Characteristics of cerebral perfusion and diffusion associated with crossed cerebellar diaschisis after acute ischemic stroke View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-11-13

AUTHORS

Miao Zhang, Yanxiang Cao, Fang Wu, Cheng Zhao, Qingfeng Ma, Kuncheng Li, Jie Lu

ABSTRACT

PurposeWe aimed to investigate the possible factors associated with the occurrence of crossed cerebellar diaschisis (CCD) at the hyperacute stage of ischemic stroke using whole-brain volume perfusion CT (VPCT) combined with magnetic resonance imaging (MRI).Materials and methodsWe retrospectively analyzed 108 patients with ischemic stroke within 6 h of onset. The VPCT findings of the patients showed a unilateral perfusion deficit in the supratentorial territory. Follow-up MRI examinations were performed within 24 h after onset. The effects of the supratentorial cerebral ischemia, the location distribution, the final infarct volume and the apparent diffusion coefficient (ADC) value on the occurrence and severity of CCD were analyzed.ResultsAmong 108 patients with hyperacute cerebral ischemia, 62 (57.4%) demonstrated a contralateral cerebellar perfusion deficit on the VPCT maps. The occurrence of CCD was related to a reduction in cerebral blood volume (CBV) and prolongation of the mean transit time (MTT). Notably, the decrease in the ADC value in the infarct based on follow-up MRI was closely related to the occurrence and severity of CCD.ConclusionThe occurrence and severity of CCD are related to the degree of low supratentorial perfusion and the decrease in the ADC value of infarct focus. More... »

PAGES

126-134

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11604-019-00898-0

DOI

http://dx.doi.org/10.1007/s11604-019-00898-0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1122527192

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/31720951


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