Embolisation of bone metastases from renal cancer View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2012-03-19

AUTHORS

G. Rossi, A. F. Mavrogenis, R. Casadei, G. Bianchi, C. Romagnoli, E. Rimondi, P. Ruggieri

ABSTRACT

PurposeThis study was done to evaluate embolisation for palliative and/or adjuvant treatment of bone metastases from renal cell carcinoma and discuss the clinical and imaging results.Materials and methodsWe retrospectively studied 107 patients with bone metastases from renal cell carcinoma treated from December 2002 to January 2011 with 163 embolisations using N-2-butyl cyanoacrylate (NBCA). Mean tumour diameter before embolisation was 8.8 cm and mean follow-up 4 years. Clinical and imaging effects of treatment were evaluated at follow-up examinations with a pain score scale, analgesic use, hypoattenuating areas, tumour size and ossification.ResultsA clinical response was achieved in 157 (96%) and no response in six embolisations of sacroiliac metastases. Mean duration of clinical response was 10 (range 1–12) months. Hypoattenuating areas resembling tumour necrosis were observed in all patients. Variable ossification appeared in 41 patients. Mean maximal tumour diameter after embolisation was 4.0 cm. One patient had intraprocedural tear of the left L3 artery and iliopsoas haemorrhage and was treated with occlusion of the bleeding vessel with NBCA. All patients had variable ischaemic pain that recovered completely within 2–4 days. Postembolisation syndrome was diagnosed after 15 embolisations (9.2%). Transient paraesthesias in the lower extremities were observed after 25 embolisations (25%) of pelvis and sacrum metastatic lesions.ConclusionsEmbolisation with NBCA is recommended as primary or palliative treatment of bone metastases from renal cell carcinoma. Strict adherence to the principles of transcatheter embolisation is important to avoid complications. More... »

PAGES

291-302

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11547-012-0802-4

DOI

http://dx.doi.org/10.1007/s11547-012-0802-4

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1007884362

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/22430676


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