Changes in metabolite, energy metabolism related enzyme activities and peripheral blood mononuclear cell (PBMC) Populations in beef heifers with two ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2007-09-12

AUTHORS

A. Mori, P. R. Kenyon, N. Mori, I. Yamamoto, Y. Tanaka, N. Suzuki, H. Tazaki, T. Ozawa, T. Hayashi, R. E. Hickson, S. T. Morris, H. Blair, T. Arai

ABSTRACT

Metabolite and immunoreactive insulin (IRI) concentrations, energy metabolism related enzymes activities and peripheral blood mononuclear cell (PBMC) populations were measured in blood of pregnant Angus heifers with differing liveweight change profiles (gaining or losing), in New Zealand to investigate the meanings of those parameters in the restricted feeding beef heifers. Beef heifers losing liveweight (−412 g/day) showed significantly lower concentrations of plasma IRI, and higher concentrations of plasma free fatty acid (FFA) than heifers gaining liveweight (483 g/day). The cytosolic and mitochondrial malate dehydrogenase (MDH) activities and MDH/lactate dehydrogenase (M/L) ratio in leukocytes of the liveweight losing heifers were significantly higher than those the liveweight gaining heifers. Percentages of cluster of differentiation (CD) 3 positive cells and natural killer (NK) cells in PBMC decreased significantly in the liveweight losing heifers compared to those in the liveweight gaining heifers. Plasma IRI and FFA concentrations, leukocyte cytosolic and mitochondrial MDH activities and CD3 positive and NK cell populations may be useful markers to evaluate metabolic conditions and immunity in the restricted feeding beef heifers. More... »

PAGES

159-166

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11259-007-9017-7

DOI

http://dx.doi.org/10.1007/s11259-007-9017-7

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1039846677

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/17849230


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