Chronic Renin–Angiotensin System (RAS) Blockade May Not Induce Hypotension During Anaesthesia for Bariatric Surgery View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2016-06

AUTHORS

Guido Salvetti, Claudio Di Salvo, Giovanni Ceccarini, Antonio Abramo, Paola Fierabracci, Silvia Magno, Paolo Piaggi, Paolo Vitti, Ferruccio Santini

ABSTRACT

The use of angiotensin-converting enzyme inhibitors (ACE-I) and angiotensin II receptor blockers (ARB) for the treatment of hypertensive obese patients is steadily increasing. Some studies have reported that the use of these drugs was associated with an increased risk of hypotensive episodes, during general anaesthesia. The number of bariatric procedures is also increasing worldwide, but there is a lack of studies investigating the hypotensive effect of renin-angiotensin system (RAS) blockers in severely obese patients during general anaesthesia for bariatric surgery. The aim of this pilot study was to evaluate hemodynamic changes induced by general anaesthesia in obese patients chronically treated with ACE-I or ARB compared to a control group not treated with antihypertensive therapy. Fourteen obese subjects (mean body mass index (BMI) 47.5 kg/m(2)) treated with ACE-I or ARB and twelve obese (mean BMI 45.7 kg/m2) controls not treated with antihypertensive therapy underwent general anaesthesia to perform laparoscopic bariatric surgery. Systolic blood pressure, diastolic blood pressure, and heart rate were monitored continuously and registered at different time points: T0 before induction, then at 2, 5, 7, 10, 15, 20, 30, 60, 90, 120, and 150 min after induction, and the last time point taken following recovery from anaesthesia. A progressive reduction of both systolic and diastolic blood pressure values was observed without significant differences between the two groups. A similar trend of heart rate values was observed. In conclusion, our pilot study suggests that RAS blockers may be continued during the perioperative period in patients undergoing bariatric surgery, without increasing the risk of hypotensive episodes. More... »

PAGES

1303-1307

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11695-015-1862-9

DOI

http://dx.doi.org/10.1007/s11695-015-1862-9

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1023680595

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/26328531


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Anesthesia, General", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Angiotensin II Type 1 Receptor Blockers", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Angiotensin-Converting Enzyme Inhibitors", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antihypertensive Agents", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Bariatric Surgery", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Blood Pressure", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Heart Rate", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hypertension", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hypotension", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Obesity, Morbid", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Perioperative Care", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Pilot Projects", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Renin-Angiotensin System", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "name": [
            "Obesity Centre at the Endocrinology Unit, University Hospital of Pisa, Via Paradisa, 2, 56124, Pisa, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Salvetti", 
        "givenName": "Guido", 
        "id": "sg:person.01313770306.19", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01313770306.19"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Unit of Anaesthesia and Reanimation in Obesity Surgery and Diseases of Upper Gut, University Hospital of Pisa, Via Paradisa, 2, 56124, Pisa, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Di Salvo", 
        "givenName": "Claudio", 
        "id": "sg:person.01266027765.01", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01266027765.01"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Obesity Centre at the Endocrinology Unit, University Hospital of Pisa, Via Paradisa, 2, 56124, Pisa, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ceccarini", 
        "givenName": "Giovanni", 
        "id": "sg:person.01171104613.28", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01171104613.28"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Unit of Anaesthesia and Reanimation in Obesity Surgery and Diseases of Upper Gut, University Hospital of Pisa, Via Paradisa, 2, 56124, Pisa, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Abramo", 
        "givenName": "Antonio", 
        "id": "sg:person.01217714565.04", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01217714565.04"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Obesity Centre at the Endocrinology Unit, University Hospital of Pisa, Via Paradisa, 2, 56124, Pisa, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fierabracci", 
        "givenName": "Paola", 
        "id": "sg:person.01302451207.28", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01302451207.28"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Obesity Centre at the Endocrinology Unit, University Hospital of Pisa, Via Paradisa, 2, 56124, Pisa, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Magno", 
        "givenName": "Silvia", 
        "id": "sg:person.01346066015.63", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01346066015.63"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Obesity Centre at the Endocrinology Unit, University Hospital of Pisa, Via Paradisa, 2, 56124, Pisa, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Piaggi", 
        "givenName": "Paolo", 
        "id": "sg:person.0614150407.49", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0614150407.49"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Obesity Centre at the Endocrinology Unit, University Hospital of Pisa, Via Paradisa, 2, 56124, Pisa, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Vitti", 
        "givenName": "Paolo", 
        "id": "sg:person.0777360014.47", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0777360014.47"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Obesity Centre at the Endocrinology Unit, University Hospital of Pisa, Via Paradisa, 2, 56124, Pisa, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Santini", 
        "givenName": "Ferruccio", 
        "id": "sg:person.01226525757.06", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01226525757.06"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1053/j.jvca.2007.12.020", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002178014"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/bja/86.1.90", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002651097"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1213/00000539-199301000-00005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002739971"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1381/096089200321643511", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007224499", 
          "https://doi.org/10.1381/096089200321643511"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1213/01.ane.0000146521.68059.a1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009559193"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1213/01.ane.0000146521.68059.a1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009559193"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1213/00000539-199912000-00011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009686404"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1213/00000539-199912000-00011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009686404"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/pgmj.2010.112987", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012962089"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/pgmj.2010.112987", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012962089"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0888-6296(89)97459-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013416812"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000542-200306000-00007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014094587"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000542-200306000-00007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014094587"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000542-200306000-00007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014094587"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11695-009-9973-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018986712", 
          "https://doi.org/10.1007/s11695-009-9973-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11695-009-9973-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018986712", 
          "https://doi.org/10.1007/s11695-009-9973-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/hjh.0b013e3283537347", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019176222"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/hjh.0b013e3283537347", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019176222"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/hjh.0b013e328010b8f3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021363163"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/hjh.0b013e328010b8f3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021363163"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1213/00000539-199911000-00012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023802879"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1213/00000539-199911000-00012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023802879"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1213/00000539-199911000-00012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023802879"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s13054-014-0644-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027369001", 
          "https://doi.org/10.1186/s13054-014-0644-4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s13054-014-0644-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027369001", 
          "https://doi.org/10.1186/s13054-014-0644-4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/j.jvca.2008.01.002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032122653"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000539-200101000-00006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033661937"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000539-200101000-00006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033661937"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/cc4896", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046631768", 
          "https://doi.org/10.1186/cc4896"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/cc4896", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046631768", 
          "https://doi.org/10.1186/cc4896"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1213/ane.0000000000000076", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051868231"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1213/ane.0000000000000076", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051868231"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000539-200204000-00011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052387552"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000539-200204000-00011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052387552"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2174/0929867311320100008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1069163082"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2174/1381612033455413", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1069165030"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1076813008", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2016-06", 
    "datePublishedReg": "2016-06-01", 
    "description": "The use of angiotensin-converting enzyme inhibitors (ACE-I) and angiotensin II receptor blockers (ARB) for the treatment of hypertensive obese patients is steadily increasing. Some studies have reported that the use of these drugs was associated with an increased risk of hypotensive episodes, during general anaesthesia. The number of bariatric procedures is also increasing worldwide, but there is a lack of studies investigating the hypotensive effect of renin-angiotensin system (RAS) blockers in severely obese patients during general anaesthesia for bariatric surgery. The aim of this pilot study was to evaluate hemodynamic changes induced by general anaesthesia in obese patients chronically treated with ACE-I or ARB compared to a control group not treated with antihypertensive therapy. Fourteen obese subjects (mean body mass index (BMI) 47.5\u00a0kg/m(2)) treated with ACE-I or ARB and twelve obese (mean BMI 45.7\u00a0kg/m2) controls not treated with antihypertensive therapy underwent general anaesthesia to perform laparoscopic bariatric surgery. Systolic blood pressure, diastolic blood pressure, and heart rate were monitored continuously and registered at different time points: T0 before induction, then at 2, 5, 7, 10, 15, 20, 30, 60, 90, 120, and 150\u00a0min after induction, and the last time point taken following recovery from anaesthesia. A progressive reduction of both systolic and diastolic blood pressure values was observed without significant differences between the two groups. A similar trend of heart rate values was observed. In conclusion, our pilot study suggests that RAS blockers may be continued during the perioperative period in patients undergoing bariatric surgery, without increasing the risk of hypotensive episodes.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s11695-015-1862-9", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1101268", 
        "issn": [
          "0960-8923", 
          "1708-0428"
        ], 
        "name": "Obesity Surgery", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "6", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "26"
      }
    ], 
    "name": "Chronic Renin\u2013Angiotensin System (RAS) Blockade May Not Induce Hypotension During Anaesthesia for Bariatric Surgery", 
    "pagination": "1303-1307", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "70d21b699167ea5942dbb148a3cbe0378cf4bccad50643fefa96d2890e518a54"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "26328531"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "9106714"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s11695-015-1862-9"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1023680595"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s11695-015-1862-9", 
      "https://app.dimensions.ai/details/publication/pub.1023680595"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T20:49", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8684_00000522.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007%2Fs11695-015-1862-9"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s11695-015-1862-9'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s11695-015-1862-9'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s11695-015-1862-9'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s11695-015-1862-9'


 

This table displays all metadata directly associated to this object as RDF triples.

281 TRIPLES      21 PREDICATES      69 URIs      39 LITERALS      27 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s11695-015-1862-9 schema:about N05273224f16a456b91f145fe97ce25c0
2 N063b082a1135449980d90143ef654e8f
3 N1a7dd38e7c464d709179147f1a1022b1
4 N1b8e8989b4534fcb9327fb2e6bb6b8d6
5 N1e13d7b9077a46da97fe7a2c5c277e2e
6 N2a36d40026594e23a74eb3c169c44996
7 N374f0aa795b74ca09df16c49f3571e00
8 N42af8b6f0bd04222b7cdc882b6b5a79d
9 N4a09e67125444a5882a9e8459da19c45
10 N4dd17c0009524a9b9d9205a145cbc6b2
11 N72122cd2440d4610a218a6a72f6e2632
12 N8a0ce3716e2e47f68fd5f2f11fd49a86
13 Nabf80c7cfd564827aa27a296b061b920
14 Nc64023705cf34ff79eb41d1b594820b0
15 Ncff4f6a8ad664fd494876413708b18ab
16 Nd8d8ad0358e74675bf7e0cdc342b2acd
17 Nf3a8445c3b7641ecbf5c07b12199f47c
18 Nff9ed82aed9c4166be36cff0f947350a
19 anzsrc-for:11
20 anzsrc-for:1103
21 schema:author N0aac7cba94464e27904a9e6133b3fc00
22 schema:citation sg:pub.10.1007/s11695-009-9973-9
23 sg:pub.10.1186/cc4896
24 sg:pub.10.1186/s13054-014-0644-4
25 sg:pub.10.1381/096089200321643511
26 https://app.dimensions.ai/details/publication/pub.1076813008
27 https://doi.org/10.1016/s0888-6296(89)97459-0
28 https://doi.org/10.1053/j.jvca.2007.12.020
29 https://doi.org/10.1053/j.jvca.2008.01.002
30 https://doi.org/10.1093/bja/86.1.90
31 https://doi.org/10.1097/00000539-200101000-00006
32 https://doi.org/10.1097/00000539-200204000-00011
33 https://doi.org/10.1097/00000542-200306000-00007
34 https://doi.org/10.1097/hjh.0b013e328010b8f3
35 https://doi.org/10.1097/hjh.0b013e3283537347
36 https://doi.org/10.1136/pgmj.2010.112987
37 https://doi.org/10.1213/00000539-199301000-00005
38 https://doi.org/10.1213/00000539-199911000-00012
39 https://doi.org/10.1213/00000539-199912000-00011
40 https://doi.org/10.1213/01.ane.0000146521.68059.a1
41 https://doi.org/10.1213/ane.0000000000000076
42 https://doi.org/10.2174/0929867311320100008
43 https://doi.org/10.2174/1381612033455413
44 schema:datePublished 2016-06
45 schema:datePublishedReg 2016-06-01
46 schema:description The use of angiotensin-converting enzyme inhibitors (ACE-I) and angiotensin II receptor blockers (ARB) for the treatment of hypertensive obese patients is steadily increasing. Some studies have reported that the use of these drugs was associated with an increased risk of hypotensive episodes, during general anaesthesia. The number of bariatric procedures is also increasing worldwide, but there is a lack of studies investigating the hypotensive effect of renin-angiotensin system (RAS) blockers in severely obese patients during general anaesthesia for bariatric surgery. The aim of this pilot study was to evaluate hemodynamic changes induced by general anaesthesia in obese patients chronically treated with ACE-I or ARB compared to a control group not treated with antihypertensive therapy. Fourteen obese subjects (mean body mass index (BMI) 47.5 kg/m(2)) treated with ACE-I or ARB and twelve obese (mean BMI 45.7 kg/m2) controls not treated with antihypertensive therapy underwent general anaesthesia to perform laparoscopic bariatric surgery. Systolic blood pressure, diastolic blood pressure, and heart rate were monitored continuously and registered at different time points: T0 before induction, then at 2, 5, 7, 10, 15, 20, 30, 60, 90, 120, and 150 min after induction, and the last time point taken following recovery from anaesthesia. A progressive reduction of both systolic and diastolic blood pressure values was observed without significant differences between the two groups. A similar trend of heart rate values was observed. In conclusion, our pilot study suggests that RAS blockers may be continued during the perioperative period in patients undergoing bariatric surgery, without increasing the risk of hypotensive episodes.
47 schema:genre research_article
48 schema:inLanguage en
49 schema:isAccessibleForFree false
50 schema:isPartOf Nbc8ac2f475514d8f84edfca025c6ff36
51 Nf74b9abd03b44055beb6155bc5bc28fc
52 sg:journal.1101268
53 schema:name Chronic Renin–Angiotensin System (RAS) Blockade May Not Induce Hypotension During Anaesthesia for Bariatric Surgery
54 schema:pagination 1303-1307
55 schema:productId N11de009106c84b359bee1abc55a7753a
56 N4b54cf48c32740db8a5af6ae37fbec57
57 N6229481f253c4761be76f2d121c09a6f
58 Na3dc4db5239b404d8645a244cc52883c
59 Ncff77a67615842259ecc5fe2c39c4fb8
60 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023680595
61 https://doi.org/10.1007/s11695-015-1862-9
62 schema:sdDatePublished 2019-04-10T20:49
63 schema:sdLicense https://scigraph.springernature.com/explorer/license/
64 schema:sdPublisher N6172dfa96e1d441bb50654e1424d3794
65 schema:url http://link.springer.com/10.1007%2Fs11695-015-1862-9
66 sgo:license sg:explorer/license/
67 sgo:sdDataset articles
68 rdf:type schema:ScholarlyArticle
69 N00be7b038eea47938709619c29e0f835 schema:name Unit of Anaesthesia and Reanimation in Obesity Surgery and Diseases of Upper Gut, University Hospital of Pisa, Via Paradisa, 2, 56124, Pisa, Italy
70 rdf:type schema:Organization
71 N05273224f16a456b91f145fe97ce25c0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
72 schema:name Pilot Projects
73 rdf:type schema:DefinedTerm
74 N063b082a1135449980d90143ef654e8f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
75 schema:name Hypotension
76 rdf:type schema:DefinedTerm
77 N0aac7cba94464e27904a9e6133b3fc00 rdf:first sg:person.01313770306.19
78 rdf:rest N255d153295914cffae2fa42d501a4f46
79 N0f01833858c24935a24ee84144f129d8 rdf:first sg:person.01346066015.63
80 rdf:rest N3a0c90337ef346d2960c29900965b390
81 N11de009106c84b359bee1abc55a7753a schema:name pubmed_id
82 schema:value 26328531
83 rdf:type schema:PropertyValue
84 N1a7dd38e7c464d709179147f1a1022b1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
85 schema:name Female
86 rdf:type schema:DefinedTerm
87 N1b8e8989b4534fcb9327fb2e6bb6b8d6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
88 schema:name Heart Rate
89 rdf:type schema:DefinedTerm
90 N1e13d7b9077a46da97fe7a2c5c277e2e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
91 schema:name Anesthesia, General
92 rdf:type schema:DefinedTerm
93 N242fe039ec124bb4a850b8c5b67f8b6a schema:name Obesity Centre at the Endocrinology Unit, University Hospital of Pisa, Via Paradisa, 2, 56124, Pisa, Italy
94 rdf:type schema:Organization
95 N255d153295914cffae2fa42d501a4f46 rdf:first sg:person.01266027765.01
96 rdf:rest N706e9076906840d79da911bf57ea18c8
97 N2a36d40026594e23a74eb3c169c44996 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
98 schema:name Angiotensin-Converting Enzyme Inhibitors
99 rdf:type schema:DefinedTerm
100 N374f0aa795b74ca09df16c49f3571e00 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
101 schema:name Male
102 rdf:type schema:DefinedTerm
103 N3a0c90337ef346d2960c29900965b390 rdf:first sg:person.0614150407.49
104 rdf:rest N979440d0a7454d0fa01bccc467030b0b
105 N42af8b6f0bd04222b7cdc882b6b5a79d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
106 schema:name Hypertension
107 rdf:type schema:DefinedTerm
108 N44987abc12e041429c94c6e9050bab41 schema:name Unit of Anaesthesia and Reanimation in Obesity Surgery and Diseases of Upper Gut, University Hospital of Pisa, Via Paradisa, 2, 56124, Pisa, Italy
109 rdf:type schema:Organization
110 N4a09e67125444a5882a9e8459da19c45 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
111 schema:name Humans
112 rdf:type schema:DefinedTerm
113 N4ae73ac41b3442ed92ebd5ff3fc410c4 schema:name Obesity Centre at the Endocrinology Unit, University Hospital of Pisa, Via Paradisa, 2, 56124, Pisa, Italy
114 rdf:type schema:Organization
115 N4b54cf48c32740db8a5af6ae37fbec57 schema:name dimensions_id
116 schema:value pub.1023680595
117 rdf:type schema:PropertyValue
118 N4dd17c0009524a9b9d9205a145cbc6b2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
119 schema:name Antihypertensive Agents
120 rdf:type schema:DefinedTerm
121 N5c23c9553b7a45b487cb1b189eafec30 rdf:first sg:person.01217714565.04
122 rdf:rest N7f482b19161d4404a288ebd8848e28af
123 N6172dfa96e1d441bb50654e1424d3794 schema:name Springer Nature - SN SciGraph project
124 rdf:type schema:Organization
125 N6229481f253c4761be76f2d121c09a6f schema:name readcube_id
126 schema:value 70d21b699167ea5942dbb148a3cbe0378cf4bccad50643fefa96d2890e518a54
127 rdf:type schema:PropertyValue
128 N64fe5c584da3465a8c5b22e62def9a56 schema:name Obesity Centre at the Endocrinology Unit, University Hospital of Pisa, Via Paradisa, 2, 56124, Pisa, Italy
129 rdf:type schema:Organization
130 N68515ec5a21f4061bff90e175669153b schema:name Obesity Centre at the Endocrinology Unit, University Hospital of Pisa, Via Paradisa, 2, 56124, Pisa, Italy
131 rdf:type schema:Organization
132 N706e9076906840d79da911bf57ea18c8 rdf:first sg:person.01171104613.28
133 rdf:rest N5c23c9553b7a45b487cb1b189eafec30
134 N72122cd2440d4610a218a6a72f6e2632 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
135 schema:name Adult
136 rdf:type schema:DefinedTerm
137 N735e2530d2c44bebb5d03c2b449699e7 schema:name Obesity Centre at the Endocrinology Unit, University Hospital of Pisa, Via Paradisa, 2, 56124, Pisa, Italy
138 rdf:type schema:Organization
139 N7f482b19161d4404a288ebd8848e28af rdf:first sg:person.01302451207.28
140 rdf:rest N0f01833858c24935a24ee84144f129d8
141 N8a0ce3716e2e47f68fd5f2f11fd49a86 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
142 schema:name Obesity, Morbid
143 rdf:type schema:DefinedTerm
144 N979440d0a7454d0fa01bccc467030b0b rdf:first sg:person.0777360014.47
145 rdf:rest Na5eae7b2c95e4af7a6b319a444bb6145
146 Na3dc4db5239b404d8645a244cc52883c schema:name doi
147 schema:value 10.1007/s11695-015-1862-9
148 rdf:type schema:PropertyValue
149 Na5eae7b2c95e4af7a6b319a444bb6145 rdf:first sg:person.01226525757.06
150 rdf:rest rdf:nil
151 Nabdeba95999343bda58c1c824ecfdd11 schema:name Obesity Centre at the Endocrinology Unit, University Hospital of Pisa, Via Paradisa, 2, 56124, Pisa, Italy
152 rdf:type schema:Organization
153 Nabf80c7cfd564827aa27a296b061b920 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
154 schema:name Bariatric Surgery
155 rdf:type schema:DefinedTerm
156 Nbc8ac2f475514d8f84edfca025c6ff36 schema:volumeNumber 26
157 rdf:type schema:PublicationVolume
158 Nc64023705cf34ff79eb41d1b594820b0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
159 schema:name Angiotensin II Type 1 Receptor Blockers
160 rdf:type schema:DefinedTerm
161 Ncff4f6a8ad664fd494876413708b18ab schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
162 schema:name Blood Pressure
163 rdf:type schema:DefinedTerm
164 Ncff77a67615842259ecc5fe2c39c4fb8 schema:name nlm_unique_id
165 schema:value 9106714
166 rdf:type schema:PropertyValue
167 Nd8d8ad0358e74675bf7e0cdc342b2acd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
168 schema:name Middle Aged
169 rdf:type schema:DefinedTerm
170 Ne3ff0067df6343c1953d2fe58704f6bb schema:name Obesity Centre at the Endocrinology Unit, University Hospital of Pisa, Via Paradisa, 2, 56124, Pisa, Italy
171 rdf:type schema:Organization
172 Nf3a8445c3b7641ecbf5c07b12199f47c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
173 schema:name Perioperative Care
174 rdf:type schema:DefinedTerm
175 Nf74b9abd03b44055beb6155bc5bc28fc schema:issueNumber 6
176 rdf:type schema:PublicationIssue
177 Nff9ed82aed9c4166be36cff0f947350a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
178 schema:name Renin-Angiotensin System
179 rdf:type schema:DefinedTerm
180 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
181 schema:name Medical and Health Sciences
182 rdf:type schema:DefinedTerm
183 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
184 schema:name Clinical Sciences
185 rdf:type schema:DefinedTerm
186 sg:journal.1101268 schema:issn 0960-8923
187 1708-0428
188 schema:name Obesity Surgery
189 rdf:type schema:Periodical
190 sg:person.01171104613.28 schema:affiliation N242fe039ec124bb4a850b8c5b67f8b6a
191 schema:familyName Ceccarini
192 schema:givenName Giovanni
193 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01171104613.28
194 rdf:type schema:Person
195 sg:person.01217714565.04 schema:affiliation N44987abc12e041429c94c6e9050bab41
196 schema:familyName Abramo
197 schema:givenName Antonio
198 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01217714565.04
199 rdf:type schema:Person
200 sg:person.01226525757.06 schema:affiliation Nabdeba95999343bda58c1c824ecfdd11
201 schema:familyName Santini
202 schema:givenName Ferruccio
203 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01226525757.06
204 rdf:type schema:Person
205 sg:person.01266027765.01 schema:affiliation N00be7b038eea47938709619c29e0f835
206 schema:familyName Di Salvo
207 schema:givenName Claudio
208 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01266027765.01
209 rdf:type schema:Person
210 sg:person.01302451207.28 schema:affiliation N735e2530d2c44bebb5d03c2b449699e7
211 schema:familyName Fierabracci
212 schema:givenName Paola
213 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01302451207.28
214 rdf:type schema:Person
215 sg:person.01313770306.19 schema:affiliation N68515ec5a21f4061bff90e175669153b
216 schema:familyName Salvetti
217 schema:givenName Guido
218 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01313770306.19
219 rdf:type schema:Person
220 sg:person.01346066015.63 schema:affiliation N4ae73ac41b3442ed92ebd5ff3fc410c4
221 schema:familyName Magno
222 schema:givenName Silvia
223 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01346066015.63
224 rdf:type schema:Person
225 sg:person.0614150407.49 schema:affiliation N64fe5c584da3465a8c5b22e62def9a56
226 schema:familyName Piaggi
227 schema:givenName Paolo
228 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0614150407.49
229 rdf:type schema:Person
230 sg:person.0777360014.47 schema:affiliation Ne3ff0067df6343c1953d2fe58704f6bb
231 schema:familyName Vitti
232 schema:givenName Paolo
233 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0777360014.47
234 rdf:type schema:Person
235 sg:pub.10.1007/s11695-009-9973-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018986712
236 https://doi.org/10.1007/s11695-009-9973-9
237 rdf:type schema:CreativeWork
238 sg:pub.10.1186/cc4896 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046631768
239 https://doi.org/10.1186/cc4896
240 rdf:type schema:CreativeWork
241 sg:pub.10.1186/s13054-014-0644-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027369001
242 https://doi.org/10.1186/s13054-014-0644-4
243 rdf:type schema:CreativeWork
244 sg:pub.10.1381/096089200321643511 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007224499
245 https://doi.org/10.1381/096089200321643511
246 rdf:type schema:CreativeWork
247 https://app.dimensions.ai/details/publication/pub.1076813008 schema:CreativeWork
248 https://doi.org/10.1016/s0888-6296(89)97459-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013416812
249 rdf:type schema:CreativeWork
250 https://doi.org/10.1053/j.jvca.2007.12.020 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002178014
251 rdf:type schema:CreativeWork
252 https://doi.org/10.1053/j.jvca.2008.01.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032122653
253 rdf:type schema:CreativeWork
254 https://doi.org/10.1093/bja/86.1.90 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002651097
255 rdf:type schema:CreativeWork
256 https://doi.org/10.1097/00000539-200101000-00006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033661937
257 rdf:type schema:CreativeWork
258 https://doi.org/10.1097/00000539-200204000-00011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052387552
259 rdf:type schema:CreativeWork
260 https://doi.org/10.1097/00000542-200306000-00007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014094587
261 rdf:type schema:CreativeWork
262 https://doi.org/10.1097/hjh.0b013e328010b8f3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021363163
263 rdf:type schema:CreativeWork
264 https://doi.org/10.1097/hjh.0b013e3283537347 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019176222
265 rdf:type schema:CreativeWork
266 https://doi.org/10.1136/pgmj.2010.112987 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012962089
267 rdf:type schema:CreativeWork
268 https://doi.org/10.1213/00000539-199301000-00005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002739971
269 rdf:type schema:CreativeWork
270 https://doi.org/10.1213/00000539-199911000-00012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023802879
271 rdf:type schema:CreativeWork
272 https://doi.org/10.1213/00000539-199912000-00011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009686404
273 rdf:type schema:CreativeWork
274 https://doi.org/10.1213/01.ane.0000146521.68059.a1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009559193
275 rdf:type schema:CreativeWork
276 https://doi.org/10.1213/ane.0000000000000076 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051868231
277 rdf:type schema:CreativeWork
278 https://doi.org/10.2174/0929867311320100008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069163082
279 rdf:type schema:CreativeWork
280 https://doi.org/10.2174/1381612033455413 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069165030
281 rdf:type schema:CreativeWork
 




Preview window. Press ESC to close (or click here)


...