A one-center experience with pediatric percutaneous renal biopsy and histopathology in Ankara, Turkey View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2008-08-12

AUTHORS

Gülay Demircin, Ali Delibaş, Kenan Bek, Özlem Erdoğan, Mehmet Bülbül, Şahika Baysun, Ayşegül Oksal, Leyla Memiş, Ayşe Öner

ABSTRACT

In this study we evaluated the indications, complications, and the spectrum of histopathological results of percutaneous renal needle biopsy (PRNB) performed in our clinic. Between June 1990 and December 2006, 679 PRNBs were performed on native kidneys of 614 children (304 boys, 310 girls) with a mean age of 10.4 years. Most frequent indications for PRNB were nephrotic syndrome (47%), hematuria, and/or proteinuria (15.9%), acute renal failure (14.6%) and complex renal manifestations (18.9%). The overall complication rate was 15.2%. The most common complications were perirenal hematoma (12.4%) and macroscopic hematuria (2.6%). The most frequent histopathological group of diseases were glomerulopathies; these were diagnosed in 376 patients (61.2%) and included membranoproliferative glomerulonephritis (11.1%), mesangial proliferation (10.7%), diffuse proliferative glomerulonephritis (7.7%), and focal segmental glomerulosclerosis (7.3%) as the most frequent. The second most frequent group of histopathology was manifestations secondary to systemic diseases; these were shown in 195 patients (31.8%). Amyloidosis (11.4%) and Henoch–Schönlein nephritis (9.9%) made the majority of this group. In conclusion, our study demonstrated that PRNB is a safe procedure with usually transient complications showing the most frequent renal diseases that cause diagnostic and therapeutic difficulties for pediatric nephrologists. More... »

PAGES

933

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Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11255-008-9433-9

DOI

http://dx.doi.org/10.1007/s11255-008-9433-9

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1017431630

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/18696251


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87 patients
88 pediatric nephrologists
89 pediatric percutaneous renal biopsy
90 percutaneous renal biopsy
91 percutaneous renal needle biopsy
92 perirenal hematoma
93 procedure
94 proliferation
95 proliferative glomerulonephritis
96 proteinuria
97 rate
98 renal biopsy
99 renal disease
100 renal failure
101 renal manifestations
102 renal needle biopsy
103 results
104 safe procedure
105 segmental glomerulosclerosis
106 spectra
107 study
108 syndrome
109 systemic disease
110 therapeutic difficulties
111 transient complications
112 years
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