Successful hyperbaric oxygen therapy for laryngeal radionecrosis after chemoradiotherapy for mesopharyngeal cancer: case report and literature review View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2012-01-19

AUTHORS

Madoka Abe, Yoshiyuki Shioyama, Kotaro Terashima, Mioko Matsuo, Iwao Hara, Satoru Uehara

ABSTRACT

Laryngeal radionecrosis is one of the most troublesome late complications of radiotherapy, because it is frequently resistant to treatment and laryngectomy is required in the worst case. Here, we report a case of laryngeal radionecrosis, successfully treated by use of hyperbaric oxygen (HBO) therapy, in which laryngectomy was avoided. A 67-year-old male received radical chemoradiotherapy (CRT) for mesopharyngeal cancer, which included radiotherapy with a total dose of 71.4 Gy/38 Fr and chemotherapy with CDDP + S-1. He developed dyspnea and throat pain 9 months after completion of CRT. Laryngoscopy revealed vocal cord impairment because of severe laryngeal edema. He was diagnosed as having laryngeal radionecrosis and initially received conservative therapy combined with antibiotics, steroids, and prostaglandins. Because his dyspnea was persistent despite this treatment, HBO therapy was administered 20 times, and resulted in complete remission of the dyspnea. HBO therapy, therefore, is regarded as an effective conservative therapeutic option for laryngeal radionecrosis. More... »

PAGES

340-344

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11604-011-0046-3

DOI

http://dx.doi.org/10.1007/s11604-011-0046-3

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1009201293

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/22258812


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