Antibiotic susceptibility of Staphylococcus aureus isolated from subclinical bovine mastitis cases and in vitro efficacy of bacteriophage View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2018-07-24

AUTHORS

Diego F. Varela-Ortiz, José E. Barboza-Corona, Joaquín González-Marrero, Ma. Fabiola León-Galván, Mauricio Valencia-Posadas, Alma A. Lechuga-Arana, Cynthia G. Sánchez-Felipe, Fernanda Ledezma-García, Abner J. Gutiérrez-Chávez

ABSTRACT

Staphylococcus aureus is an opportunistic pathogen that may cause severe infections in livestock, and represents the major cause of mastitis in dairy cows. Currently, instead of using antibiotics, new strategies are sought to reduce this clinical health problem. The aim of this study was to determine the efficacy of phage therapy to kill S. aureus strains obtained from farms located at the State of Guanajuato, México. Thirty-six S. aureus strains from cow milk with subclinical mastitis were isolated and identified, and the susceptibility to antibiotics and four phages also isolated in this work was tested. It was found that more of 90% of S. aureus isolates were not susceptible to six or more antibiotics, and 100% were resistant to penicillin, dicloxacillin, cefotaxime, ampicillin and cephalothin, and 81 and 77%, to tetracycline and cefuroxime, respectively. Fortunately, 100% of S. aureus isolates were susceptible to phages used in this work, which was detected as clear zones using specific phage. It was shown for the first time, that phages used in this study are active against pathogenic S. aureus and might be incorporated into the therapy as an important tool for the control of staphylococcal bovine mastitis, specially to antibiotic-resistant S. aureus strains isolated in farm located at the state of Guanajuato, México; and its use might be extended to other regions inside or outside the country. More... »

PAGES

243-250

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11259-018-9730-4

DOI

http://dx.doi.org/10.1007/s11259-018-9730-4

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1105806582

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30043292


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/07", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Agricultural and Veterinary Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0707", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Veterinary Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Anti-Bacterial Agents", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Bacteriophages", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cattle", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Drug Resistance, Bacterial", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "In Vitro Techniques", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mastitis, Bovine", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mexico", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Staphylococcal Infections", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Staphylococcus aureus", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Estudiante de la Unidad Profesional Interdisciplinaria de Ingenier\u00eda Campus Guanajuato, Ingenier\u00eda Farmac\u00e9utica, IPN, 36275, Silao, Guanajuato, Mexico", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Estudiante de la Unidad Profesional Interdisciplinaria de Ingenier\u00eda Campus Guanajuato, Ingenier\u00eda Farmac\u00e9utica, IPN, 36275, Silao, Guanajuato, Mexico"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Varela-Ortiz", 
        "givenName": "Diego F.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Campus Irapuato-Salamanca, Divisi\u00f3n de Ciencias de la Vida, Departamento de Alimentos, Universidad de Guanajuato, 36500, Irapuato, Guanajuato, Mexico", 
          "id": "http://www.grid.ac/institutes/grid.412891.7", 
          "name": [
            "Campus Irapuato-Salamanca, Divisi\u00f3n de Ciencias de la Vida, Posgrado en Biociencias, Universidad de Guanajuato, 36500, Irapuato, Guanajuato, Mexico", 
            "Campus Irapuato-Salamanca, Divisi\u00f3n de Ciencias de la Vida, Departamento de Alimentos, Universidad de Guanajuato, 36500, Irapuato, Guanajuato, Mexico"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Barboza-Corona", 
        "givenName": "Jos\u00e9 E.", 
        "id": "sg:person.0745304467.10", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0745304467.10"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Instituto Polit\u00e9cnico Nacional, UPIIG, 36275, Silao, Guanajuato, Mexico", 
          "id": "http://www.grid.ac/institutes/grid.418275.d", 
          "name": [
            "Instituto Polit\u00e9cnico Nacional, UPIIG, 36275, Silao, Guanajuato, Mexico"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gonz\u00e1lez-Marrero", 
        "givenName": "Joaqu\u00edn", 
        "id": "sg:person.0727577161.69", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0727577161.69"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Campus Irapuato-Salamanca, Divisi\u00f3n de Ciencias de la Vida, Departamento de Alimentos, Universidad de Guanajuato, 36500, Irapuato, Guanajuato, Mexico", 
          "id": "http://www.grid.ac/institutes/grid.412891.7", 
          "name": [
            "Campus Irapuato-Salamanca, Divisi\u00f3n de Ciencias de la Vida, Posgrado en Biociencias, Universidad de Guanajuato, 36500, Irapuato, Guanajuato, Mexico", 
            "Campus Irapuato-Salamanca, Divisi\u00f3n de Ciencias de la Vida, Departamento de Alimentos, Universidad de Guanajuato, 36500, Irapuato, Guanajuato, Mexico"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Le\u00f3n-Galv\u00e1n", 
        "givenName": "Ma. Fabiola", 
        "id": "sg:person.01357513333.40", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01357513333.40"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Campus Irapuato-Salamanca, Divisi\u00f3n de Ciencias de la Vida, Departamento de Veterinaria y Zootecnia, Universidad de Guanajuato, 36500, Irapuato, Guanajuato, Mexico", 
          "id": "http://www.grid.ac/institutes/grid.412891.7", 
          "name": [
            "Campus Irapuato-Salamanca, Divisi\u00f3n de Ciencias de la Vida, Posgrado en Biociencias, Universidad de Guanajuato, 36500, Irapuato, Guanajuato, Mexico", 
            "Campus Irapuato-Salamanca, Divisi\u00f3n de Ciencias de la Vida, Departamento de Veterinaria y Zootecnia, Universidad de Guanajuato, 36500, Irapuato, Guanajuato, Mexico"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Valencia-Posadas", 
        "givenName": "Mauricio", 
        "id": "sg:person.01233266671.23", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01233266671.23"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Estudiante de la Universidad de Guanajuato, Campus Irapuato-Salamanca, Divisi\u00f3n de Ciencias de la Vida, Posgrado en Biociencias, 36500, Irapuato, Guanajuato, Mexico", 
          "id": "http://www.grid.ac/institutes/grid.412891.7", 
          "name": [
            "Estudiante de la Universidad de Guanajuato, Campus Irapuato-Salamanca, Divisi\u00f3n de Ciencias de la Vida, Posgrado en Biociencias, 36500, Irapuato, Guanajuato, Mexico"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lechuga-Arana", 
        "givenName": "Alma A.", 
        "id": "sg:person.01350164416.17", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01350164416.17"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Consultor\u00eda en Biotecnolog\u00eda, Bioingenier\u00eda y Servicios Asociados, S. A. de C. V. (COBBYSA), 37548, San Miguel Le\u00f3n, Guanajuato, Mexico", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Consultor\u00eda en Biotecnolog\u00eda, Bioingenier\u00eda y Servicios Asociados, S. A. de C. V. (COBBYSA), 37548, San Miguel Le\u00f3n, Guanajuato, Mexico"
          ], 
          "type": "Organization"
        }, 
        "familyName": "S\u00e1nchez-Felipe", 
        "givenName": "Cynthia G.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Consultor\u00eda en Biotecnolog\u00eda, Bioingenier\u00eda y Servicios Asociados, S. A. de C. V. (COBBYSA), 37548, San Miguel Le\u00f3n, Guanajuato, Mexico", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Consultor\u00eda en Biotecnolog\u00eda, Bioingenier\u00eda y Servicios Asociados, S. A. de C. V. (COBBYSA), 37548, San Miguel Le\u00f3n, Guanajuato, Mexico"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ledezma-Garc\u00eda", 
        "givenName": "Fernanda", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Campus Irapuato-Salamanca, Divisi\u00f3n de Ciencias de la Vida, Departamento de Veterinaria y Zootecnia, Universidad de Guanajuato, 36500, Irapuato, Guanajuato, Mexico", 
          "id": "http://www.grid.ac/institutes/grid.412891.7", 
          "name": [
            "Campus Irapuato-Salamanca, Divisi\u00f3n de Ciencias de la Vida, Posgrado en Biociencias, Universidad de Guanajuato, 36500, Irapuato, Guanajuato, Mexico", 
            "Campus Irapuato-Salamanca, Divisi\u00f3n de Ciencias de la Vida, Departamento de Veterinaria y Zootecnia, Universidad de Guanajuato, 36500, Irapuato, Guanajuato, Mexico"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Guti\u00e9rrez-Ch\u00e1vez", 
        "givenName": "Abner J.", 
        "id": "sg:person.01055366011.56", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01055366011.56"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/srep25063", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025404478", 
          "https://doi.org/10.1038/srep25063"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02931564", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044703101", 
          "https://doi.org/10.1007/bf02931564"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s13594-014-0195-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003592157", 
          "https://doi.org/10.1007/s13594-014-0195-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00705-011-1160-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010333258", 
          "https://doi.org/10.1007/s00705-011-1160-3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00284-015-0958-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043812822", 
          "https://doi.org/10.1007/s00284-015-0958-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1743-422x-9-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041849667", 
          "https://doi.org/10.1186/1743-422x-9-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-1-60327-164-6_1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004942703", 
          "https://doi.org/10.1007/978-1-60327-164-6_1"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2018-07-24", 
    "datePublishedReg": "2018-07-24", 
    "description": "Staphylococcus aureus is an opportunistic pathogen that may cause severe infections in livestock, and represents the major cause of mastitis in dairy cows. Currently, instead of using antibiotics, new strategies are sought to reduce this clinical health problem. The aim of this study was to determine the efficacy of phage therapy to kill S. aureus strains obtained from farms located at the State of Guanajuato, M\u00e9xico. Thirty-six S. aureus strains from cow milk with subclinical mastitis were isolated and identified, and the susceptibility to antibiotics and four phages also isolated in this work was tested. It was found that more of 90% of S. aureus isolates were not susceptible to six or more antibiotics, and 100% were resistant to penicillin, dicloxacillin, cefotaxime, ampicillin and cephalothin, and 81 and 77%, to tetracycline and cefuroxime, respectively. Fortunately, 100% of S. aureus isolates were susceptible to phages used in this work, which was detected as clear zones using specific phage. It was shown for the first time, that phages used in this study are active against pathogenic S. aureus and might be incorporated into the therapy as an important tool for the control of staphylococcal bovine mastitis, specially to antibiotic-resistant S. aureus strains isolated in farm located at the state of Guanajuato, M\u00e9xico; and its use might be extended to other regions inside or outside the country.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/s11259-018-9730-4", 
    "inLanguage": "en", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1091998", 
        "issn": [
          "0165-7380", 
          "1573-7446"
        ], 
        "name": "Veterinary Research Communications", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "3", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "42"
      }
    ], 
    "keywords": [
      "aureus isolates", 
      "clinical health problems", 
      "subclinical bovine mastitis cases", 
      "staphylococcal bovine mastitis", 
      "Staphylococcus aureus", 
      "efficacy of bacteriophage", 
      "severe infections", 
      "more antibiotics", 
      "antibiotic susceptibility", 
      "health problems", 
      "major cause", 
      "bovine mastitis cases", 
      "antibiotics", 
      "phage therapy", 
      "therapy", 
      "opportunistic pathogen", 
      "bovine mastitis", 
      "mastitis cases", 
      "aureus", 
      "cow's milk", 
      "efficacy", 
      "mastitis", 
      "subclinical mastitis", 
      "dairy cows", 
      "clear zone", 
      "susceptibility", 
      "cefuroxime", 
      "infection", 
      "isolates", 
      "cefotaxime", 
      "cephalothin", 
      "penicillin", 
      "ampicillin", 
      "new strategy", 
      "specific phages", 
      "study", 
      "dicloxacillin", 
      "cause", 
      "tetracycline", 
      "aim", 
      "pathogens", 
      "milk", 
      "state of Guanajuato", 
      "important tool", 
      "cows", 
      "control", 
      "phages", 
      "cases", 
      "first time", 
      "use", 
      "strategies", 
      "time", 
      "countries", 
      "bacteriophages", 
      "farms", 
      "state", 
      "region", 
      "tool", 
      "Guanajuato", 
      "livestock", 
      "M\u00e9xico", 
      "problem", 
      "work", 
      "zone"
    ], 
    "name": "Antibiotic susceptibility of Staphylococcus aureus isolated from subclinical bovine mastitis cases and in vitro efficacy of bacteriophage", 
    "pagination": "243-250", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1105806582"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s11259-018-9730-4"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30043292"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s11259-018-9730-4", 
      "https://app.dimensions.ai/details/publication/pub.1105806582"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2021-12-01T19:42", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20211201/entities/gbq_results/article/article_790.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/s11259-018-9730-4"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s11259-018-9730-4'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s11259-018-9730-4'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s11259-018-9730-4'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s11259-018-9730-4'


 

This table displays all metadata directly associated to this object as RDF triples.

264 TRIPLES      22 PREDICATES      108 URIs      93 LITERALS      18 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s11259-018-9730-4 schema:about N3230a292f8f940dbb274f90846681393
2 N324df3d3b2994f8db4052b66d8a8b726
3 N3f739459b36b49ffbd578e81978c36e7
4 N51805f0c2620492bbb32d33477891961
5 N77d12f452d2e47a2bc140eb2885f4913
6 N9445b840b0f7437f999386c7176783b2
7 Nb0cfa5b0926644a39f2e2f3a6af0cff5
8 Nd491fd84b60141b0b222446c22e216d5
9 Nd5fe0fb2ddfc45339d173ae794b6b6dd
10 Nda1b425380bc4e609b1fda97b2c2911e
11 Ne21610a893f148f3b1e8cf16686585f9
12 anzsrc-for:07
13 anzsrc-for:0707
14 schema:author Nb769370ddff94b3fb1a5f96f44414204
15 schema:citation sg:pub.10.1007/978-1-60327-164-6_1
16 sg:pub.10.1007/bf02931564
17 sg:pub.10.1007/s00284-015-0958-8
18 sg:pub.10.1007/s00705-011-1160-3
19 sg:pub.10.1007/s13594-014-0195-0
20 sg:pub.10.1038/srep25063
21 sg:pub.10.1186/1743-422x-9-9
22 schema:datePublished 2018-07-24
23 schema:datePublishedReg 2018-07-24
24 schema:description Staphylococcus aureus is an opportunistic pathogen that may cause severe infections in livestock, and represents the major cause of mastitis in dairy cows. Currently, instead of using antibiotics, new strategies are sought to reduce this clinical health problem. The aim of this study was to determine the efficacy of phage therapy to kill S. aureus strains obtained from farms located at the State of Guanajuato, México. Thirty-six S. aureus strains from cow milk with subclinical mastitis were isolated and identified, and the susceptibility to antibiotics and four phages also isolated in this work was tested. It was found that more of 90% of S. aureus isolates were not susceptible to six or more antibiotics, and 100% were resistant to penicillin, dicloxacillin, cefotaxime, ampicillin and cephalothin, and 81 and 77%, to tetracycline and cefuroxime, respectively. Fortunately, 100% of S. aureus isolates were susceptible to phages used in this work, which was detected as clear zones using specific phage. It was shown for the first time, that phages used in this study are active against pathogenic S. aureus and might be incorporated into the therapy as an important tool for the control of staphylococcal bovine mastitis, specially to antibiotic-resistant S. aureus strains isolated in farm located at the state of Guanajuato, México; and its use might be extended to other regions inside or outside the country.
25 schema:genre article
26 schema:inLanguage en
27 schema:isAccessibleForFree false
28 schema:isPartOf N8193433982e54540a4adba350c26b3be
29 Nce87e792a8254f74b0b6a3a59d5afc47
30 sg:journal.1091998
31 schema:keywords Guanajuato
32 México
33 Staphylococcus aureus
34 aim
35 ampicillin
36 antibiotic susceptibility
37 antibiotics
38 aureus
39 aureus isolates
40 bacteriophages
41 bovine mastitis
42 bovine mastitis cases
43 cases
44 cause
45 cefotaxime
46 cefuroxime
47 cephalothin
48 clear zone
49 clinical health problems
50 control
51 countries
52 cow's milk
53 cows
54 dairy cows
55 dicloxacillin
56 efficacy
57 efficacy of bacteriophage
58 farms
59 first time
60 health problems
61 important tool
62 infection
63 isolates
64 livestock
65 major cause
66 mastitis
67 mastitis cases
68 milk
69 more antibiotics
70 new strategy
71 opportunistic pathogen
72 pathogens
73 penicillin
74 phage therapy
75 phages
76 problem
77 region
78 severe infections
79 specific phages
80 staphylococcal bovine mastitis
81 state
82 state of Guanajuato
83 strategies
84 study
85 subclinical bovine mastitis cases
86 subclinical mastitis
87 susceptibility
88 tetracycline
89 therapy
90 time
91 tool
92 use
93 work
94 zone
95 schema:name Antibiotic susceptibility of Staphylococcus aureus isolated from subclinical bovine mastitis cases and in vitro efficacy of bacteriophage
96 schema:pagination 243-250
97 schema:productId N3392d4be811344c69d403fdcd2d96776
98 N420e46dc34ef4b0b95a951c1327bdbcb
99 N591132d9abd04c75b8c64be5e2c03de4
100 schema:sameAs https://app.dimensions.ai/details/publication/pub.1105806582
101 https://doi.org/10.1007/s11259-018-9730-4
102 schema:sdDatePublished 2021-12-01T19:42
103 schema:sdLicense https://scigraph.springernature.com/explorer/license/
104 schema:sdPublisher N9278c88488b1456082193f9778db0c15
105 schema:url https://doi.org/10.1007/s11259-018-9730-4
106 sgo:license sg:explorer/license/
107 sgo:sdDataset articles
108 rdf:type schema:ScholarlyArticle
109 N2e267941567a4488bd0c11ea16a70a3c rdf:first sg:person.01350164416.17
110 rdf:rest N31379b31eab64c2e8a6a1376fd18a016
111 N31379b31eab64c2e8a6a1376fd18a016 rdf:first N901188e7d9a14cc583cf22bd0934e611
112 rdf:rest N93e801c90022482aa1c132d42ae07517
113 N3230a292f8f940dbb274f90846681393 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
114 schema:name In Vitro Techniques
115 rdf:type schema:DefinedTerm
116 N324df3d3b2994f8db4052b66d8a8b726 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
117 schema:name Staphylococcal Infections
118 rdf:type schema:DefinedTerm
119 N3392d4be811344c69d403fdcd2d96776 schema:name doi
120 schema:value 10.1007/s11259-018-9730-4
121 rdf:type schema:PropertyValue
122 N3f739459b36b49ffbd578e81978c36e7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
123 schema:name Cattle
124 rdf:type schema:DefinedTerm
125 N420e46dc34ef4b0b95a951c1327bdbcb schema:name dimensions_id
126 schema:value pub.1105806582
127 rdf:type schema:PropertyValue
128 N51805f0c2620492bbb32d33477891961 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
129 schema:name Mastitis, Bovine
130 rdf:type schema:DefinedTerm
131 N591132d9abd04c75b8c64be5e2c03de4 schema:name pubmed_id
132 schema:value 30043292
133 rdf:type schema:PropertyValue
134 N70a4ed818b42482e9f37024d5caa24bc rdf:first sg:person.0727577161.69
135 rdf:rest Nae7cf406cca7402e83c6626d4fb3186b
136 N735ffa279285477583f27f53ce1522c0 schema:affiliation grid-institutes:None
137 schema:familyName Varela-Ortiz
138 schema:givenName Diego F.
139 rdf:type schema:Person
140 N76de3cb000254dc5a14a9ee883092146 rdf:first sg:person.0745304467.10
141 rdf:rest N70a4ed818b42482e9f37024d5caa24bc
142 N77d12f452d2e47a2bc140eb2885f4913 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
143 schema:name Mexico
144 rdf:type schema:DefinedTerm
145 N8193433982e54540a4adba350c26b3be schema:issueNumber 3
146 rdf:type schema:PublicationIssue
147 N901188e7d9a14cc583cf22bd0934e611 schema:affiliation grid-institutes:None
148 schema:familyName Sánchez-Felipe
149 schema:givenName Cynthia G.
150 rdf:type schema:Person
151 N9278c88488b1456082193f9778db0c15 schema:name Springer Nature - SN SciGraph project
152 rdf:type schema:Organization
153 N93036592d8f447c185606e86720666ad rdf:first sg:person.01233266671.23
154 rdf:rest N2e267941567a4488bd0c11ea16a70a3c
155 N93e801c90022482aa1c132d42ae07517 rdf:first Nbe478824c9ce42c8a7941523263c3230
156 rdf:rest Nbfad0e85e6a8428eae61f73b9b8ab082
157 N9445b840b0f7437f999386c7176783b2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
158 schema:name Staphylococcus aureus
159 rdf:type schema:DefinedTerm
160 Nae7cf406cca7402e83c6626d4fb3186b rdf:first sg:person.01357513333.40
161 rdf:rest N93036592d8f447c185606e86720666ad
162 Nb0cfa5b0926644a39f2e2f3a6af0cff5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
163 schema:name Anti-Bacterial Agents
164 rdf:type schema:DefinedTerm
165 Nb769370ddff94b3fb1a5f96f44414204 rdf:first N735ffa279285477583f27f53ce1522c0
166 rdf:rest N76de3cb000254dc5a14a9ee883092146
167 Nbe478824c9ce42c8a7941523263c3230 schema:affiliation grid-institutes:None
168 schema:familyName Ledezma-García
169 schema:givenName Fernanda
170 rdf:type schema:Person
171 Nbfad0e85e6a8428eae61f73b9b8ab082 rdf:first sg:person.01055366011.56
172 rdf:rest rdf:nil
173 Nce87e792a8254f74b0b6a3a59d5afc47 schema:volumeNumber 42
174 rdf:type schema:PublicationVolume
175 Nd491fd84b60141b0b222446c22e216d5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
176 schema:name Drug Resistance, Bacterial
177 rdf:type schema:DefinedTerm
178 Nd5fe0fb2ddfc45339d173ae794b6b6dd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
179 schema:name Animals
180 rdf:type schema:DefinedTerm
181 Nda1b425380bc4e609b1fda97b2c2911e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
182 schema:name Bacteriophages
183 rdf:type schema:DefinedTerm
184 Ne21610a893f148f3b1e8cf16686585f9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
185 schema:name Female
186 rdf:type schema:DefinedTerm
187 anzsrc-for:07 schema:inDefinedTermSet anzsrc-for:
188 schema:name Agricultural and Veterinary Sciences
189 rdf:type schema:DefinedTerm
190 anzsrc-for:0707 schema:inDefinedTermSet anzsrc-for:
191 schema:name Veterinary Sciences
192 rdf:type schema:DefinedTerm
193 sg:journal.1091998 schema:issn 0165-7380
194 1573-7446
195 schema:name Veterinary Research Communications
196 schema:publisher Springer Nature
197 rdf:type schema:Periodical
198 sg:person.01055366011.56 schema:affiliation grid-institutes:grid.412891.7
199 schema:familyName Gutiérrez-Chávez
200 schema:givenName Abner J.
201 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01055366011.56
202 rdf:type schema:Person
203 sg:person.01233266671.23 schema:affiliation grid-institutes:grid.412891.7
204 schema:familyName Valencia-Posadas
205 schema:givenName Mauricio
206 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01233266671.23
207 rdf:type schema:Person
208 sg:person.01350164416.17 schema:affiliation grid-institutes:grid.412891.7
209 schema:familyName Lechuga-Arana
210 schema:givenName Alma A.
211 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01350164416.17
212 rdf:type schema:Person
213 sg:person.01357513333.40 schema:affiliation grid-institutes:grid.412891.7
214 schema:familyName León-Galván
215 schema:givenName Ma. Fabiola
216 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01357513333.40
217 rdf:type schema:Person
218 sg:person.0727577161.69 schema:affiliation grid-institutes:grid.418275.d
219 schema:familyName González-Marrero
220 schema:givenName Joaquín
221 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0727577161.69
222 rdf:type schema:Person
223 sg:person.0745304467.10 schema:affiliation grid-institutes:grid.412891.7
224 schema:familyName Barboza-Corona
225 schema:givenName José E.
226 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0745304467.10
227 rdf:type schema:Person
228 sg:pub.10.1007/978-1-60327-164-6_1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004942703
229 https://doi.org/10.1007/978-1-60327-164-6_1
230 rdf:type schema:CreativeWork
231 sg:pub.10.1007/bf02931564 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044703101
232 https://doi.org/10.1007/bf02931564
233 rdf:type schema:CreativeWork
234 sg:pub.10.1007/s00284-015-0958-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043812822
235 https://doi.org/10.1007/s00284-015-0958-8
236 rdf:type schema:CreativeWork
237 sg:pub.10.1007/s00705-011-1160-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010333258
238 https://doi.org/10.1007/s00705-011-1160-3
239 rdf:type schema:CreativeWork
240 sg:pub.10.1007/s13594-014-0195-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003592157
241 https://doi.org/10.1007/s13594-014-0195-0
242 rdf:type schema:CreativeWork
243 sg:pub.10.1038/srep25063 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025404478
244 https://doi.org/10.1038/srep25063
245 rdf:type schema:CreativeWork
246 sg:pub.10.1186/1743-422x-9-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041849667
247 https://doi.org/10.1186/1743-422x-9-9
248 rdf:type schema:CreativeWork
249 grid-institutes:None schema:alternateName Consultoría en Biotecnología, Bioingeniería y Servicios Asociados, S. A. de C. V. (COBBYSA), 37548, San Miguel León, Guanajuato, Mexico
250 Estudiante de la Unidad Profesional Interdisciplinaria de Ingeniería Campus Guanajuato, Ingeniería Farmacéutica, IPN, 36275, Silao, Guanajuato, Mexico
251 schema:name Consultoría en Biotecnología, Bioingeniería y Servicios Asociados, S. A. de C. V. (COBBYSA), 37548, San Miguel León, Guanajuato, Mexico
252 Estudiante de la Unidad Profesional Interdisciplinaria de Ingeniería Campus Guanajuato, Ingeniería Farmacéutica, IPN, 36275, Silao, Guanajuato, Mexico
253 rdf:type schema:Organization
254 grid-institutes:grid.412891.7 schema:alternateName Campus Irapuato-Salamanca, División de Ciencias de la Vida, Departamento de Alimentos, Universidad de Guanajuato, 36500, Irapuato, Guanajuato, Mexico
255 Campus Irapuato-Salamanca, División de Ciencias de la Vida, Departamento de Veterinaria y Zootecnia, Universidad de Guanajuato, 36500, Irapuato, Guanajuato, Mexico
256 Estudiante de la Universidad de Guanajuato, Campus Irapuato-Salamanca, División de Ciencias de la Vida, Posgrado en Biociencias, 36500, Irapuato, Guanajuato, Mexico
257 schema:name Campus Irapuato-Salamanca, División de Ciencias de la Vida, Departamento de Alimentos, Universidad de Guanajuato, 36500, Irapuato, Guanajuato, Mexico
258 Campus Irapuato-Salamanca, División de Ciencias de la Vida, Departamento de Veterinaria y Zootecnia, Universidad de Guanajuato, 36500, Irapuato, Guanajuato, Mexico
259 Campus Irapuato-Salamanca, División de Ciencias de la Vida, Posgrado en Biociencias, Universidad de Guanajuato, 36500, Irapuato, Guanajuato, Mexico
260 Estudiante de la Universidad de Guanajuato, Campus Irapuato-Salamanca, División de Ciencias de la Vida, Posgrado en Biociencias, 36500, Irapuato, Guanajuato, Mexico
261 rdf:type schema:Organization
262 grid-institutes:grid.418275.d schema:alternateName Instituto Politécnico Nacional, UPIIG, 36275, Silao, Guanajuato, Mexico
263 schema:name Instituto Politécnico Nacional, UPIIG, 36275, Silao, Guanajuato, Mexico
264 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...