MRI differentiation of cardiomyopathy showing left ventricular hypertrophy and heart failure: differentiation between cardiac amyloidosis, hypertrophic cardiomyopathy, and hypertensive heart ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2013-08-31

AUTHORS

Minako Takeda, Yasuo Amano, Masaki Tachi, Hitomi Tani, Kyoichi Mizuno, Shinichiro Kumita

ABSTRACT

PurposeTo evaluate the capability of MRI to differentiate cardiac amyloidosis (CA), end-stage hypertrophic cardiomyopathy (HCM), and hypertensive heart disease (HHD), which are important etiologies of left ventricular hypertrophy (LVH) and heart failure.Materials and methodsWe enrolled 26 patients presenting with both LVH and heart failure: six with CA, nine with end-stage HCM, and 11 with HHD. Cardiac function, presence of pericardial or pleural effusion, and the extent and patterns of late gadolinium enhancement (LGE) were compared among the three diseases.ResultsMyocardial LGE was observed in all six CA patients, eight end-stage HCM patients, and six HHD patients. The number of LGE segments was significantly greater in CA than in HCM or HHD (p = 0.02 for both), and all patients with CA showed a global endocardial pattern of LGE. There were significant differences among CA, HCM, and HHD in ejection fraction and end-diastolic and end-systolic volume indices (p < 0.05 for all). Pericardial effusion was observed more frequently in CA than in HCM or HHD (p = 0.04 or 0.01, respectively).ConclusionMRI is valuable for distinguishing among CA, end-stage HCM, and HHD, all of which present with LVH and heart failure. More... »

PAGES

693-700

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11604-013-0238-0

DOI

http://dx.doi.org/10.1007/s11604-013-0238-0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1041084381

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/23996116


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