Bariatric Surgery Resistance: Using Preoperative Lifestyle Medicine and/or Pharmacology for Metabolic Responsiveness View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2017-12

AUTHORS

Nicole M. Gilbertson, Andrew S. Paisley, Sibylle Kranz, Arthur Weltman, Jennifer L. Kirby, Peter T. Hallowell, Steven K. Malin

ABSTRACT

Bariatric surgery is an effective and durable treatment for individuals with obesity and its associated comorbidities. However, not all patients meet weight loss and/or cardiometabolic goals following bariatric surgery, suggesting that some people are bariatric surgery resistant. The reason for this resistance is unclear, but potential factors, such as adiposity-derived inflammation, insulin resistance, hyperglycemia, and aerobic fitness prior to surgery, have been related to blunted surgery responsiveness. Exercise, diet, and/or pharmacology are effective at reducing inflammation and improving insulin action as well as physical function. Herein, we present data that supports the novel hypothesis that intervening prior to surgery can enhance disease resolution in people who are resistant to bariatric surgery. More... »

PAGES

3281-3291

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s11695-017-2966-1

    DOI

    http://dx.doi.org/10.1007/s11695-017-2966-1

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1092340848

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/29058238


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