Comparison of rivaroxaban concentrations between Asians and Caucasians and their correlation with PT/INR View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2018-11

AUTHORS

Hobart Owen Ng Tsai, Janice Jia Ni Goh, Jernice Wan Xin Aw, Yingying Lin, Alan Yean Yip Fong, Lee Len Tiong, Doreen Su-Yin Tan

ABSTRACT

The objectives of this study are to compare steady-state trough (Cmin,ss) and peak (Cmax,ss) concentrations of rivaroxaban between Asians and Caucasians and to evaluate the relationship between rivaroxaban concentrations and prothrombin time/international normalized ratio (PT/INR). Recruited patients were advised on the time to take rivaroxaban. Cmin,ss and PT/INR were taken when patients arrived. Cmax,ss and PT/INR were drawn between 2 and 4 h later after the patient took rivaroxaban with food. Thirty patients were included in the analyses: 57% (n = 17) males and 43% (n = 13) females, 77% (n = 23) on 20 mg and 23% (n = 7) on 15 mg. Median PTtrough and PTpeak are moderately correlated with Cmin,ss (r2 = 0.43) and Cmax,ss (r2 = 0.49), respectively. Patients on 15 mg have lower Cmin,ss and Cmax,ss versus Caucasians [12 ng/ml vs. 57 ng/ml (Cmin,ss); 87 ng/ml vs. 229 ng/ml (Cmax,ss), p < 0.01 for both]. Patients on 20 mg also have lower Cmin,ss and Cmax,ss versus Caucasians [14 ng/ml vs. 44 ng/ml (Cmin,ss); 101 ng/ml vs. 249 ng/ml (Cmax,ss), p < 0.01 for both]. Subgroup analysis shows patients with BMI ≥ 30 have lower Cmax,ss than patients with BMI < 30 [80.47 ng/ml vs. 124 (p = 0.014)]. Cmin,ss and Cmax,ss were lower in Singaporeans than Caucasians. This may have an impact on the effectiveness of rivaroxaban in Singaporeans. Patients with higher BMI may not benefit similarly as patients with lower BMI. Lastly, the Dade Innovin reagent's measure of PT/INR is not sensitive towards changes in rivaroxaban concentrations. More... »

PAGES

541-548

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s11239-018-1726-y

DOI

http://dx.doi.org/10.1007/s11239-018-1726-y

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1106387762

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30155672


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1117", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Public Health and Health Services", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Khoo Teck Puat Hospital", 
          "id": "https://www.grid.ac/institutes/grid.415203.1", 
          "name": [
            "Department of Pharmacy, Khoo Teck Puat Hospital, 90 Yishun Central, 768828, Singapore, Singapore"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ng Tsai", 
        "givenName": "Hobart Owen", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Khoo Teck Puat Hospital", 
          "id": "https://www.grid.ac/institutes/grid.415203.1", 
          "name": [
            "Department of Pharmacy, Khoo Teck Puat Hospital, 90 Yishun Central, 768828, Singapore, Singapore"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Goh", 
        "givenName": "Janice Jia Ni", 
        "id": "sg:person.010116702675.16", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010116702675.16"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Khoo Teck Puat Hospital", 
          "id": "https://www.grid.ac/institutes/grid.415203.1", 
          "name": [
            "Department of Pharmacy, Khoo Teck Puat Hospital, 90 Yishun Central, 768828, Singapore, Singapore"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Aw", 
        "givenName": "Jernice Wan Xin", 
        "id": "sg:person.016236004310.40", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016236004310.40"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Khoo Teck Puat Hospital", 
          "id": "https://www.grid.ac/institutes/grid.415203.1", 
          "name": [
            "Department of Pharmacy, Khoo Teck Puat Hospital, 90 Yishun Central, 768828, Singapore, Singapore"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lin", 
        "givenName": "Yingying", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Sarawak General Hospital", 
          "id": "https://www.grid.ac/institutes/grid.415281.b", 
          "name": [
            "Consultant Cardiologist, Sarawak Heart Centre, Kuching - Samarahan Expressway, 94300, Kota Samarahan, Sarawak, Malaysia", 
            "Clinical Research Centre, Sarawak General Hospital, Jalan Hospital, 93586, Kuching, Sarawak, Malaysia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fong", 
        "givenName": "Alan Yean Yip", 
        "id": "sg:person.016423636335.12", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016423636335.12"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Sarawak General Hospital", 
          "id": "https://www.grid.ac/institutes/grid.415281.b", 
          "name": [
            "Clinical Research Centre, Sarawak General Hospital, Jalan Hospital, 93586, Kuching, Sarawak, Malaysia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tiong", 
        "givenName": "Lee Len", 
        "id": "sg:person.01255114517.29", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01255114517.29"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Khoo Teck Puat Hospital", 
          "id": "https://www.grid.ac/institutes/grid.415203.1", 
          "name": [
            "Department of Pharmacy, Khoo Teck Puat Hospital, 90 Yishun Central, 768828, Singapore, Singapore"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tan", 
        "givenName": "Doreen Su-Yin", 
        "id": "sg:person.0654504306.05", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0654504306.05"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1056/nejmoa1300615", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006495123"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2125.2009.03390.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015814013"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.gpb.2016.03.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019579079"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11239-015-1317-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023938710", 
          "https://doi.org/10.1007/s11239-015-1317-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11239-015-1317-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023938710", 
          "https://doi.org/10.1007/s11239-015-1317-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2133/dmpk.dmpk-12-rg-034", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024029267"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/eurheartj/ehv466", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026416125"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3109/0886022x.2011.605980", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029965769"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s40262-013-0100-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037310382", 
          "https://doi.org/10.1007/s40262-013-0100-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s40262-013-0100-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037310382", 
          "https://doi.org/10.1007/s40262-013-0100-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s40262-013-0100-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037310382", 
          "https://doi.org/10.1007/s40262-013-0100-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1253/circj.cj-12-0454", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045133504"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jacc.2013.07.104", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050091443"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1477-9560-11-11", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050975774", 
          "https://doi.org/10.1186/1477-9560-11-11"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa1009638", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051578846"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2174/1574884708666131111204658", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1069214254"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00228-018-2450-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1101719494", 
          "https://doi.org/10.1007/s00228-018-2450-4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00228-018-2450-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1101719494", 
          "https://doi.org/10.1007/s00228-018-2450-4"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2018-11", 
    "datePublishedReg": "2018-11-01", 
    "description": "The objectives of this study are to compare steady-state trough (Cmin,ss) and peak (Cmax,ss) concentrations of rivaroxaban between Asians and Caucasians and to evaluate the relationship between rivaroxaban concentrations and prothrombin time/international normalized ratio (PT/INR). Recruited patients were advised on the time to take rivaroxaban. Cmin,ss and PT/INR were taken when patients arrived. Cmax,ss and PT/INR were drawn between 2 and 4\u00a0h later after the patient took rivaroxaban with food. Thirty patients were included in the analyses: 57% (n\u2009=\u200917) males and 43% (n\u2009=\u200913) females, 77% (n\u2009=\u200923) on 20\u00a0mg and 23% (n\u2009=\u20097) on 15\u00a0mg. Median PTtrough and PTpeak are moderately correlated with Cmin,ss (r2\u2009=\u20090.43) and Cmax,ss (r2\u2009=\u20090.49), respectively. Patients on 15\u00a0mg have lower Cmin,ss and Cmax,ss versus Caucasians [12\u00a0ng/ml vs. 57\u00a0ng/ml (Cmin,ss); 87\u00a0ng/ml vs. 229\u00a0ng/ml (Cmax,ss), p\u2009<\u20090.01 for both]. Patients on 20\u00a0mg also have lower Cmin,ss and Cmax,ss versus Caucasians [14\u00a0ng/ml vs. 44\u00a0ng/ml (Cmin,ss); 101\u00a0ng/ml vs. 249\u00a0ng/ml (Cmax,ss), p\u2009<\u20090.01 for both]. Subgroup analysis shows patients with BMI\u2009\u2265\u200930 have lower Cmax,ss than patients with BMI\u2009<\u200930 [80.47\u00a0ng/ml vs. 124 (p\u2009=\u20090.014)]. Cmin,ss and Cmax,ss were lower in Singaporeans than Caucasians. This may have an impact on the effectiveness of rivaroxaban in Singaporeans. Patients with higher BMI may not benefit similarly as patients with lower BMI. Lastly, the Dade Innovin reagent's measure of PT/INR is not sensitive towards changes in rivaroxaban concentrations.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s11239-018-1726-y", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1113719", 
        "issn": [
          "0929-5305", 
          "1573-742X"
        ], 
        "name": "Journal of Thrombosis and Thrombolysis", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "4", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "46"
      }
    ], 
    "name": "Comparison of rivaroxaban concentrations between Asians and Caucasians and their correlation with PT/INR", 
    "pagination": "541-548", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "58b54577839fba0989efe63261574935e3107ec5cefa1150d6c27fbf626ccd23"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30155672"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "9502018"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s11239-018-1726-y"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1106387762"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s11239-018-1726-y", 
      "https://app.dimensions.ai/details/publication/pub.1106387762"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T01:15", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8697_00000557.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1007%2Fs11239-018-1726-y"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s11239-018-1726-y'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s11239-018-1726-y'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s11239-018-1726-y'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s11239-018-1726-y'


 

This table displays all metadata directly associated to this object as RDF triples.

159 TRIPLES      21 PREDICATES      43 URIs      21 LITERALS      9 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s11239-018-1726-y schema:about anzsrc-for:11
2 anzsrc-for:1117
3 schema:author Nd7822e934d5c4254a49a5c1061150f00
4 schema:citation sg:pub.10.1007/s00228-018-2450-4
5 sg:pub.10.1007/s11239-015-1317-0
6 sg:pub.10.1007/s40262-013-0100-7
7 sg:pub.10.1186/1477-9560-11-11
8 https://doi.org/10.1016/j.gpb.2016.03.008
9 https://doi.org/10.1016/j.jacc.2013.07.104
10 https://doi.org/10.1056/nejmoa1009638
11 https://doi.org/10.1056/nejmoa1300615
12 https://doi.org/10.1093/eurheartj/ehv466
13 https://doi.org/10.1111/j.1365-2125.2009.03390.x
14 https://doi.org/10.1253/circj.cj-12-0454
15 https://doi.org/10.2133/dmpk.dmpk-12-rg-034
16 https://doi.org/10.2174/1574884708666131111204658
17 https://doi.org/10.3109/0886022x.2011.605980
18 schema:datePublished 2018-11
19 schema:datePublishedReg 2018-11-01
20 schema:description The objectives of this study are to compare steady-state trough (Cmin,ss) and peak (Cmax,ss) concentrations of rivaroxaban between Asians and Caucasians and to evaluate the relationship between rivaroxaban concentrations and prothrombin time/international normalized ratio (PT/INR). Recruited patients were advised on the time to take rivaroxaban. Cmin,ss and PT/INR were taken when patients arrived. Cmax,ss and PT/INR were drawn between 2 and 4 h later after the patient took rivaroxaban with food. Thirty patients were included in the analyses: 57% (n = 17) males and 43% (n = 13) females, 77% (n = 23) on 20 mg and 23% (n = 7) on 15 mg. Median PT<sub>trough</sub> and PT<sub>peak</sub> are moderately correlated with Cmin,ss (r<sup>2</sup> = 0.43) and Cmax,ss (r<sup>2</sup> = 0.49), respectively. Patients on 15 mg have lower Cmin,ss and Cmax,ss versus Caucasians [12 ng/ml vs. 57 ng/ml (Cmin,ss); 87 ng/ml vs. 229 ng/ml (Cmax,ss), p &lt; 0.01 for both]. Patients on 20 mg also have lower Cmin,ss and Cmax,ss versus Caucasians [14 ng/ml vs. 44 ng/ml (Cmin,ss); 101 ng/ml vs. 249 ng/ml (Cmax,ss), p &lt; 0.01 for both]. Subgroup analysis shows patients with BMI ≥ 30 have lower Cmax,ss than patients with BMI &lt; 30 [80.47 ng/ml vs. 124 (p = 0.014)]. Cmin,ss and Cmax,ss were lower in Singaporeans than Caucasians. This may have an impact on the effectiveness of rivaroxaban in Singaporeans. Patients with higher BMI may not benefit similarly as patients with lower BMI. Lastly, the Dade Innovin reagent's measure of PT/INR is not sensitive towards changes in rivaroxaban concentrations.
21 schema:genre research_article
22 schema:inLanguage en
23 schema:isAccessibleForFree false
24 schema:isPartOf N5c5f11e441fc49ab80e25dc87884b8c0
25 N5fafbd3334884f569d6f12c95aeeac5a
26 sg:journal.1113719
27 schema:name Comparison of rivaroxaban concentrations between Asians and Caucasians and their correlation with PT/INR
28 schema:pagination 541-548
29 schema:productId N2d4e99c33e184dc0bd3c0b1e8ba5b131
30 N6b482e459f444b77a6be3651e600144d
31 N8b25179a5d6c4e60bbdf13b3217ed6e1
32 Ne1dab9a110c945acb1943708c986422a
33 Nf2c1e47b97834b5db0cb1b10d872b369
34 schema:sameAs https://app.dimensions.ai/details/publication/pub.1106387762
35 https://doi.org/10.1007/s11239-018-1726-y
36 schema:sdDatePublished 2019-04-11T01:15
37 schema:sdLicense https://scigraph.springernature.com/explorer/license/
38 schema:sdPublisher N253fbe6e3c3f4678bf4f6162d79aef76
39 schema:url https://link.springer.com/10.1007%2Fs11239-018-1726-y
40 sgo:license sg:explorer/license/
41 sgo:sdDataset articles
42 rdf:type schema:ScholarlyArticle
43 N0243be425cdd442983518a8b566b5e08 rdf:first N566f784135b945c3bca0c1d54c8e1a4e
44 rdf:rest N265e189cec5444aea244d41895f10019
45 N24337509ff7b43728a7281ab1b13125e rdf:first sg:person.0654504306.05
46 rdf:rest rdf:nil
47 N253fbe6e3c3f4678bf4f6162d79aef76 schema:name Springer Nature - SN SciGraph project
48 rdf:type schema:Organization
49 N265e189cec5444aea244d41895f10019 rdf:first sg:person.016423636335.12
50 rdf:rest N4dfd21a9bb564406b2ceda15aa41d045
51 N2d4e99c33e184dc0bd3c0b1e8ba5b131 schema:name doi
52 schema:value 10.1007/s11239-018-1726-y
53 rdf:type schema:PropertyValue
54 N4dfd21a9bb564406b2ceda15aa41d045 rdf:first sg:person.01255114517.29
55 rdf:rest N24337509ff7b43728a7281ab1b13125e
56 N566f784135b945c3bca0c1d54c8e1a4e schema:affiliation https://www.grid.ac/institutes/grid.415203.1
57 schema:familyName Lin
58 schema:givenName Yingying
59 rdf:type schema:Person
60 N5c5f11e441fc49ab80e25dc87884b8c0 schema:volumeNumber 46
61 rdf:type schema:PublicationVolume
62 N5fafbd3334884f569d6f12c95aeeac5a schema:issueNumber 4
63 rdf:type schema:PublicationIssue
64 N6b482e459f444b77a6be3651e600144d schema:name dimensions_id
65 schema:value pub.1106387762
66 rdf:type schema:PropertyValue
67 N78f60cfcb808470da3a16d837c23a9af rdf:first sg:person.010116702675.16
68 rdf:rest Na2fb32d4f8e04559a7edcd06db715df3
69 N8b25179a5d6c4e60bbdf13b3217ed6e1 schema:name readcube_id
70 schema:value 58b54577839fba0989efe63261574935e3107ec5cefa1150d6c27fbf626ccd23
71 rdf:type schema:PropertyValue
72 Na2fb32d4f8e04559a7edcd06db715df3 rdf:first sg:person.016236004310.40
73 rdf:rest N0243be425cdd442983518a8b566b5e08
74 Nbae195b3ed284a61867e9ae7dca6eb9a schema:affiliation https://www.grid.ac/institutes/grid.415203.1
75 schema:familyName Ng Tsai
76 schema:givenName Hobart Owen
77 rdf:type schema:Person
78 Nd7822e934d5c4254a49a5c1061150f00 rdf:first Nbae195b3ed284a61867e9ae7dca6eb9a
79 rdf:rest N78f60cfcb808470da3a16d837c23a9af
80 Ne1dab9a110c945acb1943708c986422a schema:name nlm_unique_id
81 schema:value 9502018
82 rdf:type schema:PropertyValue
83 Nf2c1e47b97834b5db0cb1b10d872b369 schema:name pubmed_id
84 schema:value 30155672
85 rdf:type schema:PropertyValue
86 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
87 schema:name Medical and Health Sciences
88 rdf:type schema:DefinedTerm
89 anzsrc-for:1117 schema:inDefinedTermSet anzsrc-for:
90 schema:name Public Health and Health Services
91 rdf:type schema:DefinedTerm
92 sg:journal.1113719 schema:issn 0929-5305
93 1573-742X
94 schema:name Journal of Thrombosis and Thrombolysis
95 rdf:type schema:Periodical
96 sg:person.010116702675.16 schema:affiliation https://www.grid.ac/institutes/grid.415203.1
97 schema:familyName Goh
98 schema:givenName Janice Jia Ni
99 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010116702675.16
100 rdf:type schema:Person
101 sg:person.01255114517.29 schema:affiliation https://www.grid.ac/institutes/grid.415281.b
102 schema:familyName Tiong
103 schema:givenName Lee Len
104 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01255114517.29
105 rdf:type schema:Person
106 sg:person.016236004310.40 schema:affiliation https://www.grid.ac/institutes/grid.415203.1
107 schema:familyName Aw
108 schema:givenName Jernice Wan Xin
109 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016236004310.40
110 rdf:type schema:Person
111 sg:person.016423636335.12 schema:affiliation https://www.grid.ac/institutes/grid.415281.b
112 schema:familyName Fong
113 schema:givenName Alan Yean Yip
114 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016423636335.12
115 rdf:type schema:Person
116 sg:person.0654504306.05 schema:affiliation https://www.grid.ac/institutes/grid.415203.1
117 schema:familyName Tan
118 schema:givenName Doreen Su-Yin
119 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0654504306.05
120 rdf:type schema:Person
121 sg:pub.10.1007/s00228-018-2450-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1101719494
122 https://doi.org/10.1007/s00228-018-2450-4
123 rdf:type schema:CreativeWork
124 sg:pub.10.1007/s11239-015-1317-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023938710
125 https://doi.org/10.1007/s11239-015-1317-0
126 rdf:type schema:CreativeWork
127 sg:pub.10.1007/s40262-013-0100-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037310382
128 https://doi.org/10.1007/s40262-013-0100-7
129 rdf:type schema:CreativeWork
130 sg:pub.10.1186/1477-9560-11-11 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050975774
131 https://doi.org/10.1186/1477-9560-11-11
132 rdf:type schema:CreativeWork
133 https://doi.org/10.1016/j.gpb.2016.03.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019579079
134 rdf:type schema:CreativeWork
135 https://doi.org/10.1016/j.jacc.2013.07.104 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050091443
136 rdf:type schema:CreativeWork
137 https://doi.org/10.1056/nejmoa1009638 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051578846
138 rdf:type schema:CreativeWork
139 https://doi.org/10.1056/nejmoa1300615 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006495123
140 rdf:type schema:CreativeWork
141 https://doi.org/10.1093/eurheartj/ehv466 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026416125
142 rdf:type schema:CreativeWork
143 https://doi.org/10.1111/j.1365-2125.2009.03390.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1015814013
144 rdf:type schema:CreativeWork
145 https://doi.org/10.1253/circj.cj-12-0454 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045133504
146 rdf:type schema:CreativeWork
147 https://doi.org/10.2133/dmpk.dmpk-12-rg-034 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024029267
148 rdf:type schema:CreativeWork
149 https://doi.org/10.2174/1574884708666131111204658 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069214254
150 rdf:type schema:CreativeWork
151 https://doi.org/10.3109/0886022x.2011.605980 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029965769
152 rdf:type schema:CreativeWork
153 https://www.grid.ac/institutes/grid.415203.1 schema:alternateName Khoo Teck Puat Hospital
154 schema:name Department of Pharmacy, Khoo Teck Puat Hospital, 90 Yishun Central, 768828, Singapore, Singapore
155 rdf:type schema:Organization
156 https://www.grid.ac/institutes/grid.415281.b schema:alternateName Sarawak General Hospital
157 schema:name Clinical Research Centre, Sarawak General Hospital, Jalan Hospital, 93586, Kuching, Sarawak, Malaysia
158 Consultant Cardiologist, Sarawak Heart Centre, Kuching - Samarahan Expressway, 94300, Kota Samarahan, Sarawak, Malaysia
159 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...