Ontology type: schema:ScholarlyArticle
2010-08
AUTHORSJung Wook Huh, Chol Kyoon Cho, Hyeong Rok Kim, Young Jin Kim
ABSTRACTPURPOSE: This study was designed to evaluate the impact of resection for primary colorectal cancer on oncologic outcomes in patients with synchronous colorectal liver metastases. METHODS: A retrospective analysis was performed on 91 consecutive patients with synchronous colorectal liver metastases who underwent resection of the primary colorectal cancer between December 1999 and December 2007. Of the 91 patients, 54 (59.3%) also underwent complete (R0) resection for liver metastases, and 84 (92.3%) received postoperative chemotherapy. The oncologic outcomes and prognostic factors were analyzed. RESULTS: Operative mortality was 1.1%, and morbidity was 37.4%. The 3- and 5-year overall survival rates were 44.5% and 26.8%, respectively. A multivariate analysis revealed that residual disease after surgery (non-R0 resection; p = 0.003), lymph node metastasis of the primary tumor (p = 0.015), and no postoperative chemotherapy (p = 0.001) were independent prognostic factors for poor survival. Independent predictors of an inability to achieve a complete resection were the presence of three or more liver metastases and the presence of extrahepatic disease at exploration. Significant differences in survival existed among the three risk stratification groups (no-, low-, and high-risk groups; p < 0.001). CONCLUSIONS: The inability to safely render the liver and colon microscopically free of disease should cause a surgeon to reconsider synchronous colectomy and hepatectomy. A multidisciplinary approach that combines both complete resection of synchronous colorectal liver metastases and postoperative chemotherapy may achieve improved survival in patients with synchronous colorectal liver metastases. More... »
PAGES1258-1264
http://scigraph.springernature.com/pub.10.1007/s11605-010-1250-7
DOIhttp://dx.doi.org/10.1007/s11605-010-1250-7
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1014243381
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/20544397
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Oncology and Carcinogenesis",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Medical and Health Sciences",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Adenocarcinoma",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Adult",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Aged",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Aged, 80 and over",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Colectomy",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Colorectal Neoplasms",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Female",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Hepatectomy",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Humans",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Liver Neoplasms",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Magnetic Resonance Imaging",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Male",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Middle Aged",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Portography",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Positron-Emission Tomography",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Republic of Korea",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Retrospective Studies",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Survival Rate",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Tomography, X-Ray Computed",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Treatment Outcome",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"name": [
"Department of Surgery, Chonnam National University Hwasun Hospital and Medical School, 160 Ilsimri, Hwasun-eup, 519-809, Hwasun-gun, Jeonnam, South Korea"
],
"type": "Organization"
},
"familyName": "Huh",
"givenName": "Jung Wook",
"id": "sg:person.01310235260.89",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01310235260.89"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"Department of Surgery, Chonnam National University Hwasun Hospital and Medical School, 160 Ilsimri, Hwasun-eup, 519-809, Hwasun-gun, Jeonnam, South Korea"
],
"type": "Organization"
},
"familyName": "Cho",
"givenName": "Chol\u2009 Kyoon",
"id": "sg:person.01367215004.00",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01367215004.00"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"Department of Surgery, Chonnam National University Hwasun Hospital and Medical School, 160 Ilsimri, Hwasun-eup, 519-809, Hwasun-gun, Jeonnam, South Korea"
],
"type": "Organization"
},
"familyName": "Kim",
"givenName": "Hyeong Rok",
"id": "sg:person.0726026302.07",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0726026302.07"
],
"type": "Person"
},
{
"affiliation": {
"name": [
"Department of Surgery, Chonnam National University Hwasun Hospital and Medical School, 160 Ilsimri, Hwasun-eup, 519-809, Hwasun-gun, Jeonnam, South Korea"
],
"type": "Organization"
},
"familyName": "Kim",
"givenName": "Young Jin",
"id": "sg:person.01042531610.61",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01042531610.61"
],
"type": "Person"
}
],
"citation": [
{
"id": "https://doi.org/10.3393/jksc.2008.24.2.100",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1002650346"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/annonc/mdh305",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1003639157"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf02051920",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1011213075",
"https://doi.org/10.1007/bf02051920"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1007/bf02051920",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1011213075"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1007/bf02051920",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1011213075"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1200/jco.2006.06.8353",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1012458227"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1056/nejmoa032691",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1014051315"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0399-8320(04)94952-4",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1019688188"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/01.sla.0000145964.08365.01",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1022055193"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/01.sla.0000145964.08365.01",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1022055193"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf02048443",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1022090735",
"https://doi.org/10.1007/bf02048443"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1007/bf02048443",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1022090735"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1046/j.1365-2168.2001.01698.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1022363449"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/(sici)1097-0142(19960401)77:7<1254::aid-cncr5>3.0.co;2-i",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1025015403"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s1072-7515(03)00136-4",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1025191178"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s1072-7515(03)00136-4",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1025191178"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1245/s10434-006-9215-5",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1025839282",
"https://doi.org/10.1245/s10434-006-9215-5"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/sla.0b013e31815aa2c2",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1026128215"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/sla.0b013e31815aa2c2",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1026128215"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1001/archsurg.141.10.1006",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1026162949"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1245/s10434-008-0217-3",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1027039902",
"https://doi.org/10.1245/s10434-008-0217-3"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/bjs.1800820534",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1029790120"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1136/gut.52.4.568",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1032948522"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/jso.20196",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1034475300"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1046/j.1365-2168.1997.02813.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1034899848"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf00316981",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1038122014",
"https://doi.org/10.1007/bf00316981"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf00316981",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1038122014",
"https://doi.org/10.1007/bf00316981"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00000658-200206000-00002",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1041943148"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00000658-200206000-00002",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1041943148"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/bjs.5060",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1042891212"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/bjs.5060",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1042891212"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s10350-007-9025-2",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043240236",
"https://doi.org/10.1007/s10350-007-9025-2"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1007/s10350-007-9025-2",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043240236"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s10434-999-0651-x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043465120",
"https://doi.org/10.1007/s10434-999-0651-x"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1245/aso.2004.03.085",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1046932661",
"https://doi.org/10.1245/aso.2004.03.085"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1245/aso.2004.03.085",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1046932661",
"https://doi.org/10.1245/aso.2004.03.085"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf02660770",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1048099669",
"https://doi.org/10.1007/bf02660770"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1007/bf02660770",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1048099669"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1001/archsurg.135.5.530",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050280484"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1200/jco.2004.09.046",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1051354561"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/01.sla.0000128305.90650.71",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1053015953"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/01.sla.0000128305.90650.71",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1053015953"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/bjs.1800840811",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1054296418"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00000658-199909000-00004",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1060135098"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00000658-199909000-00004",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1060135098"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00000658-199909000-00004",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1060135098"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/01.sla.0000141198.92114.f6",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1060331907"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/01.sla.0000141198.92114.f6",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1060331907"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/01.sla.0000141198.92114.f6",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1060331907"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/01.sla.0000141198.92114.f6",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1060331907"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1200/jco.20.5.1248",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064202847"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1200/jco.2005.00.349",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064204185"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1200/jco.2002.20.5.1248",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1083941976"
],
"type": "CreativeWork"
}
],
"datePublished": "2010-08",
"datePublishedReg": "2010-08-01",
"description": "PURPOSE: This study was designed to evaluate the impact of resection for primary colorectal cancer on oncologic outcomes in patients with synchronous colorectal liver metastases.\nMETHODS: A retrospective analysis was performed on 91 consecutive patients with synchronous colorectal liver metastases who underwent resection of the primary colorectal cancer between December 1999 and December 2007. Of the 91 patients, 54 (59.3%) also underwent complete (R0) resection for liver metastases, and 84 (92.3%) received postoperative chemotherapy. The oncologic outcomes and prognostic factors were analyzed.\nRESULTS: Operative mortality was 1.1%, and morbidity was 37.4%. The 3- and 5-year overall survival rates were 44.5% and 26.8%, respectively. A multivariate analysis revealed that residual disease after surgery (non-R0 resection; p = 0.003), lymph node metastasis of the primary tumor (p = 0.015), and no postoperative chemotherapy (p = 0.001) were independent prognostic factors for poor survival. Independent predictors of an inability to achieve a complete resection were the presence of three or more liver metastases and the presence of extrahepatic disease at exploration. Significant differences in survival existed among the three risk stratification groups (no-, low-, and high-risk groups; p < 0.001).\nCONCLUSIONS: The inability to safely render the liver and colon microscopically free of disease should cause a surgeon to reconsider synchronous colectomy and hepatectomy. A multidisciplinary approach that combines both complete resection of synchronous colorectal liver metastases and postoperative chemotherapy may achieve improved survival in patients with synchronous colorectal liver metastases.",
"genre": "research_article",
"id": "sg:pub.10.1007/s11605-010-1250-7",
"inLanguage": [
"en"
],
"isAccessibleForFree": false,
"isPartOf": [
{
"id": "sg:journal.1116755",
"issn": [
"1091-255X",
"1873-4626"
],
"name": "Journal of Gastrointestinal Surgery",
"type": "Periodical"
},
{
"issueNumber": "8",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "14"
}
],
"name": "Impact of Resection for Primary Colorectal Cancer on Outcomes in Patients with Synchronous Colorectal Liver Metastases",
"pagination": "1258-1264",
"productId": [
{
"name": "readcube_id",
"type": "PropertyValue",
"value": [
"43db047bdbdcddca13c9f54636445dd4c9e2bb2eac36bd171b20a3c8af9dd54c"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"20544397"
]
},
{
"name": "nlm_unique_id",
"type": "PropertyValue",
"value": [
"9706084"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1007/s11605-010-1250-7"
]
},
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1014243381"
]
}
],
"sameAs": [
"https://doi.org/10.1007/s11605-010-1250-7",
"https://app.dimensions.ai/details/publication/pub.1014243381"
],
"sdDataset": "articles",
"sdDatePublished": "2019-04-11T10:31",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000349_0000000349/records_113655_00000000.jsonl",
"type": "ScholarlyArticle",
"url": "http://link.springer.com/10.1007%2Fs11605-010-1250-7"
}
]
Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s11605-010-1250-7'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s11605-010-1250-7'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s11605-010-1250-7'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s11605-010-1250-7'
This table displays all metadata directly associated to this object as RDF triples.
301 TRIPLES
21 PREDICATES
88 URIs
41 LITERALS
29 BLANK NODES