Atherogenic Dyslipidemia Remission 1 Year After Bariatric Surgery View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2016-12-17

AUTHORS

Elisenda Climent, David Benaiges, Juan Pedro-Botet, Juana A. Flores-Le Roux, Jose M. Ramón, Montserrat Villatoro, Laia Fontané, Juan J. Chillarón, Albert Goday

ABSTRACT

PurposeGiven the lack of evidence of the effect of bariatric surgery (BS) on atherogenic dyslipidemia (AD), which is a characteristic of obese subjects, this study aimed to describe the remission rate of AD 1 year after BS in severely obese patients.Materials and MethodsA non-randomised, prospective cohort study was conducted in patients undergoing laparoscopic Roux-en-Y gastric bypass or laparoscopic sleeve gastrectomy with a 1-year follow-up. AD was defined as triglycerides ≥1.71 mmol/l or treatment with fibrates and low high-density lipoprotein (HDL) cholesterol (<1.03 mmol/l in men or <1.3 mmol/l in women).ResultsAD was present in 81 (22.8%) of the 356 patients; these were more frequently men and presented higher total cholesterol and non-HDL cholesterol concentrations. AD remission rate was 74.1% at 3 months, 90.1% at 6 months and 96.3% at 12 months, respectively, after BS. In this group of patients, HDL cholesterol levels rose progressively (1.0 ± 0.2 to 1.5 ± 0.3 mmol/l, p < 0.001) and triglycerides decreased (2.5 ± 0.9 to 1.2 ± 0.5 mmol/l, p < 0.001) during follow-up. Regarding previous lipid-lowering therapy, fibrates and ezetimibe were withdrawn in all patients and statins in 69.4% 1 year after surgery.ConclusionBS has beneficial effects on lipid profile, achieving complete remission of AD at 1 year of follow-up in almost all patients. More... »

PAGES

1548-1553

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11695-016-2504-6

DOI

http://dx.doi.org/10.1007/s11695-016-2504-6

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1009493666

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/27988827


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Atherosclerosis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Dyslipidemias", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gastrectomy", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gastric Bypass", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Obesity, Morbid", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Prospective Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Remission Induction", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Triglycerides", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Weight Loss", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Medicine, Universitat Aut\u00f2noma de Barcelona, Campus Universitari Mar. Dr. Aiguader, 80, E-08003, Barcelona, Spain", 
          "id": "http://www.grid.ac/institutes/grid.7080.f", 
          "name": [
            "Department of Endocrinology and Nutrition, Hospital del Mar, Paseo Mar\u00edtimo, 25-29, E-08003, Barcelona, Spain", 
            "Department of Medicine, Universitat Aut\u00f2noma de Barcelona, Campus Universitari Mar. Dr. Aiguader, 80, E-08003, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Climent", 
        "givenName": "Elisenda", 
        "id": "sg:person.01173213347.44", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01173213347.44"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Hospital del Mar d\u2019Investigacions M\u00e8diques (IMIM), Dr. Aiguader, 80, E-08003, Barcelona, Spain", 
          "id": "http://www.grid.ac/institutes/grid.20522.37", 
          "name": [
            "Department of Endocrinology and Nutrition, Hospital del Mar, Paseo Mar\u00edtimo, 25-29, E-08003, Barcelona, Spain", 
            "Department of Medicine, Universitat Aut\u00f2noma de Barcelona, Campus Universitari Mar. Dr. Aiguader, 80, E-08003, Barcelona, Spain", 
            "Institut Hospital del Mar d\u2019Investigacions M\u00e8diques (IMIM), Dr. Aiguader, 80, E-08003, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Benaiges", 
        "givenName": "David", 
        "id": "sg:person.01173500354.32", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01173500354.32"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Hospital del Mar d\u2019Investigacions M\u00e8diques (IMIM), Dr. Aiguader, 80, E-08003, Barcelona, Spain", 
          "id": "http://www.grid.ac/institutes/grid.20522.37", 
          "name": [
            "Department of Endocrinology and Nutrition, Hospital del Mar, Paseo Mar\u00edtimo, 25-29, E-08003, Barcelona, Spain", 
            "Department of Medicine, Universitat Aut\u00f2noma de Barcelona, Campus Universitari Mar. Dr. Aiguader, 80, E-08003, Barcelona, Spain", 
            "Institut Hospital del Mar d\u2019Investigacions M\u00e8diques (IMIM), Dr. Aiguader, 80, E-08003, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pedro-Botet", 
        "givenName": "Juan", 
        "id": "sg:person.01301600460.81", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01301600460.81"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Hospital del Mar d\u2019Investigacions M\u00e8diques (IMIM), Dr. Aiguader, 80, E-08003, Barcelona, Spain", 
          "id": "http://www.grid.ac/institutes/grid.20522.37", 
          "name": [
            "Department of Endocrinology and Nutrition, Hospital del Mar, Paseo Mar\u00edtimo, 25-29, E-08003, Barcelona, Spain", 
            "Department of Medicine, Universitat Aut\u00f2noma de Barcelona, Campus Universitari Mar. Dr. Aiguader, 80, E-08003, Barcelona, Spain", 
            "Institut Hospital del Mar d\u2019Investigacions M\u00e8diques (IMIM), Dr. Aiguader, 80, E-08003, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Flores-Le Roux", 
        "givenName": "Juana A.", 
        "id": "sg:person.01235473723.90", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01235473723.90"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of General Surgery, Hospital del Mar, Paseo Mar\u00edtimo, 25-29, E-08003, Barcelona, Spain", 
          "id": "http://www.grid.ac/institutes/grid.411142.3", 
          "name": [
            "Institut Hospital del Mar d\u2019Investigacions M\u00e8diques (IMIM), Dr. Aiguader, 80, E-08003, Barcelona, Spain", 
            "Department of General Surgery, Hospital del Mar, Paseo Mar\u00edtimo, 25-29, E-08003, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ram\u00f3n", 
        "givenName": "Jose M.", 
        "id": "sg:person.01312131655.72", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01312131655.72"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Endocrinology and Nutrition, Hospital del Mar, Paseo Mar\u00edtimo, 25-29, E-08003, Barcelona, Spain", 
          "id": "http://www.grid.ac/institutes/grid.411142.3", 
          "name": [
            "Department of Endocrinology and Nutrition, Hospital del Mar, Paseo Mar\u00edtimo, 25-29, E-08003, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Villatoro", 
        "givenName": "Montserrat", 
        "id": "sg:person.0771055147.50", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0771055147.50"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Endocrinology and Nutrition, Hospital del Mar, Paseo Mar\u00edtimo, 25-29, E-08003, Barcelona, Spain", 
          "id": "http://www.grid.ac/institutes/grid.411142.3", 
          "name": [
            "Department of Endocrinology and Nutrition, Hospital del Mar, Paseo Mar\u00edtimo, 25-29, E-08003, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fontan\u00e9", 
        "givenName": "Laia", 
        "id": "sg:person.016161272315.22", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016161272315.22"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut Hospital del Mar d\u2019Investigacions M\u00e8diques (IMIM), Dr. Aiguader, 80, E-08003, Barcelona, Spain", 
          "id": "http://www.grid.ac/institutes/grid.20522.37", 
          "name": [
            "Department of Endocrinology and Nutrition, Hospital del Mar, Paseo Mar\u00edtimo, 25-29, E-08003, Barcelona, Spain", 
            "Department of Medicine, Universitat Aut\u00f2noma de Barcelona, Campus Universitari Mar. Dr. Aiguader, 80, E-08003, Barcelona, Spain", 
            "Institut Hospital del Mar d\u2019Investigacions M\u00e8diques (IMIM), Dr. Aiguader, 80, E-08003, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chillar\u00f3n", 
        "givenName": "Juan J.", 
        "id": "sg:person.01307726754.87", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01307726754.87"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "CiberOBN. Instituto de Salud Carlos III, Avenida Monforte de Lemos, 3-5. Pabell\u00f3n 11. Planta 0, E-28029, Madrid, Spain", 
          "id": "http://www.grid.ac/institutes/grid.413448.e", 
          "name": [
            "Department of Endocrinology and Nutrition, Hospital del Mar, Paseo Mar\u00edtimo, 25-29, E-08003, Barcelona, Spain", 
            "Department of Medicine, Universitat Aut\u00f2noma de Barcelona, Campus Universitari Mar. Dr. Aiguader, 80, E-08003, Barcelona, Spain", 
            "Institut Hospital del Mar d\u2019Investigacions M\u00e8diques (IMIM), Dr. Aiguader, 80, E-08003, Barcelona, Spain", 
            "CiberOBN. Instituto de Salud Carlos III, Avenida Monforte de Lemos, 3-5. Pabell\u00f3n 11. Planta 0, E-28029, Madrid, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Goday", 
        "givenName": "Albert", 
        "id": "sg:person.0702754155.46", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0702754155.46"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/s11695-010-0279-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030467289", 
          "https://doi.org/10.1007/s11695-010-0279-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1381/096089291765560962", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048104866", 
          "https://doi.org/10.1381/096089291765560962"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00280883", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027902786", 
          "https://doi.org/10.1007/bf00280883"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11695-011-0534-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033471986", 
          "https://doi.org/10.1007/s11695-011-0534-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11695-012-0662-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015965218", 
          "https://doi.org/10.1007/s11695-012-0662-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11695-008-9547-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052048158", 
          "https://doi.org/10.1007/s11695-008-9547-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11695-015-1829-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039992961", 
          "https://doi.org/10.1007/s11695-015-1829-x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11695-015-1645-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008599008", 
          "https://doi.org/10.1007/s11695-015-1645-3"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2016-12-17", 
    "datePublishedReg": "2016-12-17", 
    "description": "PurposeGiven the lack of evidence of the effect of bariatric surgery (BS) on atherogenic dyslipidemia (AD), which is a characteristic of obese subjects, this study aimed to describe the remission rate of AD 1\u00a0year after BS in severely obese patients.Materials and MethodsA non-randomised, prospective cohort study was conducted in patients undergoing laparoscopic Roux-en-Y gastric bypass or laparoscopic sleeve gastrectomy with a 1-year follow-up. AD was defined as triglycerides \u22651.71\u00a0mmol/l or treatment with fibrates and low high-density lipoprotein (HDL) cholesterol (<1.03\u00a0mmol/l in men or <1.3\u00a0mmol/l in women).ResultsAD was present in 81 (22.8%) of the 356 patients; these were more frequently men and presented higher total cholesterol and non-HDL cholesterol concentrations. AD remission rate was 74.1% at 3\u00a0months, 90.1% at 6\u00a0months and 96.3% at 12\u00a0months, respectively, after BS. In this group of patients, HDL cholesterol levels rose progressively (1.0\u00a0\u00b1\u00a00.2 to 1.5\u00a0\u00b1\u00a00.3\u00a0mmol/l, p\u00a0<\u00a00.001) and triglycerides decreased (2.5\u00a0\u00b1\u00a00.9 to 1.2\u00a0\u00b1\u00a00.5\u00a0mmol/l, p\u00a0<\u00a00.001) during follow-up. Regarding previous lipid-lowering therapy, fibrates and ezetimibe were withdrawn in all patients and statins in 69.4% 1\u00a0year after surgery.ConclusionBS has beneficial effects on lipid profile, achieving complete remission of AD at 1\u00a0year of follow-up in almost all patients.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/s11695-016-2504-6", 
    "inLanguage": "en", 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1101268", 
        "issn": [
          "0960-8923", 
          "1708-0428"
        ], 
        "name": "Obesity Surgery", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "6", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "27"
      }
    ], 
    "keywords": [
      "bariatric surgery", 
      "atherogenic dyslipidemia", 
      "remission rate", 
      "low high-density lipoprotein cholesterol", 
      "previous lipid-lowering therapy", 
      "high-density lipoprotein cholesterol", 
      "non-HDL cholesterol concentrations", 
      "lipid-lowering therapy", 
      "prospective cohort study", 
      "laparoscopic sleeve gastrectomy", 
      "higher total cholesterol", 
      "remission 1 year", 
      "group of patients", 
      "HDL cholesterol levels", 
      "laparoscopic Roux", 
      "gastric bypass", 
      "sleeve gastrectomy", 
      "complete remission", 
      "obese patients", 
      "cohort study", 
      "lipoprotein cholesterol", 
      "lack of evidence", 
      "obese subjects", 
      "total cholesterol", 
      "cholesterol levels", 
      "lipid profile", 
      "cholesterol concentrations", 
      "patients", 
      "surgery", 
      "beneficial effects", 
      "months", 
      "fibrates", 
      "triglycerides", 
      "cholesterol", 
      "years", 
      "dyslipidemia", 
      "gastrectomy", 
      "remission", 
      "Roux", 
      "statins", 
      "bypass", 
      "therapy", 
      "ezetimibe", 
      "men", 
      "treatment", 
      "study", 
      "subjects", 
      "rate", 
      "effect", 
      "group", 
      "evidence", 
      "levels", 
      "AD 1", 
      "lack", 
      "concentration", 
      "profile", 
      "characteristics", 
      "materials", 
      "ResultsAD", 
      "AD remission rate", 
      "ConclusionBS", 
      "Atherogenic Dyslipidemia Remission 1 Year", 
      "Dyslipidemia Remission 1 Year"
    ], 
    "name": "Atherogenic Dyslipidemia Remission 1 Year After Bariatric Surgery", 
    "pagination": "1548-1553", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1009493666"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s11695-016-2504-6"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "27988827"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s11695-016-2504-6", 
      "https://app.dimensions.ai/details/publication/pub.1009493666"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2021-11-01T18:28", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20211101/entities/gbq_results/article/article_700.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/s11695-016-2504-6"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s11695-016-2504-6'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s11695-016-2504-6'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s11695-016-2504-6'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s11695-016-2504-6'


 

This table displays all metadata directly associated to this object as RDF triples.

287 TRIPLES      22 PREDICATES      111 URIs      95 LITERALS      21 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s11695-016-2504-6 schema:about N0a9b72b9877c4953ab809dd21401bad2
2 N0e69ce47f9864f52affe22c9fbfd42d1
3 N1f5defa619874f7c992af285ba68af47
4 N23ea17b677ae43a2ad767d085eb44bc4
5 N451b07db7655430c96dbdef24c97084d
6 N59c7eca1c9134b35b26e5f124f4f5190
7 N5a2184148ad34e1e8ab316e45dc31adb
8 N5cb8f692d2da4e0e9211c097993999dd
9 N5fb6370aa397419a8f2ba5aa33ef5cfc
10 N8651e18753a3497399942743df4432c5
11 Nbbb1696c46e2443fbaed2fac167c947a
12 Nde311aaa1d274b3aab48a74d4b1c9781
13 Nde84a10062d844ae86e6b98f9bab7ce6
14 Nfd23250e772e4a21b0fa750651772af4
15 anzsrc-for:11
16 anzsrc-for:1103
17 schema:author Ne32f9b5162804697be0a6be69939ed08
18 schema:citation sg:pub.10.1007/bf00280883
19 sg:pub.10.1007/s11695-008-9547-2
20 sg:pub.10.1007/s11695-010-0279-8
21 sg:pub.10.1007/s11695-011-0534-7
22 sg:pub.10.1007/s11695-012-0662-8
23 sg:pub.10.1007/s11695-015-1645-3
24 sg:pub.10.1007/s11695-015-1829-x
25 sg:pub.10.1381/096089291765560962
26 schema:datePublished 2016-12-17
27 schema:datePublishedReg 2016-12-17
28 schema:description PurposeGiven the lack of evidence of the effect of bariatric surgery (BS) on atherogenic dyslipidemia (AD), which is a characteristic of obese subjects, this study aimed to describe the remission rate of AD 1 year after BS in severely obese patients.Materials and MethodsA non-randomised, prospective cohort study was conducted in patients undergoing laparoscopic Roux-en-Y gastric bypass or laparoscopic sleeve gastrectomy with a 1-year follow-up. AD was defined as triglycerides ≥1.71 mmol/l or treatment with fibrates and low high-density lipoprotein (HDL) cholesterol (<1.03 mmol/l in men or <1.3 mmol/l in women).ResultsAD was present in 81 (22.8%) of the 356 patients; these were more frequently men and presented higher total cholesterol and non-HDL cholesterol concentrations. AD remission rate was 74.1% at 3 months, 90.1% at 6 months and 96.3% at 12 months, respectively, after BS. In this group of patients, HDL cholesterol levels rose progressively (1.0 ± 0.2 to 1.5 ± 0.3 mmol/l, p < 0.001) and triglycerides decreased (2.5 ± 0.9 to 1.2 ± 0.5 mmol/l, p < 0.001) during follow-up. Regarding previous lipid-lowering therapy, fibrates and ezetimibe were withdrawn in all patients and statins in 69.4% 1 year after surgery.ConclusionBS has beneficial effects on lipid profile, achieving complete remission of AD at 1 year of follow-up in almost all patients.
29 schema:genre article
30 schema:inLanguage en
31 schema:isAccessibleForFree true
32 schema:isPartOf N64773956c2fd497a87cef8843c084b23
33 Na69a22f9e0b141159236a447c1ca9e92
34 sg:journal.1101268
35 schema:keywords AD 1
36 AD remission rate
37 Atherogenic Dyslipidemia Remission 1 Year
38 ConclusionBS
39 Dyslipidemia Remission 1 Year
40 HDL cholesterol levels
41 ResultsAD
42 Roux
43 atherogenic dyslipidemia
44 bariatric surgery
45 beneficial effects
46 bypass
47 characteristics
48 cholesterol
49 cholesterol concentrations
50 cholesterol levels
51 cohort study
52 complete remission
53 concentration
54 dyslipidemia
55 effect
56 evidence
57 ezetimibe
58 fibrates
59 gastrectomy
60 gastric bypass
61 group
62 group of patients
63 high-density lipoprotein cholesterol
64 higher total cholesterol
65 lack
66 lack of evidence
67 laparoscopic Roux
68 laparoscopic sleeve gastrectomy
69 levels
70 lipid profile
71 lipid-lowering therapy
72 lipoprotein cholesterol
73 low high-density lipoprotein cholesterol
74 materials
75 men
76 months
77 non-HDL cholesterol concentrations
78 obese patients
79 obese subjects
80 patients
81 previous lipid-lowering therapy
82 profile
83 prospective cohort study
84 rate
85 remission
86 remission 1 year
87 remission rate
88 sleeve gastrectomy
89 statins
90 study
91 subjects
92 surgery
93 therapy
94 total cholesterol
95 treatment
96 triglycerides
97 years
98 schema:name Atherogenic Dyslipidemia Remission 1 Year After Bariatric Surgery
99 schema:pagination 1548-1553
100 schema:productId N738bc483e2d1406a837a24465dd89373
101 N8dbeb874b8a84d3eb58b586361cb39d8
102 N8dfa5c2f0a964891b91355b8f297f6c1
103 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009493666
104 https://doi.org/10.1007/s11695-016-2504-6
105 schema:sdDatePublished 2021-11-01T18:28
106 schema:sdLicense https://scigraph.springernature.com/explorer/license/
107 schema:sdPublisher N313d796e090d4fb7bc8405ba1743dccd
108 schema:url https://doi.org/10.1007/s11695-016-2504-6
109 sgo:license sg:explorer/license/
110 sgo:sdDataset articles
111 rdf:type schema:ScholarlyArticle
112 N0a9b72b9877c4953ab809dd21401bad2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
113 schema:name Adult
114 rdf:type schema:DefinedTerm
115 N0c8b371159d24e259df0a423607db21d rdf:first sg:person.01301600460.81
116 rdf:rest N90734f3d60104df086ea24f6874feb63
117 N0e69ce47f9864f52affe22c9fbfd42d1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
118 schema:name Remission Induction
119 rdf:type schema:DefinedTerm
120 N1f5defa619874f7c992af285ba68af47 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
121 schema:name Triglycerides
122 rdf:type schema:DefinedTerm
123 N23ea17b677ae43a2ad767d085eb44bc4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
124 schema:name Dyslipidemias
125 rdf:type schema:DefinedTerm
126 N313d796e090d4fb7bc8405ba1743dccd schema:name Springer Nature - SN SciGraph project
127 rdf:type schema:Organization
128 N451b07db7655430c96dbdef24c97084d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
129 schema:name Male
130 rdf:type schema:DefinedTerm
131 N52ff546d3564410e9fa587ea446e0a51 rdf:first sg:person.01312131655.72
132 rdf:rest Nf0560f6de87e41909a3a09e78fe46b01
133 N59c7eca1c9134b35b26e5f124f4f5190 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
134 schema:name Middle Aged
135 rdf:type schema:DefinedTerm
136 N5a2184148ad34e1e8ab316e45dc31adb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
137 schema:name Prospective Studies
138 rdf:type schema:DefinedTerm
139 N5cb8f692d2da4e0e9211c097993999dd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
140 schema:name Weight Loss
141 rdf:type schema:DefinedTerm
142 N5fb6370aa397419a8f2ba5aa33ef5cfc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
143 schema:name Obesity, Morbid
144 rdf:type schema:DefinedTerm
145 N64773956c2fd497a87cef8843c084b23 schema:volumeNumber 27
146 rdf:type schema:PublicationVolume
147 N738bc483e2d1406a837a24465dd89373 schema:name dimensions_id
148 schema:value pub.1009493666
149 rdf:type schema:PropertyValue
150 N84785b43171d4b16941b09485b23f54c rdf:first sg:person.016161272315.22
151 rdf:rest N9c643a33e05842e0af4c4d5e68e5f544
152 N8651e18753a3497399942743df4432c5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
153 schema:name Atherosclerosis
154 rdf:type schema:DefinedTerm
155 N8dbeb874b8a84d3eb58b586361cb39d8 schema:name doi
156 schema:value 10.1007/s11695-016-2504-6
157 rdf:type schema:PropertyValue
158 N8dfa5c2f0a964891b91355b8f297f6c1 schema:name pubmed_id
159 schema:value 27988827
160 rdf:type schema:PropertyValue
161 N90734f3d60104df086ea24f6874feb63 rdf:first sg:person.01235473723.90
162 rdf:rest N52ff546d3564410e9fa587ea446e0a51
163 N9c643a33e05842e0af4c4d5e68e5f544 rdf:first sg:person.01307726754.87
164 rdf:rest Nd27e155561c147609298a9990193480f
165 Na69a22f9e0b141159236a447c1ca9e92 schema:issueNumber 6
166 rdf:type schema:PublicationIssue
167 Nbbb1696c46e2443fbaed2fac167c947a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
168 schema:name Gastric Bypass
169 rdf:type schema:DefinedTerm
170 Nd27e155561c147609298a9990193480f rdf:first sg:person.0702754155.46
171 rdf:rest rdf:nil
172 Nde311aaa1d274b3aab48a74d4b1c9781 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
173 schema:name Gastrectomy
174 rdf:type schema:DefinedTerm
175 Nde84a10062d844ae86e6b98f9bab7ce6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
176 schema:name Humans
177 rdf:type schema:DefinedTerm
178 Ne32f9b5162804697be0a6be69939ed08 rdf:first sg:person.01173213347.44
179 rdf:rest Necf58acdc06146c8b45b7bd6ef0c7112
180 Necf58acdc06146c8b45b7bd6ef0c7112 rdf:first sg:person.01173500354.32
181 rdf:rest N0c8b371159d24e259df0a423607db21d
182 Nf0560f6de87e41909a3a09e78fe46b01 rdf:first sg:person.0771055147.50
183 rdf:rest N84785b43171d4b16941b09485b23f54c
184 Nfd23250e772e4a21b0fa750651772af4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
185 schema:name Female
186 rdf:type schema:DefinedTerm
187 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
188 schema:name Medical and Health Sciences
189 rdf:type schema:DefinedTerm
190 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
191 schema:name Clinical Sciences
192 rdf:type schema:DefinedTerm
193 sg:journal.1101268 schema:issn 0960-8923
194 1708-0428
195 schema:name Obesity Surgery
196 schema:publisher Springer Nature
197 rdf:type schema:Periodical
198 sg:person.01173213347.44 schema:affiliation grid-institutes:grid.7080.f
199 schema:familyName Climent
200 schema:givenName Elisenda
201 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01173213347.44
202 rdf:type schema:Person
203 sg:person.01173500354.32 schema:affiliation grid-institutes:grid.20522.37
204 schema:familyName Benaiges
205 schema:givenName David
206 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01173500354.32
207 rdf:type schema:Person
208 sg:person.01235473723.90 schema:affiliation grid-institutes:grid.20522.37
209 schema:familyName Flores-Le Roux
210 schema:givenName Juana A.
211 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01235473723.90
212 rdf:type schema:Person
213 sg:person.01301600460.81 schema:affiliation grid-institutes:grid.20522.37
214 schema:familyName Pedro-Botet
215 schema:givenName Juan
216 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01301600460.81
217 rdf:type schema:Person
218 sg:person.01307726754.87 schema:affiliation grid-institutes:grid.20522.37
219 schema:familyName Chillarón
220 schema:givenName Juan J.
221 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01307726754.87
222 rdf:type schema:Person
223 sg:person.01312131655.72 schema:affiliation grid-institutes:grid.411142.3
224 schema:familyName Ramón
225 schema:givenName Jose M.
226 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01312131655.72
227 rdf:type schema:Person
228 sg:person.016161272315.22 schema:affiliation grid-institutes:grid.411142.3
229 schema:familyName Fontané
230 schema:givenName Laia
231 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016161272315.22
232 rdf:type schema:Person
233 sg:person.0702754155.46 schema:affiliation grid-institutes:grid.413448.e
234 schema:familyName Goday
235 schema:givenName Albert
236 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0702754155.46
237 rdf:type schema:Person
238 sg:person.0771055147.50 schema:affiliation grid-institutes:grid.411142.3
239 schema:familyName Villatoro
240 schema:givenName Montserrat
241 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0771055147.50
242 rdf:type schema:Person
243 sg:pub.10.1007/bf00280883 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027902786
244 https://doi.org/10.1007/bf00280883
245 rdf:type schema:CreativeWork
246 sg:pub.10.1007/s11695-008-9547-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052048158
247 https://doi.org/10.1007/s11695-008-9547-2
248 rdf:type schema:CreativeWork
249 sg:pub.10.1007/s11695-010-0279-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030467289
250 https://doi.org/10.1007/s11695-010-0279-8
251 rdf:type schema:CreativeWork
252 sg:pub.10.1007/s11695-011-0534-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033471986
253 https://doi.org/10.1007/s11695-011-0534-7
254 rdf:type schema:CreativeWork
255 sg:pub.10.1007/s11695-012-0662-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015965218
256 https://doi.org/10.1007/s11695-012-0662-8
257 rdf:type schema:CreativeWork
258 sg:pub.10.1007/s11695-015-1645-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008599008
259 https://doi.org/10.1007/s11695-015-1645-3
260 rdf:type schema:CreativeWork
261 sg:pub.10.1007/s11695-015-1829-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1039992961
262 https://doi.org/10.1007/s11695-015-1829-x
263 rdf:type schema:CreativeWork
264 sg:pub.10.1381/096089291765560962 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048104866
265 https://doi.org/10.1381/096089291765560962
266 rdf:type schema:CreativeWork
267 grid-institutes:grid.20522.37 schema:alternateName Institut Hospital del Mar d’Investigacions Mèdiques (IMIM), Dr. Aiguader, 80, E-08003, Barcelona, Spain
268 schema:name Department of Endocrinology and Nutrition, Hospital del Mar, Paseo Marítimo, 25-29, E-08003, Barcelona, Spain
269 Department of Medicine, Universitat Autònoma de Barcelona, Campus Universitari Mar. Dr. Aiguader, 80, E-08003, Barcelona, Spain
270 Institut Hospital del Mar d’Investigacions Mèdiques (IMIM), Dr. Aiguader, 80, E-08003, Barcelona, Spain
271 rdf:type schema:Organization
272 grid-institutes:grid.411142.3 schema:alternateName Department of Endocrinology and Nutrition, Hospital del Mar, Paseo Marítimo, 25-29, E-08003, Barcelona, Spain
273 Department of General Surgery, Hospital del Mar, Paseo Marítimo, 25-29, E-08003, Barcelona, Spain
274 schema:name Department of Endocrinology and Nutrition, Hospital del Mar, Paseo Marítimo, 25-29, E-08003, Barcelona, Spain
275 Department of General Surgery, Hospital del Mar, Paseo Marítimo, 25-29, E-08003, Barcelona, Spain
276 Institut Hospital del Mar d’Investigacions Mèdiques (IMIM), Dr. Aiguader, 80, E-08003, Barcelona, Spain
277 rdf:type schema:Organization
278 grid-institutes:grid.413448.e schema:alternateName CiberOBN. Instituto de Salud Carlos III, Avenida Monforte de Lemos, 3-5. Pabellón 11. Planta 0, E-28029, Madrid, Spain
279 schema:name CiberOBN. Instituto de Salud Carlos III, Avenida Monforte de Lemos, 3-5. Pabellón 11. Planta 0, E-28029, Madrid, Spain
280 Department of Endocrinology and Nutrition, Hospital del Mar, Paseo Marítimo, 25-29, E-08003, Barcelona, Spain
281 Department of Medicine, Universitat Autònoma de Barcelona, Campus Universitari Mar. Dr. Aiguader, 80, E-08003, Barcelona, Spain
282 Institut Hospital del Mar d’Investigacions Mèdiques (IMIM), Dr. Aiguader, 80, E-08003, Barcelona, Spain
283 rdf:type schema:Organization
284 grid-institutes:grid.7080.f schema:alternateName Department of Medicine, Universitat Autònoma de Barcelona, Campus Universitari Mar. Dr. Aiguader, 80, E-08003, Barcelona, Spain
285 schema:name Department of Endocrinology and Nutrition, Hospital del Mar, Paseo Marítimo, 25-29, E-08003, Barcelona, Spain
286 Department of Medicine, Universitat Autònoma de Barcelona, Campus Universitari Mar. Dr. Aiguader, 80, E-08003, Barcelona, Spain
287 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...