Ontology type: schema:ScholarlyArticle
2017-04
AUTHORSB. Coffin, V. Maunoury, F. Pattou, X. Hébuterne, S. Schneider, M. Coupaye, S. Ledoux, F. Iglicki, F. Mion, M. Robert, E. Disse, J. Escourrou, G. Tuyeras, Y. Le Roux, C. Arvieux, P. Pouderoux, N. Huten, T. Alfaiate, D. Hajage, S. Msika
ABSTRACTBACKGROUND: Super obese patients are recommended to lose weight before bariatric surgery. The effect of intragastric balloon (IGB)-induced weight loss before laparoscopic gastric bypass (LGBP) has not been reported. The aim of this prospective randomized multicenter study was to compare the impact of preoperative 6-month IGB with standard medical care (SMC) in LGBP patients. METHODS: Patients with BMI >45 kg/m2 selected for LGBP were included and randomized to receive either SMC or IGB. After 6 months (M6), the IGB was removed and LGBP was performed in both groups. Postoperative follow-up period was 6 months (M12). The primary endpoint was the proportion of patients requiring ICU stay >24 h; secondary criteria were weight changes, operative time, hospitalization stay, and perioperative complications. RESULTS: Only 115 patients were included (BMI 54.3 ± 8.7 kg/m2), of which 55 underwent IGB insertion. The proportion of patients who stayed in ICU >24 h was similar in both groups (P = 0.87). At M6, weight loss was significantly greater in the IGB group than in the SMC group (P < 0.0001). Three severe complications occurred during IGB removal. Mean operative time for LGBP was similar in both groups (P = 0.49). Five patients had 1 or more surgical complications, all in the IGB group (P = 0.02). Both groups had similar hospitalization stay (P = 0.59) and weight loss at M12 (P = 0.31). CONCLUSION: IGB insertion before LGBP induced weight loss but did not improve the perioperative outcomes or affect postoperative weight loss. More... »
PAGES902-909
http://scigraph.springernature.com/pub.10.1007/s11695-016-2383-x
DOIhttp://dx.doi.org/10.1007/s11695-016-2383-x
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1029588314
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/27664095
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"description": "BACKGROUND: Super obese patients are recommended to lose weight before bariatric surgery. The effect of intragastric balloon (IGB)-induced weight loss before laparoscopic gastric bypass (LGBP) has not been reported. The aim of this prospective randomized multicenter study was to compare the impact of preoperative 6-month IGB with standard medical care (SMC) in LGBP patients.\nMETHODS: Patients with BMI >45\u00a0kg/m2 selected for LGBP were included and randomized to receive either SMC or IGB. After 6\u00a0months (M6), the IGB was removed and LGBP was performed in both groups. Postoperative follow-up period was 6\u00a0months (M12). The primary endpoint was the proportion of patients requiring ICU stay >24\u00a0h; secondary criteria were weight changes, operative time, hospitalization stay, and perioperative complications.\nRESULTS: Only 115 patients were included (BMI 54.3\u00a0\u00b1\u00a08.7\u00a0kg/m2), of which 55 underwent IGB insertion. The proportion of patients who stayed in ICU >24\u00a0h was similar in both groups (P\u00a0=\u00a00.87). At M6, weight loss was significantly greater in the IGB group than in the SMC group (P\u00a0<\u00a00.0001). Three severe complications occurred during IGB removal. Mean operative time for LGBP was similar in both groups (P\u00a0=\u00a00.49). Five patients had 1 or more surgical complications, all in the IGB group (P\u00a0=\u00a00.02). Both groups had similar hospitalization stay (P\u00a0=\u00a00.59) and weight loss at M12 (P\u00a0=\u00a00.31).\nCONCLUSION: IGB insertion before LGBP induced weight loss but did not improve the perioperative outcomes or affect postoperative weight loss.",
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