Ontology type: schema:ScholarlyArticle Open Access: True
2014-05
AUTHORSKadhim N. Salman, Mary A. Stuart, Jack Schmidt, T. Borges, Craig J. McClain, Farrel R. Robinson, Miao Li, Larry W. Robertson
ABSTRACTCopper (Cu) metabolism is altered in rats fed diets high in molybdenum (Mo) and low in Cu. This 10-week study was carried out to examine the effects of supplemental Mo (7.5-240 μg/g diet) on male Sprague-Dawley rats fed diets adequate in Cu (5 μg/g diet) and to determine the susceptibility of Mo-treated animals to the environmental pollutant 3,3',4,4'-tetrabromobiphenyl (TBB). After 7 weeks of dietary treatment, half of the rats in each group received a single IP injection of TBB (150 μM/kg bw), while the other half received the corn oil vehicle. Rats sacrificed at 10 weeks showed no effects of Mo on growth, feed efficiency, or selected organ or tissue weights. Dose-dependent effects on plasma Mo (0-5.1 μg/mL), plasma Cu (0.95-0.20 μg/mL), and bone Cu (3.4-10 μg/g) in control through the high dose were found. Cu sequestration in the bone of Mo-treated rats is a new finding. TBB treatment resulted in dramatic weight loss and loss of absolute organ mass. Relative organ weights were increased, except for the thymus. TBB altered the concentrations of certain amino acids. Compared to control rats, this polybrominated biphenyl congener significantly decreased plasma Cu and ceruloplasmin at higher concentrations of dietary Mo and promoted the process of plasma Cu decrease by Mo, suggesting a combined effect. More... »
PAGES6400-6409
http://scigraph.springernature.com/pub.10.1007/s11356-013-1638-5
DOIhttp://dx.doi.org/10.1007/s11356-013-1638-5
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1023419024
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/23532536
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Clinical Sciences",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Medical and Health Sciences",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Animals",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Ceruloplasmin",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Copper",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Diet",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Dietary Supplements",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Hazardous Substances",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Injections, Intraperitoneal",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Male",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Molybdenum",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Organ Size",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Polybrominated Biphenyls",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Rats",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Rats, Sprague-Dawley",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "University of Kentucky",
"id": "https://www.grid.ac/institutes/grid.266539.d",
"name": [
"Graduate Center for Toxicology, University of Kentucky, 40536, Lexington, KY, USA"
],
"type": "Organization"
},
"familyName": "Salman",
"givenName": "Kadhim N.",
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Kentucky",
"id": "https://www.grid.ac/institutes/grid.266539.d",
"name": [
"Department of Nutrition and Food Science, University of Kentucky, 40506, Lexington, KY, USA"
],
"type": "Organization"
},
"familyName": "Stuart",
"givenName": "Mary A.",
"id": "sg:person.0744441051.52",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0744441051.52"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Lexington VA Medical Center",
"id": "https://www.grid.ac/institutes/grid.413837.a",
"name": [
"Department of Medicine, Veterans Administration Medical Center, 40511, Lexington, KY, USA"
],
"type": "Organization"
},
"familyName": "Schmidt",
"givenName": "Jack",
"type": "Person"
},
{
"affiliation": {
"alternateName": "Oak Ridge National Laboratory",
"id": "https://www.grid.ac/institutes/grid.135519.a",
"name": [
"Graduate Center for Toxicology, University of Kentucky, 40536, Lexington, KY, USA",
"Oak Ridge National Laboratory, 37830, Oak Ridge, TN, USA"
],
"type": "Organization"
},
"familyName": "Borges",
"givenName": "T.",
"id": "sg:person.01371771661.28",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01371771661.28"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Louisville",
"id": "https://www.grid.ac/institutes/grid.266623.5",
"name": [
"Departments of Medicine, and Pharmacology and Toxicology, University of Louisville, 40292, Louisville, KY, USA",
"Department of Medicine, Robley Rex Louisville VAMC, 40206, Louisville, KY, USA"
],
"type": "Organization"
},
"familyName": "McClain",
"givenName": "Craig J.",
"id": "sg:person.0723633340.40",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0723633340.40"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Purdue University",
"id": "https://www.grid.ac/institutes/grid.169077.e",
"name": [
"Animal Disease Diagnostic Laboratory, Purdue University, 47907, West Lafayette, IN, USA"
],
"type": "Organization"
},
"familyName": "Robinson",
"givenName": "Farrel R.",
"id": "sg:person.01302532570.00",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01302532570.00"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Iowa",
"id": "https://www.grid.ac/institutes/grid.214572.7",
"name": [
"Interdisciplinary Graduate Program in Human Toxicology, University of Iowa, 52242, Iowa City, IA, USA"
],
"type": "Organization"
},
"familyName": "Li",
"givenName": "Miao",
"id": "sg:person.01312635163.31",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01312635163.31"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Iowa",
"id": "https://www.grid.ac/institutes/grid.214572.7",
"name": [
"Graduate Center for Toxicology, University of Kentucky, 40536, Lexington, KY, USA",
"Interdisciplinary Graduate Program in Human Toxicology, University of Iowa, 52242, Iowa City, IA, USA",
"Department of Occupational and Environmental Health, College of Public Health, The University of Iowa, 100 Oakdale Campus #219 IREH, 52242-5000, Iowa City, IA, USA"
],
"type": "Organization"
},
"familyName": "Robertson",
"givenName": "Larry W.",
"id": "sg:person.0772037545.01",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0772037545.01"
],
"type": "Person"
}
],
"citation": [
{
"id": "https://doi.org/10.1016/0045-6535(93)90216-r",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1001654630"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0045-6535(93)90216-r",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1001654630"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0048-9697(91)90022-7",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1006263238"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0048-9697(91)90022-7",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1006263238"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.scitotenv.2008.03.010",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1006656233"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1080/15287398309530322",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1007154398"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.pharma.2010.10.002",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1008713304"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.bbamcr.2008.05.002",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1009465606"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/eji.1830180510",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1011670801"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0300-483x(84)90101-x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1013547599"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0300-483x(84)90101-x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1013547599"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.scitotenv.2009.05.031",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1013886539"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1084/jem.162.3.930",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1021641017"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0733-5210(87)80043-7",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1021793061"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1079/pns19740053",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1021863736"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1079/pns19740053",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1021863736"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1079/bjn19740043",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1026495114"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1079/bjn19740043",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1026495114"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.envint.2009.11.002",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1027329457"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0045-6535(86)90059-7",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1029356335"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0045-6535(86)90059-7",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1029356335"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature08302",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1029384874",
"https://doi.org/10.1038/nature08302"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature08302",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1029384874",
"https://doi.org/10.1038/nature08302"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/mco.0b013e328314b678",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1033401877"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/mco.0b013e328314b678",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1033401877"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0378-4274(90)90039-o",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1034210749"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0378-4274(90)90039-o",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1034210749"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.chemosphere.2007.11.065",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1034420682"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0378-4347(91)80354-f",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1039360534"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1079/bjn19800095",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1041100225"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1079/bjn19800095",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1041100225"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1079/bjn19830013",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1041823485"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf01970657",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1042765580",
"https://doi.org/10.1007/bf01970657"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/toxsci/kfr215",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1049175466"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.microc.2004.10.001",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050115248"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0024-3205(01)01212-7",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1053644570"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1021/jf00083a016",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1055895716"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.2527/1996.741211x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1070879389"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.2527/1997.75113057x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1070879764"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/jn/51.2.295",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1075455076"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/jn/54.2.215",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1075549385"
],
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1077966130",
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/jn/118.3.375",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1079645741"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1152/ajpendo.1979.236.6.e763",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1080342589"
],
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1081104306",
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/jn/95.2.191",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1081251619"
],
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1082304762",
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.2527/1994.72102722x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1082549858"
],
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1082785765",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1082880694",
"type": "CreativeWork"
}
],
"datePublished": "2014-05",
"datePublishedReg": "2014-05-01",
"description": "Copper (Cu) metabolism is altered in rats fed diets high in molybdenum (Mo) and low in Cu. This 10-week study was carried out to examine the effects of supplemental Mo (7.5-240 \u03bcg/g diet) on male Sprague-Dawley rats fed diets adequate in Cu (5 \u03bcg/g diet) and to determine the susceptibility of Mo-treated animals to the environmental pollutant 3,3',4,4'-tetrabromobiphenyl (TBB). After 7 weeks of dietary treatment, half of the rats in each group received a single IP injection of TBB (150 \u03bcM/kg bw), while the other half received the corn oil vehicle. Rats sacrificed at 10 weeks showed no effects of Mo on growth, feed efficiency, or selected organ or tissue weights. Dose-dependent effects on plasma Mo (0-5.1 \u03bcg/mL), plasma Cu (0.95-0.20 \u03bcg/mL), and bone Cu (3.4-10 \u03bcg/g) in control through the high dose were found. Cu sequestration in the bone of Mo-treated rats is a new finding. TBB treatment resulted in dramatic weight loss and loss of absolute organ mass. Relative organ weights were increased, except for the thymus. TBB altered the concentrations of certain amino acids. Compared to control rats, this polybrominated biphenyl congener significantly decreased plasma Cu and ceruloplasmin at higher concentrations of dietary Mo and promoted the process of plasma Cu decrease by Mo, suggesting a combined effect.",
"genre": "research_article",
"id": "sg:pub.10.1007/s11356-013-1638-5",
"inLanguage": [
"en"
],
"isAccessibleForFree": true,
"isFundedItemOf": [
{
"id": "sg:grant.2439971",
"type": "MonetaryGrant"
},
{
"id": "sg:grant.2439094",
"type": "MonetaryGrant"
}
],
"isPartOf": [
{
"id": "sg:journal.1113424",
"issn": [
"0944-1344",
"1614-7499"
],
"name": "Environmental Science and Pollution Research",
"type": "Periodical"
},
{
"issueNumber": "10",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "21"
}
],
"name": "The effects of 3,3\u2032,4,4\u2032-tetrabromobiphenyl on rats fed diets containing a constant level of copper and varying levels of molybdenum",
"pagination": "6400-6409",
"productId": [
{
"name": "readcube_id",
"type": "PropertyValue",
"value": [
"6f93458196e97db257edf131ee640e6bf5fef1e0c8bd6417c5dd15f6257ccecb"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"23532536"
]
},
{
"name": "nlm_unique_id",
"type": "PropertyValue",
"value": [
"9441769"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1007/s11356-013-1638-5"
]
},
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1023419024"
]
}
],
"sameAs": [
"https://doi.org/10.1007/s11356-013-1638-5",
"https://app.dimensions.ai/details/publication/pub.1023419024"
],
"sdDataset": "articles",
"sdDatePublished": "2019-04-10T17:34",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8672_00000521.jsonl",
"type": "ScholarlyArticle",
"url": "http://link.springer.com/10.1007%2Fs11356-013-1638-5"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s11356-013-1638-5'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s11356-013-1638-5'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s11356-013-1638-5'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s11356-013-1638-5'
This table displays all metadata directly associated to this object as RDF triples.
309 TRIPLES
21 PREDICATES
82 URIs
34 LITERALS
22 BLANK NODES