Solalyratins A and B, new anti-inflammatory metabolites from Solanum lyratum View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2012-04

AUTHORS

De-Wu Zhang, Yan Yang, Fang Yao, Qun-Ying Yu, Sheng-Jun Dai

ABSTRACT

A new coumestan (solalyratin A, 1) and a novel cyclic eight-membered α,β-unsaturated ketone (solalyratin B, 3), together with three known compounds, puerariafuran (2), coumestrol (4) and 9-hydroxy-2',2'-dimethylpyrano[5',6':2,3]-coumestan (5), were isolated from the whole plant of Solanum lyratum. Their structures were elucidated on the basis of spectroscopic analyses. In vitro, compounds 1-5 showed anti-inflammatory activities, with IC(50) values in the range 6.3-9.1 μM. More... »

PAGES

362-366

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11418-011-0581-3

DOI

http://dx.doi.org/10.1007/s11418-011-0581-3

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1038077956

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/21898133


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