Triterpene esters from Uncaria rhynchophylla drive potent IL-12-dependent Th1 polarization View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2010-10

AUTHORS

Akemi Umeyama, Yoshinori Yahisa, Minori Okada, Eriko Okayama, Ayaka Uda, Noboru Shoji, Je-Jung Lee, Masao Takei, Toshihiro Hashimoto

ABSTRACT

Dendritic cells (DC) are key antigen-presenting cells that link innate and adaptive immunity and ultimately activate antigen-specific T cells. In the current study, we demonstrated that two triterpene esters, uncarinic acid C (1) and uncarinic acid D (2), which are isolated from the hooks of Uncaria rhynchophylla, activate phenotypic and cytokine production alterations in DC. We also show that 1 and 2 modulate human DC function in a fashion that favors Th1 cell polarization. The effect of 1 (E configuration at the 2' position) was approximately 20 times more potent than that of 2 (Z configuration at 2'). These results indicated that the configuration of the 2' double bond greatly effects activity. Thus, 1 and 2 may prove useful as DC-based vaccines for cancer immunotherapy. More... »

PAGES

506-509

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11418-010-0438-1

DOI

http://dx.doi.org/10.1007/s11418-010-0438-1

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1050843558

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/20585989


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1107", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Immunology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cell Polarity", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Esters", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "HL-60 Cells", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Interleukin-12", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Plant Extracts", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Plant Structures", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Th1 Cells", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Triterpenes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Uncaria", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Tokushima Bunri University", 
          "id": "https://www.grid.ac/institutes/grid.412769.f", 
          "name": [
            "Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Tokushima, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Umeyama", 
        "givenName": "Akemi", 
        "id": "sg:person.01101371400.62", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01101371400.62"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Tokushima Bunri University", 
          "id": "https://www.grid.ac/institutes/grid.412769.f", 
          "name": [
            "Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Tokushima, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yahisa", 
        "givenName": "Yoshinori", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Tokushima Bunri University", 
          "id": "https://www.grid.ac/institutes/grid.412769.f", 
          "name": [
            "Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Tokushima, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Okada", 
        "givenName": "Minori", 
        "id": "sg:person.01155765011.02", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01155765011.02"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Tokushima Bunri University", 
          "id": "https://www.grid.ac/institutes/grid.412769.f", 
          "name": [
            "Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Tokushima, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Okayama", 
        "givenName": "Eriko", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Tokushima Bunri University", 
          "id": "https://www.grid.ac/institutes/grid.412769.f", 
          "name": [
            "Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Tokushima, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Uda", 
        "givenName": "Ayaka", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Tokushima Bunri University", 
          "id": "https://www.grid.ac/institutes/grid.412769.f", 
          "name": [
            "Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Tokushima, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shoji", 
        "givenName": "Noboru", 
        "id": "sg:person.01067216455.55", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01067216455.55"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Chonnam National University Hwasun Hospital", 
          "id": "https://www.grid.ac/institutes/grid.411602.0", 
          "name": [
            "Research Center for Cancer Immunotherapy, Chonnam National University Hwasun Hospital, Jeonnam, South Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lee", 
        "givenName": "Je-Jung", 
        "id": "sg:person.01204441075.42", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01204441075.42"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Chonnam National University Hwasun Hospital", 
          "id": "https://www.grid.ac/institutes/grid.411602.0", 
          "name": [
            "Research Center for Cancer Immunotherapy, Chonnam National University Hwasun Hospital, Jeonnam, South Korea"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Takei", 
        "givenName": "Masao", 
        "id": "sg:person.01305620125.23", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01305620125.23"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Tokushima Bunri University", 
          "id": "https://www.grid.ac/institutes/grid.412769.f", 
          "name": [
            "Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Tokushima, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hashimoto", 
        "givenName": "Toshihiro", 
        "id": "sg:person.01251245123.30", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01251245123.30"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/j.bcp.2004.04.015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002595169"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.lfs.2004.08.012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011283697"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nm1551", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016434628", 
          "https://doi.org/10.1038/nm1551"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00210-003-0854-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016809671", 
          "https://doi.org/10.1007/s00210-003-0854-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ejphar.2006.02.047", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021736294"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bbrc.2008.02.157", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029077386"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/np8000305", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056237308"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/np8000305", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056237308"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/np990478k", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056239912"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/np990478k", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056239912"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1055/s-2007-969846", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1057502613"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1055/s-2008-1081348", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1057571020"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2010-10", 
    "datePublishedReg": "2010-10-01", 
    "description": "Dendritic cells (DC) are key antigen-presenting cells that link innate and adaptive immunity and ultimately activate antigen-specific T cells. In the current study, we demonstrated that two triterpene esters, uncarinic acid C (1) and uncarinic acid D (2), which are isolated from the hooks of Uncaria rhynchophylla, activate phenotypic and cytokine production alterations in DC. We also show that 1 and 2 modulate human DC function in a fashion that favors Th1 cell polarization. The effect of 1 (E configuration at the 2' position) was approximately 20 times more potent than that of 2 (Z configuration at 2'). These results indicated that the configuration of the 2' double bond greatly effects activity. Thus, 1 and 2 may prove useful as DC-based vaccines for cancer immunotherapy.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s11418-010-0438-1", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1042407", 
        "issn": [
          "1340-3443", 
          "1861-0293"
        ], 
        "name": "Journal of Natural Medicines", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "4", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "64"
      }
    ], 
    "name": "Triterpene esters from Uncaria rhynchophylla drive potent IL-12-dependent Th1 polarization", 
    "pagination": "506-509", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "f232c7a24b53bf4d4515d45be2f55ffcb79fb874c6554eb8fc386436692435dc"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "20585989"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101518405"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s11418-010-0438-1"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1050843558"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s11418-010-0438-1", 
      "https://app.dimensions.ai/details/publication/pub.1050843558"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T10:33", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000349_0000000349/records_113658_00000002.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007%2Fs11418-010-0438-1"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s11418-010-0438-1'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s11418-010-0438-1'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s11418-010-0438-1'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s11418-010-0438-1'


 

This table displays all metadata directly associated to this object as RDF triples.

197 TRIPLES      21 PREDICATES      49 URIs      31 LITERALS      19 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s11418-010-0438-1 schema:about N19eb24fcb2b74c88839ded80fb08e951
2 N6e4e1c78e0b44f8084bb257d9038c934
3 N6edd748dca9a4593985a775bb5c8fcbf
4 N7556d908cb164fa2b5024f735ca97017
5 N809df2910f464902af83c3091f0971cd
6 N9614757726794d9fb0a99d3dbe55d81d
7 Nc0b6bfc3cc0041bab52693d753c34bbd
8 Ncb376d3d3ee54601b798d4b8d5cc5568
9 Ncf414ea0056e4b959b06ad4670369b65
10 Nd436a9dcf67a4ceea2e82e4d12fbb484
11 anzsrc-for:11
12 anzsrc-for:1107
13 schema:author N8056867486cd4ff08e8c46ab0242f0e9
14 schema:citation sg:pub.10.1007/s00210-003-0854-9
15 sg:pub.10.1038/nm1551
16 https://doi.org/10.1016/j.bbrc.2008.02.157
17 https://doi.org/10.1016/j.bcp.2004.04.015
18 https://doi.org/10.1016/j.ejphar.2006.02.047
19 https://doi.org/10.1016/j.lfs.2004.08.012
20 https://doi.org/10.1021/np8000305
21 https://doi.org/10.1021/np990478k
22 https://doi.org/10.1055/s-2007-969846
23 https://doi.org/10.1055/s-2008-1081348
24 schema:datePublished 2010-10
25 schema:datePublishedReg 2010-10-01
26 schema:description Dendritic cells (DC) are key antigen-presenting cells that link innate and adaptive immunity and ultimately activate antigen-specific T cells. In the current study, we demonstrated that two triterpene esters, uncarinic acid C (1) and uncarinic acid D (2), which are isolated from the hooks of Uncaria rhynchophylla, activate phenotypic and cytokine production alterations in DC. We also show that 1 and 2 modulate human DC function in a fashion that favors Th1 cell polarization. The effect of 1 (E configuration at the 2' position) was approximately 20 times more potent than that of 2 (Z configuration at 2'). These results indicated that the configuration of the 2' double bond greatly effects activity. Thus, 1 and 2 may prove useful as DC-based vaccines for cancer immunotherapy.
27 schema:genre research_article
28 schema:inLanguage en
29 schema:isAccessibleForFree false
30 schema:isPartOf N02e70de244fe4ccdbac30048453a186b
31 Nfc4a2ea914c741ee8e7fde4fcd8b1760
32 sg:journal.1042407
33 schema:name Triterpene esters from Uncaria rhynchophylla drive potent IL-12-dependent Th1 polarization
34 schema:pagination 506-509
35 schema:productId N287583015c6c42a899f4332f7c5d87cb
36 N4f7661d1797341219461b2258ea4fa8a
37 N8f00f354784f4d40979cc8d73a22fb95
38 N9382e7f9a9c54791b6b1adffa3d5f6fb
39 Na9e56248a2b2469d951525d095eb19f0
40 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050843558
41 https://doi.org/10.1007/s11418-010-0438-1
42 schema:sdDatePublished 2019-04-11T10:33
43 schema:sdLicense https://scigraph.springernature.com/explorer/license/
44 schema:sdPublisher N2c340de41ba94c368f1dedcac4a73bf7
45 schema:url http://link.springer.com/10.1007%2Fs11418-010-0438-1
46 sgo:license sg:explorer/license/
47 sgo:sdDataset articles
48 rdf:type schema:ScholarlyArticle
49 N02e70de244fe4ccdbac30048453a186b schema:volumeNumber 64
50 rdf:type schema:PublicationVolume
51 N1205b76da22a4565a798cd4219809cd5 rdf:first sg:person.01204441075.42
52 rdf:rest N209e4da94b0b48e29bf7e0588d7b2805
53 N19eb24fcb2b74c88839ded80fb08e951 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
54 schema:name Plant Extracts
55 rdf:type schema:DefinedTerm
56 N1ff8499564ae46f3b83c6b969cf3259a rdf:first Ndf968dbcf5764767946d63dd43e9d43f
57 rdf:rest Nd742e837843b4f2a9d25a3614f2a3fdb
58 N209e4da94b0b48e29bf7e0588d7b2805 rdf:first sg:person.01305620125.23
59 rdf:rest N22e964b7cabd4cd986f76c4f8ed166b5
60 N22e964b7cabd4cd986f76c4f8ed166b5 rdf:first sg:person.01251245123.30
61 rdf:rest rdf:nil
62 N287583015c6c42a899f4332f7c5d87cb schema:name dimensions_id
63 schema:value pub.1050843558
64 rdf:type schema:PropertyValue
65 N2c340de41ba94c368f1dedcac4a73bf7 schema:name Springer Nature - SN SciGraph project
66 rdf:type schema:Organization
67 N4f7661d1797341219461b2258ea4fa8a schema:name pubmed_id
68 schema:value 20585989
69 rdf:type schema:PropertyValue
70 N5b23885cb9fb4f5ab874d723f841ae05 schema:affiliation https://www.grid.ac/institutes/grid.412769.f
71 schema:familyName Okayama
72 schema:givenName Eriko
73 rdf:type schema:Person
74 N6e4e1c78e0b44f8084bb257d9038c934 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
75 schema:name Th1 Cells
76 rdf:type schema:DefinedTerm
77 N6edd748dca9a4593985a775bb5c8fcbf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
78 schema:name Uncaria
79 rdf:type schema:DefinedTerm
80 N73abf4e3ef79430b991e77c57ce7f85d rdf:first N8fdf56f0c7bd405584e7e2496e956982
81 rdf:rest N7d393c8f89de4f819a1bd33433c5e43a
82 N7556d908cb164fa2b5024f735ca97017 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
83 schema:name Interleukin-12
84 rdf:type schema:DefinedTerm
85 N7d393c8f89de4f819a1bd33433c5e43a rdf:first sg:person.01067216455.55
86 rdf:rest N1205b76da22a4565a798cd4219809cd5
87 N8056867486cd4ff08e8c46ab0242f0e9 rdf:first sg:person.01101371400.62
88 rdf:rest N1ff8499564ae46f3b83c6b969cf3259a
89 N809df2910f464902af83c3091f0971cd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
90 schema:name Triterpenes
91 rdf:type schema:DefinedTerm
92 N8d201a90787b46d58e04ffb68da922ba rdf:first N5b23885cb9fb4f5ab874d723f841ae05
93 rdf:rest N73abf4e3ef79430b991e77c57ce7f85d
94 N8f00f354784f4d40979cc8d73a22fb95 schema:name readcube_id
95 schema:value f232c7a24b53bf4d4515d45be2f55ffcb79fb874c6554eb8fc386436692435dc
96 rdf:type schema:PropertyValue
97 N8fdf56f0c7bd405584e7e2496e956982 schema:affiliation https://www.grid.ac/institutes/grid.412769.f
98 schema:familyName Uda
99 schema:givenName Ayaka
100 rdf:type schema:Person
101 N9382e7f9a9c54791b6b1adffa3d5f6fb schema:name doi
102 schema:value 10.1007/s11418-010-0438-1
103 rdf:type schema:PropertyValue
104 N9614757726794d9fb0a99d3dbe55d81d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
105 schema:name Humans
106 rdf:type schema:DefinedTerm
107 Na9e56248a2b2469d951525d095eb19f0 schema:name nlm_unique_id
108 schema:value 101518405
109 rdf:type schema:PropertyValue
110 Nc0b6bfc3cc0041bab52693d753c34bbd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
111 schema:name Esters
112 rdf:type schema:DefinedTerm
113 Ncb376d3d3ee54601b798d4b8d5cc5568 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
114 schema:name Plant Structures
115 rdf:type schema:DefinedTerm
116 Ncf414ea0056e4b959b06ad4670369b65 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
117 schema:name Cell Polarity
118 rdf:type schema:DefinedTerm
119 Nd436a9dcf67a4ceea2e82e4d12fbb484 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
120 schema:name HL-60 Cells
121 rdf:type schema:DefinedTerm
122 Nd742e837843b4f2a9d25a3614f2a3fdb rdf:first sg:person.01155765011.02
123 rdf:rest N8d201a90787b46d58e04ffb68da922ba
124 Ndf968dbcf5764767946d63dd43e9d43f schema:affiliation https://www.grid.ac/institutes/grid.412769.f
125 schema:familyName Yahisa
126 schema:givenName Yoshinori
127 rdf:type schema:Person
128 Nfc4a2ea914c741ee8e7fde4fcd8b1760 schema:issueNumber 4
129 rdf:type schema:PublicationIssue
130 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
131 schema:name Medical and Health Sciences
132 rdf:type schema:DefinedTerm
133 anzsrc-for:1107 schema:inDefinedTermSet anzsrc-for:
134 schema:name Immunology
135 rdf:type schema:DefinedTerm
136 sg:journal.1042407 schema:issn 1340-3443
137 1861-0293
138 schema:name Journal of Natural Medicines
139 rdf:type schema:Periodical
140 sg:person.01067216455.55 schema:affiliation https://www.grid.ac/institutes/grid.412769.f
141 schema:familyName Shoji
142 schema:givenName Noboru
143 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01067216455.55
144 rdf:type schema:Person
145 sg:person.01101371400.62 schema:affiliation https://www.grid.ac/institutes/grid.412769.f
146 schema:familyName Umeyama
147 schema:givenName Akemi
148 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01101371400.62
149 rdf:type schema:Person
150 sg:person.01155765011.02 schema:affiliation https://www.grid.ac/institutes/grid.412769.f
151 schema:familyName Okada
152 schema:givenName Minori
153 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01155765011.02
154 rdf:type schema:Person
155 sg:person.01204441075.42 schema:affiliation https://www.grid.ac/institutes/grid.411602.0
156 schema:familyName Lee
157 schema:givenName Je-Jung
158 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01204441075.42
159 rdf:type schema:Person
160 sg:person.01251245123.30 schema:affiliation https://www.grid.ac/institutes/grid.412769.f
161 schema:familyName Hashimoto
162 schema:givenName Toshihiro
163 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01251245123.30
164 rdf:type schema:Person
165 sg:person.01305620125.23 schema:affiliation https://www.grid.ac/institutes/grid.411602.0
166 schema:familyName Takei
167 schema:givenName Masao
168 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01305620125.23
169 rdf:type schema:Person
170 sg:pub.10.1007/s00210-003-0854-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016809671
171 https://doi.org/10.1007/s00210-003-0854-9
172 rdf:type schema:CreativeWork
173 sg:pub.10.1038/nm1551 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016434628
174 https://doi.org/10.1038/nm1551
175 rdf:type schema:CreativeWork
176 https://doi.org/10.1016/j.bbrc.2008.02.157 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029077386
177 rdf:type schema:CreativeWork
178 https://doi.org/10.1016/j.bcp.2004.04.015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002595169
179 rdf:type schema:CreativeWork
180 https://doi.org/10.1016/j.ejphar.2006.02.047 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021736294
181 rdf:type schema:CreativeWork
182 https://doi.org/10.1016/j.lfs.2004.08.012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011283697
183 rdf:type schema:CreativeWork
184 https://doi.org/10.1021/np8000305 schema:sameAs https://app.dimensions.ai/details/publication/pub.1056237308
185 rdf:type schema:CreativeWork
186 https://doi.org/10.1021/np990478k schema:sameAs https://app.dimensions.ai/details/publication/pub.1056239912
187 rdf:type schema:CreativeWork
188 https://doi.org/10.1055/s-2007-969846 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057502613
189 rdf:type schema:CreativeWork
190 https://doi.org/10.1055/s-2008-1081348 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057571020
191 rdf:type schema:CreativeWork
192 https://www.grid.ac/institutes/grid.411602.0 schema:alternateName Chonnam National University Hwasun Hospital
193 schema:name Research Center for Cancer Immunotherapy, Chonnam National University Hwasun Hospital, Jeonnam, South Korea
194 rdf:type schema:Organization
195 https://www.grid.ac/institutes/grid.412769.f schema:alternateName Tokushima Bunri University
196 schema:name Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Tokushima, Japan
197 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...