Probiotics and Synbiotics Decrease Postoperative Sepsis in Elective Gastrointestinal Surgical Patients: a Meta-Analysis View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2016-06

AUTHORS

Sudha Arumugam, Christine S. M. Lau, Ronald S. Chamberlain

ABSTRACT

BACKGROUND: The health benefits of probiotics and synbiotics are well established in healthy adults, but their role in preventing postoperative sepsis remains controversial. This meta-analysis assesses the impact of probiotics and synbiotics on the incidence of postoperative sepsis in gastrointestinal (GI) surgical patients. METHODS: A comprehensive literature search of all published randomized control trials (RCTs) was conducted using PubMed, Cochrane Central Registry of Controlled Trials, and Google Scholar (1966-2015). Inclusion criteria included RCTs comparing the use of any strain or dose of a specified probiotic/synbiotic with placebo or a "no treatment" control group. The incidence of postoperative sepsis (within 1 month of surgery) and postoperative mortality were analyzed. RESULTS: Fifteen RCTs involving 1201 patients (192 receiving probiotics, 413 receiving synbiotics, and 596 receiving placebo) were analyzed. Overall, probiotic and synbiotic uses significantly reduced the risk of developing postoperative sepsis by 38 % (relative risk (RR) = 0.62, 95 % confidence interval (CI) 0.52-0.74, p < 0.001). CONCLUSIONS: The use of probiotic/synbiotic supplementation is associated with a significant reduction in the risk of developing postoperative sepsis in patients undergoing elective GI surgery. Probiotic/synbiotic supplementation is a valuable adjunct in the care of patients undergoing GI surgery. Additional studies are required to determine the optimal dose and strain of probiotic/synbiotic. More... »

PAGES

1123-1131

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11605-016-3142-y

DOI

http://dx.doi.org/10.1007/s11605-016-3142-y

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1006218742

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/27073082


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Digestive System Surgical Procedures", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Elective Surgical Procedures", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Incidence", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Probiotics", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Randomized Controlled Trials as Topic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sepsis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Synbiotics", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Saint Barnabas Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.416350.5", 
          "name": [
            "Department of Surgery, Saint Barnabas Medical Center, 94 Old Short Hills Road, 07039, Livingston, NJ, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Arumugam", 
        "givenName": "Sudha", 
        "id": "sg:person.0716777523.41", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0716777523.41"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "St. George's University", 
          "id": "https://www.grid.ac/institutes/grid.412748.c", 
          "name": [
            "Department of Surgery, Saint Barnabas Medical Center, 94 Old Short Hills Road, 07039, Livingston, NJ, USA", 
            "Saint George\u2019s University School of Medicine, True Blue, Grenada, West Indies"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lau", 
        "givenName": "Christine S. M.", 
        "id": "sg:person.0705502527.07", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0705502527.07"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "St. George's University", 
          "id": "https://www.grid.ac/institutes/grid.412748.c", 
          "name": [
            "Department of Surgery, Saint Barnabas Medical Center, 94 Old Short Hills Road, 07039, Livingston, NJ, USA", 
            "Department of Surgery, Rutgers University, New Jersey Medical School, Newark, NJ, USA", 
            "Saint George\u2019s University School of Medicine, True Blue, Grenada, West Indies"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chamberlain", 
        "givenName": "Ronald S.", 
        "id": "sg:person.0604062134.84", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0604062134.84"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/s00268-015-3071-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000591097", 
          "https://doi.org/10.1007/s00268-015-3071-z"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.amjsurg.2009.05.025", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003626066"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/j.gastro.2010.10.025", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003809992"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.nut.2013.03.015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003810438"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00134-009-1738-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005074113", 
          "https://doi.org/10.1007/s00134-009-1738-3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00134-009-1738-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005074113", 
          "https://doi.org/10.1007/s00134-009-1738-3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1378/chest.101.6.1644", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006971593"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/10_2008_097", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007630270", 
          "https://doi.org/10.1007/10_2008_097"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/10_2008_097", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007630270", 
          "https://doi.org/10.1007/10_2008_097"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/342912", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008641994"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/bjs.1800800124", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010042783"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00003246-200107000-00002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010433290"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00003246-200107000-00002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010433290"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00003246-200107000-00002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010433290"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/01635581.2015.1004734", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010808778"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3945/ajcn.112.040949", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010945969"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/gut.45.2.223", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011897257"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/bjs.9385", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012342191"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2147/ijgm.s98280", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013035227"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.sla.0000259442.78947.19", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014575291"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.sla.0000259442.78947.19", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014575291"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0b013e3181dcf36e", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015817676"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0b013e3181dcf36e", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015817676"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/sla.0b013e3181dcf36e", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015817676"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00075197-200111000-00019", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017293378"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00075197-200111000-00019", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017293378"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00075197-200111000-00019", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017293378"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/0148607110379813", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020029807"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/archsurg.1990.01410150125024", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021223865"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/ccm.0b013e31819285f0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023778531"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/ccm.0b013e31819285f0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023778531"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/ccm.0b013e31819285f0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023778531"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00007890-200207150-00021", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028816573"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00007890-200207150-00021", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028816573"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.amjsurg.2010.02.013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029508360"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jama.1995.03530040066043", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033259134"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/0148607112452306", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037593123"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0899-9007(02)00811-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039505114"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa022139", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040009693"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2036.2010.04492.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040110233"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2036.2010.04492.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040110233"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/bjs.5705", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044285626"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/bjs.5705", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044285626"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/gut.2003.024620", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045026339"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/bmb/ldh029", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045697556"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1600-6143.2004.00649.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047916686"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s12876-015-0260-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049183764", 
          "https://doi.org/10.1186/s12876-015-0260-z"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s12876-015-0260-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049183764", 
          "https://doi.org/10.1186/s12876-015-0260-z"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00423-004-0536-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050224928", 
          "https://doi.org/10.1007/s00423-004-0536-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00423-004-0536-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050224928", 
          "https://doi.org/10.1007/s00423-004-0536-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ejcn.2009.120", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052950129", 
          "https://doi.org/10.1038/ejcn.2009.120"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3920/bm2014.0079", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1071703831"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.7326/0003-4819-113-3-227", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1073694869"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/ajcn/73.2.361s", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1074750808"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074891166", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/ajcn/87.3.785", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1077617198"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077640574", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077807759", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2016-06", 
    "datePublishedReg": "2016-06-01", 
    "description": "BACKGROUND: The health benefits of probiotics and synbiotics are well established in healthy adults, but their role in preventing postoperative sepsis remains controversial. This meta-analysis assesses the impact of probiotics and synbiotics on the incidence of postoperative sepsis in gastrointestinal (GI) surgical patients.\nMETHODS: A comprehensive literature search of all published randomized control trials (RCTs) was conducted using PubMed, Cochrane Central Registry of Controlled Trials, and Google Scholar (1966-2015). Inclusion criteria included RCTs comparing the use of any strain or dose of a specified probiotic/synbiotic with placebo or a \"no treatment\" control group. The incidence of postoperative sepsis (within 1\u00a0month of surgery) and postoperative mortality were analyzed.\nRESULTS: Fifteen RCTs involving 1201 patients (192 receiving probiotics, 413 receiving synbiotics, and 596 receiving placebo) were analyzed. Overall, probiotic and synbiotic uses significantly reduced the risk of developing postoperative sepsis by 38\u00a0% (relative risk (RR)\u2009=\u20090.62, 95\u00a0% confidence interval (CI) 0.52-0.74, p\u2009<\u20090.001).\nCONCLUSIONS: The use of probiotic/synbiotic supplementation is associated with a significant reduction in the risk of developing postoperative sepsis in patients undergoing elective GI surgery. Probiotic/synbiotic supplementation is a valuable adjunct in the care of patients undergoing GI surgery. Additional studies are required to determine the optimal dose and strain of probiotic/synbiotic.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s11605-016-3142-y", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1116755", 
        "issn": [
          "1091-255X", 
          "1873-4626"
        ], 
        "name": "Journal of Gastrointestinal Surgery", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "6", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "20"
      }
    ], 
    "name": "Probiotics and Synbiotics Decrease Postoperative Sepsis in Elective Gastrointestinal Surgical Patients: a Meta-Analysis", 
    "pagination": "1123-1131", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "1d9f8f0207c5603d92d059bf94d32b4f10a4b32acd0ebdea1da2c5d77bfe82c7"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "27073082"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "9706084"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s11605-016-3142-y"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1006218742"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s11605-016-3142-y", 
      "https://app.dimensions.ai/details/publication/pub.1006218742"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T19:59", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8681_00000520.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007%2Fs11605-016-3142-y"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s11605-016-3142-y'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s11605-016-3142-y'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s11605-016-3142-y'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s11605-016-3142-y'


 

This table displays all metadata directly associated to this object as RDF triples.

249 TRIPLES      21 PREDICATES      79 URIs      29 LITERALS      17 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s11605-016-3142-y schema:about N09f5c71faeaf496d8ff5e72a4d23eda7
2 N3dd63f16411a44d3a367bb61857adb33
3 N712a05f78eac48f6bac20ac99b7a3ec7
4 N73950121210245aeba434895c1765c4d
5 N99d2386912d34a3082435d7e71277bc8
6 Nbac59037d7e14e7ab36f4bb9501b7443
7 Nd1cc53debdb746c6ae5b5de05bf2d0ce
8 Ndf3af50034ff4723a62d161dc5477d2c
9 anzsrc-for:11
10 anzsrc-for:1103
11 schema:author Nb661bde8e3364496bb4907ffef7e12d9
12 schema:citation sg:pub.10.1007/10_2008_097
13 sg:pub.10.1007/s00134-009-1738-3
14 sg:pub.10.1007/s00268-015-3071-z
15 sg:pub.10.1007/s00423-004-0536-1
16 sg:pub.10.1038/ejcn.2009.120
17 sg:pub.10.1186/s12876-015-0260-z
18 https://app.dimensions.ai/details/publication/pub.1074891166
19 https://app.dimensions.ai/details/publication/pub.1077640574
20 https://app.dimensions.ai/details/publication/pub.1077807759
21 https://doi.org/10.1001/archsurg.1990.01410150125024
22 https://doi.org/10.1001/jama.1995.03530040066043
23 https://doi.org/10.1002/bjs.1800800124
24 https://doi.org/10.1002/bjs.5705
25 https://doi.org/10.1002/bjs.9385
26 https://doi.org/10.1016/j.amjsurg.2009.05.025
27 https://doi.org/10.1016/j.amjsurg.2010.02.013
28 https://doi.org/10.1016/j.nut.2013.03.015
29 https://doi.org/10.1016/s0899-9007(02)00811-0
30 https://doi.org/10.1053/j.gastro.2010.10.025
31 https://doi.org/10.1056/nejmoa022139
32 https://doi.org/10.1080/01635581.2015.1004734
33 https://doi.org/10.1086/342912
34 https://doi.org/10.1093/ajcn/73.2.361s
35 https://doi.org/10.1093/ajcn/87.3.785
36 https://doi.org/10.1093/bmb/ldh029
37 https://doi.org/10.1097/00003246-200107000-00002
38 https://doi.org/10.1097/00007890-200207150-00021
39 https://doi.org/10.1097/00075197-200111000-00019
40 https://doi.org/10.1097/01.sla.0000259442.78947.19
41 https://doi.org/10.1097/ccm.0b013e31819285f0
42 https://doi.org/10.1097/sla.0b013e3181dcf36e
43 https://doi.org/10.1111/j.1365-2036.2010.04492.x
44 https://doi.org/10.1111/j.1600-6143.2004.00649.x
45 https://doi.org/10.1136/gut.2003.024620
46 https://doi.org/10.1136/gut.45.2.223
47 https://doi.org/10.1177/0148607110379813
48 https://doi.org/10.1177/0148607112452306
49 https://doi.org/10.1378/chest.101.6.1644
50 https://doi.org/10.2147/ijgm.s98280
51 https://doi.org/10.3920/bm2014.0079
52 https://doi.org/10.3945/ajcn.112.040949
53 https://doi.org/10.7326/0003-4819-113-3-227
54 schema:datePublished 2016-06
55 schema:datePublishedReg 2016-06-01
56 schema:description BACKGROUND: The health benefits of probiotics and synbiotics are well established in healthy adults, but their role in preventing postoperative sepsis remains controversial. This meta-analysis assesses the impact of probiotics and synbiotics on the incidence of postoperative sepsis in gastrointestinal (GI) surgical patients. METHODS: A comprehensive literature search of all published randomized control trials (RCTs) was conducted using PubMed, Cochrane Central Registry of Controlled Trials, and Google Scholar (1966-2015). Inclusion criteria included RCTs comparing the use of any strain or dose of a specified probiotic/synbiotic with placebo or a "no treatment" control group. The incidence of postoperative sepsis (within 1 month of surgery) and postoperative mortality were analyzed. RESULTS: Fifteen RCTs involving 1201 patients (192 receiving probiotics, 413 receiving synbiotics, and 596 receiving placebo) were analyzed. Overall, probiotic and synbiotic uses significantly reduced the risk of developing postoperative sepsis by 38 % (relative risk (RR) = 0.62, 95 % confidence interval (CI) 0.52-0.74, p < 0.001). CONCLUSIONS: The use of probiotic/synbiotic supplementation is associated with a significant reduction in the risk of developing postoperative sepsis in patients undergoing elective GI surgery. Probiotic/synbiotic supplementation is a valuable adjunct in the care of patients undergoing GI surgery. Additional studies are required to determine the optimal dose and strain of probiotic/synbiotic.
57 schema:genre research_article
58 schema:inLanguage en
59 schema:isAccessibleForFree false
60 schema:isPartOf N0817b5b044d746569ee8cb82c42739f2
61 N62a4efadd9b14646abdfdd3d45105bd2
62 sg:journal.1116755
63 schema:name Probiotics and Synbiotics Decrease Postoperative Sepsis in Elective Gastrointestinal Surgical Patients: a Meta-Analysis
64 schema:pagination 1123-1131
65 schema:productId N10a226bfd1bf47c4a60af4dfed8641c9
66 N3f87ef16037b4ee389d4d71c6688b89e
67 N8d11f7261250495ebfb7bfb0602b25f1
68 Nc852295fe4cb4a83b1157fd679acbee5
69 Nf1019e696cab4524a1537b69da394c00
70 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006218742
71 https://doi.org/10.1007/s11605-016-3142-y
72 schema:sdDatePublished 2019-04-10T19:59
73 schema:sdLicense https://scigraph.springernature.com/explorer/license/
74 schema:sdPublisher N913cf97934404bc3802b9fe3b87a2e50
75 schema:url http://link.springer.com/10.1007%2Fs11605-016-3142-y
76 sgo:license sg:explorer/license/
77 sgo:sdDataset articles
78 rdf:type schema:ScholarlyArticle
79 N0817b5b044d746569ee8cb82c42739f2 schema:issueNumber 6
80 rdf:type schema:PublicationIssue
81 N09f5c71faeaf496d8ff5e72a4d23eda7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
82 schema:name Sepsis
83 rdf:type schema:DefinedTerm
84 N10a226bfd1bf47c4a60af4dfed8641c9 schema:name readcube_id
85 schema:value 1d9f8f0207c5603d92d059bf94d32b4f10a4b32acd0ebdea1da2c5d77bfe82c7
86 rdf:type schema:PropertyValue
87 N3dd63f16411a44d3a367bb61857adb33 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
88 schema:name Probiotics
89 rdf:type schema:DefinedTerm
90 N3f87ef16037b4ee389d4d71c6688b89e schema:name nlm_unique_id
91 schema:value 9706084
92 rdf:type schema:PropertyValue
93 N62a4efadd9b14646abdfdd3d45105bd2 schema:volumeNumber 20
94 rdf:type schema:PublicationVolume
95 N712a05f78eac48f6bac20ac99b7a3ec7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
96 schema:name Digestive System Surgical Procedures
97 rdf:type schema:DefinedTerm
98 N73950121210245aeba434895c1765c4d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
99 schema:name Randomized Controlled Trials as Topic
100 rdf:type schema:DefinedTerm
101 N8d11f7261250495ebfb7bfb0602b25f1 schema:name dimensions_id
102 schema:value pub.1006218742
103 rdf:type schema:PropertyValue
104 N913cf97934404bc3802b9fe3b87a2e50 schema:name Springer Nature - SN SciGraph project
105 rdf:type schema:Organization
106 N93c15b206d9c418aadeee805db47f5a0 rdf:first sg:person.0604062134.84
107 rdf:rest rdf:nil
108 N99d2386912d34a3082435d7e71277bc8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
109 schema:name Elective Surgical Procedures
110 rdf:type schema:DefinedTerm
111 Nb661bde8e3364496bb4907ffef7e12d9 rdf:first sg:person.0716777523.41
112 rdf:rest Nee33b260ea114992ad0d4b9b4969ac07
113 Nbac59037d7e14e7ab36f4bb9501b7443 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
114 schema:name Synbiotics
115 rdf:type schema:DefinedTerm
116 Nc852295fe4cb4a83b1157fd679acbee5 schema:name pubmed_id
117 schema:value 27073082
118 rdf:type schema:PropertyValue
119 Nd1cc53debdb746c6ae5b5de05bf2d0ce schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
120 schema:name Humans
121 rdf:type schema:DefinedTerm
122 Ndf3af50034ff4723a62d161dc5477d2c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
123 schema:name Incidence
124 rdf:type schema:DefinedTerm
125 Nee33b260ea114992ad0d4b9b4969ac07 rdf:first sg:person.0705502527.07
126 rdf:rest N93c15b206d9c418aadeee805db47f5a0
127 Nf1019e696cab4524a1537b69da394c00 schema:name doi
128 schema:value 10.1007/s11605-016-3142-y
129 rdf:type schema:PropertyValue
130 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
131 schema:name Medical and Health Sciences
132 rdf:type schema:DefinedTerm
133 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
134 schema:name Clinical Sciences
135 rdf:type schema:DefinedTerm
136 sg:journal.1116755 schema:issn 1091-255X
137 1873-4626
138 schema:name Journal of Gastrointestinal Surgery
139 rdf:type schema:Periodical
140 sg:person.0604062134.84 schema:affiliation https://www.grid.ac/institutes/grid.412748.c
141 schema:familyName Chamberlain
142 schema:givenName Ronald S.
143 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0604062134.84
144 rdf:type schema:Person
145 sg:person.0705502527.07 schema:affiliation https://www.grid.ac/institutes/grid.412748.c
146 schema:familyName Lau
147 schema:givenName Christine S. M.
148 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0705502527.07
149 rdf:type schema:Person
150 sg:person.0716777523.41 schema:affiliation https://www.grid.ac/institutes/grid.416350.5
151 schema:familyName Arumugam
152 schema:givenName Sudha
153 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0716777523.41
154 rdf:type schema:Person
155 sg:pub.10.1007/10_2008_097 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007630270
156 https://doi.org/10.1007/10_2008_097
157 rdf:type schema:CreativeWork
158 sg:pub.10.1007/s00134-009-1738-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005074113
159 https://doi.org/10.1007/s00134-009-1738-3
160 rdf:type schema:CreativeWork
161 sg:pub.10.1007/s00268-015-3071-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1000591097
162 https://doi.org/10.1007/s00268-015-3071-z
163 rdf:type schema:CreativeWork
164 sg:pub.10.1007/s00423-004-0536-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050224928
165 https://doi.org/10.1007/s00423-004-0536-1
166 rdf:type schema:CreativeWork
167 sg:pub.10.1038/ejcn.2009.120 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052950129
168 https://doi.org/10.1038/ejcn.2009.120
169 rdf:type schema:CreativeWork
170 sg:pub.10.1186/s12876-015-0260-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1049183764
171 https://doi.org/10.1186/s12876-015-0260-z
172 rdf:type schema:CreativeWork
173 https://app.dimensions.ai/details/publication/pub.1074891166 schema:CreativeWork
174 https://app.dimensions.ai/details/publication/pub.1077640574 schema:CreativeWork
175 https://app.dimensions.ai/details/publication/pub.1077807759 schema:CreativeWork
176 https://doi.org/10.1001/archsurg.1990.01410150125024 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021223865
177 rdf:type schema:CreativeWork
178 https://doi.org/10.1001/jama.1995.03530040066043 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033259134
179 rdf:type schema:CreativeWork
180 https://doi.org/10.1002/bjs.1800800124 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010042783
181 rdf:type schema:CreativeWork
182 https://doi.org/10.1002/bjs.5705 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044285626
183 rdf:type schema:CreativeWork
184 https://doi.org/10.1002/bjs.9385 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012342191
185 rdf:type schema:CreativeWork
186 https://doi.org/10.1016/j.amjsurg.2009.05.025 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003626066
187 rdf:type schema:CreativeWork
188 https://doi.org/10.1016/j.amjsurg.2010.02.013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029508360
189 rdf:type schema:CreativeWork
190 https://doi.org/10.1016/j.nut.2013.03.015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003810438
191 rdf:type schema:CreativeWork
192 https://doi.org/10.1016/s0899-9007(02)00811-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039505114
193 rdf:type schema:CreativeWork
194 https://doi.org/10.1053/j.gastro.2010.10.025 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003809992
195 rdf:type schema:CreativeWork
196 https://doi.org/10.1056/nejmoa022139 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040009693
197 rdf:type schema:CreativeWork
198 https://doi.org/10.1080/01635581.2015.1004734 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010808778
199 rdf:type schema:CreativeWork
200 https://doi.org/10.1086/342912 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008641994
201 rdf:type schema:CreativeWork
202 https://doi.org/10.1093/ajcn/73.2.361s schema:sameAs https://app.dimensions.ai/details/publication/pub.1074750808
203 rdf:type schema:CreativeWork
204 https://doi.org/10.1093/ajcn/87.3.785 schema:sameAs https://app.dimensions.ai/details/publication/pub.1077617198
205 rdf:type schema:CreativeWork
206 https://doi.org/10.1093/bmb/ldh029 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045697556
207 rdf:type schema:CreativeWork
208 https://doi.org/10.1097/00003246-200107000-00002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010433290
209 rdf:type schema:CreativeWork
210 https://doi.org/10.1097/00007890-200207150-00021 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028816573
211 rdf:type schema:CreativeWork
212 https://doi.org/10.1097/00075197-200111000-00019 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017293378
213 rdf:type schema:CreativeWork
214 https://doi.org/10.1097/01.sla.0000259442.78947.19 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014575291
215 rdf:type schema:CreativeWork
216 https://doi.org/10.1097/ccm.0b013e31819285f0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023778531
217 rdf:type schema:CreativeWork
218 https://doi.org/10.1097/sla.0b013e3181dcf36e schema:sameAs https://app.dimensions.ai/details/publication/pub.1015817676
219 rdf:type schema:CreativeWork
220 https://doi.org/10.1111/j.1365-2036.2010.04492.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1040110233
221 rdf:type schema:CreativeWork
222 https://doi.org/10.1111/j.1600-6143.2004.00649.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1047916686
223 rdf:type schema:CreativeWork
224 https://doi.org/10.1136/gut.2003.024620 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045026339
225 rdf:type schema:CreativeWork
226 https://doi.org/10.1136/gut.45.2.223 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011897257
227 rdf:type schema:CreativeWork
228 https://doi.org/10.1177/0148607110379813 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020029807
229 rdf:type schema:CreativeWork
230 https://doi.org/10.1177/0148607112452306 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037593123
231 rdf:type schema:CreativeWork
232 https://doi.org/10.1378/chest.101.6.1644 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006971593
233 rdf:type schema:CreativeWork
234 https://doi.org/10.2147/ijgm.s98280 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013035227
235 rdf:type schema:CreativeWork
236 https://doi.org/10.3920/bm2014.0079 schema:sameAs https://app.dimensions.ai/details/publication/pub.1071703831
237 rdf:type schema:CreativeWork
238 https://doi.org/10.3945/ajcn.112.040949 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010945969
239 rdf:type schema:CreativeWork
240 https://doi.org/10.7326/0003-4819-113-3-227 schema:sameAs https://app.dimensions.ai/details/publication/pub.1073694869
241 rdf:type schema:CreativeWork
242 https://www.grid.ac/institutes/grid.412748.c schema:alternateName St. George's University
243 schema:name Department of Surgery, Rutgers University, New Jersey Medical School, Newark, NJ, USA
244 Department of Surgery, Saint Barnabas Medical Center, 94 Old Short Hills Road, 07039, Livingston, NJ, USA
245 Saint George’s University School of Medicine, True Blue, Grenada, West Indies
246 rdf:type schema:Organization
247 https://www.grid.ac/institutes/grid.416350.5 schema:alternateName Saint Barnabas Medical Center
248 schema:name Department of Surgery, Saint Barnabas Medical Center, 94 Old Short Hills Road, 07039, Livingston, NJ, USA
249 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...