The Influence of Age on Complications and Overall Survival After Ivor Lewis Totally Minimally Invasive Esophagectomy View Full Text


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Article Info

DATE

2018-12-18

AUTHORS

Nikolaj S. Baranov, Frans van Workum, Jolijn van der Maas, Ewout Kouwenhoven, Marc van Det, Frits J. H. van den Wildenberg, Fatih Polat, Grard A. P. Nieuwenhuijzen, Misha D. P. Luyer, Camiel Rosman

ABSTRACT

BACKGROUND: The number of elderly patients suffering from esophageal cancer is increasing, due to an increasing incidence of esophageal cancer and increasing life expectancy. However, the effect of age on morbidity, mortality, and survival after Ivor Lewis total minimally invasive esophagectomy (TMIE) is not well known. METHODS: A prospectively documented database from December 2010 to June 2017 was analyzed, including all patients who underwent Ivor Lewis TMIE for esophageal cancer in three Dutch high-volume esophageal cancer centers. Patients younger than 75 years (younger group) were compared to patients aged 75 years or older (elderly group). Baseline patient characteristics and perioperative data were included. Surgical complications were graded using the Clavien-Dindo scale. The primary outcome was postoperative complications Clavien-Dindo ≥ 3. Secondary outcome parameters were postoperative complications, in-hospital mortality, 30- and 90-day mortality and survival. RESULTS: Four hundred and forty-six patients were included, 357 in the younger and 89 in the elderly group. No significant differences were recorded regarding baseline patient characteristics. There was no significant difference in complications graded Clavien-Dindo ≥ 3 and overall complications, short-term mortality, and survival. Delirium occurred in 27.0% in the elderly and 11.8% in the younger group (p < 0.001). After correction for baseline comorbidity this difference remained significant (p = 0.001). Median hospital length of stay was 13 days in the elderly and 11 days in the younger group (p = 0.010). CONCLUSIONS: Ivor Lewis TMIE can be safely performed in selected elderly patients without increasing postoperative morbidity and mortality. More... »

PAGES

1-8

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Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11605-018-4062-9

DOI

http://dx.doi.org/10.1007/s11605-018-4062-9

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1110755462

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30565069


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    "description": "BACKGROUND: The number of elderly patients suffering from esophageal cancer is increasing, due to an increasing incidence of esophageal cancer and increasing life expectancy. However, the effect of age on morbidity, mortality, and survival after Ivor Lewis total minimally invasive esophagectomy (TMIE) is not well known.\nMETHODS: A prospectively documented database from December 2010 to June 2017 was analyzed, including all patients who underwent Ivor Lewis TMIE for esophageal cancer in three Dutch high-volume esophageal cancer centers. Patients younger than 75\u00a0years (younger group) were compared to patients aged 75\u00a0years or older (elderly group). Baseline patient characteristics and perioperative data were included. Surgical complications were graded using the Clavien-Dindo scale. The primary outcome was postoperative complications Clavien-Dindo \u2265\u20093. Secondary outcome parameters were postoperative complications, in-hospital mortality, 30- and 90-day mortality and survival.\nRESULTS: Four hundred and forty-six patients were included, 357 in the younger and 89 in the elderly group. No significant differences were recorded regarding baseline patient characteristics. There was no significant difference in complications graded Clavien-Dindo \u2265\u20093 and overall complications, short-term mortality, and survival. Delirium occurred in 27.0% in the elderly and 11.8% in the younger group (p\u2009<\u20090.001). After correction for baseline comorbidity this difference remained significant (p\u2009=\u20090.001). Median hospital length of stay was 13\u00a0days in the elderly and 11\u00a0days in the younger group (p\u2009=\u20090.010).\nCONCLUSIONS: Ivor Lewis TMIE can be safely performed in selected elderly patients without increasing postoperative morbidity and mortality.", 
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RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s11605-018-4062-9'


 

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