Durability improvement of polymer chamber of pulsatile extracorporeal life support system in terms of mechanical change View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2007-11

AUTHORS

Hyuk Choi, Seung Hoon Paik, Kwang Ho Lee, Byoung Goo Min, Yong Soon Won

ABSTRACT

Twin Pulse Life Support, T-PLS has received the CE mark (2003) and Korea Food and Drug Administration (KFDA) approval (2004) for short-term application as an Extracorporeal Life Support system (ECLS). T-PLS's original intention was to apply for not only short-term but also long-term application such as Extracorporeal ventricular assist device (VAD). Hence, a long-term durability test was conducted. The 1-year reliability of the systems tested in this study did not meet the STS/ASAIO standard of 80% reliability with 60% confidence for a 1-year mission life. However, without the disposable units, which are only designed to operate for 6 h, the 1-year reliability exceeded the STS/ASAIO standard of 80% reliability with 60% confidence. In this study, by using the existing analysis methods and analyzing the root cause of the failure used by a numerical analysis. As eliminating or mitigating of the root cause of the failure, we improved the durability of blood chamber and evaluated the performance of the modified system via the hemolysis test. More... »

PAGES

1127-1135

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11517-007-0215-9

DOI

http://dx.doi.org/10.1007/s11517-007-0215-9

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1015928844

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/17721715


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