Evolving paradigm in treatment of Merkel cell carcinoma of the digit from ray resection to wide local excision and flap ... View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2015-12

AUTHORS

Alex J. Doermann, James G Jakowatz, Neil F Jones

ABSTRACT

BACKGROUND: Merkel cell carcinoma is a rare cutaneous neuroendocrine neoplasm that typically presents on the head and neck. Merkel cell carcinoma (MCC) of the digits is rare, and thus limited treatment options have been presented. METHODS: In contrast to the current treatment recommendation of ray resection of the affected digit, two patients were treated by sentinel node biopsy, wide local excision, and flap coverage of the defect. RESULTS: No local recurrences or metastases have been seen 24 months postoperatively. CONCLUSION: We suggest that the paradigm of ray amputation of a digit affected by MCC should evolve to initial treatment with a sentinel lymph node biopsy (SLNB) with subsequent local excision with wide margins and local flap coverage. More... »

PAGES

738-740

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11552-015-9756-9

DOI

http://dx.doi.org/10.1007/s11552-015-9756-9

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1000113919

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/26568733


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137 schema:name Department of Orthopedic Surgery, University of California, Irvine, 101 The City Dr S, 92868, Orange, CA, USA
138 Department of Surgical Oncology, University of California, Irvine, 101 The City Dr S, 92868, Orange, CA, USA
139 School of Medicine, University of California, Irvine, 252 Irvine Hall, 92697, Irvine, CA, USA
140 rdf:type schema:Organization
 




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