Effects of humic acids in vitro View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2011-04-13

AUTHORS

Janka Vašková, Beáta Veliká, Martina Pilátová, Ivan Kron, Ladislav Vaško

ABSTRACT

Humic acids are known for their overall positive health and productivity effects in animal feeding trials and, controversially, as an aetiological factor of cancer. We tried to assess the in vitro effect of humic acids from a selected source in Slovakia when used at recommended prophylactic dosage. We investigated antioxidant properties, enzymatic and non-enzymatic antioxidant defence system in liver mitochondria and cultured cancer cell lines in vitro. We observed a significant decrease in superoxide dismutase activity after humic acids treatment irrespective of dissolving in dimethyl sulphoxide or direct addition to mitochondria suspension in a respiration medium. Activities of other antioxidant enzymes measured, such as glutathione peroxidase and glutathione reductase, showed no significant differences from the control as well as the reduced glutathione content. Percentage of inhibition by humic acids of superoxide radical indicated lower efficacy compared with that of hydroxyl radical. Survival of six different cancer cells lines indicated that only the acute T lymphoblastic leukaemia cell line was sensitive to the tested humic acids. Despite relatively low solubility in aqueous solutions, humic acids from the selected source participated in redox regulation. By recapturing the radicals, humic acids reloaded the antioxidant defensive mechanism. Results from in vitro study conducted with humic acids from the natural source showed potential of these substances as promising immunity enhancing agents. More... »

PAGES

376-382

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11626-011-9405-8

DOI

http://dx.doi.org/10.1007/s11626-011-9405-8

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1019151387

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/21487922


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1115", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Pharmacology and Pharmaceutical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antioxidants", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Dose-Response Relationship, Drug", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "HeLa Cells", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humic Substances", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hydroxyl Radical", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rats", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rats, Wistar", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Superoxide Dismutase", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Tumor Cells, Cultured", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Medical Chemistry, Biochemistry and Clinical Biochemistry, Faculty of Medicine, Pavol Jozef \u0160af\u00e1rik University in Ko\u0161ice, Tr. SNP 1, 040 11, Ko\u0161ice, Slovak Republic", 
          "id": "http://www.grid.ac/institutes/grid.11175.33", 
          "name": [
            "Department of Medical Chemistry, Biochemistry and Clinical Biochemistry, Faculty of Medicine, Pavol Jozef \u0160af\u00e1rik University in Ko\u0161ice, Tr. SNP 1, 040 11, Ko\u0161ice, Slovak Republic"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Va\u0161kov\u00e1", 
        "givenName": "Janka", 
        "id": "sg:person.0761317742.71", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0761317742.71"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Medical Chemistry, Biochemistry and Clinical Biochemistry, Faculty of Medicine, Pavol Jozef \u0160af\u00e1rik University in Ko\u0161ice, Tr. SNP 1, 040 11, Ko\u0161ice, Slovak Republic", 
          "id": "http://www.grid.ac/institutes/grid.11175.33", 
          "name": [
            "Department of Medical Chemistry, Biochemistry and Clinical Biochemistry, Faculty of Medicine, Pavol Jozef \u0160af\u00e1rik University in Ko\u0161ice, Tr. SNP 1, 040 11, Ko\u0161ice, Slovak Republic"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Velik\u00e1", 
        "givenName": "Be\u00e1ta", 
        "id": "sg:person.01112765170.21", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01112765170.21"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Pharmacology, Faculty of Medicine, Pavol Jozef \u0160af\u00e1rik University in Ko\u0161ice, Ko\u0161ice, Slovak Republic", 
          "id": "http://www.grid.ac/institutes/grid.11175.33", 
          "name": [
            "Department of Pharmacology, Faculty of Medicine, Pavol Jozef \u0160af\u00e1rik University in Ko\u0161ice, Ko\u0161ice, Slovak Republic"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pil\u00e1tov\u00e1", 
        "givenName": "Martina", 
        "id": "sg:person.0767754015.15", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0767754015.15"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Medical Chemistry, Biochemistry and Clinical Biochemistry, Faculty of Medicine, Pavol Jozef \u0160af\u00e1rik University in Ko\u0161ice, Tr. SNP 1, 040 11, Ko\u0161ice, Slovak Republic", 
          "id": "http://www.grid.ac/institutes/grid.11175.33", 
          "name": [
            "Department of Medical Chemistry, Biochemistry and Clinical Biochemistry, Faculty of Medicine, Pavol Jozef \u0160af\u00e1rik University in Ko\u0161ice, Tr. SNP 1, 040 11, Ko\u0161ice, Slovak Republic"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kron", 
        "givenName": "Ivan", 
        "id": "sg:person.01331762451.62", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01331762451.62"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Medical Chemistry, Biochemistry and Clinical Biochemistry, Faculty of Medicine, Pavol Jozef \u0160af\u00e1rik University in Ko\u0161ice, Tr. SNP 1, 040 11, Ko\u0161ice, Slovak Republic", 
          "id": "http://www.grid.ac/institutes/grid.11175.33", 
          "name": [
            "Department of Medical Chemistry, Biochemistry and Clinical Biochemistry, Faculty of Medicine, Pavol Jozef \u0160af\u00e1rik University in Ko\u0161ice, Tr. SNP 1, 040 11, Ko\u0161ice, Slovak Republic"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Va\u0161ko", 
        "givenName": "Ladislav", 
        "id": "sg:person.01143661542.87", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01143661542.87"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/s003740000209", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051410876", 
          "https://doi.org/10.1007/s003740000209"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02035244", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049909229", 
          "https://doi.org/10.1007/bf02035244"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1023/b:ifla.0000039563.90066.5d", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011512555", 
          "https://doi.org/10.1023/b:ifla.0000039563.90066.5d"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.2165/00003495-200565170-00003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039299286", 
          "https://doi.org/10.2165/00003495-200565170-00003"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2011-04-13", 
    "datePublishedReg": "2011-04-13", 
    "description": "Humic acids are known for their overall positive health and productivity effects in animal feeding trials and, controversially, as an aetiological factor of cancer. We tried to assess the in vitro effect of humic acids from a selected source in Slovakia when used at recommended prophylactic dosage. We investigated antioxidant properties, enzymatic and non-enzymatic antioxidant defence system in liver mitochondria and cultured cancer cell lines in vitro. We observed a significant decrease in superoxide dismutase activity after humic acids treatment irrespective of dissolving in dimethyl sulphoxide or direct addition to mitochondria suspension in a respiration medium. Activities of other antioxidant enzymes measured, such as glutathione peroxidase and glutathione reductase, showed no significant differences from the control as well as the reduced glutathione content. Percentage of inhibition by humic acids of superoxide radical indicated lower efficacy compared with that of hydroxyl radical. Survival of six different cancer cells lines indicated that only the acute T lymphoblastic leukaemia cell line was sensitive to the tested humic acids. Despite relatively low solubility in aqueous solutions, humic acids from the selected source participated in redox regulation. By recapturing the radicals, humic acids reloaded the antioxidant defensive mechanism. Results from in vitro study conducted with humic acids from the natural source showed potential of these substances as promising immunity enhancing agents.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/s11626-011-9405-8", 
    "inLanguage": "en", 
    "isAccessibleForFree": false, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.4365284", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1312212", 
        "issn": [
          "1071-2690", 
          "1543-706X"
        ], 
        "name": "In Vitro Cellular & Developmental Biology - Animal", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "5-6", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "47"
      }
    ], 
    "keywords": [
      "cancer cell lines", 
      "cell lines", 
      "lymphoblastic leukemia cell line", 
      "reduced glutathione content", 
      "antioxidant defensive mechanism", 
      "cultured cancer cell lines", 
      "superoxide dismutase activity", 
      "prophylactic dosage", 
      "aetiological factors", 
      "antioxidant defense system", 
      "percentage of inhibition", 
      "leukemia cell lines", 
      "different cancer cell lines", 
      "glutathione peroxidase", 
      "low efficacy", 
      "dismutase activity", 
      "significant decrease", 
      "positive health", 
      "glutathione content", 
      "significant differences", 
      "antioxidant enzymes", 
      "non-enzymatic antioxidant defense system", 
      "feeding trial", 
      "antioxidant properties", 
      "glutathione reductase", 
      "animal feeding trials", 
      "defense system", 
      "respiration medium", 
      "liver mitochondria", 
      "defensive mechanisms", 
      "cancer", 
      "immunity", 
      "trials", 
      "efficacy", 
      "survival", 
      "treatment", 
      "mitochondria suspension", 
      "acid", 
      "acid treatment", 
      "activity", 
      "effect", 
      "inhibition", 
      "health", 
      "dosage", 
      "agents", 
      "percentage", 
      "redox regulation", 
      "lines", 
      "direct addition", 
      "factors", 
      "decrease", 
      "peroxidase", 
      "differences", 
      "dimethyl sulphoxide", 
      "control", 
      "natural sources", 
      "study", 
      "substances", 
      "regulation", 
      "mitochondria", 
      "enzyme", 
      "mechanism", 
      "reductase", 
      "addition", 
      "potential", 
      "sulphoxide", 
      "low solubility", 
      "results", 
      "radicals", 
      "source", 
      "humic acid treatment", 
      "suspension", 
      "medium", 
      "content", 
      "system", 
      "Slovakia", 
      "humic acid", 
      "solubility", 
      "hydroxyl", 
      "properties", 
      "aqueous solution", 
      "solution", 
      "productivity effects", 
      "overall positive health"
    ], 
    "name": "Effects of humic acids in vitro", 
    "pagination": "376-382", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1019151387"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s11626-011-9405-8"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "21487922"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s11626-011-9405-8", 
      "https://app.dimensions.ai/details/publication/pub.1019151387"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-01-01T18:26", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220101/entities/gbq_results/article/article_553.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/s11626-011-9405-8"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s11626-011-9405-8'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s11626-011-9405-8'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s11626-011-9405-8'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s11626-011-9405-8'


 

This table displays all metadata directly associated to this object as RDF triples.

242 TRIPLES      22 PREDICATES      126 URIs      114 LITERALS      19 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s11626-011-9405-8 schema:about N06963041b0524825b117cc21da16bf8f
2 N06fdc4b2cb0545c5a64e758b457fb29f
3 N1e794b578a7d41b397b8ec97648d9852
4 N40e1bb4dbe434ac5a2e160c96fd96949
5 N42c09e30e536488f8c05b9cc8d714e2a
6 N56bb96d9bf8f4e9aac99e137bb6a2afb
7 N5e2c0eceea074a7a977f0011126a59a0
8 N7ff93967ad67482490cee6106d528263
9 N9c4be0ef6ad24cff97ea8debba2e5945
10 N9dbab1874226476793ca52519433804e
11 Nbc1cdea04492408595337cf6b071aee4
12 Nea9fe3abe02248cc85137154cd679004
13 anzsrc-for:11
14 anzsrc-for:1115
15 schema:author Nd07c31f46c194631a35908e1495b1959
16 schema:citation sg:pub.10.1007/bf02035244
17 sg:pub.10.1007/s003740000209
18 sg:pub.10.1023/b:ifla.0000039563.90066.5d
19 sg:pub.10.2165/00003495-200565170-00003
20 schema:datePublished 2011-04-13
21 schema:datePublishedReg 2011-04-13
22 schema:description Humic acids are known for their overall positive health and productivity effects in animal feeding trials and, controversially, as an aetiological factor of cancer. We tried to assess the in vitro effect of humic acids from a selected source in Slovakia when used at recommended prophylactic dosage. We investigated antioxidant properties, enzymatic and non-enzymatic antioxidant defence system in liver mitochondria and cultured cancer cell lines in vitro. We observed a significant decrease in superoxide dismutase activity after humic acids treatment irrespective of dissolving in dimethyl sulphoxide or direct addition to mitochondria suspension in a respiration medium. Activities of other antioxidant enzymes measured, such as glutathione peroxidase and glutathione reductase, showed no significant differences from the control as well as the reduced glutathione content. Percentage of inhibition by humic acids of superoxide radical indicated lower efficacy compared with that of hydroxyl radical. Survival of six different cancer cells lines indicated that only the acute T lymphoblastic leukaemia cell line was sensitive to the tested humic acids. Despite relatively low solubility in aqueous solutions, humic acids from the selected source participated in redox regulation. By recapturing the radicals, humic acids reloaded the antioxidant defensive mechanism. Results from in vitro study conducted with humic acids from the natural source showed potential of these substances as promising immunity enhancing agents.
23 schema:genre article
24 schema:inLanguage en
25 schema:isAccessibleForFree false
26 schema:isPartOf N33cafdd756ae4aafa58a3864b471f441
27 N8963219a9c1941dd859c03216685a85a
28 sg:journal.1312212
29 schema:keywords Slovakia
30 acid
31 acid treatment
32 activity
33 addition
34 aetiological factors
35 agents
36 animal feeding trials
37 antioxidant defense system
38 antioxidant defensive mechanism
39 antioxidant enzymes
40 antioxidant properties
41 aqueous solution
42 cancer
43 cancer cell lines
44 cell lines
45 content
46 control
47 cultured cancer cell lines
48 decrease
49 defense system
50 defensive mechanisms
51 differences
52 different cancer cell lines
53 dimethyl sulphoxide
54 direct addition
55 dismutase activity
56 dosage
57 effect
58 efficacy
59 enzyme
60 factors
61 feeding trial
62 glutathione content
63 glutathione peroxidase
64 glutathione reductase
65 health
66 humic acid
67 humic acid treatment
68 hydroxyl
69 immunity
70 inhibition
71 leukemia cell lines
72 lines
73 liver mitochondria
74 low efficacy
75 low solubility
76 lymphoblastic leukemia cell line
77 mechanism
78 medium
79 mitochondria
80 mitochondria suspension
81 natural sources
82 non-enzymatic antioxidant defense system
83 overall positive health
84 percentage
85 percentage of inhibition
86 peroxidase
87 positive health
88 potential
89 productivity effects
90 properties
91 prophylactic dosage
92 radicals
93 redox regulation
94 reduced glutathione content
95 reductase
96 regulation
97 respiration medium
98 results
99 significant decrease
100 significant differences
101 solubility
102 solution
103 source
104 study
105 substances
106 sulphoxide
107 superoxide dismutase activity
108 survival
109 suspension
110 system
111 treatment
112 trials
113 schema:name Effects of humic acids in vitro
114 schema:pagination 376-382
115 schema:productId N263cefd581774a9fb339fbdb6d080f39
116 N28692662149e43599247abe154706a76
117 Nb6f368a3969145e59cb6e54c0c6026bc
118 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019151387
119 https://doi.org/10.1007/s11626-011-9405-8
120 schema:sdDatePublished 2022-01-01T18:26
121 schema:sdLicense https://scigraph.springernature.com/explorer/license/
122 schema:sdPublisher N8bc0211de31442699e2d847c55032cad
123 schema:url https://doi.org/10.1007/s11626-011-9405-8
124 sgo:license sg:explorer/license/
125 sgo:sdDataset articles
126 rdf:type schema:ScholarlyArticle
127 N06963041b0524825b117cc21da16bf8f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
128 schema:name Antioxidants
129 rdf:type schema:DefinedTerm
130 N06fdc4b2cb0545c5a64e758b457fb29f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
131 schema:name Rats, Wistar
132 rdf:type schema:DefinedTerm
133 N10911791dbe049e680d6c462cc0714e5 rdf:first sg:person.0767754015.15
134 rdf:rest Na9a14218f7304780aed9111a0c762072
135 N1e794b578a7d41b397b8ec97648d9852 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
136 schema:name Humic Substances
137 rdf:type schema:DefinedTerm
138 N263cefd581774a9fb339fbdb6d080f39 schema:name dimensions_id
139 schema:value pub.1019151387
140 rdf:type schema:PropertyValue
141 N28692662149e43599247abe154706a76 schema:name doi
142 schema:value 10.1007/s11626-011-9405-8
143 rdf:type schema:PropertyValue
144 N33cafdd756ae4aafa58a3864b471f441 schema:volumeNumber 47
145 rdf:type schema:PublicationVolume
146 N40e1bb4dbe434ac5a2e160c96fd96949 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
147 schema:name Rats
148 rdf:type schema:DefinedTerm
149 N42c09e30e536488f8c05b9cc8d714e2a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
150 schema:name Humans
151 rdf:type schema:DefinedTerm
152 N56bb96d9bf8f4e9aac99e137bb6a2afb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
153 schema:name Dose-Response Relationship, Drug
154 rdf:type schema:DefinedTerm
155 N5e2c0eceea074a7a977f0011126a59a0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
156 schema:name Hydroxyl Radical
157 rdf:type schema:DefinedTerm
158 N7ff93967ad67482490cee6106d528263 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
159 schema:name Tumor Cells, Cultured
160 rdf:type schema:DefinedTerm
161 N8963219a9c1941dd859c03216685a85a schema:issueNumber 5-6
162 rdf:type schema:PublicationIssue
163 N8bbd476ee92b4bbd8b73cf12f135ff6e rdf:first sg:person.01143661542.87
164 rdf:rest rdf:nil
165 N8bc0211de31442699e2d847c55032cad schema:name Springer Nature - SN SciGraph project
166 rdf:type schema:Organization
167 N9c4be0ef6ad24cff97ea8debba2e5945 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
168 schema:name HeLa Cells
169 rdf:type schema:DefinedTerm
170 N9dbab1874226476793ca52519433804e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
171 schema:name Animals
172 rdf:type schema:DefinedTerm
173 Na9a14218f7304780aed9111a0c762072 rdf:first sg:person.01331762451.62
174 rdf:rest N8bbd476ee92b4bbd8b73cf12f135ff6e
175 Nb6f368a3969145e59cb6e54c0c6026bc schema:name pubmed_id
176 schema:value 21487922
177 rdf:type schema:PropertyValue
178 Nbc1cdea04492408595337cf6b071aee4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
179 schema:name Male
180 rdf:type schema:DefinedTerm
181 Nd07c31f46c194631a35908e1495b1959 rdf:first sg:person.0761317742.71
182 rdf:rest Nd32cee8e86954432bee09067f68b05e8
183 Nd32cee8e86954432bee09067f68b05e8 rdf:first sg:person.01112765170.21
184 rdf:rest N10911791dbe049e680d6c462cc0714e5
185 Nea9fe3abe02248cc85137154cd679004 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
186 schema:name Superoxide Dismutase
187 rdf:type schema:DefinedTerm
188 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
189 schema:name Medical and Health Sciences
190 rdf:type schema:DefinedTerm
191 anzsrc-for:1115 schema:inDefinedTermSet anzsrc-for:
192 schema:name Pharmacology and Pharmaceutical Sciences
193 rdf:type schema:DefinedTerm
194 sg:grant.4365284 http://pending.schema.org/fundedItem sg:pub.10.1007/s11626-011-9405-8
195 rdf:type schema:MonetaryGrant
196 sg:journal.1312212 schema:issn 1071-2690
197 1543-706X
198 schema:name In Vitro Cellular & Developmental Biology - Animal
199 schema:publisher Springer Nature
200 rdf:type schema:Periodical
201 sg:person.01112765170.21 schema:affiliation grid-institutes:grid.11175.33
202 schema:familyName Veliká
203 schema:givenName Beáta
204 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01112765170.21
205 rdf:type schema:Person
206 sg:person.01143661542.87 schema:affiliation grid-institutes:grid.11175.33
207 schema:familyName Vaško
208 schema:givenName Ladislav
209 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01143661542.87
210 rdf:type schema:Person
211 sg:person.01331762451.62 schema:affiliation grid-institutes:grid.11175.33
212 schema:familyName Kron
213 schema:givenName Ivan
214 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01331762451.62
215 rdf:type schema:Person
216 sg:person.0761317742.71 schema:affiliation grid-institutes:grid.11175.33
217 schema:familyName Vašková
218 schema:givenName Janka
219 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0761317742.71
220 rdf:type schema:Person
221 sg:person.0767754015.15 schema:affiliation grid-institutes:grid.11175.33
222 schema:familyName Pilátová
223 schema:givenName Martina
224 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0767754015.15
225 rdf:type schema:Person
226 sg:pub.10.1007/bf02035244 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049909229
227 https://doi.org/10.1007/bf02035244
228 rdf:type schema:CreativeWork
229 sg:pub.10.1007/s003740000209 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051410876
230 https://doi.org/10.1007/s003740000209
231 rdf:type schema:CreativeWork
232 sg:pub.10.1023/b:ifla.0000039563.90066.5d schema:sameAs https://app.dimensions.ai/details/publication/pub.1011512555
233 https://doi.org/10.1023/b:ifla.0000039563.90066.5d
234 rdf:type schema:CreativeWork
235 sg:pub.10.2165/00003495-200565170-00003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039299286
236 https://doi.org/10.2165/00003495-200565170-00003
237 rdf:type schema:CreativeWork
238 grid-institutes:grid.11175.33 schema:alternateName Department of Medical Chemistry, Biochemistry and Clinical Biochemistry, Faculty of Medicine, Pavol Jozef Šafárik University in Košice, Tr. SNP 1, 040 11, Košice, Slovak Republic
239 Department of Pharmacology, Faculty of Medicine, Pavol Jozef Šafárik University in Košice, Košice, Slovak Republic
240 schema:name Department of Medical Chemistry, Biochemistry and Clinical Biochemistry, Faculty of Medicine, Pavol Jozef Šafárik University in Košice, Tr. SNP 1, 040 11, Košice, Slovak Republic
241 Department of Pharmacology, Faculty of Medicine, Pavol Jozef Šafárik University in Košice, Košice, Slovak Republic
242 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...