique_id",
"type": "PropertyValue",
"value": [
"9106714"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1007/s11695-018-3410-x"
]
},
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1105734398"
]
}
],
"sameAs": [
"https://doi.org/10.1007/s11695-018-3410-x",
"https://app.dimensions.ai/details/publication/pub.1105734398"
],
"sdDataset": "articles",
"sdDatePublished": "2019-04-10T21:55",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8687_00000609.jsonl",
"type": "ScholarlyArticle",
"url": "https://link.springer.com/10.1007%2Fs11695-018-3410-x"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s11695-018-3410-x'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s11695-018-3410-x'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s11695-018-3410-x'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s11695-018-3410-x'
This table displays all metadata directly associated to this object as RDF triples.
294 TRIPLES
21 PREDICATES
64 URIs
21 LITERALS
9 BLANK NODES