Antibiotic susceptibility of Staphylococcus aureus isolated from subclinical bovine mastitis cases and in vitro efficacy of bacteriophage View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2018-07-24

AUTHORS

Diego F. Varela-Ortiz, José E. Barboza-Corona, Joaquín González-Marrero, Ma. Fabiola León-Galván, Mauricio Valencia-Posadas, Alma A. Lechuga-Arana, Cynthia G. Sánchez-Felipe, Fernanda Ledezma-García, Abner J. Gutiérrez-Chávez

ABSTRACT

Staphylococcus aureus is an opportunistic pathogen that may cause severe infections in livestock, and represents the major cause of mastitis in dairy cows. Currently, instead of using antibiotics, new strategies are sought to reduce this clinical health problem. The aim of this study was to determine the efficacy of phage therapy to kill S. aureus strains obtained from farms located at the State of Guanajuato, México. Thirty-six S. aureus strains from cow milk with subclinical mastitis were isolated and identified, and the susceptibility to antibiotics and four phages also isolated in this work was tested. It was found that more of 90% of S. aureus isolates were not susceptible to six or more antibiotics, and 100% were resistant to penicillin, dicloxacillin, cefotaxime, ampicillin and cephalothin, and 81 and 77%, to tetracycline and cefuroxime, respectively. Fortunately, 100% of S. aureus isolates were susceptible to phages used in this work, which was detected as clear zones using specific phage. It was shown for the first time, that phages used in this study are active against pathogenic S. aureus and might be incorporated into the therapy as an important tool for the control of staphylococcal bovine mastitis, specially to antibiotic-resistant S. aureus strains isolated in farm located at the state of Guanajuato, México; and its use might be extended to other regions inside or outside the country. More... »

PAGES

243-250

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11259-018-9730-4

DOI

http://dx.doi.org/10.1007/s11259-018-9730-4

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1105806582

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30043292


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/07", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Agricultural and Veterinary Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0707", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Veterinary Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Anti-Bacterial Agents", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Bacteriophages", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cattle", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Drug Resistance, Bacterial", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "In Vitro Techniques", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mastitis, Bovine", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mexico", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Staphylococcal Infections", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Staphylococcus aureus", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Estudiante de la Unidad Profesional Interdisciplinaria de Ingenier\u00eda Campus Guanajuato, Ingenier\u00eda Farmac\u00e9utica, IPN, 36275, Silao, Guanajuato, Mexico", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Estudiante de la Unidad Profesional Interdisciplinaria de Ingenier\u00eda Campus Guanajuato, Ingenier\u00eda Farmac\u00e9utica, IPN, 36275, Silao, Guanajuato, Mexico"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Varela-Ortiz", 
        "givenName": "Diego F.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Campus Irapuato-Salamanca, Divisi\u00f3n de Ciencias de la Vida, Departamento de Alimentos, Universidad de Guanajuato, 36500, Irapuato, Guanajuato, Mexico", 
          "id": "http://www.grid.ac/institutes/grid.412891.7", 
          "name": [
            "Campus Irapuato-Salamanca, Divisi\u00f3n de Ciencias de la Vida, Posgrado en Biociencias, Universidad de Guanajuato, 36500, Irapuato, Guanajuato, Mexico", 
            "Campus Irapuato-Salamanca, Divisi\u00f3n de Ciencias de la Vida, Departamento de Alimentos, Universidad de Guanajuato, 36500, Irapuato, Guanajuato, Mexico"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Barboza-Corona", 
        "givenName": "Jos\u00e9 E.", 
        "id": "sg:person.0745304467.10", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0745304467.10"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Instituto Polit\u00e9cnico Nacional, UPIIG, 36275, Silao, Guanajuato, Mexico", 
          "id": "http://www.grid.ac/institutes/grid.418275.d", 
          "name": [
            "Instituto Polit\u00e9cnico Nacional, UPIIG, 36275, Silao, Guanajuato, Mexico"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gonz\u00e1lez-Marrero", 
        "givenName": "Joaqu\u00edn", 
        "id": "sg:person.0727577161.69", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0727577161.69"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Campus Irapuato-Salamanca, Divisi\u00f3n de Ciencias de la Vida, Departamento de Alimentos, Universidad de Guanajuato, 36500, Irapuato, Guanajuato, Mexico", 
          "id": "http://www.grid.ac/institutes/grid.412891.7", 
          "name": [
            "Campus Irapuato-Salamanca, Divisi\u00f3n de Ciencias de la Vida, Posgrado en Biociencias, Universidad de Guanajuato, 36500, Irapuato, Guanajuato, Mexico", 
            "Campus Irapuato-Salamanca, Divisi\u00f3n de Ciencias de la Vida, Departamento de Alimentos, Universidad de Guanajuato, 36500, Irapuato, Guanajuato, Mexico"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Le\u00f3n-Galv\u00e1n", 
        "givenName": "Ma. Fabiola", 
        "id": "sg:person.01357513333.40", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01357513333.40"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Campus Irapuato-Salamanca, Divisi\u00f3n de Ciencias de la Vida, Departamento de Veterinaria y Zootecnia, Universidad de Guanajuato, 36500, Irapuato, Guanajuato, Mexico", 
          "id": "http://www.grid.ac/institutes/grid.412891.7", 
          "name": [
            "Campus Irapuato-Salamanca, Divisi\u00f3n de Ciencias de la Vida, Posgrado en Biociencias, Universidad de Guanajuato, 36500, Irapuato, Guanajuato, Mexico", 
            "Campus Irapuato-Salamanca, Divisi\u00f3n de Ciencias de la Vida, Departamento de Veterinaria y Zootecnia, Universidad de Guanajuato, 36500, Irapuato, Guanajuato, Mexico"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Valencia-Posadas", 
        "givenName": "Mauricio", 
        "id": "sg:person.01233266671.23", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01233266671.23"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Estudiante de la Universidad de Guanajuato, Campus Irapuato-Salamanca, Divisi\u00f3n de Ciencias de la Vida, Posgrado en Biociencias, 36500, Irapuato, Guanajuato, Mexico", 
          "id": "http://www.grid.ac/institutes/grid.412891.7", 
          "name": [
            "Estudiante de la Universidad de Guanajuato, Campus Irapuato-Salamanca, Divisi\u00f3n de Ciencias de la Vida, Posgrado en Biociencias, 36500, Irapuato, Guanajuato, Mexico"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lechuga-Arana", 
        "givenName": "Alma A.", 
        "id": "sg:person.01350164416.17", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01350164416.17"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Consultor\u00eda en Biotecnolog\u00eda, Bioingenier\u00eda y Servicios Asociados, S. A. de C. V. (COBBYSA), 37548, San Miguel Le\u00f3n, Guanajuato, Mexico", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Consultor\u00eda en Biotecnolog\u00eda, Bioingenier\u00eda y Servicios Asociados, S. A. de C. V. (COBBYSA), 37548, San Miguel Le\u00f3n, Guanajuato, Mexico"
          ], 
          "type": "Organization"
        }, 
        "familyName": "S\u00e1nchez-Felipe", 
        "givenName": "Cynthia G.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Consultor\u00eda en Biotecnolog\u00eda, Bioingenier\u00eda y Servicios Asociados, S. A. de C. V. (COBBYSA), 37548, San Miguel Le\u00f3n, Guanajuato, Mexico", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Consultor\u00eda en Biotecnolog\u00eda, Bioingenier\u00eda y Servicios Asociados, S. A. de C. V. (COBBYSA), 37548, San Miguel Le\u00f3n, Guanajuato, Mexico"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ledezma-Garc\u00eda", 
        "givenName": "Fernanda", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Campus Irapuato-Salamanca, Divisi\u00f3n de Ciencias de la Vida, Departamento de Veterinaria y Zootecnia, Universidad de Guanajuato, 36500, Irapuato, Guanajuato, Mexico", 
          "id": "http://www.grid.ac/institutes/grid.412891.7", 
          "name": [
            "Campus Irapuato-Salamanca, Divisi\u00f3n de Ciencias de la Vida, Posgrado en Biociencias, Universidad de Guanajuato, 36500, Irapuato, Guanajuato, Mexico", 
            "Campus Irapuato-Salamanca, Divisi\u00f3n de Ciencias de la Vida, Departamento de Veterinaria y Zootecnia, Universidad de Guanajuato, 36500, Irapuato, Guanajuato, Mexico"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Guti\u00e9rrez-Ch\u00e1vez", 
        "givenName": "Abner J.", 
        "id": "sg:person.01055366011.56", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01055366011.56"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/s00705-011-1160-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010333258", 
          "https://doi.org/10.1007/s00705-011-1160-3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-1-60327-164-6_1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004942703", 
          "https://doi.org/10.1007/978-1-60327-164-6_1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1743-422x-9-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041849667", 
          "https://doi.org/10.1186/1743-422x-9-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/srep25063", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025404478", 
          "https://doi.org/10.1038/srep25063"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s13594-014-0195-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003592157", 
          "https://doi.org/10.1007/s13594-014-0195-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00284-015-0958-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043812822", 
          "https://doi.org/10.1007/s00284-015-0958-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02931564", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044703101", 
          "https://doi.org/10.1007/bf02931564"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2018-07-24", 
    "datePublishedReg": "2018-07-24", 
    "description": "Staphylococcus aureus is an opportunistic pathogen that may cause severe infections in livestock, and represents the major cause of mastitis in dairy cows. Currently, instead of using antibiotics, new strategies are sought to reduce this clinical health problem. The aim of this study was to determine the efficacy of phage therapy to kill S. aureus strains obtained from farms located at the State of Guanajuato, M\u00e9xico. Thirty-six S. aureus strains from cow milk with subclinical mastitis were isolated and identified, and the susceptibility to antibiotics and four phages also isolated in this work was tested. It was found that more of 90% of S. aureus isolates were not susceptible to six or more antibiotics, and 100% were resistant to penicillin, dicloxacillin, cefotaxime, ampicillin and cephalothin, and 81 and 77%, to tetracycline and cefuroxime, respectively. Fortunately, 100% of S. aureus isolates were susceptible to phages used in this work, which was detected as clear zones using specific phage. It was shown for the first time, that phages used in this study are active against pathogenic S. aureus and might be incorporated into the therapy as an important tool for the control of staphylococcal bovine mastitis, specially to antibiotic-resistant S. aureus strains isolated in farm located at the state of Guanajuato, M\u00e9xico; and its use might be extended to other regions inside or outside the country.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/s11259-018-9730-4", 
    "inLanguage": "en", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1091998", 
        "issn": [
          "0165-7380", 
          "1573-7446"
        ], 
        "name": "Veterinary Research Communications", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "3", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "42"
      }
    ], 
    "keywords": [
      "aureus isolates", 
      "clinical health problems", 
      "subclinical bovine mastitis cases", 
      "staphylococcal bovine mastitis", 
      "Staphylococcus aureus", 
      "efficacy of bacteriophage", 
      "severe infections", 
      "more antibiotics", 
      "antibiotic susceptibility", 
      "health problems", 
      "major cause", 
      "bovine mastitis cases", 
      "antibiotics", 
      "phage therapy", 
      "therapy", 
      "opportunistic pathogen", 
      "bovine mastitis", 
      "mastitis cases", 
      "aureus", 
      "cow's milk", 
      "efficacy", 
      "mastitis", 
      "subclinical mastitis", 
      "dairy cows", 
      "clear zone", 
      "susceptibility", 
      "cefuroxime", 
      "infection", 
      "isolates", 
      "cefotaxime", 
      "cephalothin", 
      "penicillin", 
      "ampicillin", 
      "new strategy", 
      "specific phages", 
      "study", 
      "dicloxacillin", 
      "cause", 
      "tetracycline", 
      "aim", 
      "pathogens", 
      "milk", 
      "state of Guanajuato", 
      "important tool", 
      "cows", 
      "control", 
      "phages", 
      "cases", 
      "first time", 
      "use", 
      "strategies", 
      "time", 
      "countries", 
      "bacteriophages", 
      "farms", 
      "state", 
      "region", 
      "tool", 
      "Guanajuato", 
      "livestock", 
      "M\u00e9xico", 
      "problem", 
      "work", 
      "zone"
    ], 
    "name": "Antibiotic susceptibility of Staphylococcus aureus isolated from subclinical bovine mastitis cases and in vitro efficacy of bacteriophage", 
    "pagination": "243-250", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1105806582"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s11259-018-9730-4"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30043292"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s11259-018-9730-4", 
      "https://app.dimensions.ai/details/publication/pub.1105806582"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-01-01T18:46", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220101/entities/gbq_results/article/article_786.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/s11259-018-9730-4"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s11259-018-9730-4'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s11259-018-9730-4'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s11259-018-9730-4'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s11259-018-9730-4'


 

This table displays all metadata directly associated to this object as RDF triples.

264 TRIPLES      22 PREDICATES      108 URIs      93 LITERALS      18 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s11259-018-9730-4 schema:about N032c5571a5794675a84bb0de8f07b35a
2 N0d583866c2a44709b70a602ea0689cbf
3 N3b7970b0c4f644bd969656df06efea89
4 N5aced7572d91470dbf5c6576118216e0
5 N5dc5459bb9ac4d699e44fee9cc323ab7
6 N797bb8223ce643998291d7617525a094
7 N92d40e3bdaf34a08948d3c0ebec77cd0
8 Nbc8b9c0f87054b61a597451001458171
9 Nc068724b9a7b4509a82973046072fe54
10 Ne4d2913e18084b7a8b55d4c0b253ed91
11 Neb3c875ac60a4345a00d7e8965be7652
12 anzsrc-for:07
13 anzsrc-for:0707
14 schema:author N0f9b46b2657c4558aa1e0ec7f17ee345
15 schema:citation sg:pub.10.1007/978-1-60327-164-6_1
16 sg:pub.10.1007/bf02931564
17 sg:pub.10.1007/s00284-015-0958-8
18 sg:pub.10.1007/s00705-011-1160-3
19 sg:pub.10.1007/s13594-014-0195-0
20 sg:pub.10.1038/srep25063
21 sg:pub.10.1186/1743-422x-9-9
22 schema:datePublished 2018-07-24
23 schema:datePublishedReg 2018-07-24
24 schema:description Staphylococcus aureus is an opportunistic pathogen that may cause severe infections in livestock, and represents the major cause of mastitis in dairy cows. Currently, instead of using antibiotics, new strategies are sought to reduce this clinical health problem. The aim of this study was to determine the efficacy of phage therapy to kill S. aureus strains obtained from farms located at the State of Guanajuato, México. Thirty-six S. aureus strains from cow milk with subclinical mastitis were isolated and identified, and the susceptibility to antibiotics and four phages also isolated in this work was tested. It was found that more of 90% of S. aureus isolates were not susceptible to six or more antibiotics, and 100% were resistant to penicillin, dicloxacillin, cefotaxime, ampicillin and cephalothin, and 81 and 77%, to tetracycline and cefuroxime, respectively. Fortunately, 100% of S. aureus isolates were susceptible to phages used in this work, which was detected as clear zones using specific phage. It was shown for the first time, that phages used in this study are active against pathogenic S. aureus and might be incorporated into the therapy as an important tool for the control of staphylococcal bovine mastitis, specially to antibiotic-resistant S. aureus strains isolated in farm located at the state of Guanajuato, México; and its use might be extended to other regions inside or outside the country.
25 schema:genre article
26 schema:inLanguage en
27 schema:isAccessibleForFree false
28 schema:isPartOf N574accced619444685e598a6aa680c8b
29 Ndcfd89ee31a24a84ac82f13ff8b8d8c1
30 sg:journal.1091998
31 schema:keywords Guanajuato
32 México
33 Staphylococcus aureus
34 aim
35 ampicillin
36 antibiotic susceptibility
37 antibiotics
38 aureus
39 aureus isolates
40 bacteriophages
41 bovine mastitis
42 bovine mastitis cases
43 cases
44 cause
45 cefotaxime
46 cefuroxime
47 cephalothin
48 clear zone
49 clinical health problems
50 control
51 countries
52 cow's milk
53 cows
54 dairy cows
55 dicloxacillin
56 efficacy
57 efficacy of bacteriophage
58 farms
59 first time
60 health problems
61 important tool
62 infection
63 isolates
64 livestock
65 major cause
66 mastitis
67 mastitis cases
68 milk
69 more antibiotics
70 new strategy
71 opportunistic pathogen
72 pathogens
73 penicillin
74 phage therapy
75 phages
76 problem
77 region
78 severe infections
79 specific phages
80 staphylococcal bovine mastitis
81 state
82 state of Guanajuato
83 strategies
84 study
85 subclinical bovine mastitis cases
86 subclinical mastitis
87 susceptibility
88 tetracycline
89 therapy
90 time
91 tool
92 use
93 work
94 zone
95 schema:name Antibiotic susceptibility of Staphylococcus aureus isolated from subclinical bovine mastitis cases and in vitro efficacy of bacteriophage
96 schema:pagination 243-250
97 schema:productId N55a4b611455f4b90bdabf24e7d594103
98 Nd9a862ea96524246b31ae15258c81178
99 Nf407080a8ef147ae960109a3ceaf4565
100 schema:sameAs https://app.dimensions.ai/details/publication/pub.1105806582
101 https://doi.org/10.1007/s11259-018-9730-4
102 schema:sdDatePublished 2022-01-01T18:46
103 schema:sdLicense https://scigraph.springernature.com/explorer/license/
104 schema:sdPublisher N19303fbd57a74b6dbc27ca40a0c9a6b7
105 schema:url https://doi.org/10.1007/s11259-018-9730-4
106 sgo:license sg:explorer/license/
107 sgo:sdDataset articles
108 rdf:type schema:ScholarlyArticle
109 N0281ff4afa0443e8a152e166946f2956 rdf:first N84f4113d2a584be4a15e12bf77593f18
110 rdf:rest N8d9d8639f3b546cb97d81380e57f9daf
111 N032c5571a5794675a84bb0de8f07b35a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
112 schema:name Mexico
113 rdf:type schema:DefinedTerm
114 N0d583866c2a44709b70a602ea0689cbf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
115 schema:name Bacteriophages
116 rdf:type schema:DefinedTerm
117 N0f9b46b2657c4558aa1e0ec7f17ee345 rdf:first N49a3874823c146f9ac5c1ec52b9cf8e2
118 rdf:rest Ncd867c2bff8049e5bcd8fc15167343d5
119 N19303fbd57a74b6dbc27ca40a0c9a6b7 schema:name Springer Nature - SN SciGraph project
120 rdf:type schema:Organization
121 N35902f68a63c4b958cb94c44e7c7143f rdf:first sg:person.01233266671.23
122 rdf:rest N9c23730ac2dd4773bad3e4fbbe8143c5
123 N3b7970b0c4f644bd969656df06efea89 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
124 schema:name Animals
125 rdf:type schema:DefinedTerm
126 N49a3874823c146f9ac5c1ec52b9cf8e2 schema:affiliation grid-institutes:None
127 schema:familyName Varela-Ortiz
128 schema:givenName Diego F.
129 rdf:type schema:Person
130 N4f5cd95e1e3740a1a3356cc588c1e658 rdf:first sg:person.0727577161.69
131 rdf:rest Nef321a2731d14b5da3ff22810ba410ab
132 N55a4b611455f4b90bdabf24e7d594103 schema:name dimensions_id
133 schema:value pub.1105806582
134 rdf:type schema:PropertyValue
135 N574accced619444685e598a6aa680c8b schema:issueNumber 3
136 rdf:type schema:PublicationIssue
137 N5aced7572d91470dbf5c6576118216e0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
138 schema:name Staphylococcus aureus
139 rdf:type schema:DefinedTerm
140 N5dc5459bb9ac4d699e44fee9cc323ab7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
141 schema:name Mastitis, Bovine
142 rdf:type schema:DefinedTerm
143 N797bb8223ce643998291d7617525a094 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
144 schema:name Cattle
145 rdf:type schema:DefinedTerm
146 N84f4113d2a584be4a15e12bf77593f18 schema:affiliation grid-institutes:None
147 schema:familyName Ledezma-García
148 schema:givenName Fernanda
149 rdf:type schema:Person
150 N8d9d8639f3b546cb97d81380e57f9daf rdf:first sg:person.01055366011.56
151 rdf:rest rdf:nil
152 N92d40e3bdaf34a08948d3c0ebec77cd0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
153 schema:name Female
154 rdf:type schema:DefinedTerm
155 N9c23730ac2dd4773bad3e4fbbe8143c5 rdf:first sg:person.01350164416.17
156 rdf:rest Nb79957b57deb4d65b1b3eba094b5cff6
157 Nb4713bddf22341628ced132f443d8925 schema:affiliation grid-institutes:None
158 schema:familyName Sánchez-Felipe
159 schema:givenName Cynthia G.
160 rdf:type schema:Person
161 Nb79957b57deb4d65b1b3eba094b5cff6 rdf:first Nb4713bddf22341628ced132f443d8925
162 rdf:rest N0281ff4afa0443e8a152e166946f2956
163 Nbc8b9c0f87054b61a597451001458171 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
164 schema:name Anti-Bacterial Agents
165 rdf:type schema:DefinedTerm
166 Nc068724b9a7b4509a82973046072fe54 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
167 schema:name In Vitro Techniques
168 rdf:type schema:DefinedTerm
169 Ncd867c2bff8049e5bcd8fc15167343d5 rdf:first sg:person.0745304467.10
170 rdf:rest N4f5cd95e1e3740a1a3356cc588c1e658
171 Nd9a862ea96524246b31ae15258c81178 schema:name doi
172 schema:value 10.1007/s11259-018-9730-4
173 rdf:type schema:PropertyValue
174 Ndcfd89ee31a24a84ac82f13ff8b8d8c1 schema:volumeNumber 42
175 rdf:type schema:PublicationVolume
176 Ne4d2913e18084b7a8b55d4c0b253ed91 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
177 schema:name Drug Resistance, Bacterial
178 rdf:type schema:DefinedTerm
179 Neb3c875ac60a4345a00d7e8965be7652 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
180 schema:name Staphylococcal Infections
181 rdf:type schema:DefinedTerm
182 Nef321a2731d14b5da3ff22810ba410ab rdf:first sg:person.01357513333.40
183 rdf:rest N35902f68a63c4b958cb94c44e7c7143f
184 Nf407080a8ef147ae960109a3ceaf4565 schema:name pubmed_id
185 schema:value 30043292
186 rdf:type schema:PropertyValue
187 anzsrc-for:07 schema:inDefinedTermSet anzsrc-for:
188 schema:name Agricultural and Veterinary Sciences
189 rdf:type schema:DefinedTerm
190 anzsrc-for:0707 schema:inDefinedTermSet anzsrc-for:
191 schema:name Veterinary Sciences
192 rdf:type schema:DefinedTerm
193 sg:journal.1091998 schema:issn 0165-7380
194 1573-7446
195 schema:name Veterinary Research Communications
196 schema:publisher Springer Nature
197 rdf:type schema:Periodical
198 sg:person.01055366011.56 schema:affiliation grid-institutes:grid.412891.7
199 schema:familyName Gutiérrez-Chávez
200 schema:givenName Abner J.
201 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01055366011.56
202 rdf:type schema:Person
203 sg:person.01233266671.23 schema:affiliation grid-institutes:grid.412891.7
204 schema:familyName Valencia-Posadas
205 schema:givenName Mauricio
206 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01233266671.23
207 rdf:type schema:Person
208 sg:person.01350164416.17 schema:affiliation grid-institutes:grid.412891.7
209 schema:familyName Lechuga-Arana
210 schema:givenName Alma A.
211 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01350164416.17
212 rdf:type schema:Person
213 sg:person.01357513333.40 schema:affiliation grid-institutes:grid.412891.7
214 schema:familyName León-Galván
215 schema:givenName Ma. Fabiola
216 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01357513333.40
217 rdf:type schema:Person
218 sg:person.0727577161.69 schema:affiliation grid-institutes:grid.418275.d
219 schema:familyName González-Marrero
220 schema:givenName Joaquín
221 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0727577161.69
222 rdf:type schema:Person
223 sg:person.0745304467.10 schema:affiliation grid-institutes:grid.412891.7
224 schema:familyName Barboza-Corona
225 schema:givenName José E.
226 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0745304467.10
227 rdf:type schema:Person
228 sg:pub.10.1007/978-1-60327-164-6_1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004942703
229 https://doi.org/10.1007/978-1-60327-164-6_1
230 rdf:type schema:CreativeWork
231 sg:pub.10.1007/bf02931564 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044703101
232 https://doi.org/10.1007/bf02931564
233 rdf:type schema:CreativeWork
234 sg:pub.10.1007/s00284-015-0958-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043812822
235 https://doi.org/10.1007/s00284-015-0958-8
236 rdf:type schema:CreativeWork
237 sg:pub.10.1007/s00705-011-1160-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010333258
238 https://doi.org/10.1007/s00705-011-1160-3
239 rdf:type schema:CreativeWork
240 sg:pub.10.1007/s13594-014-0195-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003592157
241 https://doi.org/10.1007/s13594-014-0195-0
242 rdf:type schema:CreativeWork
243 sg:pub.10.1038/srep25063 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025404478
244 https://doi.org/10.1038/srep25063
245 rdf:type schema:CreativeWork
246 sg:pub.10.1186/1743-422x-9-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041849667
247 https://doi.org/10.1186/1743-422x-9-9
248 rdf:type schema:CreativeWork
249 grid-institutes:None schema:alternateName Consultoría en Biotecnología, Bioingeniería y Servicios Asociados, S. A. de C. V. (COBBYSA), 37548, San Miguel León, Guanajuato, Mexico
250 Estudiante de la Unidad Profesional Interdisciplinaria de Ingeniería Campus Guanajuato, Ingeniería Farmacéutica, IPN, 36275, Silao, Guanajuato, Mexico
251 schema:name Consultoría en Biotecnología, Bioingeniería y Servicios Asociados, S. A. de C. V. (COBBYSA), 37548, San Miguel León, Guanajuato, Mexico
252 Estudiante de la Unidad Profesional Interdisciplinaria de Ingeniería Campus Guanajuato, Ingeniería Farmacéutica, IPN, 36275, Silao, Guanajuato, Mexico
253 rdf:type schema:Organization
254 grid-institutes:grid.412891.7 schema:alternateName Campus Irapuato-Salamanca, División de Ciencias de la Vida, Departamento de Alimentos, Universidad de Guanajuato, 36500, Irapuato, Guanajuato, Mexico
255 Campus Irapuato-Salamanca, División de Ciencias de la Vida, Departamento de Veterinaria y Zootecnia, Universidad de Guanajuato, 36500, Irapuato, Guanajuato, Mexico
256 Estudiante de la Universidad de Guanajuato, Campus Irapuato-Salamanca, División de Ciencias de la Vida, Posgrado en Biociencias, 36500, Irapuato, Guanajuato, Mexico
257 schema:name Campus Irapuato-Salamanca, División de Ciencias de la Vida, Departamento de Alimentos, Universidad de Guanajuato, 36500, Irapuato, Guanajuato, Mexico
258 Campus Irapuato-Salamanca, División de Ciencias de la Vida, Departamento de Veterinaria y Zootecnia, Universidad de Guanajuato, 36500, Irapuato, Guanajuato, Mexico
259 Campus Irapuato-Salamanca, División de Ciencias de la Vida, Posgrado en Biociencias, Universidad de Guanajuato, 36500, Irapuato, Guanajuato, Mexico
260 Estudiante de la Universidad de Guanajuato, Campus Irapuato-Salamanca, División de Ciencias de la Vida, Posgrado en Biociencias, 36500, Irapuato, Guanajuato, Mexico
261 rdf:type schema:Organization
262 grid-institutes:grid.418275.d schema:alternateName Instituto Politécnico Nacional, UPIIG, 36275, Silao, Guanajuato, Mexico
263 schema:name Instituto Politécnico Nacional, UPIIG, 36275, Silao, Guanajuato, Mexico
264 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...