Effects of humic acids in vitro View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2011-04-13

AUTHORS

Janka Vašková, Beáta Veliká, Martina Pilátová, Ivan Kron, Ladislav Vaško

ABSTRACT

Humic acids are known for their overall positive health and productivity effects in animal feeding trials and, controversially, as an aetiological factor of cancer. We tried to assess the in vitro effect of humic acids from a selected source in Slovakia when used at recommended prophylactic dosage. We investigated antioxidant properties, enzymatic and non-enzymatic antioxidant defence system in liver mitochondria and cultured cancer cell lines in vitro. We observed a significant decrease in superoxide dismutase activity after humic acids treatment irrespective of dissolving in dimethyl sulphoxide or direct addition to mitochondria suspension in a respiration medium. Activities of other antioxidant enzymes measured, such as glutathione peroxidase and glutathione reductase, showed no significant differences from the control as well as the reduced glutathione content. Percentage of inhibition by humic acids of superoxide radical indicated lower efficacy compared with that of hydroxyl radical. Survival of six different cancer cells lines indicated that only the acute T lymphoblastic leukaemia cell line was sensitive to the tested humic acids. Despite relatively low solubility in aqueous solutions, humic acids from the selected source participated in redox regulation. By recapturing the radicals, humic acids reloaded the antioxidant defensive mechanism. Results from in vitro study conducted with humic acids from the natural source showed potential of these substances as promising immunity enhancing agents. More... »

PAGES

376-382

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11626-011-9405-8

DOI

http://dx.doi.org/10.1007/s11626-011-9405-8

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1019151387

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/21487922


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1115", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Pharmacology and Pharmaceutical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antioxidants", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Dose-Response Relationship, Drug", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "HeLa Cells", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humic Substances", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hydroxyl Radical", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rats", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rats, Wistar", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Superoxide Dismutase", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Tumor Cells, Cultured", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Medical Chemistry, Biochemistry and Clinical Biochemistry, Faculty of Medicine, Pavol Jozef \u0160af\u00e1rik University in Ko\u0161ice, Tr. SNP 1, 040 11, Ko\u0161ice, Slovak Republic", 
          "id": "http://www.grid.ac/institutes/grid.11175.33", 
          "name": [
            "Department of Medical Chemistry, Biochemistry and Clinical Biochemistry, Faculty of Medicine, Pavol Jozef \u0160af\u00e1rik University in Ko\u0161ice, Tr. SNP 1, 040 11, Ko\u0161ice, Slovak Republic"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Va\u0161kov\u00e1", 
        "givenName": "Janka", 
        "id": "sg:person.0761317742.71", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0761317742.71"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Medical Chemistry, Biochemistry and Clinical Biochemistry, Faculty of Medicine, Pavol Jozef \u0160af\u00e1rik University in Ko\u0161ice, Tr. SNP 1, 040 11, Ko\u0161ice, Slovak Republic", 
          "id": "http://www.grid.ac/institutes/grid.11175.33", 
          "name": [
            "Department of Medical Chemistry, Biochemistry and Clinical Biochemistry, Faculty of Medicine, Pavol Jozef \u0160af\u00e1rik University in Ko\u0161ice, Tr. SNP 1, 040 11, Ko\u0161ice, Slovak Republic"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Velik\u00e1", 
        "givenName": "Be\u00e1ta", 
        "id": "sg:person.01112765170.21", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01112765170.21"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Pharmacology, Faculty of Medicine, Pavol Jozef \u0160af\u00e1rik University in Ko\u0161ice, Ko\u0161ice, Slovak Republic", 
          "id": "http://www.grid.ac/institutes/grid.11175.33", 
          "name": [
            "Department of Pharmacology, Faculty of Medicine, Pavol Jozef \u0160af\u00e1rik University in Ko\u0161ice, Ko\u0161ice, Slovak Republic"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pil\u00e1tov\u00e1", 
        "givenName": "Martina", 
        "id": "sg:person.0767754015.15", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0767754015.15"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Medical Chemistry, Biochemistry and Clinical Biochemistry, Faculty of Medicine, Pavol Jozef \u0160af\u00e1rik University in Ko\u0161ice, Tr. SNP 1, 040 11, Ko\u0161ice, Slovak Republic", 
          "id": "http://www.grid.ac/institutes/grid.11175.33", 
          "name": [
            "Department of Medical Chemistry, Biochemistry and Clinical Biochemistry, Faculty of Medicine, Pavol Jozef \u0160af\u00e1rik University in Ko\u0161ice, Tr. SNP 1, 040 11, Ko\u0161ice, Slovak Republic"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kron", 
        "givenName": "Ivan", 
        "id": "sg:person.01331762451.62", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01331762451.62"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Medical Chemistry, Biochemistry and Clinical Biochemistry, Faculty of Medicine, Pavol Jozef \u0160af\u00e1rik University in Ko\u0161ice, Tr. SNP 1, 040 11, Ko\u0161ice, Slovak Republic", 
          "id": "http://www.grid.ac/institutes/grid.11175.33", 
          "name": [
            "Department of Medical Chemistry, Biochemistry and Clinical Biochemistry, Faculty of Medicine, Pavol Jozef \u0160af\u00e1rik University in Ko\u0161ice, Tr. SNP 1, 040 11, Ko\u0161ice, Slovak Republic"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Va\u0161ko", 
        "givenName": "Ladislav", 
        "id": "sg:person.01143661542.87", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01143661542.87"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1023/b:ifla.0000039563.90066.5d", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011512555", 
          "https://doi.org/10.1023/b:ifla.0000039563.90066.5d"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s003740000209", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051410876", 
          "https://doi.org/10.1007/s003740000209"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.2165/00003495-200565170-00003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039299286", 
          "https://doi.org/10.2165/00003495-200565170-00003"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02035244", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049909229", 
          "https://doi.org/10.1007/bf02035244"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2011-04-13", 
    "datePublishedReg": "2011-04-13", 
    "description": "Humic acids are known for their overall positive health and productivity effects in animal feeding trials and, controversially, as an aetiological factor of cancer. We tried to assess the in vitro effect of humic acids from a selected source in Slovakia when used at recommended prophylactic dosage. We investigated antioxidant properties, enzymatic and non-enzymatic antioxidant defence system in liver mitochondria and cultured cancer cell lines in vitro. We observed a significant decrease in superoxide dismutase activity after humic acids treatment irrespective of dissolving in dimethyl sulphoxide or direct addition to mitochondria suspension in a respiration medium. Activities of other antioxidant enzymes measured, such as glutathione peroxidase and glutathione reductase, showed no significant differences from the control as well as the reduced glutathione content. Percentage of inhibition by humic acids of superoxide radical indicated lower efficacy compared with that of hydroxyl radical. Survival of six different cancer cells lines indicated that only the acute T lymphoblastic leukaemia cell line was sensitive to the tested humic acids. Despite relatively low solubility in aqueous solutions, humic acids from the selected source participated in redox regulation. By recapturing the radicals, humic acids reloaded the antioxidant defensive mechanism. Results from in vitro study conducted with humic acids from the natural source showed potential of these substances as promising immunity enhancing agents.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/s11626-011-9405-8", 
    "inLanguage": "en", 
    "isAccessibleForFree": false, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.4365284", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1312212", 
        "issn": [
          "1071-2690", 
          "1543-706X"
        ], 
        "name": "In Vitro Cellular & Developmental Biology - Animal", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "5-6", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "47"
      }
    ], 
    "keywords": [
      "cancer cell lines", 
      "cell lines", 
      "lymphoblastic leukemia cell line", 
      "reduced glutathione content", 
      "antioxidant defensive mechanism", 
      "cultured cancer cell lines", 
      "superoxide dismutase activity", 
      "prophylactic dosage", 
      "aetiological factors", 
      "antioxidant defense system", 
      "percentage of inhibition", 
      "leukemia cell lines", 
      "different cancer cell lines", 
      "glutathione peroxidase", 
      "low efficacy", 
      "dismutase activity", 
      "significant decrease", 
      "positive health", 
      "glutathione content", 
      "significant differences", 
      "antioxidant enzymes", 
      "non-enzymatic antioxidant defense system", 
      "feeding trial", 
      "antioxidant properties", 
      "glutathione reductase", 
      "animal feeding trials", 
      "defense system", 
      "respiration medium", 
      "liver mitochondria", 
      "defensive mechanisms", 
      "cancer", 
      "immunity", 
      "trials", 
      "efficacy", 
      "survival", 
      "treatment", 
      "mitochondria suspension", 
      "acid", 
      "acid treatment", 
      "activity", 
      "effect", 
      "inhibition", 
      "health", 
      "dosage", 
      "agents", 
      "percentage", 
      "redox regulation", 
      "lines", 
      "direct addition", 
      "factors", 
      "decrease", 
      "peroxidase", 
      "differences", 
      "dimethyl sulphoxide", 
      "control", 
      "natural sources", 
      "study", 
      "substances", 
      "regulation", 
      "mitochondria", 
      "enzyme", 
      "mechanism", 
      "reductase", 
      "addition", 
      "potential", 
      "sulphoxide", 
      "low solubility", 
      "results", 
      "radicals", 
      "source", 
      "humic acid treatment", 
      "suspension", 
      "medium", 
      "content", 
      "system", 
      "Slovakia", 
      "humic acid", 
      "solubility", 
      "hydroxyl", 
      "properties", 
      "aqueous solution", 
      "solution", 
      "productivity effects", 
      "overall positive health"
    ], 
    "name": "Effects of humic acids in vitro", 
    "pagination": "376-382", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1019151387"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s11626-011-9405-8"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "21487922"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s11626-011-9405-8", 
      "https://app.dimensions.ai/details/publication/pub.1019151387"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2021-12-01T19:25", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20211201/entities/gbq_results/article/article_541.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/s11626-011-9405-8"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s11626-011-9405-8'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s11626-011-9405-8'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s11626-011-9405-8'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s11626-011-9405-8'


 

This table displays all metadata directly associated to this object as RDF triples.

242 TRIPLES      22 PREDICATES      126 URIs      114 LITERALS      19 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s11626-011-9405-8 schema:about N1845f1ee42a042c39ba9b8d8dedfc4cd
2 N1a707b3073274ef492af24864043bf6c
3 N217c995fadcc4a54b8969b680383f411
4 N39d04269ccec4c01867ede993997dd18
5 N5d556f07ff4b4c9197ec2eb1be34b01d
6 N620da20a8b874fb4bf1654adc9dedcaa
7 N8115e2378e1244ae9f68a929b05bcff9
8 N98d2ada91a294f73944c428e358f183c
9 Nae0b59cbed244437bd77c36b19e6d593
10 Nb98eb37c4e5740a0ae1dbac788e463cf
11 Ncf350fcf4226433fafd50604c8e22577
12 Ncfa30b2dc9784af5adb9dec4cd699216
13 anzsrc-for:11
14 anzsrc-for:1115
15 schema:author Nc0c8d45856cd4e4480bc1836eca1ac1d
16 schema:citation sg:pub.10.1007/bf02035244
17 sg:pub.10.1007/s003740000209
18 sg:pub.10.1023/b:ifla.0000039563.90066.5d
19 sg:pub.10.2165/00003495-200565170-00003
20 schema:datePublished 2011-04-13
21 schema:datePublishedReg 2011-04-13
22 schema:description Humic acids are known for their overall positive health and productivity effects in animal feeding trials and, controversially, as an aetiological factor of cancer. We tried to assess the in vitro effect of humic acids from a selected source in Slovakia when used at recommended prophylactic dosage. We investigated antioxidant properties, enzymatic and non-enzymatic antioxidant defence system in liver mitochondria and cultured cancer cell lines in vitro. We observed a significant decrease in superoxide dismutase activity after humic acids treatment irrespective of dissolving in dimethyl sulphoxide or direct addition to mitochondria suspension in a respiration medium. Activities of other antioxidant enzymes measured, such as glutathione peroxidase and glutathione reductase, showed no significant differences from the control as well as the reduced glutathione content. Percentage of inhibition by humic acids of superoxide radical indicated lower efficacy compared with that of hydroxyl radical. Survival of six different cancer cells lines indicated that only the acute T lymphoblastic leukaemia cell line was sensitive to the tested humic acids. Despite relatively low solubility in aqueous solutions, humic acids from the selected source participated in redox regulation. By recapturing the radicals, humic acids reloaded the antioxidant defensive mechanism. Results from in vitro study conducted with humic acids from the natural source showed potential of these substances as promising immunity enhancing agents.
23 schema:genre article
24 schema:inLanguage en
25 schema:isAccessibleForFree false
26 schema:isPartOf N2259f98fd9f842d68fd62b22645682d5
27 N2f273f3db0e441b49fea1e799265a67a
28 sg:journal.1312212
29 schema:keywords Slovakia
30 acid
31 acid treatment
32 activity
33 addition
34 aetiological factors
35 agents
36 animal feeding trials
37 antioxidant defense system
38 antioxidant defensive mechanism
39 antioxidant enzymes
40 antioxidant properties
41 aqueous solution
42 cancer
43 cancer cell lines
44 cell lines
45 content
46 control
47 cultured cancer cell lines
48 decrease
49 defense system
50 defensive mechanisms
51 differences
52 different cancer cell lines
53 dimethyl sulphoxide
54 direct addition
55 dismutase activity
56 dosage
57 effect
58 efficacy
59 enzyme
60 factors
61 feeding trial
62 glutathione content
63 glutathione peroxidase
64 glutathione reductase
65 health
66 humic acid
67 humic acid treatment
68 hydroxyl
69 immunity
70 inhibition
71 leukemia cell lines
72 lines
73 liver mitochondria
74 low efficacy
75 low solubility
76 lymphoblastic leukemia cell line
77 mechanism
78 medium
79 mitochondria
80 mitochondria suspension
81 natural sources
82 non-enzymatic antioxidant defense system
83 overall positive health
84 percentage
85 percentage of inhibition
86 peroxidase
87 positive health
88 potential
89 productivity effects
90 properties
91 prophylactic dosage
92 radicals
93 redox regulation
94 reduced glutathione content
95 reductase
96 regulation
97 respiration medium
98 results
99 significant decrease
100 significant differences
101 solubility
102 solution
103 source
104 study
105 substances
106 sulphoxide
107 superoxide dismutase activity
108 survival
109 suspension
110 system
111 treatment
112 trials
113 schema:name Effects of humic acids in vitro
114 schema:pagination 376-382
115 schema:productId N22da116a75ef4f9ea2740959e7657b03
116 N8629b98ae5e74540817f051b3e555ce0
117 Ne9c1db123a224db390f6a9df36da3c9c
118 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019151387
119 https://doi.org/10.1007/s11626-011-9405-8
120 schema:sdDatePublished 2021-12-01T19:25
121 schema:sdLicense https://scigraph.springernature.com/explorer/license/
122 schema:sdPublisher Nb5ecf3722ceb4a34a383eade0cac3e26
123 schema:url https://doi.org/10.1007/s11626-011-9405-8
124 sgo:license sg:explorer/license/
125 sgo:sdDataset articles
126 rdf:type schema:ScholarlyArticle
127 N1845f1ee42a042c39ba9b8d8dedfc4cd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
128 schema:name Humic Substances
129 rdf:type schema:DefinedTerm
130 N188a14fdf13e4b7cbc8a3149b156f3a9 rdf:first sg:person.01143661542.87
131 rdf:rest rdf:nil
132 N1a707b3073274ef492af24864043bf6c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
133 schema:name Dose-Response Relationship, Drug
134 rdf:type schema:DefinedTerm
135 N217c995fadcc4a54b8969b680383f411 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
136 schema:name Rats, Wistar
137 rdf:type schema:DefinedTerm
138 N2259f98fd9f842d68fd62b22645682d5 schema:issueNumber 5-6
139 rdf:type schema:PublicationIssue
140 N22da116a75ef4f9ea2740959e7657b03 schema:name doi
141 schema:value 10.1007/s11626-011-9405-8
142 rdf:type schema:PropertyValue
143 N2f273f3db0e441b49fea1e799265a67a schema:volumeNumber 47
144 rdf:type schema:PublicationVolume
145 N39d04269ccec4c01867ede993997dd18 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
146 schema:name Antioxidants
147 rdf:type schema:DefinedTerm
148 N51a3df30f1e24805aef90ae1f070c187 rdf:first sg:person.01331762451.62
149 rdf:rest N188a14fdf13e4b7cbc8a3149b156f3a9
150 N5d556f07ff4b4c9197ec2eb1be34b01d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
151 schema:name Rats
152 rdf:type schema:DefinedTerm
153 N620da20a8b874fb4bf1654adc9dedcaa schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
154 schema:name Hydroxyl Radical
155 rdf:type schema:DefinedTerm
156 N6dc478f3875843c488296e79fc8dc070 rdf:first sg:person.0767754015.15
157 rdf:rest N51a3df30f1e24805aef90ae1f070c187
158 N70e366397e934b00bb8165006ba0940e rdf:first sg:person.01112765170.21
159 rdf:rest N6dc478f3875843c488296e79fc8dc070
160 N8115e2378e1244ae9f68a929b05bcff9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
161 schema:name HeLa Cells
162 rdf:type schema:DefinedTerm
163 N8629b98ae5e74540817f051b3e555ce0 schema:name pubmed_id
164 schema:value 21487922
165 rdf:type schema:PropertyValue
166 N98d2ada91a294f73944c428e358f183c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
167 schema:name Humans
168 rdf:type schema:DefinedTerm
169 Nae0b59cbed244437bd77c36b19e6d593 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
170 schema:name Animals
171 rdf:type schema:DefinedTerm
172 Nb5ecf3722ceb4a34a383eade0cac3e26 schema:name Springer Nature - SN SciGraph project
173 rdf:type schema:Organization
174 Nb98eb37c4e5740a0ae1dbac788e463cf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
175 schema:name Tumor Cells, Cultured
176 rdf:type schema:DefinedTerm
177 Nc0c8d45856cd4e4480bc1836eca1ac1d rdf:first sg:person.0761317742.71
178 rdf:rest N70e366397e934b00bb8165006ba0940e
179 Ncf350fcf4226433fafd50604c8e22577 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
180 schema:name Superoxide Dismutase
181 rdf:type schema:DefinedTerm
182 Ncfa30b2dc9784af5adb9dec4cd699216 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
183 schema:name Male
184 rdf:type schema:DefinedTerm
185 Ne9c1db123a224db390f6a9df36da3c9c schema:name dimensions_id
186 schema:value pub.1019151387
187 rdf:type schema:PropertyValue
188 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
189 schema:name Medical and Health Sciences
190 rdf:type schema:DefinedTerm
191 anzsrc-for:1115 schema:inDefinedTermSet anzsrc-for:
192 schema:name Pharmacology and Pharmaceutical Sciences
193 rdf:type schema:DefinedTerm
194 sg:grant.4365284 http://pending.schema.org/fundedItem sg:pub.10.1007/s11626-011-9405-8
195 rdf:type schema:MonetaryGrant
196 sg:journal.1312212 schema:issn 1071-2690
197 1543-706X
198 schema:name In Vitro Cellular & Developmental Biology - Animal
199 schema:publisher Springer Nature
200 rdf:type schema:Periodical
201 sg:person.01112765170.21 schema:affiliation grid-institutes:grid.11175.33
202 schema:familyName Veliká
203 schema:givenName Beáta
204 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01112765170.21
205 rdf:type schema:Person
206 sg:person.01143661542.87 schema:affiliation grid-institutes:grid.11175.33
207 schema:familyName Vaško
208 schema:givenName Ladislav
209 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01143661542.87
210 rdf:type schema:Person
211 sg:person.01331762451.62 schema:affiliation grid-institutes:grid.11175.33
212 schema:familyName Kron
213 schema:givenName Ivan
214 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01331762451.62
215 rdf:type schema:Person
216 sg:person.0761317742.71 schema:affiliation grid-institutes:grid.11175.33
217 schema:familyName Vašková
218 schema:givenName Janka
219 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0761317742.71
220 rdf:type schema:Person
221 sg:person.0767754015.15 schema:affiliation grid-institutes:grid.11175.33
222 schema:familyName Pilátová
223 schema:givenName Martina
224 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0767754015.15
225 rdf:type schema:Person
226 sg:pub.10.1007/bf02035244 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049909229
227 https://doi.org/10.1007/bf02035244
228 rdf:type schema:CreativeWork
229 sg:pub.10.1007/s003740000209 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051410876
230 https://doi.org/10.1007/s003740000209
231 rdf:type schema:CreativeWork
232 sg:pub.10.1023/b:ifla.0000039563.90066.5d schema:sameAs https://app.dimensions.ai/details/publication/pub.1011512555
233 https://doi.org/10.1023/b:ifla.0000039563.90066.5d
234 rdf:type schema:CreativeWork
235 sg:pub.10.2165/00003495-200565170-00003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039299286
236 https://doi.org/10.2165/00003495-200565170-00003
237 rdf:type schema:CreativeWork
238 grid-institutes:grid.11175.33 schema:alternateName Department of Medical Chemistry, Biochemistry and Clinical Biochemistry, Faculty of Medicine, Pavol Jozef Šafárik University in Košice, Tr. SNP 1, 040 11, Košice, Slovak Republic
239 Department of Pharmacology, Faculty of Medicine, Pavol Jozef Šafárik University in Košice, Košice, Slovak Republic
240 schema:name Department of Medical Chemistry, Biochemistry and Clinical Biochemistry, Faculty of Medicine, Pavol Jozef Šafárik University in Košice, Tr. SNP 1, 040 11, Košice, Slovak Republic
241 Department of Pharmacology, Faculty of Medicine, Pavol Jozef Šafárik University in Košice, Košice, Slovak Republic
242 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...