Multi-site harmonization of diffusion MRI data in a registration framework View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2018-02

AUTHORS

Hengameh Mirzaalian, Lipeng Ning, Peter Savadjiev, Ofer Pasternak, Sylvain Bouix, Oleg Michailovich, Sarina Karmacharya, Gerald Grant, Christine E. Marx, Rajendra A. Morey, Laura A. Flashman, Mark S. George, Thomas W. McAllister, Norberto Andaluz, Lori Shutter, Raul Coimbra, Ross D. Zafonte, Mike J. Coleman, Marek Kubicki, Carl-Fredrik Westin, Murray B. Stein, Martha E. Shenton, Yogesh Rathi

ABSTRACT

Diffusion MRI (dMRI) data acquired on different scanners varies significantly in its content throughout the brain even if the acquisition parameters are nearly identical. Thus, proper harmonization of such data sets is necessary to increase the sample size and thereby the statistical power of neuroimaging studies. In this paper, we present a novel approach to harmonize dMRI data (the raw signal, instead of dMRI derived measures such as fractional anisotropy) using rotation invariant spherical harmonic (RISH) features embedded within a multi-modal image registration framework. All dMRI data sets from all sites are registered to a common template and voxel-wise differences in RISH features between sites at a group level are used to harmonize the signal in a subject-specific manner. We validate our method on diffusion data acquired from seven different sites (two GE, three Philips, and two Siemens scanners) on a group of age-matched healthy subjects. We demonstrate the efficacy of our method by statistically comparing diffusion measures such as fractional anisotropy, mean diffusivity and generalized fractional anisotropy across these sites before and after data harmonization. Validation was also done on a group oftest subjects, which were not used to "learn" the harmonization parameters. We also show results using TBSS before and after harmonization for independent validation of the proposed methodology. Using synthetic data, we show that any abnormality in diffusion measures due to disease is preserved during the harmonization process. Our experimental results demonstrate that, for nearly identical acquisition protocol across sites, scanner-specific differences in the signal can be removed using the proposed method in a model independent manner. More... »

PAGES

284-295

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11682-016-9670-y

DOI

http://dx.doi.org/10.1007/s11682-016-9670-y

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1083698654

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/28176263


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0801", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Artificial Intelligence and Image Processing", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/08", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Information and Computing Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Brain", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Computer Simulation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Diffusion Magnetic Resonance Imaging", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Image Processing, Computer-Assisted", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Models, Neurological", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Boston Children's Hospital", 
          "id": "https://www.grid.ac/institutes/grid.2515.3", 
          "name": [
            "Harvard Medical School and Brigham and Women\u2019s Hospital, Boston, MA, USA", 
            "Harvard Medical School and Boston Children\u2019s Hospital, Boston, MA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mirzaalian", 
        "givenName": "Hengameh", 
        "id": "sg:person.01360414170.51", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01360414170.51"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Brigham and Women's Hospital", 
          "id": "https://www.grid.ac/institutes/grid.62560.37", 
          "name": [
            "Harvard Medical School and Brigham and Women\u2019s Hospital, Boston, MA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ning", 
        "givenName": "Lipeng", 
        "id": "sg:person.0713375305.07", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0713375305.07"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Brigham and Women's Hospital", 
          "id": "https://www.grid.ac/institutes/grid.62560.37", 
          "name": [
            "Harvard Medical School and Brigham and Women\u2019s Hospital, Boston, MA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Savadjiev", 
        "givenName": "Peter", 
        "id": "sg:person.01330050765.24", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01330050765.24"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Brigham and Women's Hospital", 
          "id": "https://www.grid.ac/institutes/grid.62560.37", 
          "name": [
            "Harvard Medical School and Brigham and Women\u2019s Hospital, Boston, MA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pasternak", 
        "givenName": "Ofer", 
        "id": "sg:person.0636323570.31", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0636323570.31"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Brigham and Women's Hospital", 
          "id": "https://www.grid.ac/institutes/grid.62560.37", 
          "name": [
            "Harvard Medical School and Brigham and Women\u2019s Hospital, Boston, MA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bouix", 
        "givenName": "Sylvain", 
        "id": "sg:person.01363713425.21", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01363713425.21"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Waterloo", 
          "id": "https://www.grid.ac/institutes/grid.46078.3d", 
          "name": [
            "University of Waterloo, Waterloo, ON, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Michailovich", 
        "givenName": "Oleg", 
        "id": "sg:person.0637150473.50", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0637150473.50"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Brigham and Women's Hospital", 
          "id": "https://www.grid.ac/institutes/grid.62560.37", 
          "name": [
            "Harvard Medical School and Brigham and Women\u2019s Hospital, Boston, MA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Karmacharya", 
        "givenName": "Sarina", 
        "id": "sg:person.014631565767.46", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014631565767.46"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Stanford Medicine", 
          "id": "https://www.grid.ac/institutes/grid.240952.8", 
          "name": [
            "Stanford University Medical Center (Previously Duke University), Palo Alto, CA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Grant", 
        "givenName": "Gerald", 
        "id": "sg:person.0620743331.37", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0620743331.37"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Duke University", 
          "id": "https://www.grid.ac/institutes/grid.26009.3d", 
          "name": [
            "Medical Center and VA Mid-Atlantic MIRECC, Duke University, Durham, NC, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Marx", 
        "givenName": "Christine E.", 
        "id": "sg:person.01153215327.02", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01153215327.02"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Duke University", 
          "id": "https://www.grid.ac/institutes/grid.26009.3d", 
          "name": [
            "Medical Center and VA Mid-Atlantic MIRECC, Duke University, Durham, NC, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Morey", 
        "givenName": "Rajendra A.", 
        "id": "sg:person.01230355232.44", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01230355232.44"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Dartmouth College", 
          "id": "https://www.grid.ac/institutes/grid.254880.3", 
          "name": [
            "Hanover and Geisel School of Medicine at Dartmouth, Dartmouth University, Hanover, NH, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Flashman", 
        "givenName": "Laura A.", 
        "id": "sg:person.0576523665.27", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0576523665.27"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Ralph H. Johnson VA Medical Center, Medical University of South Carolina, Charleston, SC, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "George", 
        "givenName": "Mark S.", 
        "id": "sg:person.01362225036.04", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01362225036.04"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Dartmouth College", 
          "id": "https://www.grid.ac/institutes/grid.254880.3", 
          "name": [
            "Geisel School of Medicine at Dartmouth (original) and Indiana University School of Medicine (current), 1 Rope Ferry Rd, 03755, Hanover, NH, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "McAllister", 
        "givenName": "Thomas W.", 
        "id": "sg:person.01270162053.14", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01270162053.14"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Cincinnati", 
          "id": "https://www.grid.ac/institutes/grid.24827.3b", 
          "name": [
            "Department of Neurosurgery, University of Cincinnati (UC) College of Medicine; Neurotrauma Center at UC Neuroscience Institute; and Mayfield Clinic, Cincinnati, OH, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Andaluz", 
        "givenName": "Norberto", 
        "id": "sg:person.0727165100.70", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0727165100.70"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Pittsburgh", 
          "id": "https://www.grid.ac/institutes/grid.21925.3d", 
          "name": [
            "University of Pittsburgh School of Medicine (Previously University of Cincinnati), Pittsburgh, PA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shutter", 
        "givenName": "Lori", 
        "id": "sg:person.01047573376.12", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01047573376.12"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of California, San Diego", 
          "id": "https://www.grid.ac/institutes/grid.266100.3", 
          "name": [
            "Department of Surgery, University of California, San Diego, CA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Coimbra", 
        "givenName": "Raul", 
        "id": "sg:person.01234475000.25", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01234475000.25"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Spaulding Rehabilitation Hospital", 
          "id": "https://www.grid.ac/institutes/grid.416228.b", 
          "name": [
            "Spaulding Rehabilitation Hospital and Harvard Medical School, Boston, MA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Zafonte", 
        "givenName": "Ross D.", 
        "id": "sg:person.010210711477.16", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010210711477.16"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Brigham and Women's Hospital", 
          "id": "https://www.grid.ac/institutes/grid.62560.37", 
          "name": [
            "Harvard Medical School and Brigham and Women\u2019s Hospital, Boston, MA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Coleman", 
        "givenName": "Mike J.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Brigham and Women's Hospital", 
          "id": "https://www.grid.ac/institutes/grid.62560.37", 
          "name": [
            "Harvard Medical School and Brigham and Women\u2019s Hospital, Boston, MA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kubicki", 
        "givenName": "Marek", 
        "id": "sg:person.01064143524.16", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01064143524.16"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Brigham and Women's Hospital", 
          "id": "https://www.grid.ac/institutes/grid.62560.37", 
          "name": [
            "Harvard Medical School and Brigham and Women\u2019s Hospital, Boston, MA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Westin", 
        "givenName": "Carl-Fredrik", 
        "id": "sg:person.013154051237.05", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013154051237.05"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of California, San Diego", 
          "id": "https://www.grid.ac/institutes/grid.266100.3", 
          "name": [
            "University of California, San Diego, San Diego, CA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Stein", 
        "givenName": "Murray B.", 
        "id": "sg:person.015007402217.85", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015007402217.85"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "VA Boston Healthcare System", 
          "id": "https://www.grid.ac/institutes/grid.410370.1", 
          "name": [
            "Harvard Medical School and Brigham and Women\u2019s Hospital, Boston, MA, USA", 
            "VA Boston Healthcare System, Boston, MA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shenton", 
        "givenName": "Martha E.", 
        "id": "sg:person.0653653526.45", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0653653526.45"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Brigham and Women's Hospital", 
          "id": "https://www.grid.ac/institutes/grid.62560.37", 
          "name": [
            "Harvard Medical School and Brigham and Women\u2019s Hospital, Boston, MA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rathi", 
        "givenName": "Yogesh", 
        "id": "sg:person.0754535725.96", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0754535725.96"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1002/mrm.25754", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005342273"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-3-319-24553-9_2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006712876", 
          "https://doi.org/10.1007/978-3-319-24553-9_2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.neuroimage.2015.06.078", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009197546"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.neuroimage.2016.01.061", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010760558"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.neuroimage.2013.04.061", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011860905"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/hbm.22338", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021469258"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.neuroimage.2006.01.024", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022430340"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.neuroimage.2006.02.024", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023372670"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.neuroimage.2014.04.027", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029378313"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/mrm.21277", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029886112"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.neuroimage.2007.02.016", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031799052"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.neuroimage.2014.03.033", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033795826"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0086280", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046238913"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.neuroimage.2016.04.041", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048378340"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.neuroimage.2008.12.039", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049371092"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/brain.2012.0112", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059239720"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2018-02", 
    "datePublishedReg": "2018-02-01", 
    "description": "Diffusion MRI (dMRI) data acquired on different scanners varies significantly in its content throughout the brain even if the acquisition parameters are nearly identical. Thus, proper harmonization of such data sets is necessary to increase the sample size and thereby the statistical power of neuroimaging studies. In this paper, we present a novel approach to harmonize dMRI data (the raw signal, instead of dMRI derived measures such as fractional anisotropy) using rotation invariant spherical harmonic (RISH) features embedded within a multi-modal image registration framework. All dMRI data sets from all sites are registered to a common template and voxel-wise differences in RISH features between sites at a group level are used to harmonize the signal in a subject-specific manner. We validate our method on diffusion data acquired from seven different sites (two GE, three Philips, and two Siemens scanners) on a group of age-matched healthy subjects. We demonstrate the efficacy of our method by statistically comparing diffusion measures such as fractional anisotropy, mean diffusivity and generalized fractional anisotropy across these sites before and after data harmonization. Validation was also done on a group oftest subjects, which were not used to \"learn\" the harmonization parameters. We also show results using TBSS before and after harmonization for independent validation of the proposed methodology. Using synthetic data, we show that any abnormality in diffusion measures due to disease is preserved during the harmonization process. Our experimental results demonstrate that, for nearly identical acquisition protocol across sites, scanner-specific differences in the signal can be removed using the proposed method in a model independent manner.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s11682-016-9670-y", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.2616139", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2551032", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1038420", 
        "issn": [
          "1931-7557", 
          "1931-7565"
        ], 
        "name": "Brain Imaging and Behavior", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "12"
      }
    ], 
    "name": "Multi-site harmonization of diffusion MRI data in a registration framework", 
    "pagination": "284-295", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "786459ab883dd9cb297fc784de733b2e17fa22dd5dd2a1a8ccdf91b35c2491fc"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "28176263"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101300405"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s11682-016-9670-y"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1083698654"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s11682-016-9670-y", 
      "https://app.dimensions.ai/details/publication/pub.1083698654"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T10:03", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000347_0000000347/records_89824_00000002.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1007%2Fs11682-016-9670-y"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s11682-016-9670-y'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s11682-016-9670-y'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s11682-016-9670-y'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s11682-016-9670-y'


 

This table displays all metadata directly associated to this object as RDF triples.

347 TRIPLES      21 PREDICATES      54 URIs      30 LITERALS      18 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s11682-016-9670-y schema:about N09f8b67fde114bf3aad6fd993c52db78
2 N1a5a71ca3b954774b64fc13d398b3eea
3 N218c8e935a724604bc9c4b125aaa96db
4 N4d4061da058843359811d195821ee1bc
5 N6e57d9bc6cba4415a30bbfbb676b0900
6 N6e7cfd43a9c447cfb0fcab219888656f
7 N78afe3ed59644fcda57acb0923bb8300
8 Nc5a8129a1cf24a2aa8921136b90730d8
9 Nff342a835f2f4242b7ee12ac15f8eb1e
10 anzsrc-for:08
11 anzsrc-for:0801
12 schema:author N3e97e80beebc42439326081917403e65
13 schema:citation sg:pub.10.1007/978-3-319-24553-9_2
14 https://doi.org/10.1002/hbm.22338
15 https://doi.org/10.1002/mrm.21277
16 https://doi.org/10.1002/mrm.25754
17 https://doi.org/10.1016/j.neuroimage.2006.01.024
18 https://doi.org/10.1016/j.neuroimage.2006.02.024
19 https://doi.org/10.1016/j.neuroimage.2007.02.016
20 https://doi.org/10.1016/j.neuroimage.2008.12.039
21 https://doi.org/10.1016/j.neuroimage.2013.04.061
22 https://doi.org/10.1016/j.neuroimage.2014.03.033
23 https://doi.org/10.1016/j.neuroimage.2014.04.027
24 https://doi.org/10.1016/j.neuroimage.2015.06.078
25 https://doi.org/10.1016/j.neuroimage.2016.01.061
26 https://doi.org/10.1016/j.neuroimage.2016.04.041
27 https://doi.org/10.1089/brain.2012.0112
28 https://doi.org/10.1371/journal.pone.0086280
29 schema:datePublished 2018-02
30 schema:datePublishedReg 2018-02-01
31 schema:description Diffusion MRI (dMRI) data acquired on different scanners varies significantly in its content throughout the brain even if the acquisition parameters are nearly identical. Thus, proper harmonization of such data sets is necessary to increase the sample size and thereby the statistical power of neuroimaging studies. In this paper, we present a novel approach to harmonize dMRI data (the raw signal, instead of dMRI derived measures such as fractional anisotropy) using rotation invariant spherical harmonic (RISH) features embedded within a multi-modal image registration framework. All dMRI data sets from all sites are registered to a common template and voxel-wise differences in RISH features between sites at a group level are used to harmonize the signal in a subject-specific manner. We validate our method on diffusion data acquired from seven different sites (two GE, three Philips, and two Siemens scanners) on a group of age-matched healthy subjects. We demonstrate the efficacy of our method by statistically comparing diffusion measures such as fractional anisotropy, mean diffusivity and generalized fractional anisotropy across these sites before and after data harmonization. Validation was also done on a group oftest subjects, which were not used to "learn" the harmonization parameters. We also show results using TBSS before and after harmonization for independent validation of the proposed methodology. Using synthetic data, we show that any abnormality in diffusion measures due to disease is preserved during the harmonization process. Our experimental results demonstrate that, for nearly identical acquisition protocol across sites, scanner-specific differences in the signal can be removed using the proposed method in a model independent manner.
32 schema:genre research_article
33 schema:inLanguage en
34 schema:isAccessibleForFree false
35 schema:isPartOf N57d04eda37a24830b68e4c8a821cbe92
36 N70bd8c5524ae4dc9854bdcac731bfb40
37 sg:journal.1038420
38 schema:name Multi-site harmonization of diffusion MRI data in a registration framework
39 schema:pagination 284-295
40 schema:productId N0301f60bc37341a1a30ba136469a82df
41 N073d99bb9850419489208c778e876101
42 N2054c003372642f09fc3e7dcc04b45b4
43 N3399b89c32984a8c8aec92a04aaa5c08
44 N6b8226dd60ed4275a2d0c5bc56e1ffc0
45 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083698654
46 https://doi.org/10.1007/s11682-016-9670-y
47 schema:sdDatePublished 2019-04-11T10:03
48 schema:sdLicense https://scigraph.springernature.com/explorer/license/
49 schema:sdPublisher N289eef4be0ea470486ac89d2f37787b0
50 schema:url https://link.springer.com/10.1007%2Fs11682-016-9670-y
51 sgo:license sg:explorer/license/
52 sgo:sdDataset articles
53 rdf:type schema:ScholarlyArticle
54 N0301f60bc37341a1a30ba136469a82df schema:name dimensions_id
55 schema:value pub.1083698654
56 rdf:type schema:PropertyValue
57 N03ec9b2a3fff4119993bddca7d3528f2 rdf:first sg:person.013154051237.05
58 rdf:rest Nea59d7ec0e1746a78916194f78a54368
59 N04af17c2ec254f5bb2839b0cc7392a08 rdf:first sg:person.01230355232.44
60 rdf:rest Nfda8a472f7cb4328a26f4e0836914de9
61 N073d99bb9850419489208c778e876101 schema:name doi
62 schema:value 10.1007/s11682-016-9670-y
63 rdf:type schema:PropertyValue
64 N09f8b67fde114bf3aad6fd993c52db78 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
65 schema:name Male
66 rdf:type schema:DefinedTerm
67 N17bfad4a0a3646c89c3d7ced026763c0 rdf:first sg:person.01234475000.25
68 rdf:rest Na0dae03df0c04580a1a2e93b6511ad49
69 N1a5a71ca3b954774b64fc13d398b3eea schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
70 schema:name Humans
71 rdf:type schema:DefinedTerm
72 N2054c003372642f09fc3e7dcc04b45b4 schema:name pubmed_id
73 schema:value 28176263
74 rdf:type schema:PropertyValue
75 N218c8e935a724604bc9c4b125aaa96db schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
76 schema:name Diffusion Magnetic Resonance Imaging
77 rdf:type schema:DefinedTerm
78 N282c9c23e0b64303add4c1a313b1a6ec rdf:first sg:person.0727165100.70
79 rdf:rest Nc878fa43ed91467394ff8d0eb4e0a729
80 N289eef4be0ea470486ac89d2f37787b0 schema:name Springer Nature - SN SciGraph project
81 rdf:type schema:Organization
82 N3399b89c32984a8c8aec92a04aaa5c08 schema:name readcube_id
83 schema:value 786459ab883dd9cb297fc784de733b2e17fa22dd5dd2a1a8ccdf91b35c2491fc
84 rdf:type schema:PropertyValue
85 N3e97e80beebc42439326081917403e65 rdf:first sg:person.01360414170.51
86 rdf:rest Neabce7a7673946949490f89ec9f117e8
87 N4c56448185374f6d8b64580332d4a9a8 rdf:first sg:person.01270162053.14
88 rdf:rest N282c9c23e0b64303add4c1a313b1a6ec
89 N4d4061da058843359811d195821ee1bc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
90 schema:name Brain
91 rdf:type schema:DefinedTerm
92 N57d04eda37a24830b68e4c8a821cbe92 schema:issueNumber 1
93 rdf:type schema:PublicationIssue
94 N5dbf279f2cf640a2b0b20f077d0962f5 schema:name Ralph H. Johnson VA Medical Center, Medical University of South Carolina, Charleston, SC, USA
95 rdf:type schema:Organization
96 N660376009e5548b8999ec11d6a43dcc7 rdf:first N6b026ac78a6a43839cc6673bc7038059
97 rdf:rest Nfe8e67bfde5d45709983f6ae7f57f184
98 N6b026ac78a6a43839cc6673bc7038059 schema:affiliation https://www.grid.ac/institutes/grid.62560.37
99 schema:familyName Coleman
100 schema:givenName Mike J.
101 rdf:type schema:Person
102 N6b8226dd60ed4275a2d0c5bc56e1ffc0 schema:name nlm_unique_id
103 schema:value 101300405
104 rdf:type schema:PropertyValue
105 N6d9bce1a453b41dab9cf3b37c23a9bc6 rdf:first sg:person.0754535725.96
106 rdf:rest rdf:nil
107 N6e57d9bc6cba4415a30bbfbb676b0900 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
108 schema:name Adult
109 rdf:type schema:DefinedTerm
110 N6e7cfd43a9c447cfb0fcab219888656f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
111 schema:name Models, Neurological
112 rdf:type schema:DefinedTerm
113 N70bd8c5524ae4dc9854bdcac731bfb40 schema:volumeNumber 12
114 rdf:type schema:PublicationVolume
115 N71300148f58f415a89a76433db654379 rdf:first sg:person.01362225036.04
116 rdf:rest N4c56448185374f6d8b64580332d4a9a8
117 N78afe3ed59644fcda57acb0923bb8300 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
118 schema:name Image Processing, Computer-Assisted
119 rdf:type schema:DefinedTerm
120 N87ab62db4da94c3aaa6a03f81da32945 rdf:first sg:person.01363713425.21
121 rdf:rest N8b3707f2ea1941899e7bd4863df83358
122 N8b3707f2ea1941899e7bd4863df83358 rdf:first sg:person.0637150473.50
123 rdf:rest Nf195c42d33ee44ff920cf840d186c09a
124 Na0dae03df0c04580a1a2e93b6511ad49 rdf:first sg:person.010210711477.16
125 rdf:rest N660376009e5548b8999ec11d6a43dcc7
126 Na3cedc5a37ba4c5292153575f97e5846 rdf:first sg:person.01330050765.24
127 rdf:rest Nbfa8e81f7a424eaea69e0a2696cbcb20
128 Nbfa8e81f7a424eaea69e0a2696cbcb20 rdf:first sg:person.0636323570.31
129 rdf:rest N87ab62db4da94c3aaa6a03f81da32945
130 Nc5a8129a1cf24a2aa8921136b90730d8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
131 schema:name Female
132 rdf:type schema:DefinedTerm
133 Nc878fa43ed91467394ff8d0eb4e0a729 rdf:first sg:person.01047573376.12
134 rdf:rest N17bfad4a0a3646c89c3d7ced026763c0
135 Ncd5f5dd60788442d84f31552db78a363 rdf:first sg:person.0620743331.37
136 rdf:rest Ne9bc50e3208f44aabbbe1d652451577d
137 Ne9bc50e3208f44aabbbe1d652451577d rdf:first sg:person.01153215327.02
138 rdf:rest N04af17c2ec254f5bb2839b0cc7392a08
139 Nea59d7ec0e1746a78916194f78a54368 rdf:first sg:person.015007402217.85
140 rdf:rest Ned84d17d28874e7c9def48e55d280f35
141 Neabce7a7673946949490f89ec9f117e8 rdf:first sg:person.0713375305.07
142 rdf:rest Na3cedc5a37ba4c5292153575f97e5846
143 Ned84d17d28874e7c9def48e55d280f35 rdf:first sg:person.0653653526.45
144 rdf:rest N6d9bce1a453b41dab9cf3b37c23a9bc6
145 Nf195c42d33ee44ff920cf840d186c09a rdf:first sg:person.014631565767.46
146 rdf:rest Ncd5f5dd60788442d84f31552db78a363
147 Nfda8a472f7cb4328a26f4e0836914de9 rdf:first sg:person.0576523665.27
148 rdf:rest N71300148f58f415a89a76433db654379
149 Nfe8e67bfde5d45709983f6ae7f57f184 rdf:first sg:person.01064143524.16
150 rdf:rest N03ec9b2a3fff4119993bddca7d3528f2
151 Nff342a835f2f4242b7ee12ac15f8eb1e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
152 schema:name Computer Simulation
153 rdf:type schema:DefinedTerm
154 anzsrc-for:08 schema:inDefinedTermSet anzsrc-for:
155 schema:name Information and Computing Sciences
156 rdf:type schema:DefinedTerm
157 anzsrc-for:0801 schema:inDefinedTermSet anzsrc-for:
158 schema:name Artificial Intelligence and Image Processing
159 rdf:type schema:DefinedTerm
160 sg:grant.2551032 http://pending.schema.org/fundedItem sg:pub.10.1007/s11682-016-9670-y
161 rdf:type schema:MonetaryGrant
162 sg:grant.2616139 http://pending.schema.org/fundedItem sg:pub.10.1007/s11682-016-9670-y
163 rdf:type schema:MonetaryGrant
164 sg:journal.1038420 schema:issn 1931-7557
165 1931-7565
166 schema:name Brain Imaging and Behavior
167 rdf:type schema:Periodical
168 sg:person.010210711477.16 schema:affiliation https://www.grid.ac/institutes/grid.416228.b
169 schema:familyName Zafonte
170 schema:givenName Ross D.
171 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010210711477.16
172 rdf:type schema:Person
173 sg:person.01047573376.12 schema:affiliation https://www.grid.ac/institutes/grid.21925.3d
174 schema:familyName Shutter
175 schema:givenName Lori
176 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01047573376.12
177 rdf:type schema:Person
178 sg:person.01064143524.16 schema:affiliation https://www.grid.ac/institutes/grid.62560.37
179 schema:familyName Kubicki
180 schema:givenName Marek
181 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01064143524.16
182 rdf:type schema:Person
183 sg:person.01153215327.02 schema:affiliation https://www.grid.ac/institutes/grid.26009.3d
184 schema:familyName Marx
185 schema:givenName Christine E.
186 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01153215327.02
187 rdf:type schema:Person
188 sg:person.01230355232.44 schema:affiliation https://www.grid.ac/institutes/grid.26009.3d
189 schema:familyName Morey
190 schema:givenName Rajendra A.
191 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01230355232.44
192 rdf:type schema:Person
193 sg:person.01234475000.25 schema:affiliation https://www.grid.ac/institutes/grid.266100.3
194 schema:familyName Coimbra
195 schema:givenName Raul
196 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01234475000.25
197 rdf:type schema:Person
198 sg:person.01270162053.14 schema:affiliation https://www.grid.ac/institutes/grid.254880.3
199 schema:familyName McAllister
200 schema:givenName Thomas W.
201 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01270162053.14
202 rdf:type schema:Person
203 sg:person.013154051237.05 schema:affiliation https://www.grid.ac/institutes/grid.62560.37
204 schema:familyName Westin
205 schema:givenName Carl-Fredrik
206 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013154051237.05
207 rdf:type schema:Person
208 sg:person.01330050765.24 schema:affiliation https://www.grid.ac/institutes/grid.62560.37
209 schema:familyName Savadjiev
210 schema:givenName Peter
211 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01330050765.24
212 rdf:type schema:Person
213 sg:person.01360414170.51 schema:affiliation https://www.grid.ac/institutes/grid.2515.3
214 schema:familyName Mirzaalian
215 schema:givenName Hengameh
216 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01360414170.51
217 rdf:type schema:Person
218 sg:person.01362225036.04 schema:affiliation N5dbf279f2cf640a2b0b20f077d0962f5
219 schema:familyName George
220 schema:givenName Mark S.
221 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01362225036.04
222 rdf:type schema:Person
223 sg:person.01363713425.21 schema:affiliation https://www.grid.ac/institutes/grid.62560.37
224 schema:familyName Bouix
225 schema:givenName Sylvain
226 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01363713425.21
227 rdf:type schema:Person
228 sg:person.014631565767.46 schema:affiliation https://www.grid.ac/institutes/grid.62560.37
229 schema:familyName Karmacharya
230 schema:givenName Sarina
231 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014631565767.46
232 rdf:type schema:Person
233 sg:person.015007402217.85 schema:affiliation https://www.grid.ac/institutes/grid.266100.3
234 schema:familyName Stein
235 schema:givenName Murray B.
236 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015007402217.85
237 rdf:type schema:Person
238 sg:person.0576523665.27 schema:affiliation https://www.grid.ac/institutes/grid.254880.3
239 schema:familyName Flashman
240 schema:givenName Laura A.
241 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0576523665.27
242 rdf:type schema:Person
243 sg:person.0620743331.37 schema:affiliation https://www.grid.ac/institutes/grid.240952.8
244 schema:familyName Grant
245 schema:givenName Gerald
246 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0620743331.37
247 rdf:type schema:Person
248 sg:person.0636323570.31 schema:affiliation https://www.grid.ac/institutes/grid.62560.37
249 schema:familyName Pasternak
250 schema:givenName Ofer
251 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0636323570.31
252 rdf:type schema:Person
253 sg:person.0637150473.50 schema:affiliation https://www.grid.ac/institutes/grid.46078.3d
254 schema:familyName Michailovich
255 schema:givenName Oleg
256 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0637150473.50
257 rdf:type schema:Person
258 sg:person.0653653526.45 schema:affiliation https://www.grid.ac/institutes/grid.410370.1
259 schema:familyName Shenton
260 schema:givenName Martha E.
261 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0653653526.45
262 rdf:type schema:Person
263 sg:person.0713375305.07 schema:affiliation https://www.grid.ac/institutes/grid.62560.37
264 schema:familyName Ning
265 schema:givenName Lipeng
266 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0713375305.07
267 rdf:type schema:Person
268 sg:person.0727165100.70 schema:affiliation https://www.grid.ac/institutes/grid.24827.3b
269 schema:familyName Andaluz
270 schema:givenName Norberto
271 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0727165100.70
272 rdf:type schema:Person
273 sg:person.0754535725.96 schema:affiliation https://www.grid.ac/institutes/grid.62560.37
274 schema:familyName Rathi
275 schema:givenName Yogesh
276 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0754535725.96
277 rdf:type schema:Person
278 sg:pub.10.1007/978-3-319-24553-9_2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006712876
279 https://doi.org/10.1007/978-3-319-24553-9_2
280 rdf:type schema:CreativeWork
281 https://doi.org/10.1002/hbm.22338 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021469258
282 rdf:type schema:CreativeWork
283 https://doi.org/10.1002/mrm.21277 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029886112
284 rdf:type schema:CreativeWork
285 https://doi.org/10.1002/mrm.25754 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005342273
286 rdf:type schema:CreativeWork
287 https://doi.org/10.1016/j.neuroimage.2006.01.024 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022430340
288 rdf:type schema:CreativeWork
289 https://doi.org/10.1016/j.neuroimage.2006.02.024 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023372670
290 rdf:type schema:CreativeWork
291 https://doi.org/10.1016/j.neuroimage.2007.02.016 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031799052
292 rdf:type schema:CreativeWork
293 https://doi.org/10.1016/j.neuroimage.2008.12.039 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049371092
294 rdf:type schema:CreativeWork
295 https://doi.org/10.1016/j.neuroimage.2013.04.061 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011860905
296 rdf:type schema:CreativeWork
297 https://doi.org/10.1016/j.neuroimage.2014.03.033 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033795826
298 rdf:type schema:CreativeWork
299 https://doi.org/10.1016/j.neuroimage.2014.04.027 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029378313
300 rdf:type schema:CreativeWork
301 https://doi.org/10.1016/j.neuroimage.2015.06.078 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009197546
302 rdf:type schema:CreativeWork
303 https://doi.org/10.1016/j.neuroimage.2016.01.061 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010760558
304 rdf:type schema:CreativeWork
305 https://doi.org/10.1016/j.neuroimage.2016.04.041 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048378340
306 rdf:type schema:CreativeWork
307 https://doi.org/10.1089/brain.2012.0112 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059239720
308 rdf:type schema:CreativeWork
309 https://doi.org/10.1371/journal.pone.0086280 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046238913
310 rdf:type schema:CreativeWork
311 https://www.grid.ac/institutes/grid.21925.3d schema:alternateName University of Pittsburgh
312 schema:name University of Pittsburgh School of Medicine (Previously University of Cincinnati), Pittsburgh, PA, USA
313 rdf:type schema:Organization
314 https://www.grid.ac/institutes/grid.240952.8 schema:alternateName Stanford Medicine
315 schema:name Stanford University Medical Center (Previously Duke University), Palo Alto, CA, USA
316 rdf:type schema:Organization
317 https://www.grid.ac/institutes/grid.24827.3b schema:alternateName University of Cincinnati
318 schema:name Department of Neurosurgery, University of Cincinnati (UC) College of Medicine; Neurotrauma Center at UC Neuroscience Institute; and Mayfield Clinic, Cincinnati, OH, USA
319 rdf:type schema:Organization
320 https://www.grid.ac/institutes/grid.2515.3 schema:alternateName Boston Children's Hospital
321 schema:name Harvard Medical School and Boston Children’s Hospital, Boston, MA, USA
322 Harvard Medical School and Brigham and Women’s Hospital, Boston, MA, USA
323 rdf:type schema:Organization
324 https://www.grid.ac/institutes/grid.254880.3 schema:alternateName Dartmouth College
325 schema:name Geisel School of Medicine at Dartmouth (original) and Indiana University School of Medicine (current), 1 Rope Ferry Rd, 03755, Hanover, NH, USA
326 Hanover and Geisel School of Medicine at Dartmouth, Dartmouth University, Hanover, NH, USA
327 rdf:type schema:Organization
328 https://www.grid.ac/institutes/grid.26009.3d schema:alternateName Duke University
329 schema:name Medical Center and VA Mid-Atlantic MIRECC, Duke University, Durham, NC, USA
330 rdf:type schema:Organization
331 https://www.grid.ac/institutes/grid.266100.3 schema:alternateName University of California, San Diego
332 schema:name Department of Surgery, University of California, San Diego, CA, USA
333 University of California, San Diego, San Diego, CA, USA
334 rdf:type schema:Organization
335 https://www.grid.ac/institutes/grid.410370.1 schema:alternateName VA Boston Healthcare System
336 schema:name Harvard Medical School and Brigham and Women’s Hospital, Boston, MA, USA
337 VA Boston Healthcare System, Boston, MA, USA
338 rdf:type schema:Organization
339 https://www.grid.ac/institutes/grid.416228.b schema:alternateName Spaulding Rehabilitation Hospital
340 schema:name Spaulding Rehabilitation Hospital and Harvard Medical School, Boston, MA, USA
341 rdf:type schema:Organization
342 https://www.grid.ac/institutes/grid.46078.3d schema:alternateName University of Waterloo
343 schema:name University of Waterloo, Waterloo, ON, Canada
344 rdf:type schema:Organization
345 https://www.grid.ac/institutes/grid.62560.37 schema:alternateName Brigham and Women's Hospital
346 schema:name Harvard Medical School and Brigham and Women’s Hospital, Boston, MA, USA
347 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...