Churg–Strauss syndrome presenting with acute kidney injury in a case of primary focal segmental glomerulosclerosis View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2014-01

AUTHORS

Sachin B. Patil, Aruna V. Vanikar, Manoj R. Gumber, Vivek B. Kute, Pankaj R. Shah, Himanshu V. Patel, Hargovind L. Trivedi

ABSTRACT

Churg-Strauss syndrome (CSS) also called allergic granulomatosis and angiitis is a multisystem disorder. Churg-Strauss syndrome is defined as an eosinophil-rich, granulomatous inflammation involving the respiratory tract, along with necrotizing vasculitis affecting small- to medium-sized vessels, and is associated with asthma and eosinophilia. Renal involvement in CSS varies from 26 to 88 % but is usually of mild to moderate stage, and advanced renal failure is uncommon. We encountered an unusual case of 27-year-old man with asthma and primary focal segmental glomerulosclerosis diagnosed as CSS showing myeloperoxidase anti-neutrophil cytoplasmic antibody-associated acute kidney injury with crescentic glomerulonephritis. Patient responded to steroid and cyclophosphamide. Over a follow-up of 2 months, he has no hematuria/eosinophilia and serum creatinine of 2.3 mg/dL has decreased to 1.7 mg/dL. More... »

PAGES

211-215

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11255-012-0333-7

DOI

http://dx.doi.org/10.1007/s11255-012-0333-7

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1018329872

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/23229164


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