Hepatitis B reactivation in HBsAg-negative/HBcAb-positive patients receiving immunosuppressive therapy for glomerulonephritis: a retrospective analysis View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2016-12-28

AUTHORS

Jing Fang, Wenge Li, Xiangxin Peng, Zhao Tan, Min Tan, Cong Zhang, Wenbo Wang, Zhihong Xu, Gumin Zhou

ABSTRACT

PurposeThe aim of this study is to investigate the prevalence and risk factors for hepatitis B virus (HBV) reactivation in HBsAg-negative/HBcAb-positive patients receiving immunosuppressive therapy for glomerulonephritis.MethodsWe performed a retrospective study of 745 HBsAg-negative/HBcAb-positive patients undergoing immunosuppressive therapy for glomerulonephritis from years 2003 to 2012 at the department of nephrology, China-Japan Friendship Hospital, Beijing, China. The patients were divided into HBV reactivation group (n = 27) and non-HBV reactivation group (n = 718).ResultsThe prevalence of HBV reactivation in patients receiving immunosuppressive therapy for glomerulonephritis was up to 3.62% in serological status of HBsAg-negative/HBcAb-positive. HBV reactivation was associated with several findings: greater proportion of lupus nephritis (25.93 vs. 9.61%, p = 0.014), much higher percentage of HBsAb-negative (74.07 vs. 23.82%, p < 0.001), longer duration of immunosuppressive treatment (100 vs. 70.06%, p < 0.001), as well as more cases of combined immunosuppressant (92.59 vs. 61.56%, p = 0.001). After univariate and multivariate analysis, three variables remained as independent risk factors for HBV reactivation: serological status of HBsAb-negative (OR 8.375, 95% CI 3.674–19.776, p = 0.001), length of immunosuppressive treatment more than 1 year (OR 1.308, 95% CI 1.121–1.358, p = 0.024), and combined immunosuppressant (OR 6.342, 95% CI 1.675–30.166, p = 0.003).ConclusionsHBV reactivation is not uncommon in HBsAg-negative/HBcAb-positive glomerulonephritis patients treated with immunosuppressant, and the prevalence was up to 3.62%. Patients with serological status of HBsAb-negative, more than 1 year of immunosuppressive therapy, and combined immunosuppressant are independent risk factors for HBV reactivation. More... »

PAGES

475-482

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11255-016-1487-5

DOI

http://dx.doi.org/10.1007/s11255-016-1487-5

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1009194155

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/28032257


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "DNA, Viral", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Drug Therapy, Combination", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Glomerulonephritis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hepatitis B", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hepatitis B Core Antigens", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hepatitis B Surface Antigens", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hepatitis B virus", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Immunosuppressive Agents", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Retrospective Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Risk Factors", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Time Factors", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Virus Activation", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Nephrology, China-Japan Friendship Hospital, No. 2 East Yinghua Street, Chaoyang District, 100029, Beijing, China", 
          "id": "http://www.grid.ac/institutes/grid.415954.8", 
          "name": [
            "Department of Nephrology, China-Japan Friendship Hospital, No. 2 East Yinghua Street, Chaoyang District, 100029, Beijing, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fang", 
        "givenName": "Jing", 
        "id": "sg:person.0750716622.35", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0750716622.35"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Nephrology, China-Japan Friendship Hospital, No. 2 East Yinghua Street, Chaoyang District, 100029, Beijing, China", 
          "id": "http://www.grid.ac/institutes/grid.415954.8", 
          "name": [
            "Department of Nephrology, China-Japan Friendship Hospital, No. 2 East Yinghua Street, Chaoyang District, 100029, Beijing, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Li", 
        "givenName": "Wenge", 
        "id": "sg:person.0657737640.89", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0657737640.89"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Hepatology, China-Japan Friendship Hospital, Beijing, China", 
          "id": "http://www.grid.ac/institutes/grid.415954.8", 
          "name": [
            "Department of Hepatology, China-Japan Friendship Hospital, Beijing, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Peng", 
        "givenName": "Xiangxin", 
        "id": "sg:person.011273416265.28", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011273416265.28"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Nephrology, China-Japan Friendship Hospital, No. 2 East Yinghua Street, Chaoyang District, 100029, Beijing, China", 
          "id": "http://www.grid.ac/institutes/grid.415954.8", 
          "name": [
            "Department of Nephrology, China-Japan Friendship Hospital, No. 2 East Yinghua Street, Chaoyang District, 100029, Beijing, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tan", 
        "givenName": "Zhao", 
        "id": "sg:person.0774166240.01", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0774166240.01"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Nephrology, China-Japan Friendship Hospital, No. 2 East Yinghua Street, Chaoyang District, 100029, Beijing, China", 
          "id": "http://www.grid.ac/institutes/grid.415954.8", 
          "name": [
            "Department of Nephrology, China-Japan Friendship Hospital, No. 2 East Yinghua Street, Chaoyang District, 100029, Beijing, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tan", 
        "givenName": "Min", 
        "id": "sg:person.01021453055.14", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01021453055.14"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Nephrology, China-Japan Friendship Hospital, No. 2 East Yinghua Street, Chaoyang District, 100029, Beijing, China", 
          "id": "http://www.grid.ac/institutes/grid.415954.8", 
          "name": [
            "Department of Nephrology, China-Japan Friendship Hospital, No. 2 East Yinghua Street, Chaoyang District, 100029, Beijing, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Zhang", 
        "givenName": "Cong", 
        "id": "sg:person.01204014655.07", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01204014655.07"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Nephrology, China-Japan Friendship Hospital, No. 2 East Yinghua Street, Chaoyang District, 100029, Beijing, China", 
          "id": "http://www.grid.ac/institutes/grid.415954.8", 
          "name": [
            "Department of Nephrology, China-Japan Friendship Hospital, No. 2 East Yinghua Street, Chaoyang District, 100029, Beijing, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wang", 
        "givenName": "Wenbo", 
        "id": "sg:person.014261320265.66", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014261320265.66"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Nephrology, China-Japan Friendship Hospital, No. 2 East Yinghua Street, Chaoyang District, 100029, Beijing, China", 
          "id": "http://www.grid.ac/institutes/grid.415954.8", 
          "name": [
            "Department of Nephrology, China-Japan Friendship Hospital, No. 2 East Yinghua Street, Chaoyang District, 100029, Beijing, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Xu", 
        "givenName": "Zhihong", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Nephrology, China-Japan Friendship Hospital, No. 2 East Yinghua Street, Chaoyang District, 100029, Beijing, China", 
          "id": "http://www.grid.ac/institutes/grid.415954.8", 
          "name": [
            "Department of Nephrology, China-Japan Friendship Hospital, No. 2 East Yinghua Street, Chaoyang District, 100029, Beijing, China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Zhou", 
        "givenName": "Gumin", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/bmt.2010.70", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007689036", 
          "https://doi.org/10.1038/bmt.2010.70"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1471-2334-13-394", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007529388", 
          "https://doi.org/10.1186/1471-2334-13-394"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00277-009-0806-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004477070", 
          "https://doi.org/10.1007/s00277-009-0806-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00277-012-1405-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045742837", 
          "https://doi.org/10.1007/s00277-012-1405-6"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2016-12-28", 
    "datePublishedReg": "2016-12-28", 
    "description": "PurposeThe aim of this study is to investigate the prevalence and risk factors for hepatitis B virus (HBV) reactivation in HBsAg-negative/HBcAb-positive patients receiving immunosuppressive therapy for glomerulonephritis.MethodsWe performed a retrospective study of 745 HBsAg-negative/HBcAb-positive patients undergoing immunosuppressive therapy for glomerulonephritis from years 2003 to 2012 at the department of nephrology, China-Japan Friendship Hospital, Beijing, China. The patients were divided into HBV reactivation group (n\u00a0=\u00a027) and non-HBV reactivation group (n\u00a0=\u00a0718).ResultsThe prevalence of HBV reactivation in patients receiving immunosuppressive therapy for glomerulonephritis was up to 3.62% in serological status of HBsAg-negative/HBcAb-positive. HBV reactivation was associated with several findings: greater proportion of lupus nephritis (25.93 vs. 9.61%, p\u00a0=\u00a00.014), much higher percentage of HBsAb-negative (74.07 vs. 23.82%, p\u00a0<\u00a00.001), longer duration of immunosuppressive treatment (100 vs. 70.06%, p\u00a0<\u00a00.001), as well as more cases of combined immunosuppressant (92.59 vs. 61.56%, p\u00a0=\u00a00.001). After univariate and multivariate analysis, three variables remained as independent risk factors for HBV reactivation: serological status of HBsAb-negative (OR 8.375, 95% CI 3.674\u201319.776, p\u00a0=\u00a00.001), length of immunosuppressive treatment more than 1\u00a0year (OR 1.308, 95% CI 1.121\u20131.358, p\u00a0=\u00a00.024), and combined immunosuppressant (OR 6.342, 95% CI 1.675\u201330.166, p\u00a0=\u00a00.003).ConclusionsHBV reactivation is not uncommon in HBsAg-negative/HBcAb-positive glomerulonephritis patients treated with immunosuppressant, and the prevalence was up to 3.62%. Patients with serological status of HBsAb-negative, more than 1\u00a0year of immunosuppressive therapy, and combined immunosuppressant are independent risk factors for HBV reactivation.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/s11255-016-1487-5", 
    "inLanguage": "en", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1014320", 
        "issn": [
          "0924-8455", 
          "1573-7306"
        ], 
        "name": "International Urology and Nephrology", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "3", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "49"
      }
    ], 
    "keywords": [
      "HBcAb-positive patients", 
      "independent risk factor", 
      "immunosuppressive therapy", 
      "HBV reactivation", 
      "risk factors", 
      "serological status", 
      "immunosuppressive treatment", 
      "reactivation group", 
      "hepatitis B virus reactivation", 
      "China-Japan Friendship Hospital", 
      "hepatitis B reactivation", 
      "Department of Nephrology", 
      "virus reactivation", 
      "lupus nephritis", 
      "glomerulonephritis patients", 
      "retrospective study", 
      "retrospective analysis", 
      "HBsAg", 
      "patients", 
      "glomerulonephritis", 
      "multivariate analysis", 
      "therapy", 
      "immunosuppressants", 
      "more cases", 
      "HBsAb", 
      "longer duration", 
      "prevalence", 
      "reactivation", 
      "high percentage", 
      "greater proportion", 
      "treatment", 
      "status", 
      "HBcAb", 
      "nephritis", 
      "group", 
      "hospital", 
      "years", 
      "MethodsWe", 
      "factors", 
      "nephrology", 
      "univariate", 
      "years 2003", 
      "study", 
      "duration", 
      "Department", 
      "aim", 
      "findings", 
      "percentage", 
      "proportion", 
      "cases", 
      "analysis", 
      "variables", 
      "length", 
      "Beijing", 
      "China", 
      "B virus (HBV) reactivation", 
      "Friendship Hospital", 
      "HBV reactivation group", 
      "non-HBV reactivation group", 
      "ConclusionsHBV reactivation", 
      "HBcAb-positive glomerulonephritis patients", 
      "B reactivation"
    ], 
    "name": "Hepatitis B reactivation in HBsAg-negative/HBcAb-positive patients receiving immunosuppressive therapy for glomerulonephritis: a retrospective analysis", 
    "pagination": "475-482", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1009194155"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s11255-016-1487-5"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "28032257"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s11255-016-1487-5", 
      "https://app.dimensions.ai/details/publication/pub.1009194155"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2021-12-01T19:35", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20211201/entities/gbq_results/article/article_690.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/s11255-016-1487-5"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s11255-016-1487-5'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s11255-016-1487-5'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s11255-016-1487-5'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s11255-016-1487-5'


 

This table displays all metadata directly associated to this object as RDF triples.

264 TRIPLES      22 PREDICATES      109 URIs      97 LITERALS      24 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s11255-016-1487-5 schema:about N113634dc6b194b62a1ce0639f9e7a13f
2 N1177ba13d44240ca86ea7c77f4687d30
3 N11f89f8d670847c78b212c1deb0b7d66
4 N21d75b3008214184a7b8de4cb776b300
5 N2a1de775f8734a7cbe662cbb6e2bf21d
6 N3e96a6346095497bb5a830238c4b0dc9
7 N493cf1f09bf848d99dbf673f1889d4d3
8 N59caaa404ec943858a9a0c3c42cf2b2d
9 N5bfdfa68eea84af283a051aac16fc047
10 N8d62e42ec89a41c7ad4d809cf5f1ca1a
11 N93524f788e93418e806be000028df3e4
12 Nadda2c13a2b54008ae6ad99d41f864e8
13 Nb9f1a55dada547a189e942fd3bda5865
14 Nbea78b1e9e8e4ac59beb5f441585c099
15 Ncb7798a5e79e4e7ca2fee9a93d708bf5
16 Ne2d9f8c4e2fc43cda5c4bce055cf4559
17 Nff2e97798e834c3a8cd15bdaac8be383
18 anzsrc-for:11
19 anzsrc-for:1103
20 schema:author N71793cb038a74ea4999a2e848e69a091
21 schema:citation sg:pub.10.1007/s00277-009-0806-7
22 sg:pub.10.1007/s00277-012-1405-6
23 sg:pub.10.1038/bmt.2010.70
24 sg:pub.10.1186/1471-2334-13-394
25 schema:datePublished 2016-12-28
26 schema:datePublishedReg 2016-12-28
27 schema:description PurposeThe aim of this study is to investigate the prevalence and risk factors for hepatitis B virus (HBV) reactivation in HBsAg-negative/HBcAb-positive patients receiving immunosuppressive therapy for glomerulonephritis.MethodsWe performed a retrospective study of 745 HBsAg-negative/HBcAb-positive patients undergoing immunosuppressive therapy for glomerulonephritis from years 2003 to 2012 at the department of nephrology, China-Japan Friendship Hospital, Beijing, China. The patients were divided into HBV reactivation group (n = 27) and non-HBV reactivation group (n = 718).ResultsThe prevalence of HBV reactivation in patients receiving immunosuppressive therapy for glomerulonephritis was up to 3.62% in serological status of HBsAg-negative/HBcAb-positive. HBV reactivation was associated with several findings: greater proportion of lupus nephritis (25.93 vs. 9.61%, p = 0.014), much higher percentage of HBsAb-negative (74.07 vs. 23.82%, p < 0.001), longer duration of immunosuppressive treatment (100 vs. 70.06%, p < 0.001), as well as more cases of combined immunosuppressant (92.59 vs. 61.56%, p = 0.001). After univariate and multivariate analysis, three variables remained as independent risk factors for HBV reactivation: serological status of HBsAb-negative (OR 8.375, 95% CI 3.674–19.776, p = 0.001), length of immunosuppressive treatment more than 1 year (OR 1.308, 95% CI 1.121–1.358, p = 0.024), and combined immunosuppressant (OR 6.342, 95% CI 1.675–30.166, p = 0.003).ConclusionsHBV reactivation is not uncommon in HBsAg-negative/HBcAb-positive glomerulonephritis patients treated with immunosuppressant, and the prevalence was up to 3.62%. Patients with serological status of HBsAb-negative, more than 1 year of immunosuppressive therapy, and combined immunosuppressant are independent risk factors for HBV reactivation.
28 schema:genre article
29 schema:inLanguage en
30 schema:isAccessibleForFree false
31 schema:isPartOf N3c7c723611c94009b1f26cf0676414f6
32 Neeb77d1a47844271a905259830d378f3
33 sg:journal.1014320
34 schema:keywords B reactivation
35 B virus (HBV) reactivation
36 Beijing
37 China
38 China-Japan Friendship Hospital
39 ConclusionsHBV reactivation
40 Department
41 Department of Nephrology
42 Friendship Hospital
43 HBV reactivation
44 HBV reactivation group
45 HBcAb
46 HBcAb-positive glomerulonephritis patients
47 HBcAb-positive patients
48 HBsAb
49 HBsAg
50 MethodsWe
51 aim
52 analysis
53 cases
54 duration
55 factors
56 findings
57 glomerulonephritis
58 glomerulonephritis patients
59 greater proportion
60 group
61 hepatitis B reactivation
62 hepatitis B virus reactivation
63 high percentage
64 hospital
65 immunosuppressants
66 immunosuppressive therapy
67 immunosuppressive treatment
68 independent risk factor
69 length
70 longer duration
71 lupus nephritis
72 more cases
73 multivariate analysis
74 nephritis
75 nephrology
76 non-HBV reactivation group
77 patients
78 percentage
79 prevalence
80 proportion
81 reactivation
82 reactivation group
83 retrospective analysis
84 retrospective study
85 risk factors
86 serological status
87 status
88 study
89 therapy
90 treatment
91 univariate
92 variables
93 virus reactivation
94 years
95 years 2003
96 schema:name Hepatitis B reactivation in HBsAg-negative/HBcAb-positive patients receiving immunosuppressive therapy for glomerulonephritis: a retrospective analysis
97 schema:pagination 475-482
98 schema:productId N39367bd5fb8742e1a2c399f12c2fe920
99 Na1044c95db434b2cbcde5a2742db966b
100 Ne25d54d7a8164cda9c3e324b9e95df24
101 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009194155
102 https://doi.org/10.1007/s11255-016-1487-5
103 schema:sdDatePublished 2021-12-01T19:35
104 schema:sdLicense https://scigraph.springernature.com/explorer/license/
105 schema:sdPublisher N273d212935aa4a4aa8197ef0208fc6f3
106 schema:url https://doi.org/10.1007/s11255-016-1487-5
107 sgo:license sg:explorer/license/
108 sgo:sdDataset articles
109 rdf:type schema:ScholarlyArticle
110 N0162df5901d84e2b93df6088f89a7c85 schema:affiliation grid-institutes:grid.415954.8
111 schema:familyName Zhou
112 schema:givenName Gumin
113 rdf:type schema:Person
114 N113634dc6b194b62a1ce0639f9e7a13f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
115 schema:name Female
116 rdf:type schema:DefinedTerm
117 N1177ba13d44240ca86ea7c77f4687d30 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
118 schema:name DNA, Viral
119 rdf:type schema:DefinedTerm
120 N11f89f8d670847c78b212c1deb0b7d66 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
121 schema:name Hepatitis B virus
122 rdf:type schema:DefinedTerm
123 N21d75b3008214184a7b8de4cb776b300 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
124 schema:name Drug Therapy, Combination
125 rdf:type schema:DefinedTerm
126 N273d212935aa4a4aa8197ef0208fc6f3 schema:name Springer Nature - SN SciGraph project
127 rdf:type schema:Organization
128 N2a1de775f8734a7cbe662cbb6e2bf21d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
129 schema:name Retrospective Studies
130 rdf:type schema:DefinedTerm
131 N33188ab836cd4e3dbafbd32dc234e1f8 rdf:first sg:person.011273416265.28
132 rdf:rest N94aa61a7d99042bdbed7cb14114965e3
133 N39367bd5fb8742e1a2c399f12c2fe920 schema:name pubmed_id
134 schema:value 28032257
135 rdf:type schema:PropertyValue
136 N3c7c723611c94009b1f26cf0676414f6 schema:issueNumber 3
137 rdf:type schema:PublicationIssue
138 N3e96a6346095497bb5a830238c4b0dc9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
139 schema:name Virus Activation
140 rdf:type schema:DefinedTerm
141 N493cf1f09bf848d99dbf673f1889d4d3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
142 schema:name Hepatitis B
143 rdf:type schema:DefinedTerm
144 N4f54054ac7d743b6a25cb76896fce942 rdf:first N0162df5901d84e2b93df6088f89a7c85
145 rdf:rest rdf:nil
146 N59caaa404ec943858a9a0c3c42cf2b2d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
147 schema:name Adult
148 rdf:type schema:DefinedTerm
149 N5b2cc1201a214585b246283c7b60239e schema:affiliation grid-institutes:grid.415954.8
150 schema:familyName Xu
151 schema:givenName Zhihong
152 rdf:type schema:Person
153 N5bfdfa68eea84af283a051aac16fc047 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
154 schema:name Glomerulonephritis
155 rdf:type schema:DefinedTerm
156 N71793cb038a74ea4999a2e848e69a091 rdf:first sg:person.0750716622.35
157 rdf:rest Ne687b24869254af18a0a735c5a17405c
158 N8d62e42ec89a41c7ad4d809cf5f1ca1a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
159 schema:name Risk Factors
160 rdf:type schema:DefinedTerm
161 N93524f788e93418e806be000028df3e4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
162 schema:name Hepatitis B Core Antigens
163 rdf:type schema:DefinedTerm
164 N94aa61a7d99042bdbed7cb14114965e3 rdf:first sg:person.0774166240.01
165 rdf:rest Nd1fefa6a43a344b7ac5eee9dde008bce
166 Na1044c95db434b2cbcde5a2742db966b schema:name dimensions_id
167 schema:value pub.1009194155
168 rdf:type schema:PropertyValue
169 Nadda2c13a2b54008ae6ad99d41f864e8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
170 schema:name Middle Aged
171 rdf:type schema:DefinedTerm
172 Nb9f1a55dada547a189e942fd3bda5865 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
173 schema:name Time Factors
174 rdf:type schema:DefinedTerm
175 Nbdead6d5226140ae988db2b5fec6b6dd rdf:first sg:person.01204014655.07
176 rdf:rest Neaa7ed9c94584af096f6305ec3ae0c10
177 Nbea78b1e9e8e4ac59beb5f441585c099 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
178 schema:name Immunosuppressive Agents
179 rdf:type schema:DefinedTerm
180 Ncb7798a5e79e4e7ca2fee9a93d708bf5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
181 schema:name Hepatitis B Surface Antigens
182 rdf:type schema:DefinedTerm
183 Nd1fefa6a43a344b7ac5eee9dde008bce rdf:first sg:person.01021453055.14
184 rdf:rest Nbdead6d5226140ae988db2b5fec6b6dd
185 Ne25d54d7a8164cda9c3e324b9e95df24 schema:name doi
186 schema:value 10.1007/s11255-016-1487-5
187 rdf:type schema:PropertyValue
188 Ne2d9f8c4e2fc43cda5c4bce055cf4559 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
189 schema:name Male
190 rdf:type schema:DefinedTerm
191 Ne687b24869254af18a0a735c5a17405c rdf:first sg:person.0657737640.89
192 rdf:rest N33188ab836cd4e3dbafbd32dc234e1f8
193 Neaa7ed9c94584af096f6305ec3ae0c10 rdf:first sg:person.014261320265.66
194 rdf:rest Nf09949ca40d249c79dc96d96805f0187
195 Neeb77d1a47844271a905259830d378f3 schema:volumeNumber 49
196 rdf:type schema:PublicationVolume
197 Nf09949ca40d249c79dc96d96805f0187 rdf:first N5b2cc1201a214585b246283c7b60239e
198 rdf:rest N4f54054ac7d743b6a25cb76896fce942
199 Nff2e97798e834c3a8cd15bdaac8be383 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
200 schema:name Humans
201 rdf:type schema:DefinedTerm
202 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
203 schema:name Medical and Health Sciences
204 rdf:type schema:DefinedTerm
205 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
206 schema:name Clinical Sciences
207 rdf:type schema:DefinedTerm
208 sg:journal.1014320 schema:issn 0924-8455
209 1573-7306
210 schema:name International Urology and Nephrology
211 schema:publisher Springer Nature
212 rdf:type schema:Periodical
213 sg:person.01021453055.14 schema:affiliation grid-institutes:grid.415954.8
214 schema:familyName Tan
215 schema:givenName Min
216 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01021453055.14
217 rdf:type schema:Person
218 sg:person.011273416265.28 schema:affiliation grid-institutes:grid.415954.8
219 schema:familyName Peng
220 schema:givenName Xiangxin
221 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011273416265.28
222 rdf:type schema:Person
223 sg:person.01204014655.07 schema:affiliation grid-institutes:grid.415954.8
224 schema:familyName Zhang
225 schema:givenName Cong
226 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01204014655.07
227 rdf:type schema:Person
228 sg:person.014261320265.66 schema:affiliation grid-institutes:grid.415954.8
229 schema:familyName Wang
230 schema:givenName Wenbo
231 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014261320265.66
232 rdf:type schema:Person
233 sg:person.0657737640.89 schema:affiliation grid-institutes:grid.415954.8
234 schema:familyName Li
235 schema:givenName Wenge
236 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0657737640.89
237 rdf:type schema:Person
238 sg:person.0750716622.35 schema:affiliation grid-institutes:grid.415954.8
239 schema:familyName Fang
240 schema:givenName Jing
241 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0750716622.35
242 rdf:type schema:Person
243 sg:person.0774166240.01 schema:affiliation grid-institutes:grid.415954.8
244 schema:familyName Tan
245 schema:givenName Zhao
246 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0774166240.01
247 rdf:type schema:Person
248 sg:pub.10.1007/s00277-009-0806-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004477070
249 https://doi.org/10.1007/s00277-009-0806-7
250 rdf:type schema:CreativeWork
251 sg:pub.10.1007/s00277-012-1405-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045742837
252 https://doi.org/10.1007/s00277-012-1405-6
253 rdf:type schema:CreativeWork
254 sg:pub.10.1038/bmt.2010.70 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007689036
255 https://doi.org/10.1038/bmt.2010.70
256 rdf:type schema:CreativeWork
257 sg:pub.10.1186/1471-2334-13-394 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007529388
258 https://doi.org/10.1186/1471-2334-13-394
259 rdf:type schema:CreativeWork
260 grid-institutes:grid.415954.8 schema:alternateName Department of Hepatology, China-Japan Friendship Hospital, Beijing, China
261 Department of Nephrology, China-Japan Friendship Hospital, No. 2 East Yinghua Street, Chaoyang District, 100029, Beijing, China
262 schema:name Department of Hepatology, China-Japan Friendship Hospital, Beijing, China
263 Department of Nephrology, China-Japan Friendship Hospital, No. 2 East Yinghua Street, Chaoyang District, 100029, Beijing, China
264 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...