Treatment of uncomplicated recurrent urinary tract infection with Chinese medicine formula: A randomized controlled trial View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-01

AUTHORS

Shi-wei Liu, Jie Guo, Wei-kang Wu, Ze-liang Chen, Ning Zhang

ABSTRACT

OBJECTIVE: To evaluate Chinese medicine (CM) formula Bazheng Powder () as an alternative therapeutic option for female patients with recurrent urinary tract infection (RUTI). METHODS: A randomized double-blinded trial was performed. Eligible female patients with RUTI were recruited from one hospital and two community health centers. By using a blocked randomization scheme, participants were randomized to receive a CM formula (10 herbs) for 4 weeks or antibiotics for 1 week, followed by 3 weeks of placebo. Clinical cure rate and microbiological cure and recurrence after treatment were evaluated. RESULTS: A total 122 eligible patients were enrolled, with 61 cases in each group. The clinical cure rate by the intentto- treatment approach was 90.2% for the CM group and 82.0% for the antibiotics group (P>0.05). Bacteria were cleared from 88.5% (54/61) of patients in the CM group and 82.0% (50/61) in the antibiotics group. The recurrence rate in recovered patients at the 6-month follow-up was 9.1% (5/61) and 14.0 (7/61) in the CM and antibiotics groups, respectively (P>0.05). CONCLUSION: CM formula Bazheng Powder is a good alternative option for RUTI treatment. (Registration No. NCT01745328). More... »

PAGES

1-7

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http://scigraph.springernature.com/pub.10.1007/s11655-017-2960-4

DOI

http://dx.doi.org/10.1007/s11655-017-2960-4

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https://app.dimensions.ai/details/publication/pub.1090880984

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/28741061


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