Preoperative Chemotherapy for Colorectal Liver Metastases: Impact on Hepatic Histology and Postoperative Outcome View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2007-05-10

AUTHORS

Timothy M. Pawlik, Kelly Olino, Ana Luiza Gleisner, Michael Torbenson, Richard Schulick, Michael A. Choti

ABSTRACT

Some investigators have suggested that preoperative chemotherapy for hepatic colorectal metastases may cause hepatic injury and increase perioperative morbidity and mortality. The objective of the current study was to examine whether treatment with preoperative chemotherapy was associated with hepatic injury of the nontumorous liver and whether such injury, if present, was associated with increased morbidity or mortality after hepatic resection. Two-hundred and twelve eligible patients who underwent hepatic resection for colorectal liver metastases between January 1999 and December 2005 were identified. Data on demographics, clinicopathologic characteristics, and preoperative chemotherapy details were collected and analyzed. The majority of patients received preoperative chemotherapy (n = 153; 72.2%). Chemotherapy consisted of fluoropyrimidine-based regimens: 5-FU monotherapy, 31.6%; irinotecan, 25.9%; and oxaliplatin, 14.6%. Among those patients who received chemotherapy, the type of chemotherapy regimen predicted distinct patterns of liver injury. Oxaliplatin was associated with increased likelihood of grade 3 sinusoidal dilatation (p = 0.017). Steatosis >30% was associated with irinotecan (27.3%) compared with no chemotherapy, 5-FU monotherapy, and oxaliplatin (all p < 0.05). Irinotecan also was associated with steatohepatitis, as two of the three patients with steatohepatitis had received irinotecan preoperatively. Overall, the perioperative complication rate was similar between the no-chemotherapy group (30.5%) and the chemotherapy group (35.3%) (p = 0.79). Preoperative chemotherapy was also not associated with 60-day mortality. In patients with hepatic colorectal metastases, preoperative chemotherapy is associated with hepatic injury in about 20 to 30% of patients. Furthermore, the type of hepatic injury after preoperative chemotherapy was regimen-specific. More... »

PAGES

860-868

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11605-007-0149-4

DOI

http://dx.doi.org/10.1007/s11605-007-0149-4

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1041180731

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/17492335


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged, 80 and over", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Colorectal Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Liver Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Preoperative Care", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Treatment Outcome", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Surgery, Johns Hopkins Hospital, 600 North Wolfe Street, Halsted 614, 22187-6681, Baltimore, MD, USA", 
          "id": "http://www.grid.ac/institutes/grid.411935.b", 
          "name": [
            "Department of Surgery, Johns Hopkins Hospital, 600 North Wolfe Street, Halsted 614, 22187-6681, Baltimore, MD, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pawlik", 
        "givenName": "Timothy M.", 
        "id": "sg:person.0721627074.41", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0721627074.41"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Surgery, Johns Hopkins Hospital, 600 North Wolfe Street, Halsted 614, 22187-6681, Baltimore, MD, USA", 
          "id": "http://www.grid.ac/institutes/grid.411935.b", 
          "name": [
            "Department of Surgery, Johns Hopkins Hospital, 600 North Wolfe Street, Halsted 614, 22187-6681, Baltimore, MD, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Olino", 
        "givenName": "Kelly", 
        "id": "sg:person.01127457063.99", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01127457063.99"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Surgery, Johns Hopkins Hospital, 600 North Wolfe Street, Halsted 614, 22187-6681, Baltimore, MD, USA", 
          "id": "http://www.grid.ac/institutes/grid.411935.b", 
          "name": [
            "Department of Surgery, Johns Hopkins Hospital, 600 North Wolfe Street, Halsted 614, 22187-6681, Baltimore, MD, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gleisner", 
        "givenName": "Ana Luiza", 
        "id": "sg:person.01357771454.23", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01357771454.23"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA", 
          "id": "http://www.grid.ac/institutes/grid.21107.35", 
          "name": [
            "Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Torbenson", 
        "givenName": "Michael", 
        "id": "sg:person.01322642605.09", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01322642605.09"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Surgery, Johns Hopkins Hospital, 600 North Wolfe Street, Halsted 614, 22187-6681, Baltimore, MD, USA", 
          "id": "http://www.grid.ac/institutes/grid.411935.b", 
          "name": [
            "Department of Surgery, Johns Hopkins Hospital, 600 North Wolfe Street, Halsted 614, 22187-6681, Baltimore, MD, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Schulick", 
        "givenName": "Richard", 
        "id": "sg:person.013701724657.77", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013701724657.77"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Surgery, Johns Hopkins Hospital, 600 North Wolfe Street, Halsted 614, 22187-6681, Baltimore, MD, USA", 
          "id": "http://www.grid.ac/institutes/grid.411935.b", 
          "name": [
            "Department of Surgery, Johns Hopkins Hospital, 600 North Wolfe Street, Halsted 614, 22187-6681, Baltimore, MD, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Choti", 
        "givenName": "Michael A.", 
        "id": "sg:person.0672257164.54", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0672257164.54"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1016/j.gassur.2003.08.005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002753613", 
          "https://doi.org/10.1016/j.gassur.2003.08.005"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1016/s1091-255x(98)80025-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005527163", 
          "https://doi.org/10.1016/s1091-255x(98)80025-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1016/j.gassur.2003.09.012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012172842", 
          "https://doi.org/10.1016/j.gassur.2003.09.012"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10434-001-0347-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015538540", 
          "https://doi.org/10.1007/s10434-001-0347-3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/415268a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039852182", 
          "https://doi.org/10.1038/415268a"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2007-05-10", 
    "datePublishedReg": "2007-05-10", 
    "description": "Some investigators have suggested that preoperative chemotherapy for hepatic colorectal metastases may cause hepatic injury and increase perioperative morbidity and mortality. The objective of the current study was to examine whether treatment with preoperative chemotherapy was associated with hepatic injury of the nontumorous liver and whether such injury, if present, was associated with increased morbidity or mortality after hepatic resection. Two-hundred and twelve eligible patients who underwent hepatic resection for colorectal liver metastases between January 1999 and December 2005 were identified. Data on demographics, clinicopathologic characteristics, and preoperative chemotherapy details were collected and analyzed. The majority of patients received preoperative chemotherapy (n\u2009=\u2009153; 72.2%). Chemotherapy consisted of fluoropyrimidine-based regimens: 5-FU monotherapy, 31.6%; irinotecan, 25.9%; and oxaliplatin, 14.6%. Among those patients who received chemotherapy, the type of chemotherapy regimen predicted distinct patterns of liver injury. Oxaliplatin was associated with increased likelihood of grade 3 sinusoidal dilatation (p\u2009=\u20090.017). Steatosis >30% was associated with irinotecan (27.3%) compared with no chemotherapy, 5-FU monotherapy, and oxaliplatin (all p\u2009<\u20090.05). Irinotecan also was associated with steatohepatitis, as two of the three patients with steatohepatitis had received irinotecan preoperatively. Overall, the perioperative complication rate was similar between the no-chemotherapy group (30.5%) and the chemotherapy group (35.3%) (p\u2009=\u20090.79). Preoperative chemotherapy was also not associated with 60-day mortality. In patients with hepatic colorectal metastases, preoperative chemotherapy is associated with hepatic injury in about 20 to 30% of patients. Furthermore, the type of hepatic injury after preoperative chemotherapy was regimen-specific.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/s11605-007-0149-4", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1116755", 
        "issn": [
          "1091-255X", 
          "1873-4626"
        ], 
        "name": "Journal of Gastrointestinal Surgery", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "7", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "11"
      }
    ], 
    "keywords": [
      "colorectal liver metastases", 
      "preoperative chemotherapy", 
      "hepatic colorectal metastases", 
      "hepatic injury", 
      "chemotherapy group", 
      "colorectal metastases", 
      "hepatic resection", 
      "liver metastases", 
      "fluoropyrimidine-based regimens", 
      "perioperative complication rate", 
      "majority of patients", 
      "eligible patients", 
      "chemotherapy details", 
      "perioperative morbidity", 
      "chemotherapy regimen", 
      "complication rate", 
      "postoperative outcomes", 
      "clinicopathologic characteristics", 
      "liver injury", 
      "sinusoidal dilatation", 
      "hepatic histology", 
      "nontumorous liver", 
      "such injuries", 
      "chemotherapy", 
      "patients", 
      "injury", 
      "metastasis", 
      "irinotecan", 
      "oxaliplatin", 
      "mortality", 
      "monotherapy", 
      "steatohepatitis", 
      "morbidity", 
      "resection", 
      "regimen", 
      "distinct patterns", 
      "current study", 
      "regimens", 
      "steatosis", 
      "group", 
      "dilatation", 
      "histology", 
      "liver", 
      "demographics", 
      "outcomes", 
      "treatment", 
      "investigators", 
      "majority", 
      "likelihood", 
      "study", 
      "types", 
      "rate", 
      "objective", 
      "patterns", 
      "data", 
      "impact", 
      "characteristics", 
      "detail"
    ], 
    "name": "Preoperative Chemotherapy for Colorectal Liver Metastases: Impact on Hepatic Histology and Postoperative Outcome", 
    "pagination": "860-868", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1041180731"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s11605-007-0149-4"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "17492335"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s11605-007-0149-4", 
      "https://app.dimensions.ai/details/publication/pub.1041180731"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-09-02T15:52", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220902/entities/gbq_results/article/article_445.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/s11605-007-0149-4"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s11605-007-0149-4'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s11605-007-0149-4'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s11605-007-0149-4'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s11605-007-0149-4'


 

This table displays all metadata directly associated to this object as RDF triples.

221 TRIPLES      21 PREDICATES      99 URIs      86 LITERALS      18 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s11605-007-0149-4 schema:about N1f247c81d1614d4594973cc4b926252a
2 N3ba30fd703294e51b2757de299f63cdf
3 N3c00a5cf2e62454e87d93ab57a872615
4 N44fb11e5d6214c919380865b2f653e79
5 N7ef46fff284c4ca3926b7084e1b41e67
6 N964f8b4c6e394bca8ea3b4e13b8e9cff
7 Na83ab185472548d1a3a507e5c8e009c3
8 Nbea7ea1cc83a4045a82c90ff4e8ebf08
9 Nd9fe51e2b9844850911d6088f88851f6
10 Nea0eec834b744dd79c7726920ef211d6
11 Nf7ae214be40644feaa3d8e2a8053f0ba
12 anzsrc-for:11
13 anzsrc-for:1103
14 schema:author N7fcdc743e6434a10b231fc3a13302b21
15 schema:citation sg:pub.10.1007/s10434-001-0347-3
16 sg:pub.10.1016/j.gassur.2003.08.005
17 sg:pub.10.1016/j.gassur.2003.09.012
18 sg:pub.10.1016/s1091-255x(98)80025-5
19 sg:pub.10.1038/415268a
20 schema:datePublished 2007-05-10
21 schema:datePublishedReg 2007-05-10
22 schema:description Some investigators have suggested that preoperative chemotherapy for hepatic colorectal metastases may cause hepatic injury and increase perioperative morbidity and mortality. The objective of the current study was to examine whether treatment with preoperative chemotherapy was associated with hepatic injury of the nontumorous liver and whether such injury, if present, was associated with increased morbidity or mortality after hepatic resection. Two-hundred and twelve eligible patients who underwent hepatic resection for colorectal liver metastases between January 1999 and December 2005 were identified. Data on demographics, clinicopathologic characteristics, and preoperative chemotherapy details were collected and analyzed. The majority of patients received preoperative chemotherapy (n = 153; 72.2%). Chemotherapy consisted of fluoropyrimidine-based regimens: 5-FU monotherapy, 31.6%; irinotecan, 25.9%; and oxaliplatin, 14.6%. Among those patients who received chemotherapy, the type of chemotherapy regimen predicted distinct patterns of liver injury. Oxaliplatin was associated with increased likelihood of grade 3 sinusoidal dilatation (p = 0.017). Steatosis >30% was associated with irinotecan (27.3%) compared with no chemotherapy, 5-FU monotherapy, and oxaliplatin (all p < 0.05). Irinotecan also was associated with steatohepatitis, as two of the three patients with steatohepatitis had received irinotecan preoperatively. Overall, the perioperative complication rate was similar between the no-chemotherapy group (30.5%) and the chemotherapy group (35.3%) (p = 0.79). Preoperative chemotherapy was also not associated with 60-day mortality. In patients with hepatic colorectal metastases, preoperative chemotherapy is associated with hepatic injury in about 20 to 30% of patients. Furthermore, the type of hepatic injury after preoperative chemotherapy was regimen-specific.
23 schema:genre article
24 schema:isAccessibleForFree false
25 schema:isPartOf N7c20301bfecc499587bb1bb5898d01ce
26 Na02cbc5a1dd146cc8c90bef77f399707
27 sg:journal.1116755
28 schema:keywords characteristics
29 chemotherapy
30 chemotherapy details
31 chemotherapy group
32 chemotherapy regimen
33 clinicopathologic characteristics
34 colorectal liver metastases
35 colorectal metastases
36 complication rate
37 current study
38 data
39 demographics
40 detail
41 dilatation
42 distinct patterns
43 eligible patients
44 fluoropyrimidine-based regimens
45 group
46 hepatic colorectal metastases
47 hepatic histology
48 hepatic injury
49 hepatic resection
50 histology
51 impact
52 injury
53 investigators
54 irinotecan
55 likelihood
56 liver
57 liver injury
58 liver metastases
59 majority
60 majority of patients
61 metastasis
62 monotherapy
63 morbidity
64 mortality
65 nontumorous liver
66 objective
67 outcomes
68 oxaliplatin
69 patients
70 patterns
71 perioperative complication rate
72 perioperative morbidity
73 postoperative outcomes
74 preoperative chemotherapy
75 rate
76 regimen
77 regimens
78 resection
79 sinusoidal dilatation
80 steatohepatitis
81 steatosis
82 study
83 such injuries
84 treatment
85 types
86 schema:name Preoperative Chemotherapy for Colorectal Liver Metastases: Impact on Hepatic Histology and Postoperative Outcome
87 schema:pagination 860-868
88 schema:productId N7e5f234e139b4b6db7483b5d564cc1b3
89 Naabe980c322f465eb75d79bc35e14ecb
90 Nf521e22b9e39496fafd9caf110924180
91 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041180731
92 https://doi.org/10.1007/s11605-007-0149-4
93 schema:sdDatePublished 2022-09-02T15:52
94 schema:sdLicense https://scigraph.springernature.com/explorer/license/
95 schema:sdPublisher Na204ffde635747d0a7a56f938ec5c300
96 schema:url https://doi.org/10.1007/s11605-007-0149-4
97 sgo:license sg:explorer/license/
98 sgo:sdDataset articles
99 rdf:type schema:ScholarlyArticle
100 N1f247c81d1614d4594973cc4b926252a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
101 schema:name Middle Aged
102 rdf:type schema:DefinedTerm
103 N27048151caa64fbeb3f956bdceba74c9 rdf:first sg:person.0672257164.54
104 rdf:rest rdf:nil
105 N3ba30fd703294e51b2757de299f63cdf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
106 schema:name Colorectal Neoplasms
107 rdf:type schema:DefinedTerm
108 N3c00a5cf2e62454e87d93ab57a872615 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
109 schema:name Aged, 80 and over
110 rdf:type schema:DefinedTerm
111 N44fb11e5d6214c919380865b2f653e79 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
112 schema:name Treatment Outcome
113 rdf:type schema:DefinedTerm
114 N73622bd641d0446db8d91205e4a4491b rdf:first sg:person.01357771454.23
115 rdf:rest N9c3009c1437d4cb2ac553b5b5439fe1a
116 N7c20301bfecc499587bb1bb5898d01ce schema:issueNumber 7
117 rdf:type schema:PublicationIssue
118 N7e5f234e139b4b6db7483b5d564cc1b3 schema:name dimensions_id
119 schema:value pub.1041180731
120 rdf:type schema:PropertyValue
121 N7ef46fff284c4ca3926b7084e1b41e67 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
122 schema:name Humans
123 rdf:type schema:DefinedTerm
124 N7fcdc743e6434a10b231fc3a13302b21 rdf:first sg:person.0721627074.41
125 rdf:rest Nf2e312d009c642a59b5812e830474899
126 N964f8b4c6e394bca8ea3b4e13b8e9cff schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
127 schema:name Aged
128 rdf:type schema:DefinedTerm
129 N9c3009c1437d4cb2ac553b5b5439fe1a rdf:first sg:person.01322642605.09
130 rdf:rest Nf80b428ac2e340ddb080f0f29a2bffe8
131 Na02cbc5a1dd146cc8c90bef77f399707 schema:volumeNumber 11
132 rdf:type schema:PublicationVolume
133 Na204ffde635747d0a7a56f938ec5c300 schema:name Springer Nature - SN SciGraph project
134 rdf:type schema:Organization
135 Na83ab185472548d1a3a507e5c8e009c3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
136 schema:name Male
137 rdf:type schema:DefinedTerm
138 Naabe980c322f465eb75d79bc35e14ecb schema:name doi
139 schema:value 10.1007/s11605-007-0149-4
140 rdf:type schema:PropertyValue
141 Nbea7ea1cc83a4045a82c90ff4e8ebf08 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
142 schema:name Liver Neoplasms
143 rdf:type schema:DefinedTerm
144 Nd9fe51e2b9844850911d6088f88851f6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
145 schema:name Preoperative Care
146 rdf:type schema:DefinedTerm
147 Nea0eec834b744dd79c7726920ef211d6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
148 schema:name Female
149 rdf:type schema:DefinedTerm
150 Nf2e312d009c642a59b5812e830474899 rdf:first sg:person.01127457063.99
151 rdf:rest N73622bd641d0446db8d91205e4a4491b
152 Nf521e22b9e39496fafd9caf110924180 schema:name pubmed_id
153 schema:value 17492335
154 rdf:type schema:PropertyValue
155 Nf7ae214be40644feaa3d8e2a8053f0ba schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
156 schema:name Adult
157 rdf:type schema:DefinedTerm
158 Nf80b428ac2e340ddb080f0f29a2bffe8 rdf:first sg:person.013701724657.77
159 rdf:rest N27048151caa64fbeb3f956bdceba74c9
160 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
161 schema:name Medical and Health Sciences
162 rdf:type schema:DefinedTerm
163 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
164 schema:name Clinical Sciences
165 rdf:type schema:DefinedTerm
166 sg:journal.1116755 schema:issn 1091-255X
167 1873-4626
168 schema:name Journal of Gastrointestinal Surgery
169 schema:publisher Springer Nature
170 rdf:type schema:Periodical
171 sg:person.01127457063.99 schema:affiliation grid-institutes:grid.411935.b
172 schema:familyName Olino
173 schema:givenName Kelly
174 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01127457063.99
175 rdf:type schema:Person
176 sg:person.01322642605.09 schema:affiliation grid-institutes:grid.21107.35
177 schema:familyName Torbenson
178 schema:givenName Michael
179 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01322642605.09
180 rdf:type schema:Person
181 sg:person.01357771454.23 schema:affiliation grid-institutes:grid.411935.b
182 schema:familyName Gleisner
183 schema:givenName Ana Luiza
184 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01357771454.23
185 rdf:type schema:Person
186 sg:person.013701724657.77 schema:affiliation grid-institutes:grid.411935.b
187 schema:familyName Schulick
188 schema:givenName Richard
189 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013701724657.77
190 rdf:type schema:Person
191 sg:person.0672257164.54 schema:affiliation grid-institutes:grid.411935.b
192 schema:familyName Choti
193 schema:givenName Michael A.
194 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0672257164.54
195 rdf:type schema:Person
196 sg:person.0721627074.41 schema:affiliation grid-institutes:grid.411935.b
197 schema:familyName Pawlik
198 schema:givenName Timothy M.
199 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0721627074.41
200 rdf:type schema:Person
201 sg:pub.10.1007/s10434-001-0347-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015538540
202 https://doi.org/10.1007/s10434-001-0347-3
203 rdf:type schema:CreativeWork
204 sg:pub.10.1016/j.gassur.2003.08.005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002753613
205 https://doi.org/10.1016/j.gassur.2003.08.005
206 rdf:type schema:CreativeWork
207 sg:pub.10.1016/j.gassur.2003.09.012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012172842
208 https://doi.org/10.1016/j.gassur.2003.09.012
209 rdf:type schema:CreativeWork
210 sg:pub.10.1016/s1091-255x(98)80025-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005527163
211 https://doi.org/10.1016/s1091-255x(98)80025-5
212 rdf:type schema:CreativeWork
213 sg:pub.10.1038/415268a schema:sameAs https://app.dimensions.ai/details/publication/pub.1039852182
214 https://doi.org/10.1038/415268a
215 rdf:type schema:CreativeWork
216 grid-institutes:grid.21107.35 schema:alternateName Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
217 schema:name Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
218 rdf:type schema:Organization
219 grid-institutes:grid.411935.b schema:alternateName Department of Surgery, Johns Hopkins Hospital, 600 North Wolfe Street, Halsted 614, 22187-6681, Baltimore, MD, USA
220 schema:name Department of Surgery, Johns Hopkins Hospital, 600 North Wolfe Street, Halsted 614, 22187-6681, Baltimore, MD, USA
221 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...