Type 1 diabetes mellitus and hyperadrenocorticism in a ferret View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2010-06

AUTHORS

A. Boari, V. Papa, F. Di Silverio, G. Aste, D. Olivero, F. Rocconi

ABSTRACT

Diabetes mellitus (DM) was diagnosed in a 6-year-old neutered male ferret with polyuria/polydipsia, symmetrical alopecia, and weight loss. Laboratory tests revealed severe hyperglycemia, glucosuria, and increased steroid hormone profile. Abdominal ultrasound revealed a bilateral enlargement of the adrenal glands. Significant clinical improvement was achieved with insulin- and leuprolide acetate-based therapy. After 2 months of therapy, the ferret showed a severe ketoacidosis, and the owner decided to euthanize the animal. Histological findings revealed carcinoma of the left adrenal cortex and cortical hyperplasia of the right adrenal gland. Moderate, chronic, and active pancreatitis with a marked decrease in the number of beta-cells was also present. This is the first reported case of type 1 DM associated with hyperadrenocorticism and chronic pancreatitis in a ferret. More... »

PAGES

107-110

References to SciGraph publications

  • 2006. Diabetes Mellitus in ENCYCLOPEDIC REFERENCE OF GENOMICS AND PROTEOMICS IN MOLECULAR MEDICINE
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s11259-010-9369-2

    DOI

    http://dx.doi.org/10.1007/s11259-010-9369-2

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1030555363

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/20446034


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